A middle aged female presented with following symptoms - Hirsutism,
fragility of skin, with easy bruising, broad purplish striae and signs of proximal myopathy.
The first step in confirming the diagnosis will be
Options:
1) Advice 24 hours urinary free cortisol excretion
2) Exclude exogenous Glucocorticoid use
3) Advice plasma ACTH estimation
4) Advice dexamethasone overnight test

1 Answer

Answer :

Correct Answer: 2) Exclude exogenous Glucocorticoid use

Related questions

Description : Which of the following techniques would be most useful in the differential diagnosis between ectopic Cushing's syndrome and pituitary dependent Cushing's disease. 1) Urine free cortisol 2) ... Dexamethasone suppression test 3) ACTH concentrations 4) Inferior petrosal sinus sampling 5) CRF test

Last Answer : Answers-4 Inferior petrosal sinus sampling with an elevated central ACTH concentration compared with the peripheral value is the most valuable test in the differential diagnosis of either Cushing's disease or ectopic Cushing's syndrome. The other tests are far less useful in comparison.

Description : 40 year old lady presented with swelling in the right side of the upper part of the neck below the ear lobule for last 10 years. Swelling is painless and gradually growing. On examination ... diagnosis Options: 1) Lipoma 2) Rhabdomyosarcoma 3) Chronic sialadenitis 4) Mixed parotid tumour

Last Answer : Correct Answer: 4) Mixed parotid tumour

Description : Which of the following is the most common cause of Hypothyroidism in iodine sufficient area? Options: 1) Iatrogenic hypothyroidism 2) Post-partum thyroiditis 3) Autoimmune thyroiditis 4) Thyroid aplasia

Last Answer : Correct Answer: 3) Autoimmune thyroiditis

Description : A 20 yr. old female patient presents with pain in thyroid region of the neck since few days. She gives recent history of mumps. On palpation thyroid is tender and her thyroid function ... 1) de Quervain's thyroiditis 2) Silent thyroiditis 3) Primary thyrotoxicosis 4) Hashimoto's thyroiditis

Last Answer : Correct Answer: 1) de Quervain’s thyroiditis

Description : A 53-year-old man presented with hypertension of 150/110 mmHg. He is generally asymptomatic and has no previous medical history of note. He is a smoker of 5 cigarettes daily and drinks ... Adrenocortical adenoma 2) Bartter's syndrome 3) Liddle's syndrome 4) Liquorice ingestion 5) Pheochromocytoma

Last Answer : Answers-1 This patient is most likely to have Conn's syndrome as reflected by the hypokalaemic hypertension. Liquorice ingestion or Liddle's syndrome are again possible causes of ... hypertension (often diastolic hypertension), muscular weakness, paresthesias, headache, polyuria, and polydipsia."

Description : Which of the following disorders is characterized by a group of symptoms produced by an excess of free circulating cortisol from the adrenal cortex? a) Cushing's syndrome The patient ... individual with Hashimoto's disease demonstrates inflammation of the thyroid gland, resulting in hypothyroidism.

Last Answer : a) Cushing’s syndrome The patient with Cushing’s syndrome demonstrates truncal obesity, moon face, acne, abdominal striae, and hypertension.

Description : True statements concerning hypoadrenal shock include which of the following? A. Adrenocortical insufficiency may manifest itself as severe shock refractory to volume and pressor therapy. B. ... test should be performed to help establish the diagnosis of acute adrenocortical insufficiency.

Last Answer : Answer: AD DISCUSSION: Shock due to acute adrenocortical insufficiency is relatively uncommon but must be considered when shock refractory to volume replacement and pressor therapy is present. ... and it is the corticosteroid of choice while the ACTH stimulation test is being performed

Description : A 55 year-old female complaining of vague tiredness is found to have a serum corrected calcium concentration of 2.9 mmol/l. Examination was unremarkable. Which of the following results ... 4) Low normal plasma phosphate concentration 5) Low normal serum 25-hydroxyvitamin D concentration

Last Answer : Answers-3 Bit too easy really. A high or even normal PTH concentration in the presence of hypercalcaemia would support the diagnosis of hyperparathyroidism. A high urinary Calcium concentration may ... but neither confirm the diagnosis. Elevated 1,25 VitD suggests a diagnosis of hypervitaminosis D.

Description : Which of the following statement(s) about epileptic seizure is/are correct (1) Jacksonian march represents spread of seizure activity over motor cortex (2) Focal seizures of temporal cortex cause psychic symptoms (3) Typical absence seizures are ... 1, 2 and 4 2) 3 and 4 3) 1 and 4 4) 2, 3 and 4

Last Answer : Correct Answer: 1) 1, 2 and 4

Description : Barium swallow study of a patient suffering from dysphagia revealed Bird's beak appearance of esophagus. The most probable diagnosis is Options: 1) Reflux esophagitis Barrett's esophagus 3) Hiatus hernia 4) Achalasia cardia

Last Answer : Correct Answer: 4) Achalasia cardia

Description : A person was unable to close his right eye. There is dribbling of saliva from right angle of his mouth and he in unable to make a pout. The probable diagnosis is Options: 1) Bell’s Palsy 2) Trigeminal Neuralgia 3) Optic Nerve Injury 4) Oculomotor Nerve Injury

Last Answer : Correct Answer: 1) Bell’s Palsy

Description : Which of the following statements regarding hypercalcemia are true? A. The symptoms of hypercalcemia may mimic some symptoms of hyperglycemia. B. Metastatic breast cancer is an unusual cause of ... fluid volume deficit. E. Urinary calcium excretion may be increased by vigorous volume repletion.

Last Answer : Answer: ADE DISCUSSION: Markedly elevated serum calcium levels produce polydipsia, polyuria, and thirst. Vigorous volume repletion and saline diuresis correct the extracellular fluid volume ... , from bony metastasis. The calcitonin effect on calcium is diminished with repeat administrations

Description : In which of the following chapter of Kent's Repertory of Homoeopathic Materia Medica, you will NOT find the rubric ‘Aphthae’. Options: 1) Face 2) Mouth 3) Genitalia - Female 4) Generalities

Last Answer : Correct Answer: 4) Generalities

Description : This remedy can be given in pertussis , after Drosera has relieved the severe symptoms Options: 1) Cina 2) Cuprum met. 3) Corallium rubrum 4) Euphrasia

Last Answer : 1) Cina

Description : Hahnemann conceived idea of Cinchona bark experiment during the translation of Options: 1) Monroe’s “Materia Medica” 2) Cullen’s “Treatise on Materia Medica” 3) Lewin’s “Secondary Effects of Remedies” 4) Herings “Guiding Symptoms of Materia Medica"

Last Answer : Correct Answer: 2) Cullen’s “Treatise on Materia Medica”

Description : Pseudocyesis includes the following features except Options: 1) Distension of abdomen 2) hCG levels double every 72 hours 3) Amenorrhoea 4) Morning Sickness

Last Answer : Correct Answer: 2) hCG levels double every 72 hours

Description : Which of following statement is incorrect according to BBCR Repertory Options: 1) Radiating pain is given under Sensation & Complaints in General 2) Typhoid fever is given under Fever - Pathological types 3) Pregnancy is given under Sexual Impulse 4) Tetters is given in Skin & Exterior body

Last Answer : Correct Answer: 3) Pregnancy is given under Sexual Impulse

Description : ‘Abscess in perineum’ is given in which chapter of Kent's Repertory Options: 1) Genitalia 2) Skin 3) Generalities 4) Rectum

Last Answer : Correct Answer: 4) Rectum

Description : Which of the following area is known as the dangerous area of the scalp Options: 1) Skin 2) Superficial Fascia 3) Deep Fascia 4) Loose Areolar Tissue

Last Answer : Correct Answer: 4) Loose Areolar Tissue

Description : The following glucocorticoid has significant mineralocorticoid activity also: A. Hydrocortisone B. Triamcinolone C. Dexamethasone D. Betamethasone

Last Answer : A. Hydrocortisone

Description : Urine examination (Benedict’s test) of a 40 yr old obese male showed a brick red precipitate. This can result from all except Options: 1) Diabetes Mellitus 2) Drugs 3) Acute post-streptococcal glomerulonephritis 4) Cushing’s syndrome

Last Answer : Correct Answer: 3) Acute post-streptococcal glomerulonephritis

Description : An 11 year old girl presents with the following complaints (1) Difficulty in climbing upstairs and combing her hair (2) Maculopapular rash over MCP joints (3) Gower's sign Positive. The most appropriate ... advised is Options: 1) ESR 2) Creatine Kinase 3) RA Factor 4) ANA antibodies test

Last Answer : Correct Answer: 2) Creatine Kinase

Description : Which of the following characteristic should be considered most important while applying a screening test in lethal disease like cancer Options: 1) Sensitivity 2) Specificity 3) Simplicity

Last Answer : Correct Answer: 1) Sensitivity

Description : Ascoli's thermoprecipition test helps in confirming the laboratory diagnosis of A- tetanus B- anthrax C- typhoid D- cholera

Last Answer : anthrax

Description : An early diagnosis of vitamin C deficiency can be made by (A) Measuring plasma ascorbic acid (B) Measuring urinary ascorbic acid (C) Ascorbic acid saturation test (D) All of these

Last Answer : Answer : C

Description : Laboratory diagnosis of vitamin B12 deficiency can be made by measuring the urinary excretion of (A) Xanthurenic acid (B) Formiminoglutamic acid (C) Methylmalonic acid (D) Homogentisic acid

Last Answer : Answer : C

Description : Keratotic lesion surrounded by cold web like lines /Wickham’s Striae/ appears as lace-like network on the buccal mucosa; you diagnosis is** A. Lichen Planus B. Keratosis follicularis C. White sponge nevus

Last Answer : A. Lichen Planus

Description : Cortisol is a (A) Glucocorticoid (B) Mineralocorticoid (C) Androgen (D) Estrogen

Last Answer : Answer : B

Description : The predominant glucocorticoid is (A) Cortisol (B) Aldosterone (C) Dehydroephiandrosterone (D) Androstenedione

Last Answer : Answer : A

Description : Which of the following hormones is considered a glucocorticoid? A) aldosterone B) insulin C) thyroxin D) cortisol E) parathyroid hormone

Last Answer : D) cortisol

Description : Purplish lesions on the buccal mucosa that have been there since birth; the diagnosis is: A. Haemangioma B. Erythema C. Naevus

Last Answer : A. Haemangioma

Description : The first edition of the Homeopathic Therapeutics of Diarrhoea by J.B Bell was published in Year Options: 1) 1869 2) 1879 3) 1881 4) 1882

Last Answer : Correct Answer: 1) 1869

Description : Out of the following, which is the most ideal time for insertion of an intra uterine contraceptive device? Options: 1) Immediate post-partum i.e. within first week of delivery2) Post- ... after delivery 3) Immediately after second trimester legal abortion 4) During last week of menstrual cycle

Last Answer : Correct Answer: 2) Post-puerperal i.e. 6-8 weeks after delivery

Description : Which of the following is the most common cause of Hypothyroidism in iodine sufficient area? Options: 1) Iatrogenic hypothyroidism 2) Post-partum thyroiditis 3) Autoimmune thyroiditis 4) Thyroid aplasia

Last Answer : Correct Answer: 3) Autoimmune thyroiditis

Description : Sjogren’s syndrome is a chronic disease characterized by which of the following clinical feature: Options: 1) Esophageal dysmotility 2) Keratoconjunctivitis sicca 3) Widespread damage to small blood vessels 4) Libmann Sachs Endocardititis

Last Answer : Correct Answer: 2) Keratoconjunctivitis sicca

Description : Serum ferritin is a maker of Options: 1) Circulating Iron 2) Storage iron 3) Folate 4) Vitamin B12 Levels

Last Answer : Correct Answer: 2) Storage iron

Description : Hemophilia A is characterised by deficiency of Options: 1) Factor VII 2) Factor VIII 3) Factor IX 4) Factor XI

Last Answer : Correct Answer: 2) Factor VIII

Description : Red infarct are seen in Options: 1) Lungs 2) Kidneys 3) Spleen 4) Bones

Last Answer : Correct Answer: 1) Lungs

Description : Which remedy has vomiting, bilious with anxiety and weak pulse, every month after mensturation, cannot lie on right side or back without instantly producing dark green vomiting. Options: 1) Argentum nitricum 2) Antimonium tart. 3) Crotalus horridus 4) Carbolic acid

Last Answer : Correct Answer: 3) Crotalus horridus

Description : Which of the following medicine is not included in Nash’s trio of weakness. Options: 1) Carbo veg. 2) Arsenicum album 3) Muriatic acid 4) Cinchona

Last Answer : Correct Answer: 4) Cinchona

Description : Diarrhoea like dirty water, from fruit or sour krout is seen in Options: 1) Cinchona 2) Croton tig. 3) Petroleum 4) Bryonia alba

Last Answer : Correct Answer: 4) Bryonia alba

Description : According to J.T. Kent, one of the best remedies for retention of urine in the new born is Options: 1) Chamomilla 2) Podophyllum 3) Aconitum napellus 4) Dulcamara

Last Answer : Correct Answer: 3) Aconitum napellus

Description : Asthma worse in foggy weather and relieved by profuse perspiration, is seen in Options: 1) Hypericum 2) Lachesis 3) Sambucus 4) Carbo veg.

Last Answer : Correct Answer: 1) Hypericum

Description : Which of the following has drum stick appearance Options: 1) Clostridium tetani 2) Pneumococcus 3) Streptococcus pneumoniae 4) Staphylococcus epidermis

Last Answer : Correct Answer: 1) Clostridium tetani

Description : Which is the most common site of pressure sore Options: 1) Sacrum 2) Heel 3) Ischium 4) Greater Trochanter

Last Answer : Correct Answer: 3) Ischium

Description : Radiological ‘Colon cut off sign’ is seen in Options: 1) Acute intussusception 2) Acute lobar pneumonia 3) Acute pancreatitis 4) Crohn’s disease

Last Answer : Correct Answer: 3) Acute pancreatitis

Description : Which among the following BIRADS category is highly suggestive of malignancy Options: 1) BIRADS- V 2) BIRADS – III 3) BIRADS-II 4) BIRADS- 0

Last Answer : Correct Answer: 1) BIRADS- V

Description : Among the following which is not the feature of Paget’s disease of Breast Options: 1) Itching 2) Unilateral presentation 3) Nipples usually destroyed 4) Underlying lump is usually present

Last Answer : Correct Answer: 1) Itching

Description : Kehr’s sign is a classical feature of Options: 1) Rupture of liver 2) Acute pancreatitis 3) Acute intestinal obstruction 4) Rupture of spleen

Last Answer : Correct Answer: 4) Rupture of spleen

Description : Which of the following medical sign is observed in Latent Tetany Options: 1) Trousseau’s sign 2) Pratt’s sign 3) Blumberg’s sign 4) Fox’s sign

Last Answer : Correct Answer: 1) Trousseau’s sign