Dolichol phosphate is
A- a complex lipid involved in docking vesicles with the plasma membrane
B- the anchor on which sugars assemble before transfer to proteins
C- a chaperone used in protein folding
D- a product of phospholipase C activation

1 Answer

Answer :

the anchor on which sugars assemble before transfer to proteins

Related questions

Description : Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane

Last Answer : C) production of new proteins

Description : The transport of proteins out of the cell is termed exocytosis. Which of the following statement(s) is/are true concerning this process? a. Secretory vesicles fuse with the plasma membrane b. ... or a neurotransmitter d. A decrease in cytoplasmic calcium occurs as part of the secretion process

Last Answer : Answer: a, b, c Transport vesicles that bud off the Golgi network carry both material to be secreted from the cell and protein destined to become components of the plasma ... but may also involve generation of diacylglycerol or production of cyclic AMP which activate kinases or phosphatases

Description : The last step in synthesis of peptidoglycan is A- attachment of a peptide to muramic acid B- attaching two amino acids to form a cross-link C- attachment of a portion of peptidoglycan to a membrane lipid D- binding of penicillin to a membrane protein

Last Answer : attaching two amino acids to form a cross-link

Description : Which of the following statement(s) is/are true concerning the cell plasma membrane? a. The plasma membrane is composed of amphipathic molecules b. The hydrophobic core of the lipid bilayer of the ... contribute to the cell coat d. The membrane proteins of nerve cells are highly voltage-dependent

Last Answer : Answer: a, b, d The plasma membrane defines the boundary of the cell and serves to contain and concentrate enzymes and other macromolecule constituents. The plasma membrane is ... and bear carbohydrate moieties primarily as oligosaccharide chains that contribute to the cell coat or glycocalyx

Description : The Golgi complex participates in (a) fatty acid breakdown (b) formation of secretory vesicles (c) respiration in bacteria (d) activation of amino acid

Last Answer : b) formation of secretory vesicles

Description : The Golgi complex participates in (1) Fatty acid breakdown (2) Formation of secretory vesicles (3) Respiration in bacteria (4) Activation of amino acid

Last Answer : (2) Formation of secretory vesicles

Description : Answer: a, b, c, d Free oxygen radicals are chemical species that are intermediates in the normal process of cellular respiration. Oxidants that are free radicals have been implicated as initiators of ... a. C-reactive protein b. Serum amyloid c. a -Proteinase inhibitor d. Fibrinogen e. Albumin

Last Answer : Answer: a, b, c, d The acute-phase response is a series of homeostatic responses of the organism to tissue injury in infection and inflammation. After an inflammatory stimulus occurs, a number ... 30% to 50% of the level before injury. The reason for the decrease in production is poorly understood

Description : The mode of action of polymyxin is to A- inhibit protein synthesis B- inhibit DNA synthesis C- injury to the plasma membrane D- inhibit folic acid synthesis

Last Answer : injury to the plasma membrane

Description : Fibrinolytic therapy is based on activation of plasminogen, the inactive proteolytic enzyme of plasma that binds to fibrin during the formation of thrombosis. Activation of plasminogen to plasmin results ... TPA all exceed 30 minutes d. Streptokinase is significantly cheaper than urokinase or TPA

Last Answer : Answer: a, b, d Streptokinase is a bacterial protein produced by group C b-hemolytic streptococci. It is therefore antigenic in humans and can be associated with allergic reaction in ... one agent over the other. Streptokinase however, is markedly less expensive than either urokinase or TPA

Description : A _____ is a protein receptor on the surface of macrophages, dendritic cells, and endothelial cells that allow them to recognize foreign cell markers. a. Toll-like receptor (TLR) b. pathogen-associated c. Membrane attack complex (MAC) d. Natural killer cells (NK)

Last Answer : b. pathogen-associated

Description : Which of the following proteins would not need localization signal? A- A nuclear protein B- A cytosolic protein C- A protein bound to the endoplasmic reticulum (ER) membrane D- A cell surface protein

Last Answer : A cytosolic protein

Description : Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in inflammatory processes are produced from arachidonic acid by (a) ... 2 (c) Glutathione - S - transferase (d) Lipoxygenase (e) Phospholipase A2

Last Answer : Ans: B

Description : Proteins that are secreted by cells are generally a. not synthesized on membrane-bound ribosomes b. initially synthesized with a signal peptide or leader sequence at their C terminal c. found in ... endocytosis e. secreted in a form that is larger than the form present in the endoplasmic reticulum

Last Answer : found in vesicles and secretory granules

Description : Chemically an antigen may be A- lipid B- protein C- polysaccharide D- any of these

Last Answer : any of these

Description : Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the ... activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.

Last Answer : C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes.

Description : The plasma membrane consists mainly of (a) phospholipids embedded in a protein bilayer (b) proteins embedded in a phospholipid bilayer (c) proteins embedded in a polymer of glucose molecules (d) proteins embedded in a carbohydrate bilayer

Last Answer : (b) proteins embedded in a phospholipid bilayer

Description : The mechanism of action of cyclosporine involves (a) Activation of calcineurin (b) Binding to cyclophilin to cause inhibition of a cytoplasmic phosphatase (c) Blockade of interleukin – 2- receptors (d) Inhibition of phospholipase A2 (e) Suppression of bone marrow progenitors

Last Answer : Ans: B

Description : Which of the following is the least likely to be involved in stabilising the three-dimensional folding of most proteins (a) Hydrogen bonds (b) Electrostatic interaction (c) Hydrophobic interaction (d) Ester bonds

Last Answer : (d) Ester bonds

Description : The latest model for plasma membrane is (a) lamellar model (b) unit membrane model (c) fluid mosaic model (d) molecular lipid model.

Last Answer : (c) fluid mosaic model

Description : Which of the following features is predicted by the Nicolson–Singer fluid mosaic model of biological membranes? (A) Membrane lipids do not diffuse laterally (B) Membrane lipid is primarily in a monolayer form (C) Membrane lipids freely flip-flop (D) Membrane proteins may diffuse laterally

Last Answer : Answer : D

Description : According to widely accepted fluid mosaic model cell membranes are semi-fluid, where lipids and integral proteins can diffuse randomly. In recent years, this model has been modified in several ... domains of the membrane. (d) Many proteins remain completely embedded within the lipid bilayer.

Last Answer : (b) Proteins can also undergo flip-flop movements in the lipid bilayer.

Description : Keeping in view the fluid mosaic model' for the structure of cell membrane, which one of the following statement is correct with respect to the movements of lipids and proteins from one lipid ... ) Both lipids and proteins can flip-flop (d) While lipids can rarely flip-flop, proteins cannot.

Last Answer : (d) While lipids can rarely flip-flop, proteins cannot.

Description : Antifungal drugs, such as_ __, inhibit proper formation of a. Miconazole; A Plasma Membrane b. Griseofulvin; Dna c. Ketoconazole; A Cell Wall d. Tiucytosine; A Rnicrotubule

Last Answer : d. Tiucytosine; A Rnicrotubule

Description : The formation of _____ by_____ directly lyses and kills pathogens. a. Membrane Attack Complexes, complement b. Inflammation, lymph nodes c. antibodies, plasma cells d. Plasma cells, B cells

Last Answer : a. Membrane Attack Complexes, complement

Description : The gram-positive bacteria lack __________ structure/component? A.outer membrane  B.murein C.teichoic acid  D.plasma membrane

Last Answer : A.outer membrane

Description : All of the following are found in prokaryotes and eukaryotes, except a. acell (plasma) membrane b. mitochondria c. cytoplasm d. ribosome

Last Answer : b. mitochondria

Description : Folding of newly synthesized proteins is accelerated by (A) Protein disulphide isomerase (B) Prolyl cis-trans isomerase (C) Chaperonins (D) All of these

Last Answer : Answer : D

Description : Tertiary structure of a protein describes (A) The order of amino acids (B) Location of disulphide bonds (C) Loop regions of proteins (D) The ways of protein folding

Last Answer : Answer : D

Description : Which of the following statements regarding the complement system are true? a. Complement activation yields products which are directly cytotoxic as well as products which act indirectly via activated ... and classical pathways converge proximal to generating the membrane attack complex (C5b-9)

Last Answer : Answer: a, d The complement system is composed of two different but linked sequences, the classic and alternative pathways. The pathways involve serum proteins that act to amplify the inflammatory-immune ... the C5 level proximal to generating the membrane attack complex (C5b-9) (Figure 6-3)

Description : Which of the following statement describes plasmids? A- Another name for a protoplast B- A complex membrane structure that covers the chromosome of bacteria Small, circular DNA molecules that can exist independently of chromosomes commonly C- found in bacteria D- None of the above

Last Answer : found in bacteria

Description : Which of the following statements are true of oxidants? A. In addition to their pathophysiologic roles in inflammation, injury, and infection, oxidants also have physiologic roles. B. Oxidants may ... involved the catalytic production of superoxide anion (O 2 ) by the enzyme xanthine oxidase.

Last Answer : Answer: ABCD DISCUSSION: Oxidants are reactive oxygen metabolites that have both physiologic and pathophysiologic roles. As potent oxidizing agents, oxidants are involved in cytochrome P ... leukocyte infiltration and activation, causing further tissue damage by the release of cytotoxic proteases

Description : . MHC class I proteins would be found on___________ whereas MHC class II proteins would be found on_____________ a. Nucleated Cells; Plasma Cells b. Nucleated Cells; Macrophages c. Dendritic Cells; Neutrophils d. Only White Blood Cells; Red Blood Cells

Last Answer : b. Nucleated Cells; Macrophages

Description : A red, itchy rash that forms small, teardrop-shaped, fluid-filled vesicles is typical of a. Measles. b. Rubella. c. Chickenpox. d. Mumps.

Last Answer : c. Chickenpox.

Description : How many high-energy phosphate bond equivalents are required for amino acid activation in protein synthesis? (A) One (B) Two (C) Three (D) Four

Last Answer : Answer : B

Description : In the process of activation of amino acids for protein synthesis, the number of high energy phosphate bond equivalent utilised is (A) 0 (B) 1 (C) 2 (D) 4

Last Answer : Answer : C

Description : Enzymes combine with a ___________at the___________ site to lower the activation energy. a. Substrate; Active b. Product; Noncompetitive c. Product; Active d. Coenzyme; Active

Last Answer : a. Substrate; Active

Description : If a drug has a constant bioavailability and first order elimination, its maintenance dose rate will be directly proportional to its: A. Volume of distribution B. Plasma protein binding C. Lipid solubility D. Total body clearance

Last Answer : D. Total body clearance

Description : Glomerular filtration of a drug is affected by its: A. Lipid solubility B. Plasma protein binding C. Degree of ionization D. Rate of tubular secretion

Last Answer : B. Plasma protein binding

Description : 5 A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Last Answer : D. Redistribution

Description : Marked redistribution is a feature of: A. Highly lipid soluble drugs B. Poorly lipid soluble drugs C. Depot preparations D. Highly plasma protein bound drugs

Last Answer : A. Highly lipid soluble drugs

Description : The following attribute of a drug tends to reduce its volume of distribution: A. High lipid solubility B. Low ionisation at physiological pH values C. High plasma protein binding D. High tissue binding

Last Answer : C. High plasma protein binding

Description : A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Last Answer : D. Redistribution

Description : Marked redistribution is a feature of: A. Highly lipid soluble drugs B. Poorly lipid soluble drugs C. Depot preparations D. Highly plasma protein bound drugs

Last Answer : A. Highly lipid soluble drugs

Description : The following attribute of a drug tends to reduce its volume of distribution: A. High lipid solubility B. Low ionisation at physiological pH values C. High plasma protein binding D. High tissue binding

Last Answer : C. High plasma protein binding

Description : If a drug has a constant bioavailability and first order elimination, its maintenance dose rate will be directly proportional to its: A. Volume of distribution B. Plasma protein binding C. Lipid solubility D. Total body clearance

Last Answer : D. Total body clearanc

Description : Glomerular filtration of a drug is affected by its: A. Lipid solubility B. Plasma protein binding C. Degree of ionization D. Rate of tubular secretion

Last Answer : B. Plasma protein binding

Description : A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Last Answer : D. Redistribution

Description : Marked redistribution is a feature of: A. Highly lipid soluble drugs B. Poorly lipid soluble drugs C. Depot preparations D. Highly plasma protein bound drugs

Last Answer : A. Highly lipid soluble drugs

Description : The following attribute of a drug tends to reduce its volume of distribution: A. High lipid solubility B. Low ionisation at physiological pH values C. High plasma protein binding D. High tissue binding

Last Answer : C. High plasma protein binding

Description : Phospholipase A2 is an enzyme which removes a fatty acid residue from lecithin to form (A) Lecithin fragments (B) Phosphotidic acid (C) Glyceryl phosphate (D) Lysolecithin

Last Answer : Answer : D