Description : Ceruloplasmin shows the activity (A) As ferroxidase (B) As reductase (C) As ligase (D) As transferase
Last Answer : Answer : A
Description : All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease
Last Answer : Answer : C
Description : Urease is a (A) Lyase (B) Ligase (C) Isomerase (D) Hydrolase
Last Answer : Answer : D
Description : The enzyme hexokinase is a (A) Hydrolase (B) Oxidoreductase (C) Transferase (D) Ligase
Description : Alkaptonuria occurs due to deficiency of the enzyme: (A) Maleylacetoacetate isomerase (B) Homogentisate oxidase (C) p-Hydroxyphenylpyruvate hydroxylase (D) Fumarylacetoacetate hydrolase
Last Answer : Answer : B
Description : Pyruvate dehydrogenase is a/an (A) Isomerase (B) Lyase (C) Ligase (D) Oxido reductase
Description : Retinal is converted into retinoic acid in the presence of (A) Retinal oxidase (B) Retinal carboxylase (C) Retinene reductase(D) Spontaneously
Description : Insulin degradation of disulfide bond formation is effected by (A) Pyruvate dehydrogenase (B) Xylitol reductase (C) Gutathione reductase (D) Xanthine oxidase
Description : Oxaloacetate is converted to aspartic acid by (A) Reductase (B) Oxidase (C) Transminase (D) Catalase
Description : In abetalipoproteinemia, the biochemical defect is in (A) Apo-B synthesis (B) Lipprotein lipase activity (C) Cholesterol ester hydrolase (D) LCAT activity
Description : Methotrexate blocks the synthesis of thymidine monophosphate by inhibiting the activity of the enzyme: (A) Dihydrofolate reductase (B) Orotate phosphoribosyl transferase (C) Ribonucleotide reductase (D) Dihydroorotase
Description : Which mineral element controls the activity of Nitrate reductase ? (A) Fe (B) Mo (C) Zn (D) Ca
Description : HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids
Description : In biosynthesis of cholesterol triparanol inhibits the activity of the enzyme: (A) ∆24 Reductase (B) Oxidosqualene-lanosterol cyclase (C) Isomerase (D) Squalene epoxidase ENZYMES 155
Description : The activity of HMG-CoA reductase is inhibited by (A) A fungal inhibitor mevastatin (B) Probucol (C) Nicotinic acid (D) Clofibrate
Description : Cholesterol by a feed back mechanism inhibits the activity of (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Thilase (D) Mevalonate kinase
Description : A deficiency of copper effects the formation of normal collagen by reducing the activity of which of the following enzyme? (A) Prolyl hydroxylase (B) Lysyl oxidase (C) Lysyl hydroxylase (D) Glucosyl transferase
Description : The deficiency of copper decreases the activity of the enzyme: (A) Lysine oxidase (B) Lysine hydroxylase (C) Tyrosine oxidase (D) Proline hydroxylase
Description : Activity of cytochrome oxidase is inhibited by (A) Sulphite (B) Sulphate (C) Arsenite (D) Cyanide
Description : The activity of mammalian L-amino acid oxidase, an FMN – flavo protein, is quite (A) Slow (B) Rapid (C) Both (A) and (B) (D) None of these
Description : What is ceruloplasmin? (A) Plasma protein (B) Stored form of copper (C) Both A and B (D) None of these
Description : Menke’s disease (Kinky or steel hair disease) is a X-linked disease characterized by (A) High levels of plasma copper (B) High levels of ceruloplasmin (C) Low levels of plasma copper and of ceuloplasmin (D) High level of hepatic copper
Description : In Wilson’s disease (A) Copper fails to be excreted in the bile (B) Copper level in plasma is decreased (C) Ceruloplasmin level is increased (D) Intestinal absorption of copper is decreased
Description : The normal serum concentration of ceruloplasmin in mg/100 ml varies between (A) 5–10 (B) 10–20 (C) 25–43 (D) 50–100
Description : Iron is a component of (A) Hemoglobin (B) Ceruloplasmin (C) Transferase (D) Transaminase
Description : Ceruloplasmin oxidizes (A) Copper (B) Iron (C) Both (A) and (B) (D) None of these
Description : Ceruloplasmin is absent in (A) Cirrhosis of liver (B) Wilson’s disease (C) Menke’s disease (D) Copper deficiency
Description : Proteins that carries Iron into different tissues is (A) Ceruloplasmin (B) Trans cortin (C) Mucoproteins (D) Glycoproteins
Description : A/G ratio is (A) Strength of proteins (B) ratio of serum proteins (C) ratio of ceruloplasmin (D) None of these
Description : Ceruloplasmin is (A) α1-globulin (B) α2-globulin (C) β-globulin (D) None of these
Description : An example of metalloprotein is (A) Casein (B) Ceruloplasmin (C) Gelatin (D) Salmine
Description : Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellular(MAI)? (a) Vancomycin (b) Clarithromycin (c) Erythromycin base (d) Troleandomycin (e) Erythromycin estolate
Last Answer : Ans: B
Description : Which enzyme is concerned with transfer of electrons? (A) Desmolase (B) Hydrolase (C) Dehydrogenase (D) Transaminase
Description : In which of the following types of enzymes, water may be added to a C—C double bond without breaking the bond? (A) Hydrolase (B) Hydratase (C) Hydroxylase (D) Oxygenase
Description : In which of the following types of enzyme water may be added to a C—C double bond without breaking the bond? (A) Hydrolase (B) Hydratase (C) Hydroxylase (D) Esterase
Description : The decarboxylation reaction in HMP shunt is catalysed by (A) Gluconolactone hydrolase (B) 6-Phosphogluconate dehydrogenase (C) 6-Phosphogluconate decarboxylase (D) Transaldolase
Description : Neonatal tyrosinemia is due to deficiency of the enzyme: (A) p-Hydroxyphenylpyruvate hydroxylase (B) Fumarylacetoacetate hydrolase (C) Phenylalanine hydroxylase (D) Tyrosine dehydrogenase
Description : Wolman’s disease is due to deficiency of (A) Cholesteryl ester hydrolase (B) Hexosaminidase A (C) α-Fucosidase (D) Arylsulphatase A
Description : The enzyme which can add water to a carbon-carbon double bond or remove water to create a double bond without breaking the bond is (A) Hydratase (B) Hydroxylase (C) Hydrolase (D) Esterase
Description : Pancreatic lipose is an enzyme which hydrolyzes facts. It acts as a/an (A) peptidase (B) hydrolase (C) carbohydrates (D) dehydrogenase
Description : Tyrosinosis is due to defect in the enzyme: (A) Fumarylacetoacetate hydrolase (B) p-Hydroxyphenylpyruvate hydroxylase (C) Tyrosine transaminase (D) Tyrosine hydroxylase
Description : Richner-Hanhart syndrome is due to defect in (A) Tyrosinase (B) Phenylalanine hydroxylase (C) Hepatic tyrosine transaminase (D) Fumarylacetoacetate hydrolase
Description : Transfer of the carbamoyl moiety of carbamoyl phosphate to ornithine is catalysed by a liver mitochondrial enzyme: (A) Carbamoyl phosphate synthetase (B) Ornithine transcarbamoylase (C) N-acetyl glutamate synthetase (D) N-acetyl glutamate hydrolase
Description : Give an example of a hydrolase.
Last Answer : Acetyl choline esterase.
Description : Molybdenum deficiency affects the activity of – (1) All of the given options (2) Chlorate reductase (3) Nitrogenase (4) Nitrate reductase
Last Answer : (4) Nitrate reductase Explanation: Numerous investigators have shown that nitrate nitrogen accumulates in higher plants and fungi which are deficient in molybdenum. In molybdenum-deficient plants grown in the ... in the decrease of free amino acids in the plants in comparison to normal plants.
Description : Molybdenum deficiency affects the activity of : (1) All of the given options (2) Chlorate reductase (3) Nitrogenase (4) Nitrate reductase
Last Answer : Nitrate reductase
Description : At the adrenergic synapse, the concentration of adrenaline in synaptic cleft: a. increased by cocaine which inhibit reuptake of adrenaline b. decreased by MAO (monoamine oxidase) - inhibitors c. controlled chiefly by the activity of the enzyme COMT d. increased by noradrenaline receptor blockers
Last Answer : increased by cocaine which inhibit reuptake of adrenaline
Description : Which of the following categories of medications may result in seizure activity if withdrawn suddenly? a) Tranquilizers Abrupt withdrawal of tranquilizers may result in anxiety, tension, ... may cause excessive respiratory depression during anesthesia due to an associated electrolyte imbalance.
Last Answer : a) Tranquilizers Abrupt withdrawal of tranquilizers may result in anxiety, tension, and even seizures if withdrawn suddenly.
Description : Choose the correct statement about allopurinol: A. It is a purine antimetabolite with antineoplastic activity B. It is a competitive inhibitor of xanthine oxidase C. It is inactive itself ... D. Both allopurinol as well as its metabolite alloxanthine are noncompetitive inhibitors of xanthine oxidase
Last Answer : B. It is a competitive inhibitor of xanthine oxidase
Description : In the biosynthesis of c-DNA, the joining enzyme ligase requires (A) GTP (B) ATP (C) CTP (D) UTP