Sickle cell anaemia induce to
(a) change of amino acid in a-chain of haemoglobin
(b) change of amino acid in b-chain of haemoglobin
(c) change of amino acid in both a and b chains of
haemoglobin
(d) change of amino acid either a or b chains of
haemoglobin.

1 Answer

Answer :

(b) change of amino acid in b-chain of haemoglobin

Related questions

Description : . Sickle-cell anaemia is (a) caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin (b) caused by a change in a single base pair of DNA (c) characterized by elongated sickle like RBCs with a nucleus (d) an autosomal linked dominant trait.

Last Answer : (b) caused by a change in a single base pair of DNA

Description : Abnormal chain of amino acids in sickle cell anaemia is (A) Alpha chain (B) Beta chain (C) Delta chain (D) Gama chain

Last Answer : Answer : B

Description : Abnormal chain of amino acids in sickle cells anaemia is (A) Alpha chain (B) Beta chain (C) Gama chain (D) Delta chain

Last Answer : Answer : B

Description : Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement. (a) Both are due to a quantitative defect in globin chain synthesis. (b ... problem of globin molecules. (d) Both are due to a qualitative defect in globin chain synthesis.

Last Answer : (b) Thalassemia is due to less synthesis of globin molecules

Description : Haemoglobin SC disease: a. is common amongst Afro-carribean people b. does not show sickle cells in the blood film. c. causes severe anaemia d. causes retinal vein occlusion

Last Answer : causes retinal vein occlusion

Description : Both sickle cell anaemia and Huntington’s chorea are (a) virus-related diseases (b) bacteria-related diseases (c) congenital disorders (d) pollutant-induced disorders.

Last Answer : c) congenital disorders

Description : Which one of the following statements is correct regarding sexually transmitted diseases (STDs)? (a) A person may contract syphilis by sharing milk with one already suffering from the disease. (b) Haemophilia is ... both STDs. (d) The chances of a 5-years boy contracting a STD are very little.

Last Answer : (d) The chances of a 5-years boy contracting a STD are very little.

Description : Which of the following statements concerning abnormalities of the haemoglobin molecule is true? 1) Alpha thalassaemia is due to a deficiency of beta-chain production 2) HbS is caused by a ... is an adverse prognostic sign 5) oliguneoclitide probes may assist in the diagnosis of haemoglobinopathies

Last Answer : Answers-2 Alpha Thalassaemia is due to abnormalities of the alpha chain. Persistence of HbF has survival advnatages in severely affected subjects. C-alpha 16, beta 11. e-Hb electrophoresis(Dr Shu Ho)

Description : Blood cancer is commonly known as – (1) Leucoderma (2) Leukaemia (3) Haemophilia (4) Sickle-cell. anaemia

Last Answer : (2) Leukaemia Explanation: Leukemia is a cancer of blood and bone marrow. When a person has leukemia, the body makes too many white blood cells (leukocytes). The causes of most types of leukemia are not known. In general, all cancers have a breakdown in the normal way cell division is controlled.

Description : The oxygen dissociation curve is shifted to the right with: a. polycythaemia b. pyrexia c. respiratory acidosis d. sickle cell anaemia

Last Answer : pyrexia

Description : Which of the following is a correct match? (a) Down’s syndrome - 21st chromosome (b) Sickle cell anaemia - X-chromosome (c) Haemophilia - Y-chromosome (d) Parkinson’s disease - X and Y chromosome

Last Answer : a) Down’s syndrome - 21st chromosome

Description : .Which one of the following conditions though harmful in itself, is also potential saviour from a mosquito borne infectious disease ? (a) Thalassaemia (b) Sickle cell anaemia (c) Pernicious anaemia (d) Leukaemia

Last Answer : (b) Sickle cell anaemia

Description : Sickle cell anaemia has not been eliminated from the African population because (a) it is controlled by dominant genes (b) it is controlled by recessive genes (c) it is not a fatal disease (d) it provides immunity against malaria

Last Answer : (d) it provides immunity against malaria.

Description : .Represented here is the inheritance pattern of a certain type of trait in humans. Which one of the following conditions could be an example of this pattern? (a) Phenylketonuria (b) Sickle cell anaemia (c) Haemophilia (d) Thalassemia

Last Answer : (c) Haemophilia

Description : Pick out the correct statements. (1) Haemophilia is a sex-linked recessive disease. (2) Down's syndrome is due to aneuploidy. (3) Phenylketonuria is an autosomal recessive gene disorder. (4) Sickle cell anaemia is an X- ... are correct. (c) (1) and (4) are correct. (d) (2) and (4) are correct.

Last Answer : (b) (1), (2) and (3) are correct.

Description : .A disease caused by an autosomal primary non- disjunction is (a) Klinefelter’s syndrome (b) Turner’s syndrome (c) Sickle cell anaemia (d) Down’s syndrome.

Last Answer : (d) Down’s syndrome.

Description : Select the correct match. (a) Haemophilia – Y linked (b) Phenylketonuria – Autosomal dominant trait (c) Sickle cell anaemia – Autosomal recessive trait,chromosome -11 (d) Thalassemia – X linked

Last Answer : (c) Sickle cell anaemia – Autosomal recessive trait,chromosome -11

Description : The most striking example of point mutation is found in a disease called (a) Down’s syndrome (b) sickle cell anaemia (c) thalassaemia (d) night blindness.

Last Answer : (b) sickle cell anaemia

Description : Which of the following is an example of pleiotropy? (a) Haemophilia (b) Thalassemia (c) Sickle cell anaemia (d) Colour blindness

Last Answer : (c) Sickle cell anaemia

Description : A polygenic inheritance in human beings is (a) skin colour (b) phenylketonuria (c) colour blindness (d) sickle cell anaemia

Last Answer : (a) skin colour

Description : In human beings, multiple genes are involved in the inheritance of (a) sickle-cell anaemia (b) skin colour (c) colour blindness (d) phenylketonuria.

Last Answer : ) skin colour

Description : Multiple alleles control inheritance of (a) phenylketonuria (b) colour blindness (c) sickle cell anaemia (d) blood groups.

Last Answer : (d) blood groups.

Description : In thalassemia, an amino acid is substituted in (A) Alpha chain (B) Beta chain (C) Alpha and beta chains (D) Any chain MINERAL METABOLISM 195

Last Answer : Answer : D

Description : The primary structure of a protein refers to : (a) whether the protein is fibrous or globular (b) the amino acid sequence in the polypeptide chain (c) the orientation of the amino acid side chains in space (d) the presence or absence of an α-helix

Last Answer : the amino acid sequence in the polypeptide chain

Description : Sickle cell disease is inherited due to defective copies of _________gene. a. Heparin b. Haemoglobin c. Creatinine d. Fibrinogen

Last Answer : b. Haemoglobin

Description : Sickle cell anemia is caused a) When valine is replaced by glutamic acid in beta polypeptide chain b) When glutamic acid is replaced by valine in beta polypeptide chain c) When ... valine in alpha polypeptide chain d) When valine is replaced by glutamic acid in alpha polypeptide chain

Last Answer : b) When glutamic acid is replaced by valine in beta polypeptide chain

Description : Examination of blood of a person suspected of having anaemia shows large, immature, nucleated erythrocytes without haemoglobin. Supplementing his diet with which of the following is likely to alleviate his symptoms? (a) Iron compounds (b) Thiamine (c) Folic acid and cobalamine (d) Riboflavin

Last Answer : (c) Folic acid and cobalamine

Description : In iron deficiency anaemia, the following is decreased: a. MCV (mean cell volume) b. ferritin c. MCH (mean cell haemoglobin) d. all above

Last Answer : all above

Description : Which of the following is the quaternary structure of proteins concerned with? (a) sequence of amino acids in the peptide chain (b) description of the way the peptide chains are arranged with ... (c) location of the disulfide bridges in the peptide chain (d) conformation of the protein backbone

Last Answer : description of the way the peptide chains are arranged with respect to each other

Description : Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement : (1) Both are due to a quantitative defect in globin chain synthesis (2 ... problem of globin molecules (4) Both are due to a qualitative defect in globin chain synthesis

Last Answer : (2) Thalassemia is due to less synthesis of globin molecules

Description : Which statement about hormone types is correct? A) Non-steroid hormones activate an enzyme cascade. B) Steroid hormones regulate the production of a particular protein. C) Non-steroid hormones are ... all have four carbon rings with different side chains. E) All of the choices are correct.

Last Answer : E) All of the choices are correct.

Description : When haemoglobin takes up oxygen there is a change in the structure due to the moving closer together of (A) β-chains (B) β-chains (C) γ-chains (D) α and γ chains

Last Answer : Answer : A

Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Last Answer : C. Alter its folding or alignment of subunits

Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Last Answer : C. Alter its folding or alignment of subunits

Description : Abnormal chain of aminoacids in sickle cell anemia is (A) β-chain (B) β-chain (C) γ-chain (D) r-chain

Last Answer : Answer : B

Description : Foetal haemoglobin contains (A) Two α and two γ chains (B) Two β and two γ chains (C) Both (A) and (B) (D) None of these

Last Answer : Answer : A

Description : Examination of blood of a person suspected of having anaemia, shows large, immature, nucleated erythrocytes without haemoglobin. Supplementing his die

Last Answer : Examination of blood of a person suspected of having anaemia, shows large, immature, nucleated ... and cobalamine C. Riboflavin D. Iron compounds

Description : The concentration of which of the following decreases in anaemia? (1) Haemoglobin (2) Collagen (3) Hyoglobin (4) Myosin

Last Answer : (1) Haemoglobin Explanation: Anemia is a decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ... oxygen from the lungs to the capillaries, anemia leads to hypoxia (lack of oxygen) in organs.

Description : A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Last Answer : C. 0.5 – 1.0 g% per week

Description : Choose the correct statement about iron therapy: A. Haemoglobin response to intramuscular iron is faster than with oral iron therapy B. Iron must be given orally except in pernicious anaemia C. ... iron therapy must be given during pregnancy D. Infants on breastfeeding do not require medicinal iron

Last Answer : C. Prophylactic iron therapy must be given during pregnancy

Description : The concentration of which of the following decreases in anaemia ? (1) Haemoglobin(2) Collagen (3) Hyoglobin (4) Myosin

Last Answer : Haemoglobin

Description : Assertion `:` Most of the human haemoglobin in our body has `2 alph` and `2 beta` polypeptide chains. Reason `:` Haemoglobin is a conjugate protein an

Last Answer : Assertion `:` Most of the human haemoglobin in our body has `2 alph` and `2 beta` polypeptide ... False. D. If both Assertion & Reason are false.

Description : The number of polypeptide chains present in a molecule of haemoglobin is/are

Last Answer : The number of polypeptide chains present in a molecule of haemoglobin is/are A. 1 B. 3 C. 4 D. 2

Description : Nonsense codons bring about (A) Amino acid activation (B) Initiation of protein synthesis (C) Termination of protein synthesis (D) Elongation of polypeptide chains

Last Answer : Answer : C

Description : Bence-Jones proteins possess all the following properties except (A) They are dimers of light chains (B) Their amino acids sequences are identical (C) Their N-terminal halves have variable amino acid sequences (D) Their C-terminal halves have constant amino acid sequences

Last Answer : Answer : B

Description : Megaloblastic anaemia occurs in: A. Vitamin B12 but not folic acid deficiency B. Folic acid but not Vitamin B12 deficiency C. Either Vitamin B12 or folic acid deficiency D. Only combined Vitamin B12 + folic acid deficiency

Last Answer : C. Either Vitamin B12 or folic acid deficiency

Description : The carbon chains of prostanoic acid are bonded at the middle of the chain by a (A) 5-membered ring (B) 6-membered ring (C) 8-membered ring (D) None of these

Last Answer : Answer : B

Description : Haemoglobin is a/an (A) Amino acid (B) Biological catalyst (C) Protein (D) Enzyme

Last Answer : (C) Protein

Description : The true statement about solutions of amino acids at physiological pH is (A) All amino acids contain both positive and negative charges (B) All amino acids contain positively charged side chains ... amino acids contain only positive charge (D) All amino acids contain negatively charged side chains

Last Answer : Answer : A

Description : The true statement about solutions of amino acids at physiological pH is (A) All amino acids contain both positive and negative charges (B) All amino acids contain positively charged side chains ... amino acids contain only positive Charge (D) All amino acids contain negatively charged side chains

Last Answer : (A) All amino acids contain both positive and negative charges