Description : Which of the following intermediates of metabolism can be both a precursor and a product of glucose? (A) Lactate (B) Pyruvate (C) Alanine (D) Acetyl-CoA
Last Answer : Answer : A
Description : End product of aerobic glycolysis is (A) Acetyl CoA (B) Lactate (C) Pyruvate (D) CO2 and H2O
Last Answer : Answer : C
Description : Pyruvate dehydrogenase a multienzyme complex is required for the production of (A) Acetyl-CoA (B) Lactate (C) Phosphoenolpyruvate (D) Enolpyruvate
Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate
Last Answer : A
Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate
Description : Pyruvate is converted into acetyl-CoA by (A) Decarboxylation (B) Dehydrogenation (C) Oxidative decarboxylation (D) Oxidative deamination
Description : Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible: (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1, 6 diphosphate to ... phosphate (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : While citrate is converted to isocitrate in the mitochondria, it is converted to _______ in the cytosol. (A) Acetyl CoA + oxaloacetate (B) Acetyl CoA + malonyl CoA (C) Acetyl CoA + Pyruvate (D) Acetyl CoA + acetoacetyl CoA
Description : Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible. (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1,6-bisphosphate to fructose- ... (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Last Answer : C
Description : Pyruvate is converted to acetyl CoA by which enzyme?
Last Answer : Pyruvate dehydrogenate.
Description : Which one of the following compounds cannot give rise to the net synthesis of Glucose? (A) Lactate (B) Glycerol (C) α-ketoglutarate (D) Acetyl CoA
Last Answer : B
Description : Thiamine is essential for (A) Pyruvate dehydrogenase (B) Isocitrate dehydrogenase (C) Succinate dehydrogenase (D) Acetyl CoA synthetase ENZYMES 165
Last Answer : Answer : B
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Last Answer : Answer : D
Description : Acetyl CoA required for de novo synthesis of fatty acids is obtained from (A) Breakdown of existing fatty acids (B) Ketone bodies (C) Acetate (D) Pyruvate
Description : An allosteric inhibitor of pyruvate dehydrogenase is (A) Acetyl CoA (B) ATP (C) NADH (D) Pyruvate
Description : Conversion of pyruvate into acetyl CoA is catalysed by (A) Pyruvate dehydrogenase (B) Didrolipoyl acetyl transferase (C) Dihydrolipoyl dehydrogenase (D) All the 3 acting in concert
Description : Acetyl-CoA can be formed from (A) Pyruvate (B) Fatty acids (C) ketone bodies (D) All of these
Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase
Description : Carboxylation of acetyl-CoA to malonylCoA requires the enzyme: (A) Acetyl-CoA carboxylase (B) Pyruvate carboxylase (C) Acetyl transacylase (D) Acyl CoA-synthetase
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate
Description : The coenzyme not involved in the formation of acetyl-CoA from pyruvate is (A) TPP (B) Biotin (C) NAD (D) FAD
Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase
Description : Fully activated pyruvate carboxylase depends upon the presence of (A) Malate and Niacin (B) Acetyl CoA and biotin (C) Acetyl CoA and thiamine pyrophosphate (D) Oxaloacetate and biotin
Description : Biotin is a coenzyme for (A) Pyruvate carboxylase (B) Acetyl CoA carboxylase (C) Propionyl CoA carboxylase (D) All of these
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : Acetyl CoA formed from pyruvate can be used for the synthesis of all the following except (A) Glucose (B) Fatty acids (C) Cholesterol (D) Steroid hormones
Description : The conversion of pyruvate to acetyl CoA and CO2 (A) Is reversible (B) Involves the participation of lipoic acid (C) Depends on the coenzyme biotin (D) Occurs in the cytosol
Description : Which of the following compound is a positive allosteric modifier of the enzyme pyruvate carboxylase? (A) Biotin (B) Acetyl CoA (C) Oxaloacetate (D) ATP
Description : Propionyl CoA formed oxidation of fatty acids having an odd number of carbon atoms is converted into (A) Acetyl CoA (B) Acetoacetyl CoA (C) D-Methylmalonyl CoA (D) Butyryl CoA
Description : Connecting link between glycolysis and Krebs’ cycle before pyruvate entering Krebs’ cycle is changed to (a) oxaloacetate (b) PEP (c) pyruvate (d) acetyl CoA.
Last Answer : (d) acetyl CoA.
Description : If oxygen is present pyruvate will be converted to acetyl enter the mitochondria and?
Last Answer : Need answer
Description : Glucose cannot be synthesized from (A) Glycerol (B) Lactate (C) Alanine (D) Leucine
Description : Lactate formed in muscles can be utilised through (A) Rapoport-Luebeling cycle (B) Glucose-alanine cycle (C) Cori’s cycle (D) Citric acid cycle
Description : Anion gap of plasma can be due to the presence of all the following except (A) Bicarbonate (B) Lactate (C) Pyruvate (D) Citrate
Description : Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase
Description : Phosphofructokinase is allosterically inhibited by (A) Fructose-1, 6-biphosphate (B) Lactate (C) Pyruvate (D) Citrate
Description : A reaction which may be considered an isomerisation is (A) Glucose 6-Phosphate fructose 6 phosphate (B) 3-Phosphoglycerate 2-phosphoglycerate (C) 2-phosphoglycerate phosphoenolpyruvate (D) Pyruvate Lactate
Description : Erythrocytes under normal conditions and microorganisms under anaerobic conditions may accumulate (A) NADPH (B) Pyruvate (C) Phosphoenolpyruvate (D) Lactate
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Description : Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate
Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte
Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate
Description : Compared to the resting state, vigorously contracting muscle shows (A) An increased conversion of pyruvate to lactate (B) Decreased oxidation of pyruvate of CO2 and water (C) A decreased NADH/NAD+ ratio (D) Decreased concentration of AMP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 21
Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate
Description : Cori’s cycle transfers (A) Glucose from muscles to liver (B) Lactate from muscles to liver (C) Lactate from liver to muscles (D) Pyruvate from liver to muscles
Description : In which condition pyruvate is produced, and when lactate?
Last Answer : In aerobic condition pyruvate is produced. When oxygen is lacking, lactate is produced.
Description : All of the following are required for synthesis of alanine except (A) Pyruvate (B) α-ketoglutarate (C) Glutamate (D) Pyridoxal phosphate
Description : Alanine can be synthesized from (A) Glutamate and α-ketoglutarate (B) Pyruvate and glutamate (C) Pyruvate and α-ketoglutarate (D) Asparate and α-ketoglutarate
Description : Heme is synthesized from (A) Succinyl-CoA and glycine (B) Active acetate and glycine (C) Active succinate and alanine (D) Active acetate and alanine