Description : Hypoglycaemic coma can occur (A) In untreated diabetes mellitus (B) In starvation (C) After overdose of oral hypoglycaemic drugs (D) After overdose of insulin
Last Answer : Answer : D
Description : The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis
Last Answer : B
Description : An 16-year-old man presents with polyuria and polydipsia. Which of the following may confirm the diagnosis of diabetes mellitus? 1) A random plasma glucose of >7.5 mmol/L 2) A finding of 3+ ketonuria 3) An HbA1c of 7.0% 4) A fasting plasma glucose of 7.5 mmol/L 5) An abnormal glucose tolerance test
Last Answer : Answers-4 The diagnosis is usually relatively easy to confirm in a symptomatic subject. A random glucose of >11.1 mmol/L or a fasting glucose of >7.0 mmol/L would be regarded as ... haemoglobin (HbA1c) is also highly suggestive but not diagnostic. A glucose tolerance test is rarely needed.
Description : A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of ... serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations
Last Answer : Answers-2 a-An unusual but recognised feature particularly in children. However does not support a diagnosis of DKA. b-Suggests metabolic acidosis. c-'Normoglycaemic DKA' can occur and a glucose ... anorexia. e-Respiratory compensation leads to rapid deep (Kussmaul's) breathing. (Dr Mike Mulcahy)
Description : Which of the following condition is characterized by ketonuria but without glycosuria? (A) Diabetes mellitus (B) Diabetes insipidus (C) Prolonged starvation (D) Addison’s disease
Last Answer : Answer : C
Description : Presence of which of the following conditions in urine are indicative of diabetes mellitus? (a) Uremia and Ketonuria (b) Uremia and Renal Calculi (c) Ketonuria and Glycosuria (d) Renal calculi and Hyperglycaemia
Last Answer : (c) Ketonuria and Glycosuria
Description : Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89
Last Answer : Answer : A
Description : Obesity generally reflects excess intake of energy and is often associated with the development of (A) Nervousness (B) Non-insulin dependent diabetes mellitus (C) Hepatitis (D) Colon cancer
Last Answer : Answer : B
Description : Intensive insulin therapy: A. Prevents the aggressive development of atherosclerosis in diabetic patients. B. Is not associated with unawareness of hypoglycemia. C. Improves peripheral neuropathy. D. ... . E. Is indicated in all patients with non-insulin-dependent diabetes mellitus (NIDDM).
Last Answer : Answer: C DISCUSSION: Intensive insulin therapy is indicated in patients with IDDM who can actively participate in their own management and the attainment of the goals set for ... or prevents progression of these complications; however, better glucose control may improve peripheral neuropathy
Description : Which of the following conditions may be detectable by growth monitoring? 1) Hyperthyroidism 2) Hypothyroidism 3) Pseudohypoparathyroidism 4) XYY Syndrome 5) Insulin dependent diabetes mellitus
Last Answer : Answers-2
Description : Which of the following clinical characteristics is associated with Type 2 diabetes (previously referred to as non-insulin-dependent diabetes mellitus [NIDDM])? a) Can control blood glucose ... islet cell antibodies Individuals with Type 2 diabetes do not demonstrate islet cell antibodies.
Last Answer : a) Can control blood glucose through diet and exercise Oral hypoglycemic agents may improve blood glucose levels if dietary modification and exercise are unsuccessful.
Description : Which of the following clinical characteristics is associated with Type 1 diabetes (previously referred to as insulin-dependent diabetes mellitus [IDDM])? a) Presence of islet cell antibodies ... Requirement for oral hypoglycemic agents Individuals with Type 1 diabetes need insulin to preserve life.
Last Answer : a) Presence of islet cell antibodies Individuals with Type 1 diabetes often have islet cell antibodies.
Description : In diabetes mellitus, non-esterified fatty acid level in blood is increased, why?
Last Answer : Insulin inhibits hormone sensitive lipase, in diabetes, this inhibition is removed, so, more lipolysis is taking place.
Description : Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies
Description : The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation
Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis
Description : The level of free fatty acids in plasma is increased by (A) Insulin (B) Caffeine (C) Glucose (D) Niacin
Description : Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function
Description : 10. A person affected with phenyl ketonuria ,lack an enzyme that converts the amino acid Phenyl alanine into a) Valine b) Proline c) Tyrosine d) Methionine
Last Answer : 10.c) Tyrosine
Description : Glucose tolerance is decreased in (A) Diabetes mellitus (B) Hypopituitarisme (C) Addison’s disease (D) Hypothyroidism
Last Answer : A
Description : Specific gravity of urine is decreased in (A) Diabetes mellitus (B) Acute glomerulonephritis (C) Diarrhoea (D) Chronic glomerulonephritis
Description : Renal threshold for glucose is decreased in (A) Diabetes mellitus (B) Insulinoma (C) Renal glycosuria (D) Alimentary glycosuria
Last Answer : C
Description : Oedema can occur when (A) Plasma Na and Cl are decreased (B) Plasma Na and Cl are increased (C) Plasma proteins are decreased (D) Plasma proteins are increased
Description : A man suffering from diabetes mellitus drinks water more frequently as he has to eliminate from the blood extra (1) glucose (2) insulin (4) glucagon (4) salt
Last Answer : (1) glucose Explanation: The diabetic person has higher sugar in blood. Glucose is a form of sugar.
Description : Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency? (a) Luteinising - Failure of ovulation hormone (b) Insulin - Diabetes insipidus (c) Thyroxine - Tetany (d) Parathyroid - Diabetes mellitus hormone
Last Answer : (a) Luteinising - Failure of ovulation hormone
Description : Which one of the following pairs is incorrectly matched? (a) Glucagon – Beta cells (source) (b) Somatostatin – Delta cells (source) (c) Corpus luteum – Relaxin (secretion) (d) Insulin – Diabetes mellitus (disease
Last Answer : (a) Glucagon – Beta cells (source)
Description : Match the following hormones with their respective disease. (A) Insulin (i) Addison's disease (B) Thyroxin (ii) Diabetes insipidus (C) Corticoids (iii)Acromegaly (D) Growth hormone (iv) Goitre (v) Diabetes mellitus Select the correct option ... (iii) (c) (ii) (iv) (iii) (i) (d) (v) (iv) (i) (iii)
Last Answer : (d) (v) (iv) (i) (iii
Description : Which of the following statements is NOT true about diabetes mellitus? A) Type II diabetes is much more common than type I. B) Insulin injections are required in both type I and type II ... -sugar diet. E) Symptoms of diabetes include excessive thirst, frequent urination, and glucose in the urine.
Last Answer : B) Insulin injections are required in both type I and type II diabetes.
Description : The following feature disfavours use of oral hypoglycaemics in diabetes mellitus: A. Age at onset of disease over 40 years B. Insulin requirement more than 40 U/day C. Fasting blood sugar level between 100–200 mg/dl D. Associated obesity
Last Answer : B. Insulin requirement more than 40 U/day
Description : The present status of oral hypoglycaemics in diabetes mellitus is: A. They are the first choice drug in all cases B. They should be prescribed only if the patient refuses insulin injections C. ... I diabetes mellitus D. They are used first in most uncomplicated mild to moderate type 2 diabetics
Last Answer : D. They are used first in most uncomplicated mild to moderate type 2 diabetics
Description : The thiazolidinediones are mainly used as: A. Sole drug in type 1 diabetes mellitus B. Sole drug in type 2 diabetes mellitus C. Addon drug to a sulfonylurea and/or a biguanide in type 2 diabetes mellitus D. Addon drug to insulin in type 1 ... 18.34 1 8 . 3 4 B 18.35 1 8 . 3 5 D 18.36 1 8 . 3 6 C
Last Answer : C. Addon drug to a sulfonylurea and/or a biguanide in type 2 diabetes mellitus
Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above
Last Answer : D. All of the above
Description : Which of the following is not a sulfonylurea but acts by analogous mechanism to bring about quick and brief insulin release that is useful for normalizing meal time glycaemic excursions in type 2 diabetes mellitus: A. Glimepiride B. Miglitol C. Repaglinide D. Rosiglitazone
Last Answer : C. Repaglinide
Description : Insulin therapy is required for the following category/ categories of type 2 diabetes mellitus patients: A. Patients with ketoacidosis B. Patients undergoing surgery C. Pregnant diabetic D. All of the above
Description : Which of the following is not a specific indication for the more expensive monocomponent/human insulins: A. Insulin resistance B. Pregnant diabetic C. Sulfonylurea maintained diabetic posted for surgery D. Type 1 diabetes mellitus
Last Answer : D. Type 1 diabetes mellitus
Description : In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin
Last Answer : A. Prednisolone
Description : The essential fatty acids retard (A) Atherosclerosis (B) Diabetes mellitus (C) Nepritis (D) Oedema
Description : Glycocylated haemoglobin: a. is absent in the plasma of people without diabetes mellitus b. results from the combination of a HbA and a sugar c. when measured as HbA1c in plasma gives a more accurate retrospective estimates of blood sugar levels than other glycosylated products d. all above
Last Answer : all above
Description : Deficiency of magnesium may occur with (A) Alcoholism (B) Diabetes mellitus (C) Hypothyroidism (D) Advanced renal failure
Description : Oliguria can occur in (A) Diabetes mellitus (B) Diabetes insipidus (C) Acute glomerulonephritis (D) Chronic glomerulonephritis
Description : Polyuria can occur in (A) Diabetes mellitus (B) Diarrhoea (C) Acute glomerulonephritis (D) High fever
Description : Diabetes mellitus occur due to lack synthesis of hormon
Last Answer : Insuline
Description : Urinary water loss is increased in (A) Diabetes mellitus (B) Diabetes insipidus (C) Chronic glomerulonephritis (D) All of these
Description : Two conditions in which gluconeogenesis is increased are (A) Diabetes mellitus and atherosclerosis (B) Fed condition and thyrotoxicosis (C) Diabetes mellitus and Starvation (D) Alcohol intake and cigarette smoking
Description : Gluconeogenesis is increased in the following condition: (A) Diabetes insipidus (B) Diabetes Mellitus (C) Hypothyroidism (D) Liver diseases
Description : Glucose tolerance is increased in (A) Diabetes mellitus (B) Adrenalectomy (C) Acromegaly (D) Thyrotoxicosis
Description : Which of the following is/are not associated with increased likelihood of infection after major elective surgery? A. Age over 70 years. B. Chronic malnutrition. C. Controlled diabetes mellitus. D. Long-term steroid use. E. Infection at a remote body site.
Last Answer : Answer: C DISCUSSION: Controlled diabetes mellitus has been shown repeatedly not to be associated with increased likelihood of incisional infection provided one avoids operations on body parts ... site-are well-recognized adverse predictive factors and are identified in tables within the chapter
Description : Which of the following symptoms is NOT characteristic of diabetes mellitus? A) cells unable to take up glucose B) increased breakdown of fats and protein C) frequent urination D) sugar in the urine E) bronzing of the skin
Last Answer : E) bronzing of the skin
Description : Diabetes insipidus results from (A) Decreased insulin secretion (B) Decreased ADH secretion (C) Decreased aldosterone secretion (D) Unresponsiveness of osmoreceptors