Creatinine clearance is deceased in (A) Acute tubular necrosis (B) Acute glomerulonephritis (C) Hypertension (D) Myopathies

Creatinine clearance is deceased in (A) Acute tubular necrosis (B) Acute glomerulonephritis (C) Hypertension (D) Myopathies
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Filtration fraction is increased in (A) Acute glomerulonephritis (B) Chronic glomerulonephritis (C) Hypertension (D) Hypotension

Description : Filtration fraction is increased in (A) Acute glomerulonephritis (B) Chronic glomerulonephritis (C) Hypertension (D) Hypotension

Last Answer : Answer : A

The filtration factor is increased in (A) Glomerulonephritis (B) Malignant phase of hypertension (C) Early essential hypertension (D) Acute nephritis

Description : The filtration factor is increased in (A) Glomerulonephritis (B) Malignant phase of hypertension (C) Early essential hypertension (D) Acute nephritis

Last Answer : Answer : B

The filtration factor tends to be normal in (A) Early essential hypertension (B) Malignant phase of hypertension (C) Glomerulonephritis (D) Acute nephritis

Description : The filtration factor tends to be normal in (A) Early essential hypertension (B) Malignant phase of hypertension (C) Glomerulonephritis (D) Acute nephritis

Last Answer : Answer : A

Creatinine EDTA clearance is a test to measure (A) Renal plasma flow (B) Filtration fraction (C) Glomerular filtration rate (D) Tubular function

Description : Creatinine EDTA clearance is a test to measure (A) Renal plasma flow (B) Filtration fraction (C) Glomerular filtration rate (D) Tubular function

Last Answer : Answer : C

Among the following, a test of tubular function is (A) Creatinine clearance (B) Inulin clearance (C) PAH clearance (D) PSP excretion test

Description : Among the following, a test of tubular function is (A) Creatinine clearance (B) Inulin clearance (C) PAH clearance (D) PSP excretion test

Last Answer : Answer : D

Acute tubular necrosis?

Description : Acute tubular necrosis?

Last Answer : DefinitionAcute tubular necrosis is a kidney disorder involving damage to the tubule cells of the kidneys, resulting in acute kidney failure.Alternative NamesNecrosis - renal tubular; ATN; ... reactionInjury or trauma that damages the musclesRecent major surgerySeptic shock or other forms of shockS

Which of the following statement(s) is/are true concerning the outcome in patients with acute renal failure? a. Mortality for ischemic acute tubular necrosis without other organ failure is approximately 6% b. Multiple organ failure complicated with acute renal failure is associated with mortality ranging from 50% to 90% c. Recovery of renal function after six weeks is unlikely d. There is no difference in survival between oliguric and nonoliguric renal failure

Description : Which of the following statement(s) is/are true concerning the outcome in patients with acute renal failure? a. Mortality for ischemic acute tubular necrosis without other organ failure is ... is unlikely d. There is no difference in survival between oliguric and nonoliguric renal failure

Last Answer : Answer: a, b, c Survival of patients with acute renal failure is a function of the successful treatment of the primary disease from which the renal failure was derived. The mortality ... is unlikely. Nonoliguric renal failure is usually limited in its extent and is almost always reversible

Which of the following statement(s) is/are true concerning the effects of MOFS? a. Pulmonary dysfunction tends to arise early and may resolve within 7 to 10 days b. Unless the precipitating insult has prompted oliguric acute tubular necrosis, renal function tends to be maintained early in the course of MOFS c. Although hepatic dysfunction is common with MOFS, the GI tract plays little role in this process d. Intercurrent nosocomial infection, most commonly pulmonary, is a common complication providing a “second hit” to the patient

Description : Which of the following statement(s) is/are true concerning the effects of MOFS? a. Pulmonary dysfunction tends to arise early and may resolve within 7 to 10 days b. Unless the precipitating ... infection, most commonly pulmonary, is a common complication providing a second hit to the patient

Last Answer : Answer: a, b, d Pulmonary dysfunction typically arises early in the development of systemic inflammation and may represent mild relatively localized acute lung injury or it may be a prelude ... is marked by progressive rise in serum bilirubin levels after a latent period of several days

Acute renal failure (ARF) may be caused by all of the following except (a) Acute tubular necrosis (ATN) due to drug therapy (e.g., aminoglycosides, contrast media) (b) Severe hypotension or circulatolry collapse (c) Decreased cardiac output, as from congestive heart failure (d) Hemolysis, myoglobinuria (e) Hyperkalemia

Description : Acute renal failure (ARF) may be caused by all of the following except (a) Acute tubular necrosis (ATN) due to drug therapy (e.g., aminoglycosides, contrast media) (b) Severe hypotension ... (c) Decreased cardiac output, as from congestive heart failure (d) Hemolysis, myoglobinuria (e) Hyperkalemia

Last Answer : Ans: E

Urea clearance is lowered in (A) Acute nephritis (B) Pneumonia (C) Early stage of nephritic syndrome (D) Benign hypertension

Description : Urea clearance is lowered in (A) Acute nephritis (B) Pneumonia (C) Early stage of nephritic syndrome (D) Benign hypertension

Last Answer : Answer : A

The filtration factor is decreased in (A) Glomerulonephritis (B) Early essential hypertension (C) Malignant phase of hypertension (D) Starvation

Description : The filtration factor is decreased in (A) Glomerulonephritis (B) Early essential hypertension (C) Malignant phase of hypertension (D) Starvation

Last Answer : Answer : A

A simple way to assess tubular function is to withhold food and water for 12 hours and, then, measure (A) Serum urea (B) Serum creatinine (C) Urine output in one hour (D) Specific gravity of urine

Description : A simple way to assess tubular function is to withhold food and water for 12 hours and, then, measure (A) Serum urea (B) Serum creatinine (C) Urine output in one hour (D) Specific gravity of urine

Last Answer : Answer : D

Oliguria can occur in (A) Diabetes mellitus (B) Diabetes insipidus (C) Acute glomerulonephritis (D) Chronic glomerulonephritis

Description : Oliguria can occur in (A) Diabetes mellitus (B) Diabetes insipidus (C) Acute glomerulonephritis (D) Chronic glomerulonephritis

Last Answer : Answer : A

Haematuria can occur in all of the following except (A) Acute glomerulonephritis (B) Cancer of urinary tract (C) Stone in urinary tract (D) Mismatched blood transfusion

Description : Haematuria can occur in all of the following except (A) Acute glomerulonephritis (B) Cancer of urinary tract (C) Stone in urinary tract (D) Mismatched blood transfusion

Last Answer : Answer : D

Heavy proteinuria occurs in (A) Acute glomerulonephritis (B) Acute pyelonephritis (C) Nephrosclerosis (D) Nephrotic syndrome

Description : Heavy proteinuria occurs in (A) Acute glomerulonephritis (B) Acute pyelonephritis (C) Nephrosclerosis (D) Nephrotic syndrome

Last Answer : B

Specific gravity of urine is decreased in (A) Diabetes mellitus (B) Acute glomerulonephritis (C) Diarrhoea (D) Chronic glomerulonephritis

Description : Specific gravity of urine is decreased in (A) Diabetes mellitus (B) Acute glomerulonephritis (C) Diarrhoea (D) Chronic glomerulonephritis

Last Answer : B

Specific gravity of urine is raised in all of the following except (A) Diabetes mellitus (B) Diabetes insipidus (C) Dehydration (D) Acute glomerulonephritis

Description : Specific gravity of urine is raised in all of the following except (A) Diabetes mellitus (B) Diabetes insipidus (C) Dehydration (D) Acute glomerulonephritis

Last Answer : D

Polyuria can occur in (A) Diabetes mellitus (B) Diarrhoea (C) Acute glomerulonephritis (D) High fever

Description : Polyuria can occur in (A) Diabetes mellitus (B) Diarrhoea (C) Acute glomerulonephritis (D) High fever

Last Answer : B

The normal values for creatinine clearance varies from (A) 20–40 ml/min (B) 40–60 ml/min (C) 70–85 ml/min (D) 95–105 ml/min

Description : The normal values for creatinine clearance varies from (A) 20–40 ml/min (B) 40–60 ml/min (C) 70–85 ml/min (D) 95–105 ml/min

Last Answer : Answer : D

Glomerular filtration rate can be measured by (A) Endogenous creatinine clearance (B) Para-aminohippurate test (C) Addis test (D) Mosenthal test

Description : Glomerular filtration rate can be measured by (A) Endogenous creatinine clearance (B) Para-aminohippurate test (C) Addis test (D) Mosenthal test

Last Answer : Answer : A

Among the following, the most sensitive indicator of glomerular function is (A) Serum urea (B) Serum creatinine (C) Urea clearance (D) Creatinine clearance

Description : Among the following, the most sensitive indicator of glomerular function is (A) Serum urea (B) Serum creatinine (C) Urea clearance (D) Creatinine clearance

Last Answer : Answer : D

Average creatinine clearance in an adult man is about (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Description : Average creatinine clearance in an adult man is about (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Last Answer : Answer : C

Which of the following may be responsible for a hypokalaemic hypertension 1) Non-classical congenital adrenal hyperplasia 2) Barter's syndrome 3) Diabetic nephropathy 4) Liddle's syndrome 5) Type IV renal tubular acidosis

Description : Which of the following may be responsible for a hypokalaemic hypertension 1) Non-classical congenital adrenal hyperplasia 2) Barter's syndrome 3) Diabetic nephropathy 4) Liddle's syndrome 5) Type IV renal tubular acidosis

Last Answer : Answers-4 Liddle's syndrome is typically asscoiated with hypokalaemic hypertension and low renin and aldosterone concentrations - the so called pseudo-hyperaldosteronism. Barter's syndrome is associated ... , which may also be produced with diabetic nephropathy. Hence hyperkalaemia is more typical.

Which of the following condition is non-suppurativesequelae of Streptococcus pyogenA- Acute rheumatic fever B- Acute glomerulonephritis C- Erythema nodosum D- All of these

Description : Which of the following condition is non-suppurativesequelae of Streptococcus pyogen A- Acute rheumatic fever B- Acute glomerulonephritis C- Erythema nodosum D- All of these

Last Answer : All of these

A history of infection specifically caused by group A betahemolytic streptococci is associated with which of the following disorders? a) Acute glomerulonephritis Acute glomerulonephritis is also associated with varicella zoster virus, hepatitis B, and Epstein-Barr virus.

Description : A history of infection specifically caused by group A betahemolytic streptococci is associated with which of the following disorders? a) Acute glomerulonephritis Acute glomerulonephritis is ... chronic glomerulonephritis, systemic lupus erythematosus, multiple myeloma, and renal vein thrombosis.

Last Answer : a) Acute glomerulonephritis Acute glomerulonephritis is also associated with varicella zoster virus, hepatitis B, and Epstein-Barr virus.

Urine examination (Benedict’s test) of a 40 yr old obese male showed a brick red precipitate. This can result from all except Options: 1) Diabetes Mellitus 2) Drugs 3) Acute post-streptococcal glomerulonephritis 4) Cushing’s syndrome

Description : Urine examination (Benedict’s test) of a 40 yr old obese male showed a brick red precipitate. This can result from all except Options: 1) Diabetes Mellitus 2) Drugs 3) Acute post-streptococcal glomerulonephritis 4) Cushing’s syndrome

Last Answer : Correct Answer: 3) Acute post-streptococcal glomerulonephritis

Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow

Description : Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow

Last Answer : Answer : B

Measurement of insulin clearance test is a measure of (A) Glomerular filtration rate (B) Filtration factor (C) Renal plasma flow (D) Tubular secretory mass

Description : Measurement of insulin clearance test is a measure of (A) Glomerular filtration rate (B) Filtration factor (C) Renal plasma flow (D) Tubular secretory mass

Last Answer : Answer : A

Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass

Description : Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass

Last Answer : Answer : A

Creatinine clearance?

Description : Creatinine clearance?

Last Answer : DefinitionThe creatinine clearance test compares the level of creatinine in urine with the creatinine level in the blood. (Creatinine is a breakdown product of creatine, which is an important part of muscle. ... urine and blood samples, and looks at how much urine you collected in 24 hours.The clear

60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Description : 60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Last Answer : B. 50%

A 60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Description : A 60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Last Answer : B. 50%

In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Description : In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Last Answer : B. Digoxin

In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Description : In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Last Answer : B. Digoxin

Essential amino acids have been advocated as standard therapy for renal failure. Which of the following statements are true? A. Increased survival from acute renal failure has been reported with both essential and nonessential amino acid therapy of patients in renal failure. B. Essential amino acids retard the rise of blood urea nitrogen (BUN) secondary to decreased urea appearance. C. Essential amino acids and hypertonic dextrose are a convenient form of therapy for hyperkalemia. D. Essential amino acids decrease BUN and creatinine to the same degree as solutions containing excessive nonessential amino acids.

Description : Essential amino acids have been advocated as standard therapy for renal failure. Which of the following statements are true? A. Increased survival from acute renal failure has been reported ... BUN and creatinine to the same degree as solutions containing excessive nonessential amino acids.

Last Answer : Answer: BC DISCUSSION: Essential amino acids and hypertonic dextrose, as opposed to hypertonic dextrose alone, was reported by Abel and co-workers to be associated with a decreased mortality rate ... renal failure have not been carried out in sufficient numbers to yield answers to this question

Cytokines with clearly defined actions in acute inflammation and early tissue injury include which of the following? a. Cysteine-X-Cysteine (C-X-C) chemokines b. Tumor Necrosis Factor (TNFa) c. Transforming Growth Factor-b (TGF-b) d. Interleukin-6 (IL-6) e. Platelet Derived Growth Factor (PDGF)

Description : Cytokines with clearly defined actions in acute inflammation and early tissue injury include which of the following? a. Cysteine-X-Cysteine (C-X-C) chemokines b. Tumor Necrosis Factor (TNFa) c. Transforming Growth Factor-b (TGF-b) d. Interleukin-6 (IL-6) e. Platelet Derived Growth Factor (PDGF)

Last Answer : Answer: a, b, c, d, e Polypeptide mediators, such as TNFa and IL-1, are considered early response cytokines and are actively involved in the initiation of the ... of tissue repair. Thus, coagulation and platelet activation provide the initial foundation for subsequent cellular recruitment

Thrombolytic therapy instituted within 3-6 hours of onset of acute myocardial infarction affords the following benefit(s): A. Reduces mortality B. Reduces area of myocardial necrosis C. Preserves ventricular function D. All of the above

Description : Thrombolytic therapy instituted within 3-6 hours of onset of acute myocardial infarction affords the following benefit(s): A. Reduces mortality B. Reduces area of myocardial necrosis C. Preserves ventricular function D. All of the above

Last Answer : D. All of the above

Started within 4-6 hours of acute myocardial infarction, which of the following drug(s) can reduce the area of necrosis and the attendant mortality: A. Propranolol B. Glyceryl trinitrate C. Lignocaine D. Both ‘A’ and ‘B’ are correct

Description : Started within 4-6 hours of acute myocardial infarction, which of the following drug(s) can reduce the area of necrosis and the attendant mortality: A. Propranolol B. Glyceryl trinitrate C. Lignocaine D. Both ‘A’ and ‘B’ are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Description : If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Last Answer : A. More than the glomerular filtration rate

If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Description : If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Last Answer : A. More than the glomerular filtration rate

Neovascular glaucoma follows: a. Thrombosis of central retinal vein b. Acute congestive glaucoma c. Staphylococcal infection d. Hypertension

Description : Neovascular glaucoma follows: a. Thrombosis of central retinal vein b. Acute congestive glaucoma c. Staphylococcal infection d. Hypertension

Last Answer : ANSWER: A 

Urinary water loss is increased in (A) Diabetes mellitus (B) Diabetes insipidus (C) Chronic glomerulonephritis (D) All of these

Description : Urinary water loss is increased in (A) Diabetes mellitus (B) Diabetes insipidus (C) Chronic glomerulonephritis (D) All of these

Last Answer : Answer : D

Excretion of phenolsulphanpthalein (PSP) reflects (A) Glomerulonephritis (B) Maximaltabular excretory capacity (C) Filtration factor (D) Renal plasma flow

Description : Excretion of phenolsulphanpthalein (PSP) reflects (A) Glomerulonephritis (B) Maximaltabular excretory capacity (C) Filtration factor (D) Renal plasma flow

Last Answer : Answer : B

An increase in serum unconjugated bilirubin occurs in (A) Hemolytic jaundice (B) Obstructive jaundice (C) Nephritis (D) Glomerulonephritis

Description : An increase in serum unconjugated bilirubin occurs in (A) Hemolytic jaundice (B) Obstructive jaundice (C) Nephritis (D) Glomerulonephritis

Last Answer : Answer : A

Fixation of specific gravity of urine to 1.010 is found in (A) Diabetes insipidus (B) Compulsive polydypsia (C) Cystinosis (D) Chronic glomerulonephritis

Description : Fixation of specific gravity of urine to 1.010 is found in (A) Diabetes insipidus (B) Compulsive polydypsia (C) Cystinosis (D) Chronic glomerulonephritis

Last Answer : D

Specific gravity of urine increases in (A) Diabetes mellitus (B) Chronic glomerulonephritis (C) Compulsive polydypsia (D) Hypercalcemia

Description : Specific gravity of urine increases in (A) Diabetes mellitus (B) Chronic glomerulonephritis (C) Compulsive polydypsia (D) Hypercalcemia

Last Answer : A

Organic compound of small molecular size is (A) Urea (B) Uric acid (C) Creatinine (D) Phosphates

Description : Organic compound of small molecular size is (A) Urea (B) Uric acid (C) Creatinine (D) Phosphates

Last Answer : Answer : A

Progressive transmethylation of ethanolamine gives (A) Creatinine (B) Choline (C) Methionine (D) N-methyl nicotinamide

Description : Progressive transmethylation of ethanolamine gives (A) Creatinine (B) Choline (C) Methionine (D) N-methyl nicotinamide

Last Answer : Answer : C

When NH3 is perfused through a dog’s liver ______ is formed, while ______ is formed in the birds liver. (A) Urea, Uric acid (B) Urea, allantoin (C) Uric acid, creatinine (D) Uric acid, Urea

Description : When NH3 is perfused through a dog’s liver ______ is formed, while ______ is formed in the birds liver. (A) Urea, Uric acid (B) Urea, allantoin (C) Uric acid, creatinine (D) Uric acid, Urea

Last Answer : Answer : A