Description : Lactate formed in muscles can be utilised through (A) Rapoport-Luebeling cycle (B) Glucose-alanine cycle (C) Cori’s cycle (D) Citric acid cycle
Last Answer : C
Description : Which of the following intermediates of metabolism can be both a precursor and a product of glucose? (A) Lactate (B) Pyruvate (C) Alanine (D) Acetyl-CoA
Last Answer : Answer : A
Description : A reaction which may be considered an isomerisation is (A) Glucose 6-Phosphate fructose 6 phosphate (B) 3-Phosphoglycerate 2-phosphoglycerate (C) 2-phosphoglycerate phosphoenolpyruvate (D) Pyruvate Lactate
Description : Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate
Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte
Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate
Last Answer : B
Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate
Last Answer : A
Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate
Description : The number of ATP molecules required to convert 2 molecules of lactate into glucose in mammalian liver is (A) 2 (B) 4 (C) 5 (D) 6
Last Answer : Answer : D
Description : Glucose-6-phosphatase is absent or deficient in (A) Von Gierke’s disease (B) Pompe’s disease (C) Cori’s disease (D) McArdle’s disease
Description : Anion gap of plasma can be due to the presence of all the following except (A) Bicarbonate (B) Lactate (C) Pyruvate (D) Citrate
Description : Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase
Last Answer : Answer : C
Description : Phosphofructokinase is allosterically inhibited by (A) Fructose-1, 6-biphosphate (B) Lactate (C) Pyruvate (D) Citrate
Description : End product of aerobic glycolysis is (A) Acetyl CoA (B) Lactate (C) Pyruvate (D) CO2 and H2O
Description : Pyruvate dehydrogenase a multienzyme complex is required for the production of (A) Acetyl-CoA (B) Lactate (C) Phosphoenolpyruvate (D) Enolpyruvate
Description : Erythrocytes under normal conditions and microorganisms under anaerobic conditions may accumulate (A) NADPH (B) Pyruvate (C) Phosphoenolpyruvate (D) Lactate
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Last Answer : Answer : B
Description : Compared to the resting state, vigorously contracting muscle shows (A) An increased conversion of pyruvate to lactate (B) Decreased oxidation of pyruvate of CO2 and water (C) A decreased NADH/NAD+ ratio (D) Decreased concentration of AMP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 21
Description : When O2 supply is inadequate, pyruvate is converted to (A) Phosphopyruvate (B) Acetyl CoA (C) Lactate (D) Alanine
Description : In which condition pyruvate is produced, and when lactate?
Last Answer : In aerobic condition pyruvate is produced. When oxygen is lacking, lactate is produced.
Description : The process of breakdown of glycogen to glucose in the liver and pyruvate and lacate in the muscle is known as (A) Glyogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Cellular degradation
Description : In the normal resting state of human most of the blood glucose burnt as fuel is consumed by (A) Liver (B) Brain (C) Adipose tissue (D) Muscles
Description : Glucose-1-phosphate liberated from glycogen cannot be converted into free glucose in (A) Liver (B) Kidneys (C) Muscles (D) Brain
Description : Glucose-6-phosphatase is not present in (A) Liver and kidneys (B) Kidneys and muscles (C) Kidneys and adipose tissue (D) Muscles and adipose tissue
Last Answer : D
Description : Which of the following statements about delivery-dependent oxygen consumption are true? A. Below the critical oxygen delivery (D(overdot)O 2crit), one would expect to see a decrease in the ... oxygen extraction ratio remains constant as long as oxygen delivery remains above D(overdot)O 2crit.
Last Answer : Answer: BC DISCUSSION: Oxygen consumption is said to be delivery dependent below a critical point, D(overdot)O 2crit, at which anaerobic metabolism supervenes. Above this point, oxygen ... the therapeutic benefit of trying to achieve supranormal oxygen delivery has not been firmly established
Description : The main product of glycolysis under aerobic conditions is a. Pyruvate b. Lactate c. None of these d. Both a and b Ans: A 2. The protein moiety of an enzyme is known as a. Holo enzyme b. Apo enzyme c. Co enzyme d. Enzyme
Last Answer : Ans: B
Description : Rapoport-Luebering cycle is located in (A) Liver (B) Muscles (C) Brain (D) Erythrocytes
Description : Isoenzymes of lactate dehydrogenase are useful for the diagnosis of (A) Heart disease (B) Kidney disease (C) Liver disease (D) Both (A) and (C)
Description : Why lactate is transported from muscle to liver?
Last Answer : Oxygen is limited in muscle, so lactic acid could not be made to pyruvate in muscle. So, it is transported to liver, where it is made to pyruvate and then to glucose.
Description : Glucose cannot be synthesized from (A) Glycerol (B) Lactate (C) Alanine (D) Leucine
Description : In non shivering thermogenesis (A) Glucose is oxidized to lactate (B) Fatty acids uncouple oxidative phosphorylation (C) Ethanol is formed (D) ATP is burned for heat production
Description : Which one of the following compounds cannot give rise to the net synthesis of Glucose? (A) Lactate (B) Glycerol (C) α-ketoglutarate (D) Acetyl CoA
Description : Debranching enzyme is absent in (A) Cori’s disease (B) Andersen’s disease (C) Von Gierke’s disease (D) Her’s disease
Description : The following are true about the oxidation of glucose: a. glycolysis produces 3% of the energy ultimately obtained from glucose b. the first stage of glycolysis involves phosphorylation of glucose to 1,6-fructose biphosphate. c. glucose enters the Kreb's cycle as pyruvate d. all above
Last Answer : all above
Description : Glucose is to photosynthesis as pyruvate is to _____. a. Oxidative Phosphorylation b. Glycolysis c. Fermentation d. Citric Acid Cycle
Last Answer : a. Oxidative Phosphorylation
Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate
Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct
Last Answer : D. Both A and B are correct
Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase
Description : A regulator of the enzyme glucogen synthase is (A) Citric Acid (B) Pyruvate (C) Glucose-6-PO4 (D) GTP
Description : In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase
Description : Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible: (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1, 6 diphosphate to ... phosphate (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : Acetyl CoA formed from pyruvate can be used for the synthesis of all the following except (A) Glucose (B) Fatty acids (C) Cholesterol (D) Steroid hormones
Description : The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD
Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency
Description : In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase
Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Description : Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible. (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1,6-bisphosphate to fructose- ... (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : Two examples of substrate level phosphorylation in EM pathway of glucose metabolism are in the reactions of (A) 1,3 bisphosphoglycerate and phosphoenol pyruvate (B) Glucose-6 phosphate ... phosphate (C) 3 phosphoglyceraldehyde and phosphoenolpyruvate (D) 1,3 diphosphoglycerate and 2-phosphoglycerate
Description : The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatose (D) Glycerokinase
Description : The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatase (D) Glycerokinase