Leukotrienes: 1) Are formed from the cyclooxygenase pathway 2) Are synthesized by fibroblasts 3) Decrease vascular permeability 4) Leukotriene D4 has been identified as SRS-A which causes bronchial wall smooth muscle relaxation 5) Stimulate mucus secretion

Leukotrienes: 1) Are formed from the cyclooxygenase pathway 2) Are synthesized by fibroblasts 3) Decrease vascular permeability 4) Leukotriene D4 has been identified as SRS-A which causes bronchial wall smooth muscle relaxation 5) Stimulate mucus secretion
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Answers-5 Leukotrienes are synthesized by leucocytes.They are mediators of allergic reaction. They increase vascular permeability and attract neutrophils and eosinophils to inflammatory sites. Leukotrienes are synthesised via the lipoxygenase pathway. Leukotriene D4 has been identified as SRS-A which causes bronchial wall and intestinal smooth muscle contraction (not dilatation). Leukotrienes also stimulate mucus production, an important consideration in the pathophysiology of bronchial asthma.
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Last Answer : Ans: B

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