. Sickle-cell anaemia is (a) caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin (b) caused by a change in a single base pair of DNA (c) characterized by elongated sickle like RBCs with a nucleus (d) an autosomal linked dominant trait.

. Sickle-cell anaemia is
(a) caused by substitution of valine by glutamic
acid in the beta globin chain of haemoglobin
(b) caused by a change in a single base pair of DNA
(c) characterized by elongated sickle like RBCs
with a nucleus
(d) an autosomal linked dominant trait.
by

1 Answer

Answer :

(b) caused by a change in a single base pair of DNA
by

Related questions

Select the correct match. (a) Haemophilia – Y linked (b) Phenylketonuria – Autosomal dominant trait(c) Sickle cell anaemia – Autosomal recessive trait,chromosome -11 (d) Thalassemia – X linked

Description : Select the correct match. (a) Haemophilia – Y linked (b) Phenylketonuria – Autosomal dominant trait (c) Sickle cell anaemia – Autosomal recessive trait,chromosome -11 (d) Thalassemia – X linked

Last Answer : (c) Sickle cell anaemia – Autosomal recessive trait,chromosome -11

Sickle cell anemia is caused a) When valine is replaced by glutamic acid in beta polypeptide chain b) When glutamic acid is replaced by valine in beta polypeptide chain c) When glutamic acid is replaced by valine in alpha polypeptide chain d) When valine is replaced by glutamic acid in alpha polypeptide chain

Description : Sickle cell anemia is caused a) When valine is replaced by glutamic acid in beta polypeptide chain b) When glutamic acid is replaced by valine in beta polypeptide chain c) When ... valine in alpha polypeptide chain d) When valine is replaced by glutamic acid in alpha polypeptide chain

Last Answer : b) When glutamic acid is replaced by valine in beta polypeptide chain

Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement. (a) Both are due to a quantitative defect in globin chain synthesis. (b) Thalassemia is due to less synthesis of globin molecules. (c) Sickle cell anaemia is due to a quantitative problem of globin molecules. (d) Both are due to a qualitative defect in globin chain synthesis.

Description : Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement. (a) Both are due to a quantitative defect in globin chain synthesis. (b ... problem of globin molecules. (d) Both are due to a qualitative defect in globin chain synthesis.

Last Answer : (b) Thalassemia is due to less synthesis of globin molecules

Pick out the correct statements. (1) Haemophilia is a sex-linked recessive disease. (2) Down’s syndrome is due to aneuploidy. (3) Phenylketonuria is an autosomal recessive gene disorder. (4) Sickle cell anaemia is an X-linked recessive gene disorder. (a) (1), (3) and (4) are correct. (b) (1), (2) and (3) are correct. (c) (1) and (4) are correct. (d) (2) and (4) are correct.

Description : Pick out the correct statements. (1) Haemophilia is a sex-linked recessive disease. (2) Down's syndrome is due to aneuploidy. (3) Phenylketonuria is an autosomal recessive gene disorder. (4) Sickle cell anaemia is an X- ... are correct. (c) (1) and (4) are correct. (d) (2) and (4) are correct.

Last Answer : (b) (1), (2) and (3) are correct.

Sickle cell anaemia induce to (a) change of amino acid in a-chain of haemoglobin (b) change of amino acid in b-chain of haemoglobin (c) change of amino acid in both a and b chains of haemoglobin (d) change of amino acid either a or b chains of haemoglobin.

Description : Sickle cell anaemia induce to (a) change of amino acid in a-chain of haemoglobin (b) change of amino acid in b-chain of haemoglobin (c) change of amino acid in both a and b chains of haemoglobin (d) change of amino acid either a or b chains of haemoglobin.

Last Answer : (b) change of amino acid in b-chain of haemoglobin

Which of the statements give below is correct with respect to frameshift mutation a) a single nucleotide base change, insertion, or deletion of the genetic material b) Glutamine is replaced by valine c) Sickle cell anemia is an example d) insertions or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.

Description : Which of the statements give below is correct with respect to frameshift mutation a) a single nucleotide base change, insertion, or deletion of the genetic material b) Glutamine is replaced by valine c) ... or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.

Last Answer : d) insertions or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.

.A disease caused by an autosomal primary non- disjunction is (a) Klinefelter’s syndrome (b) Turner’s syndrome (c) Sickle cell anaemia (d) Down’s syndrome.

Description : .A disease caused by an autosomal primary non- disjunction is (a) Klinefelter’s syndrome (b) Turner’s syndrome (c) Sickle cell anaemia (d) Down’s syndrome.

Last Answer : (d) Down’s syndrome.

Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement : (1) Both are due to a quantitative defect in globin chain synthesis (2) Thalassemia is due to less synthesis of globin molecules (3) Sickel cell anemia is due to a quantitative problem of globin molecules (4) Both are due to a qualitative defect in globin chain synthesis

Description : Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement : (1) Both are due to a quantitative defect in globin chain synthesis (2 ... problem of globin molecules (4) Both are due to a qualitative defect in globin chain synthesis

Last Answer : (2) Thalassemia is due to less synthesis of globin molecules

Which type of Mendelian inherited condition results in both genders being affected equally in a vertical pattern? a) Automosomal dominant inheritance An individual who has an autosomal dominant inherited condition carries a gene mutation for that condition on one chromosome of a pair. b) Automosomal recessive inheritance The pattern of inheritance in autosomal recessive inherited conditions is different from that of autosomal dominant inherited conditions in that it is more horizontal than vertical, with relatives of a single generation tending to have the condition. c) X-linked inheritance X-linked conditions may be inherited in families in recessive or dominant patterns.

Description : Which type of Mendelian inherited condition results in both genders being affected equally in a vertical pattern? a) Automosomal dominant inheritance An individual who has an autosomal dominant ... that combine during early embryonic development leading to incomplete closure of the neural tube.

Last Answer : a) Automosomal dominant inheritance An individual who has an autosomal dominant inherited condition carries a gene mutation for that condition on one chromosome of a pair.

Abnormal chain of amino acids in sickle cell anaemia is (A) Alpha chain (B) Beta chain (C) Delta chain (D) Gama chain

Description : Abnormal chain of amino acids in sickle cell anaemia is (A) Alpha chain (B) Beta chain (C) Delta chain (D) Gama chain

Last Answer : Answer : B

Abnormal chain of amino acids in sickle cells anaemia is (A) Alpha chain (B) Beta chain (C) Gama chain (D) Delta chain

Description : Abnormal chain of amino acids in sickle cells anaemia is (A) Alpha chain (B) Beta chain (C) Gama chain (D) Delta chain

Last Answer : Answer : B

Which of the following statements concerning abnormalities of the haemoglobin molecule is true? 1) Alpha thalassaemia is due to a deficiency of beta-chain production 2) HbS is caused by a single base mutation on the beta-chain 3) genes for the alpha and beta chains are located on the same chromosome 4) in thalassaemia persistance of HbF is an adverse prognostic sign 5) oliguneoclitide probes may assist in the diagnosis of haemoglobinopathies

Description : Which of the following statements concerning abnormalities of the haemoglobin molecule is true? 1) Alpha thalassaemia is due to a deficiency of beta-chain production 2) HbS is caused by a ... is an adverse prognostic sign 5) oliguneoclitide probes may assist in the diagnosis of haemoglobinopathies

Last Answer : Answers-2 Alpha Thalassaemia is due to abnormalities of the alpha chain. Persistence of HbF has survival advnatages in severely affected subjects. C-alpha 16, beta 11. e-Hb electrophoresis(Dr Shu Ho)

.Represented here is the inheritance pattern of a certain type of trait in humans. Which one of the following conditions could be an example of this pattern? (a) Phenylketonuria (b) Sickle cell anaemia (c) Haemophilia (d) Thalassemia

Description : .Represented here is the inheritance pattern of a certain type of trait in humans. Which one of the following conditions could be an example of this pattern? (a) Phenylketonuria (b) Sickle cell anaemia (c) Haemophilia (d) Thalassemia

Last Answer : (c) Haemophilia

Sickle cell anaemia has not been eliminated from the African population because (a) it is controlled by dominant genes (b) it is controlled by recessive genes (c) it is not a fatal disease (d) it provides immunity against malaria

Description : Sickle cell anaemia has not been eliminated from the African population because (a) it is controlled by dominant genes (b) it is controlled by recessive genes (c) it is not a fatal disease (d) it provides immunity against malaria

Last Answer : (d) it provides immunity against malaria.

Haemoglobin SC disease: a. is common amongst Afro-carribean people b. does not show sickle cells in the blood film. c. causes severe anaemia d. causes retinal vein occlusion

Description : Haemoglobin SC disease: a. is common amongst Afro-carribean people b. does not show sickle cells in the blood film. c. causes severe anaemia d. causes retinal vein occlusion

Last Answer : causes retinal vein occlusion

Which one is the incorrect statement with regard to the importance of pedigree analysis? (a) It confirms that DNA is the carrier of genetic information. (b) It helps to understand whether the trait in question is dominant or recessive. (c) It confirms that the trait is linked to one of the autosome. (d) It helps to trace the inheritance of a specific trait.

Description : Which one is the incorrect statement with regard to the importance of pedigree analysis? (a) It confirms that DNA is the carrier of genetic information. (b) It helps to understand whether the trait in ... linked to one of the autosome. (d) It helps to trace the inheritance of a specific trait.

Last Answer : (a) It confirms that DNA is the carrier of genetic information.

Study the pedigree chart given below. What does it show? (a) Inheritance of a condition like phenylketonuria as an autosomal recessive trait. (b) The pedigree chart is wrong as this is not possible. (c) Inheritance of a recessive sex-linked disease like haemophilia. (d) Inheritance of a sex-linked inborn error of metabolism like phenylketonuria

Description : Study the pedigree chart given below. What does it show? (a) Inheritance of a condition like phenylketonuria as an autosomal recessive trait. (b) The pedigree chart is wrong as this is ... disease like haemophilia. (d) Inheritance of a sex-linked inborn error of metabolism like phenylketonuria

Last Answer : (a) Inheritance of a condition like phenylketonuria as an autosomal recessive trait.

What type of inheritance pattern (are the A and B alleles to each other (Autosomal dominant-Regular dominant-recessive relationship, X linked, co-dominant, incomplete dominant)?

Description : What type of inheritance pattern (are the A and B alleles to each other (Autosomal dominant-Regular dominant-recessive relationship, X linked, co-dominant, incomplete dominant)?

Last Answer : Incomplete dominance

Inheritance of primary gout is (A) Autosomal recessive (B) Autosomal dominant (C) X-linked recessive (D) X-linked dominant

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Last Answer : Answer : C

.A diseased man marries a normal woman. They get three daughters and five sons. All the daughters were diseased and sons were normal. The gene of this disease is (a) sex linked dominant (b) sex linked recessive (c) sex limited character (d) autosomal dominant.

Description : .A diseased man marries a normal woman. They get three daughters and five sons. All the daughters were diseased and sons were normal. The gene of this disease is (a) sex linked dominant (b) sex linked recessive (c) sex limited character (d) autosomal dominant.

Last Answer : (a) sex linked dominant

A man and a woman, who do not show any apparent signs of a certain inherited disease, have seven children (2 daughters and 5 sons). Three of the sons suffer from the given disease but none of the daughters affected. Which of the following mode of inheritance do you suggest for this disease? (a) Sex-linked dominant (b) Sex-linked recessive (c) Sex-limited recessive (d) Autosomal dominant

Description : A man and a woman, who do not show any apparent signs of a certain inherited disease, have seven children (2 daughters and 5 sons). Three of the sons suffer from the given disease but none ... ? (a) Sex-linked dominant (b) Sex-linked recessive (c) Sex-limited recessive (d) Autosomal dominant

Last Answer : (b) Sex-linked recessive

n the following human pedigree, the filled symbols represent the affected individuals. Identify the type of given pedigree. (i) (ii) (iii) (iv) (a) Autosomal recessive (b) X-linked dominant (c) Autosomal dominant (d) X-linked recessive

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Last Answer : (a) Autosomal recessive

Which among the following is an essential amino acid for man? (A) Alanine (B) Serine (C) Valine (D) Glutamic acid

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Last Answer : Answer : C

Which one of the amino acids could serve as the best buffer at pH 7? (A) Glutamic acid (B) Arginine (C) Valine (D) Histidine

Description : Which one of the amino acids could serve as the best buffer at pH 7? (A) Glutamic acid (B) Arginine (C) Valine (D) Histidine

Last Answer : Answer : D

Identify the basic amino acid from the following. (a) Tyrosine (b) Glutamic Acid (c) Lysine (d) Valine

Description : Identify the basic amino acid from the following. (a) Tyrosine (b) Glutamic Acid (c) Lysine (d) Valine

Last Answer : (c) Lysine

Mr. Kapoor has Bb autosomal gene pair and d allele sex-linked. What shall be proportion of Bd in sperms? (a) Zero (b) 1/2 (c) 1/4 (d) 1/8

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Last Answer : (c) 1/4

How is analyzing the inheritance patterns of sickle cell disease through pedigrees allowed scientists to determine that the disease is autosomal recessive?

Description : How is analyzing the inheritance patterns of sickle cell disease through pedigrees allowed scientists to determine that the disease is autosomal recessive?

Last Answer : Feel Free to Answer

Blood cancer is commonly known as – (1) Leucoderma (2) Leukaemia (3) Haemophilia (4) Sickle-cell. anaemia

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Last Answer : (2) Leukaemia Explanation: Leukemia is a cancer of blood and bone marrow. When a person has leukemia, the body makes too many white blood cells (leukocytes). The causes of most types of leukemia are not known. In general, all cancers have a breakdown in the normal way cell division is controlled.

The oxygen dissociation curve is shifted to the right with: a. polycythaemia b. pyrexia c. respiratory acidosis d. sickle cell anaemia

Description : The oxygen dissociation curve is shifted to the right with: a. polycythaemia b. pyrexia c. respiratory acidosis d. sickle cell anaemia

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Which of the following is a correct match? (a) Down’s syndrome - 21st chromosome (b) Sickle cell anaemia - X-chromosome (c) Haemophilia - Y-chromosome (d) Parkinson’s disease - X and Y chromosome

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Last Answer : a) Down’s syndrome - 21st chromosome

.Which one of the following conditions though harmful in itself, is also potential saviour from a mosquito borne infectious disease ? (a) Thalassaemia (b) Sickle cell anaemia (c) Pernicious anaemia (d) Leukaemia

Description : .Which one of the following conditions though harmful in itself, is also potential saviour from a mosquito borne infectious disease ? (a) Thalassaemia (b) Sickle cell anaemia (c) Pernicious anaemia (d) Leukaemia

Last Answer : (b) Sickle cell anaemia

Both sickle cell anaemia and Huntington’s chorea are (a) virus-related diseases (b) bacteria-related diseases (c) congenital disorders (d) pollutant-induced disorders.

Description : Both sickle cell anaemia and Huntington’s chorea are (a) virus-related diseases (b) bacteria-related diseases (c) congenital disorders (d) pollutant-induced disorders.

Last Answer : c) congenital disorders

The most striking example of point mutation is found in a disease called (a) Down’s syndrome (b) sickle cell anaemia (c) thalassaemia (d) night blindness.

Description : The most striking example of point mutation is found in a disease called (a) Down’s syndrome (b) sickle cell anaemia (c) thalassaemia (d) night blindness.

Last Answer : (b) sickle cell anaemia

Which of the following is an example of pleiotropy? (a) Haemophilia (b) Thalassemia (c) Sickle cell anaemia (d) Colour blindness

Description : Which of the following is an example of pleiotropy? (a) Haemophilia (b) Thalassemia (c) Sickle cell anaemia (d) Colour blindness

Last Answer : (c) Sickle cell anaemia

A polygenic inheritance in human beings is (a) skin colour (b) phenylketonuria (c) colour blindness (d) sickle cell anaemia

Description : A polygenic inheritance in human beings is (a) skin colour (b) phenylketonuria (c) colour blindness (d) sickle cell anaemia

Last Answer : (a) skin colour

In human beings, multiple genes are involved in the inheritance of (a) sickle-cell anaemia (b) skin colour (c) colour blindness (d) phenylketonuria.

Description : In human beings, multiple genes are involved in the inheritance of (a) sickle-cell anaemia (b) skin colour (c) colour blindness (d) phenylketonuria.

Last Answer : ) skin colour

Multiple alleles control inheritance of (a) phenylketonuria (b) colour blindness (c) sickle cell anaemia (d) blood groups.

Description : Multiple alleles control inheritance of (a) phenylketonuria (b) colour blindness (c) sickle cell anaemia (d) blood groups.

Last Answer : (d) blood groups.

Which one of the following statements is correct regarding sexually transmitted diseases (STDs)? (a) A person may contract syphilis by sharing milk with one already suffering from the disease. (b) Haemophilia is one of the STDs.(c) Genital herpes and sickle-cell anaemia are both STDs. (d) The chances of a 5-years boy contracting a STD are very little.

Description : Which one of the following statements is correct regarding sexually transmitted diseases (STDs)? (a) A person may contract syphilis by sharing milk with one already suffering from the disease. (b) Haemophilia is ... both STDs. (d) The chances of a 5-years boy contracting a STD are very little.

Last Answer : (d) The chances of a 5-years boy contracting a STD are very little.

Sickle cell disease is inherited due to defective copies of _________gene. a. Heparin b. Haemoglobin c. Creatinine d. Fibrinogen

Description : Sickle cell disease is inherited due to defective copies of _________gene. a. Heparin b. Haemoglobin c. Creatinine d. Fibrinogen

Last Answer : b. Haemoglobin

What purpose does FeCl3 serve in the electrophilic aromatic substitution reaction between chlorine and benzene? (a) It serves as a radical initiator to produce the chlorine radical needed to propagate the chain reaction. (b) It functions by destabilizing the carbocationic intermediate and thereby increases the rate of H+ loss. (c) It serves as a Lewis base catalyst by reacting with Cl2 to generate chloride ions. (d) It serves as a Lewis acid catalyst by reacting with the Cl2 and thereby activates it toward attack by benzene’s π electrons.

Description : What purpose does FeCl3 serve in the electrophilic aromatic substitution reaction between chlorine and benzene? (a) It serves as a radical initiator to produce the chlorine radical needed to propagate the ... by reacting with the Cl2 and thereby activates it toward attack by benzene's π electrons.

Last Answer : It serves as a Lewis acid catalyst by reacting with the Cl2 and thereby activates it toward attack by benzene’s π electrons.

Which one of the following could NOT cause a change in the mRNA ―reading frame‖? a. Insertion Sequence b. Base-Pair Substitution c. Base Addition d. Base Deletion

Description : Which one of the following could NOT cause a change in the mRNA ―reading frame‖? a. Insertion Sequence b. Base-Pair Substitution c. Base Addition d. Base Deletion

Last Answer : b. Base-Pair Substitution

Examination of blood of a person suspected of having anaemia shows large, immature, nucleated erythrocytes without haemoglobin. Supplementing his diet with which of the following is likely to alleviate his symptoms? (a) Iron compounds (b) Thiamine (c) Folic acid and cobalamine (d) Riboflavin

Description : Examination of blood of a person suspected of having anaemia shows large, immature, nucleated erythrocytes without haemoglobin. Supplementing his diet with which of the following is likely to alleviate his symptoms? (a) Iron compounds (b) Thiamine (c) Folic acid and cobalamine (d) Riboflavin

Last Answer : (c) Folic acid and cobalamine

In iron deficiency anaemia, the following is decreased: a. MCV (mean cell volume) b. ferritin c. MCH (mean cell haemoglobin) d. all above

Description : In iron deficiency anaemia, the following is decreased: a. MCV (mean cell volume) b. ferritin c. MCH (mean cell haemoglobin) d. all above

Last Answer : all above

In autosomal recessive inheritance: a. the rarer the trait the higher the possibility of marriages within the same family b. most recessive gene defects cause problem through failure to produce functional protein c. both males and females are affected equally severely d. all above

Description : In autosomal recessive inheritance: a. the rarer the trait the higher the possibility of marriages within the same family b. most recessive gene defects cause problem through failure to produce functional protein c. both males and females are affected equally severely d. all above

Last Answer : all above

If a male who is heterozygous for an autosomal trait mates with a female who is also heterozygous for that trait, what percent of their offspring are likely to be heterozygous for this trait as well?

Description : If a male who is heterozygous for an autosomal trait mates with a female who is also heterozygous for that trait, what percent of their offspring are likely to be heterozygous for this trait as well?

Last Answer : ANSWER: 50%

People who have migrated from the planes to an area adjoining Rohtang Pass about six months back (a) have more RBCs and their haemoglobin has a lower binding affinity to O2 (b) are not physically fit to play games like football (c) suffer from altitude sickness with symptoms like nausea, fatigue, etc. (d) have the usual RBC count but their haemoglobin has very high binding affinity to O2

Description : People who have migrated from the planes to an area adjoining Rohtang Pass about six months back (a) have more RBCs and their haemoglobin has a lower binding affinity to O2 (b) are not physically fit ... etc. (d) have the usual RBC count but their haemoglobin has very high binding affinity to O2

Last Answer : (a) have more RBCs and their haemoglobin has a lower binding affinity to O2

76. People who have migrated from the planes to an area adjoining Rohtang Pass about six months back (1) Have the usual RBC count but their haemoglobin has very high binding affinuty of O2 (2) Have more RBCs and their haemoglobin has a lower binding affinity of O2 (3) Are not physically fit to play games like football (4) Suffer from altitude sickness with symptoms like nausea, fatigue, etc

Description : 76. People who have migrated from the planes to an area adjoining Rohtang Pass about six months back (1) Have the usual RBC count but their haemoglobin has very high binding affinuty of O2 (2 ... to play games like football (4) Suffer from altitude sickness with symptoms like nausea, fatigue, etc

Last Answer : Have more RBCs and their haemoglobin has a lower binding affinity of O2

Which of the following diseases is a chronic, progressive, hereditary disease of the nervous system that results in progressive involuntary dance-like movement and dementia? a) Huntington’s disease Because it is transmitted as an autosomal dominant genetic disorder, each child of a parent with HD has a 50% risk of inheriting the illness.

Description : Which of the following diseases is a chronic, progressive, hereditary disease of the nervous system that results in progressive involuntary dance-like movement and dementia? a) Huntington's ... the central nervous system characterized by spongiform degeneration of the gray matter of the brain.

Last Answer : a) Huntington’s disease Because it is transmitted as an autosomal dominant genetic disorder, each child of a parent with HD has a 50% risk of inheriting the illness.

what if the father has sickle trait, does that mean the baby will have it?

Description : what if the father has sickle trait, does that mean the baby will have it?

Last Answer : If one parent has sickle cell trait and the other parent has the normal type of hemoglobin, there is a 50% (1 in 2) chance with EACH pregnancy that the baby will be born with sickle cell trait.

$ Sicke cell anaemia is a type of pleiotropy. ! Sex linked inharitance is also called criss cross inheritance.

Description : $ Sicke cell anaemia is a type of pleiotropy. ! Sex linked inharitance is also called criss cross inheritance.

Last Answer : $ Sicke cell anaemia is a type of pleiotropy. ! Sex linked inharitance is also called criss cross inheritance ... wrong D. If both As and R are wrong.