With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the formation of red blood cell membranes. 3) Chylomicrons are synthesized in the liver. 4) HDL is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the formation of red blood cell membranes. 3) Chylomicrons are synthesized in the liver. 4) HDL is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.
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Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.
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With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the formation of red blood cell membranes. 3) Chylomicrons are synthesized in the liver. 4) HDL is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.

The lipoprotein richest in cholesterol is (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Description : The lipoprotein richest in cholesterol is (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Last Answer : Answer : C

The major source of cholesterol in arterial smooth muscle cells is from (A) IDL (B) LDL (C) HDL (D) Chylomicrons FATS AND FATTY ACID METABOLISM 101

Description : The major source of cholesterol in arterial smooth muscle cells is from (A) IDL (B) LDL (C) HDL (D) Chylomicrons FATS AND FATTY ACID METABOLISM 101

Last Answer : Answer : B

Cholesterol is transported from liver to extrahepatic tissues by (A) Chylomicrons (B) VLDL (C) HDL (D) LDL

Description : Cholesterol is transported from liver to extrahepatic tissues by (A) Chylomicrons (B) VLDL (C) HDL (D) LDL

Last Answer : Answer : D

This lipoprotein removes cholesterol from the body (A) HDL (B) VLDL (C) IDL (D) Chylomicrons

Description : This lipoprotein removes cholesterol from the body (A) HDL (B) VLDL (C) IDL (D) Chylomicrons

Last Answer : Answer : A

Triglycerides are transported from liver to extrahepatic tissues by (A) Chylomicrons (B) VLDL (C) HDL (D) LDL

Description : Triglycerides are transported from liver to extrahepatic tissues by (A) Chylomicrons (B) VLDL (C) HDL (D) LDL

Last Answer : Answer : B

Free fatty acids released from adipose tissue are transported in blood by (A) Albumin (B) VLDL (C) LDL (D) HDL

Description : Free fatty acids released from adipose tissue are transported in blood by (A) Albumin (B) VLDL (C) LDL (D) HDL

Last Answer : Answer : A

Apolipoprotiens C-I, C-II and C-III are present in all of the following except (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Description : Apolipoprotiens C-I, C-II and C-III are present in all of the following except (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Last Answer : Answer : C

Nascent HDL of intestinal origin acquires Apo C and Apo E from (A) Chylomicrons (B) VLDL (C) LDL (D) HDL of the hepatic origin

Description : Nascent HDL of intestinal origin acquires Apo C and Apo E from (A) Chylomicrons (B) VLDL (C) LDL (D) HDL of the hepatic origin

Last Answer : Answer : D

VLDL remnant may be converted into (A) VLDL (B) LDL (C) HDL (D) Chylomicrons

Description : VLDL remnant may be converted into (A) VLDL (B) LDL (C) HDL (D) Chylomicrons

Last Answer : Answer : C

Elevated plasma level of the following projects against atherosclerosis: (A) Chylomicrons (B) VLDL (C) HDL (D) LDL

Description : Elevated plasma level of the following projects against atherosclerosis: (A) Chylomicrons (B) VLDL (C) HDL (D) LDL

Last Answer : Answer : C

The highest phospholipids content is found in (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Description : The highest phospholipids content is found in (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Last Answer : Answer : D

Apolipoprotein B-48 is present in (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Description : Apolipoprotein B-48 is present in (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Last Answer : Answer : A

Apolipoproteins A-I and A-II are present in (A) LDL only (B) LDL and VLDL (C) HDL only (D) HDL and chylomicrons

Description : Apolipoproteins A-I and A-II are present in (A) LDL only (B) LDL and VLDL (C) HDL only (D) HDL and chylomicrons

Last Answer : Answer : D

Familial hypertriaacylglycerolemia is associated with (A) Over production of VLDL (B) Increased LDL concentration (C) Increased HDL concentration (D) Slow clearance of chylomicrons

Description : Familial hypertriaacylglycerolemia is associated with (A) Over production of VLDL (B) Increased LDL concentration (C) Increased HDL concentration (D) Slow clearance of chylomicrons

Last Answer : Answer : A

The lipoprotein with the fastest electrophoretic mobility and lowest TG content are (A) VLDL (B) LDL (C) HDL (D) Chylomicrones

Description : The lipoprotein with the fastest electrophoretic mobility and lowest TG content are (A) VLDL (B) LDL (C) HDL (D) Chylomicrones

Last Answer : Answer : C

A lipoprotein inversely related to the incidence of coronary artherosclerosis is (A) VLDL (B) IDL (C) LDL (D) HDL

Description : A lipoprotein inversely related to the incidence of coronary artherosclerosis is (A) VLDL (B) IDL (C) LDL (D) HDL

Last Answer : Answer : D

A lipoprotein associated with high incidence of coronary atherosclerosis is (A) LDL (B) VLDL (C) IDL (D) HDL

Description : A lipoprotein associated with high incidence of coronary atherosclerosis is (A) LDL (B) VLDL (C) IDL (D) HDL

Last Answer : Answer : A

The lipoprotein associated with activation of LCAT is (A) HDL (B) LDL (C) VLDL (D) IDL

Description : The lipoprotein associated with activation of LCAT is (A) HDL (B) LDL (C) VLDL (D) IDL

Last Answer : Answer : A

The following is true of simvastatin except: A. It is more potent than lovastatin B. At the highest recommended dose, it causes greater LDL-cholesterol lowering than lovastatin C. It does not undergo first pass metabolism in liver D. It can raise HDL-cholesterol level when the same is low at base line

Description : The following is true of simvastatin except: A. It is more potent than lovastatin B. At the highest recommended dose, it causes greater LDL-cholesterol lowering than lovastatin C. It does not undergo ... metabolism in liver D. It can raise HDL-cholesterol level when the same is low at base line

Last Answer : C. It does not undergo first pass metabolism in liver

HDL is synthesized in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine

Description : HDL is synthesized in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine

Last Answer : Answer : D

Which of the following lipoproteins would contribute to a measurement of plasma cholesterol in a normal individual following a 12 hr fast? (A) Chylomicrons (B) VLDL (C) Both VLDL and LDL (D) LDL

Description : Which of the following lipoproteins would contribute to a measurement of plasma cholesterol in a normal individual following a 12 hr fast? (A) Chylomicrons (B) VLDL (C) Both VLDL and LDL (D) LDL

Last Answer : Answer : D

The first lipoprotein to be secreted by the liver is (A) VLDL (B) nascent VLDL (C) LDL (D) IDL

Description : The first lipoprotein to be secreted by the liver is (A) VLDL (B) nascent VLDL (C) LDL (D) IDL

Last Answer : Answer : B

Activated lecithin cholesterol acyl transferase is essential for the conversion of (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2

Description : Activated lecithin cholesterol acyl transferase is essential for the conversion of (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2

Last Answer : Answer : B

Increased serum levels of which of the following may be associated with a decreased risk of atherosclerosis? (a) Very low-density lipoproteins (VLDL) (b) Low-density lipoproteins (LDL) (c) Intermediate – density lipoproteins (IDL) (d) High-density lipoproteins (HDL) (e) Cholesterol

Description : Increased serum levels of which of the following may be associated with a decreased risk of atherosclerosis? (a) Very low-density lipoproteins (VLDL) (b) Low-density lipoproteins (LDL) (c) Intermediate – density lipoproteins (IDL) (d) High-density lipoproteins (HDL) (e) Cholesterol

Last Answer : Ans: D

Which of the following is considered to be the best cholesterol? (1) VLDL (2) LDL (3) HDL (4) Triglycerids

Description : Which of the following is considered to be the best cholesterol? (1) VLDL (2) LDL (3) HDL (4) Triglycerids

Last Answer : (3) HDL Explanation: High-density lipoprotein (HDL) is one of the five major groups of lipoproteins, which, in order of sizes, largest to smallest, are chylomicrons, VLDL, IDL, LDL, and HDL, which ... heart attack. Low levels of HDL (less than 40 mg/dL) also increase the risk of heart disease.

Which of the following is considered to be the best cholesterol ? (1) VLDL (2) LDL (3) HDL (4) Triglycerids

Description : Which of the following is considered to be the best cholesterol ? (1) VLDL (2) LDL (3) HDL (4) Triglycerids

Last Answer : HDL

Correct ordering of lipoprotein molecules from lowest to the greater density is (A) LDL, IDL, VLDL, chylomicron (B) Chylomicron, VLDL, IDL, LDL (C) VLDL, IDL, LDL, chylomicron (D) LDL, VLDL, IDL, chylomicron

Description : Correct ordering of lipoprotein molecules from lowest to the greater density is (A) LDL, IDL, VLDL, chylomicron (B) Chylomicron, VLDL, IDL, LDL (C) VLDL, IDL, LDL, chylomicron (D) LDL, VLDL, IDL, chylomicron

Last Answer : Answer : B

Apolipoprotein B-100 is present in (A) Chylomicrons (B) VLDL only (C) LDL only (D) VLDL and LDL

Description : Apolipoprotein B-100 is present in (A) Chylomicrons (B) VLDL only (C) LDL only (D) VLDL and LDL

Last Answer : Answer : B

Apolipoproteins C-I, C-II and C-III are present in (A) Chylomicrons (B) VLDL (C) HDL (D) All of these

Description : Apolipoproteins C-I, C-II and C-III are present in (A) Chylomicrons (B) VLDL (C) HDL (D) All of these

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Increase in blood of this class of lipoproteins is beneficial to ward off coronary heart disease: (A) HDL (B) LDL (C) VLDL (D) IDL

Description : Increase in blood of this class of lipoproteins is beneficial to ward off coronary heart disease: (A) HDL (B) LDL (C) VLDL (D) IDL

Last Answer : Answer : A

The major source of extracellular cholesterol for human tissue is (A) Very low density lipoprotein (B) High density lipoprotein (C) Low density lipoprotein (D) Albumin

Description : The major source of extracellular cholesterol for human tissue is (A) Very low density lipoprotein (B) High density lipoprotein (C) Low density lipoprotein (D) Albumin

Last Answer : Answer : C

The lipoprotein with the fastest electrophoretic mobility and the lowest triglyceride content is (A) Chylomicron (B) VLDL (C) IDL (D) HDL

Description : The lipoprotein with the fastest electrophoretic mobility and the lowest triglyceride content is (A) Chylomicron (B) VLDL (C) IDL (D) HDL

Last Answer : Answer : D

Esterification of cholesterol occurs mainly in (A) Adipose tissue (B) Liver (C) Muscles (D) Kidneys

Description : Esterification of cholesterol occurs mainly in (A) Adipose tissue (B) Liver (C) Muscles (D) Kidneys

Last Answer : Answer : B

The majority of absorbed fat appears in the forms of (A) HDL (B) Chylomicrone (C) VLDL (D) LDL

Description : The majority of absorbed fat appears in the forms of (A) HDL (B) Chylomicrone (C) VLDL (D) LDL

Last Answer : Answer : B

Heparin releasable hepatic lipase converts (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2

Description : Heparin releasable hepatic lipase converts (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2

Last Answer : Answer : C

Dietary fats after absorption appear in the circulation as (A) HDL (B) VLDL (C) LDL (D) Chylomicron

Description : Dietary fats after absorption appear in the circulation as (A) HDL (B) VLDL (C) LDL (D) Chylomicron

Last Answer : Answer : D

Nascent chylomicron receives apolipoproteins C and E from (A) VLDL remnant (B) VLDL (C) LDL (D) HDL

Description : Nascent chylomicron receives apolipoproteins C and E from (A) VLDL remnant (B) VLDL (C) LDL (D) HDL

Last Answer : Answer : D

Total body mass is composed of an aqueous component and a nonaqueous component. The nonaqueous component is made up of which of the following? a. Liver b. Tendons c. Skeletal muscle d. Extracellular fluid e. Adipose tissue

Description : Total body mass is composed of an aqueous component and a nonaqueous component. The nonaqueous component is made up of which of the following? a. Liver b. Tendons c. Skeletal muscle d. Extracellular fluid e. Adipose tissue

Last Answer : Answer: b, e The nonaqueous portion of total body mass is made up of bones, tendons, and mineral mass as well as adipose tissue. The aqueous component contains the body cell ... and circulating blood cells. Also contributing to the aqueous portion is the interstitial fluid and intravascular volume

Which of the following is a characteristic feature of familial hypercholesterolaemia? 1) Autosomal dominant inheritance 2) elevated chylomicrons 3) hypertriglyceridaemia 4) increased expression of LDL receptors 5) Palmar xanthomas

Description : Which of the following is a characteristic feature of familial hypercholesterolaemia? 1) Autosomal dominant inheritance 2) elevated chylomicrons 3) hypertriglyceridaemia 4) increased expression of LDL receptors 5) Palmar xanthomas

Last Answer : Answers-1 Familial hypercholesterolaemia is an autosomal dominant condition manifest by increased LDL concentrations (not chylomicrons) due to constitutional abnormalities and reduced numbers of ... are characteristic and the condition is associated with a premature cardiovascular mortality.

Which of the following is a characteristic feature of familial hypercholesterolaemia? 1) Autosomal dominant inheritance 2) elevated chylomicrons 3) hypertriglyceridaemia 4) increased expression of LDL receptors 5) Palmar xanthomas

Description : Which of the following is a characteristic feature of familial hypercholesterolaemia? 1) Autosomal dominant inheritance 2) elevated chylomicrons 3) hypertriglyceridaemia 4) increased expression of LDL receptors 5) Palmar xanthomas

Last Answer : Answers-1 Familial hypercholesterolaemia is an autosomal dominant condition manifest by increased LDL concentrations (not chylomicrons) due to constitutional abnormalities and reduced numbers of ... are characteristic and the condition is associated with a premature cardiovascular mortality.

Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly (A) Taken up by liver (B) Taken up by extrahepatic tissues (C) Reutilised in adipose tissue (D) Excreted from the body FATS AND FATTY ACID METABOLISM 85

Description : Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly (A) Taken up by liver (B) Taken up by extrahepatic tissues (C) Reutilised in adipose tissue (D) Excreted from the body FATS AND FATTY ACID METABOLISM 85

Last Answer : Answer : A

Ketone bodies are synthesized in (A) Adipose tissue (B) Liver (C) Muscles (D) Brain

Description : Ketone bodies are synthesized in (A) Adipose tissue (B) Liver (C) Muscles (D) Brain

Last Answer : Answer : B

Apolipoprotein B-48 is synthesized in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine

Description : Apolipoprotein B-48 is synthesized in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine

Last Answer : Answer : C

The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Description : The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Last Answer : Answer : D

The rate limiting step in cholesterol biosynthesis is one of the followings : (A) LDL-receptor concentration (B) VLDL secretion (C) Mevalonic acid formation (D) Co-enzyme A formation

Description : The rate limiting step in cholesterol biosynthesis is one of the followings : (A) LDL-receptor concentration (B) VLDL secretion (C) Mevalonic acid formation (D) Co-enzyme A formation

Last Answer : (C) Mevalonic acid formation

Which one of the following statements is true regarding digestion and absorption of food in humans? (a) Fructose and amino acids are absorbed through intestinal mucosa with the help of carrier ions like Na+. (b) Chylomicrons are small lipoprotein particles that are transported from intestine into blood capillaries. (c) About 60% of starch is hydrolysed by salivary amylase in our mouth. (d) Oxyntic cells in our stomach secrete the proenzyme pepsinogen.

Description : Which one of the following statements is true regarding digestion and absorption of food in humans? (a) Fructose and amino acids are absorbed through intestinal mucosa with the help of carrier ions ... amylase in our mouth. (d) Oxyntic cells in our stomach secrete the proenzyme pepsinogen.

Last Answer : (a) Fructose and amino acids are absorbed through intestinal mucosa with the help of carrier ions like Na

The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level

Description : The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level

Last Answer : C. It increases the incidence of myopathy due to statins

Gemfibrozil has the following features except: A. It lowers plasma LDL cholesterol to a greater extent than triglycerides B. It tends to raise plasma HDL-cholesterol level C. It is a first line drug for type III, type IV and type V hyperlipoproteinemia D. It reduces the incidence of myocardial infarctio

Description : Gemfibrozil has the following features except: A. It lowers plasma LDL cholesterol to a greater extent than triglycerides B. It tends to raise plasma HDL-cholesterol level C. It is a first ... type III, type IV and type V hyperlipoproteinemia D. It reduces the incidence of myocardial infarctio

Last Answer : A. It lowers plasma LDL cholesterol to a greater extent than triglycerides