Description : The apolipoprotein which acts as actiator of extrahepatic lipoprotein is (A) Apo-A (B) Apo-B (C) Apo-C (D) Apo-D
Last Answer : Answer : C
Description : LCAT is (A) Lactose choline alamine transferse (B) Lecithin cholesterol acyl transferase (C) Lecithin carnitine acyl transferase (D) Lanoleate carbamoyl acyl transferase
Last Answer : Answer : B
Description : Activated lecithin cholesterol acyl transferase is essential for the conversion of (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2
Description : Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipase A2 (D) Lipoprotein lipase
Description : The apolipoprotein which acts as activator of LCAT is (A) A-I (B) A-IV (C) C-II (D) D
Last Answer : Answer : A
Description : Apolipoprotein A-I acts as (A) Enzyme activator (B) Ligand for receptor (C) Both (A) and (B) (D) None of these
Description : Phospholipase A2 is an enzyme which removes a fatty acid residue from lecithin to form (A) Lecithin fragments (B) Phosphotidic acid (C) Glyceryl phosphate (D) Lysolecithin
Last Answer : Answer : D
Description : Lysolecithin is formed from lecithin by the action of (A) Phospholipase A1 (B) Phospholipase A2 (C) Phospholipase C (D) Phospholipase D
Description : Ketone bodies serve as a fuel for (A) Extrahepatic tissues (B) Hepatic tissues (C) Erythrocytes (D) Mitochondria
Description : Zellweger’s syndrome is due to inherited absence of (A) Peroxisomes (B) Phospholipase A1 (C) Acyl-Co-A dehydrogenase (D) Thiolase
Description : An important zinc containing enzyme is (A) Carboxypeptidase A (B) Isocitrate dehydrogenase (C) Cholinesterate (D) Lipoprotein lipase
Description : ‘Clearing factor’ is (A) Lipoprotein lipase (B) Crotonase (C) 7-dehydro cholesterol (D) β-sitosterol
Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase
Description : A non-functional plasma enzyme is (A) Psudocholinesterase (B) Lipoprotein lipase (C) Proenzyme of blood coagulation (D) Lipase
Description : An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase
Description : This interferes with cholesterol absorption (A) Lipoprotein lipase (B) Creatinase (C) 7-dehydrocholesterol (D) β-sitosterol
Description : The triacyl glycerol present in plasma lipoproteins are hydrolyzed by (A) Linqual lipase (B) Pancreatic lipase (C) Colipase (D) Lipoprotein lipase
Description : Genetic deficiency of lipoprotein lipase causes hyperlipoproteinaemia of following type: (A) Type I (B) Type IIa (C) Type IIb (D) Type V
Description : Lipoprotein lipase deficiency is associated with: 1) Abetalipoproteinaemia 2) Combined hyperlipidaemia 3) Familial combined hyperlipidaemia 4) Familial Hypercholesterolaemia 5) Marked Hypertriglyceridaemia
Last Answer : Answers-5 Lipoprotein lipase deficiency is autosomal recessive and associated with increased chylomicrons and marked hypertriglyceridaemia.
Description : Erythromycin binds to 50 S ribosomal sub unit and (A) Inhibits binding of amino acyl tRNA (B) Inhibits Peptidyl transferase activity (C) Inhibits translocation (D) Causes premature chain termination
Description : Peptidyl transferase activity is present in (A) 40 S ribosomal subunit (B) 60 S ribosomal subunit (C) eEF-2 (D) Amino acyl tRNA
Description : The α-amino group of the new amino acyl tRNA in the A site carries out a nucleophilic attack on the esterified carboxyl group of the peptidyl tRNA occupying the P site. This reaction is catalysed by (A) DNA polymerase (B) RNA polymerase (C) Peptidyl transferase (D) DNA ligase
Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity
Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex
Description : Synthesis of polyunsaturated fatty acids involves the enzyme systems: (A) Acyl transferase and hydratase (B) Desaturase and elongase (C) Ketoacyl-CoA reductase and hydratase (D) Dihydroxyacetone phosphate
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in inflammatory processes are produced from arachidonic acid by (a) ... 2 (c) Glutathione - S - transferase (d) Lipoxygenase (e) Phospholipase A2
Last Answer : Ans: B
Description : Heparin releasable hepatic lipase converts (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2
Description : A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the ... is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs
Last Answer : Answer: a, b, c, d, e Tumor cachexia appears to be mediated by TNFa. Lipopolysaccharide (LPS), as well as other cytokines, activate a variety of inflammatory cells, most ... chronic syndromes of anorexia, weight loss, and cachexia that are associated with both chronic infection and malignancy
Description : Six months after beginning atorvastatin, the patient's total and LDL cholesterol concentrations remained above normal and he continued to have anginal attacks despite good adherence to his antianginal ... Increased endocytosis of HDL by the liver (e) Increased lipid hydrolysis by lipoprotein lipase
Last Answer : Ans: C
Description : The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level
Last Answer : C. It increases the incidence of myopathy due to statins
Description : Choose the correct statement(s) about actions of insulin: A. It favours translocation of glucose transporters from intracellular site to the plasma membrane B. It enhances transcription of lipoprotein ... vascular endothelium C. It increases production of the enzyme glucokinase D. All of the above
Last Answer : D. All of the above
Description : The most significant nursing problem related to continuous tube feedings is a) potential for aspiration Because the normal swallowing mechanism is bypassed, consideration of the danger of ... in fat metabolism and lipoprotein synthesis Tube feedings maintain fat metabolism and lipoprotein synthesis.
Last Answer : a) potential for aspiration Because the normal swallowing mechanism is bypassed, consideration of the danger of aspiration must be foremost in the mind of the nurse caring for the patient receiving continuous tube feedings.
Description : Which of the following can be used as a source of energy in extrahepatic tissues? (A) Acetoacetate (B) Acetone (C) Both (A) and (B) (D) None of these
Description : Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly (A) Taken up by liver (B) Taken up by extrahepatic tissues (C) Reutilised in adipose tissue (D) Excreted from the body FATS AND FATTY ACID METABOLISM 85
Description : Cholesterol is transported from liver to extrahepatic tissues by (A) Chylomicrons (B) VLDL (C) HDL (D) LDL
Description : Triglycerides are transported from liver to extrahepatic tissues by (A) Chylomicrons (B) VLDL (C) HDL (D) LDL
Description : Fecal urobilinogen is increased in (A) Hemolytic jaundice (B) Obstruction of biliary duct (C) Extrahepatic gall stones (D) Enlarged lymphnodes
Description : Apolipoprotein B-100 is present in (A) Chylomicrons (B) VLDL only (C) LDL only (D) VLDL and LDL
Description : Apolipoprotein B-48 is present in (A) Chylomicrons (B) VLDL (C) LDL (D) HDL
Description : Apolipoprotein B-48 is synthesized in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine
Description : Apolipoprotein B-100 is synthesised in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine
Description : The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL
Description : The apolipoprotein which acts as ligand for LDL receptor is (A) B-48 (B) B-100 (C) A (D) C
Description : The apolipoprotein which from the integral component of VLDL is (A) B-100 (B) B-48 (C) A (D) D
Description : The apolipoprotein which forms the integral component of chylomicron is (A) B-100 (B) B-48 (C) C (D) D
Description : The newly entering amino acyl tRNA into A site requires (A) EF-II (B) Ribosomal RNA (C) mRNA (D) EF-I
Description : In the process of elongation of chain binding of amino acyl tRNA to the A site requires (A) A proper codon recognition (B) GTP (C) EF-II (D) GDP
Description : When choline of lecithin is replaced by ethanolamine, the product is (A) Spingomyelin (B) Cephalin (C) Plasmalogens (D) Lysolecithin