Description : Which of the following statement(s) is/are true concerning metabolic derangements in sepsis and the systemic inflammatory response syndrome which may follow progressive shock? a. Alterations in glucose ... The serum aromatic amino acids fall rapidly as they are actively used in oxidative metabolism
Last Answer : Answer: b, c A broad spectrum of metabolic abnormalities become apparent in sepsis and the systemic inflammatory response syndrome following shock. Disruption of the normal cycles of carbohydrate, ... acetyl coenzyme A. This results in reduced serum level of leucine, isoleucine and valine
Description : In contrast to a patient undergoing an elective operation, which of the following statement(s) is/are true concerning a patient who has suffered a multiple trauma? a. Basal metabolic rates are ... is similar to their composition in skeletal muscle d. Fat and protein stores are rapidly depleted
Last Answer : Answer: b, d The degree of hypermetabolism is generally related to the severity of injury. Patients with long-bone fractures have a 15-25% increase in metabolic rate, whereas metabolic ... in injured subjects, if unfed, severely injured patients rapidly deplete their fat and protein stores
Description : Essential amino acids have been advocated as standard therapy for renal failure. Which of the following statements are true? A. Increased survival from acute renal failure has been reported ... BUN and creatinine to the same degree as solutions containing excessive nonessential amino acids.
Last Answer : Answer: BC DISCUSSION: Essential amino acids and hypertonic dextrose, as opposed to hypertonic dextrose alone, was reported by Abel and co-workers to be associated with a decreased mortality rate ... renal failure have not been carried out in sufficient numbers to yield answers to this question
Description : Skeletal muscle breakdown produces predominantly liberation of which two amino acids? A. Lysine. B. Tyrosine. C. Alanine. D. Glutamine. E. Arginine.
Last Answer : Answer: CD DISCUSSION: Alanine is released from skeletal muscle and extracted by the liver, where it is converted to new glucose. Glutamine is also released from muscle and participates in ... these two amino acids account for approximately two thirds of the nitrogen released from skeletal muscle
Description : Each of the following may contribute to formation of oedema EXCEPT C A. decreased plasma oncotic pressure increased intravascular hydrostatic pressure C. increased serum albumin D. decreased serum proteins
Last Answer : increased serum albumi
Description : Growth hormone causes hyperglycemia. It is a result of (A) Decreased peripheral utilization of glucose (B) Decreased hepatic production via gluconeogenesis (C) Increased glycolysis in muscle (D) Decrersed lipolysis
Last Answer : Answer : A
Description : The essential amino acids (A) must be supplied in the diet because the organism has lost the capacity to aminate the corresponding ketoacids (B) must be supplied in the diet because the ... amino acids which cannot be synthesized by the organism at a rate adequate to meet metabolic requirements
Last Answer : Answer : B
Description : The essential amino acids (A) Must be supplied in the diet because the organism has lost the capacity to aminate the corresponding ketoacids (B) Must be supplied in the diet because the ... amino acids which cannot be synthesized by the organism at a rate adequate to meet metabolic requirements
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Description : Which of the following is true of Gilbert's syndrome? 1) inheritance is autosomal recessive 2) serum conjugated bilirubin levels are elevated 3) serum bilirubin levels are decreased by fasting 4) serum bilirubin levels are decreased by liver enzyme inducers 5) there is bilirubinuria
Last Answer : Answers-4 Gilbert's syndrome is inherited in autosomal dominant fashion and affects 2-5% of the population. UDP glucuronyl transferase levels are reduced leading to an unconjugated hyperbilirubinaemia. ... the bilirubin is reabsorbed in the proximal tubule some bilirubin is detectable in the urine.
Description : Non essential amino acids (A) Are not components of tissue proteins (B) May be synthesized in the body from essential amino acids (C) Have no role in the metabolism (D) May be synthesized in the body in diseased states
Last Answer : (B) May be synthesized in the body from essential amino acids
Description : Optical isomers of all aminoacids exist except (A) Glycine (B) Arginine (C) Alanine (D) Hydroxy proline
Description : All followings are ketogenic aminoacids except (A) Leucine (B) Isoleucine (C) Phenyl alanine (D) Glycine
Last Answer : Answer : D
Description : Impaired galactose tolerance test suggests (A) Defect in glucose utilisation (B) Liver cell injury (C) Renal defect (D) Muscle injury
Description : Oedema can occur when (A) Plasma Na and Cl are decreased (B) Plasma Na and Cl are increased (C) Plasma proteins are decreased (D) Plasma proteins are increased
Last Answer : Answer : C
Description : Non-Protein amino acids are (A) Ornithine (B) β-alanine (C) γ-amino butyric acid (D) All of these
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) is decreased in (A) Rickets (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Renal failure
Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase
Description : Answer: a, b, c, d Free oxygen radicals are chemical species that are intermediates in the normal process of cellular respiration. Oxidants that are free radicals have been implicated as initiators of ... a. C-reactive protein b. Serum amyloid c. a -Proteinase inhibitor d. Fibrinogen e. Albumin
Last Answer : Answer: a, b, c, d The acute-phase response is a series of homeostatic responses of the organism to tissue injury in infection and inflammation. After an inflammatory stimulus occurs, a number ... 30% to 50% of the level before injury. The reason for the decrease in production is poorly understood
Description : Phrynoderma is a deficiency of (A) Essential fatty acids(B) Proteins (C) Amino acids (D) None of these
Description : Renal glycosuria occurs due to (A) Increased filtration of glucose in glomeruli (B) Increased secretion of glucose by renal tubular cells (C) Decreased reabsorption of glucose by renal tubular cells (D) Increased conversion of glycogen into glucose in tubular cells
Description : Which of the following statement(s) is/are true concerning protein/amino acid metabolism in man? a. The major source of amino acids is breakdown of circulating proteins b. The recommended daily ... balance refers to a decrease in nitrogen taken into the body versus the amount of nitrogen lost
Last Answer : Answer: b, d About 15% of the total body weight is made up of proteins, about half of which are intracellular and half extracellular. In man and other animals, dietary protein is the source of ... is exceeded by the amount of nitrogen lost in the urine, stool, skin, wounds, and fistula drainage
Description : Altering the amino acid profile in total parenteral nutrition solutions can be of benefit in certain conditions. Which of the following conditions are associated with a benefit by supplementation with the ... c. Short gut syndrome and glutamine d. Chronic renal failure and essential amino acids
Last Answer : Answer: a, c In a number of conditions, altering the amino acid profile of the total parenteral nutrition solution can be of benefit. TPN with amino acids of high biologic value ... Glutamine-enriched TPN partially attenuates villous atrophy and may be useful in treatment of short gut syndrome
Description : Which among the following is a nutritionally essential amino acid for man? (A) Alanine (B) Glycine (C) Tyrosine (D) Isoleucine
Description : Which among the following is an essential amino acid for man? (A) Alanine (B) Serine (C) Valine (D) Glutamic acid
Description : Which among the following is a nutritionally essential amino acid for man ? (A) Alanine (B) Glycine (C) Tyrosine (D) Tryptophan
Description : Is phenyl alanine an essential amino acid?
Last Answer : Yes.
Description : During compensation of respiratory alkalosis, all the following changes occur except (A) Decreased secretion of hydrogen ions by renal tubules (B) Increased excretion of sodium in urine (C) Increased excretion of bicarbonate in urine (D) Increased excretion of ammonia in urine
Description : What is impaired fasting glycemia (IFG).
Last Answer : In this condition, fasting plasma sugar is abnormal (between 110 and 126 mg/dl), but the 2-hour post-glucose value is within normal limits (less than 140 mg/dl).
Description : Impaired renal function is indicated when the amount of PSP excreted in the first 15 minutes is (A) 20% (B) 35% (C) 40% (D) 45%
Last Answer : A
Description : All the following statements about renal tubular acidosis are correct except (A) Renal tubules may be unable to reabsorb bicarbonate (B) Renal tubules may be unable to secrete hydrogen ions (C) Plasma chloride is elevated (D) Anion gap is decreased
Description : An amino acid not found in proteins is (A) β-Alanine (B) Proline (C) Lysine (D) Histidine
Description : A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the ... is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs
Last Answer : Answer: a, b, c, d, e Tumor cachexia appears to be mediated by TNFa. Lipopolysaccharide (LPS), as well as other cytokines, activate a variety of inflammatory cells, most ... chronic syndromes of anorexia, weight loss, and cachexia that are associated with both chronic infection and malignancy
Description : Introns in genes (A) Encode the amino acids which are removed during post-translational modification (B) Encode signal sequences which are removed before secretion of the proteins (C) Are the non-coding sequences which are not translated (D) Are the sequences that intervene between two genes
Description : Plasma becomes milky (A) Due to high level of HDL (B) Due to high level of LDL (C) During fasting (D) After a meal
Description : Sulphur is made available to the body by the amino acids: (A) Cystine and methionine (B) Taurine and alanine (C) Proline and hydroxyproline (D) Arginine and lysine MINERAL METABOLISM 191
Description : All the following amino acids are nonessential except (A) Alanine (B) Histidine (C) Cysteine (D) Proline
Description : Side chains of all following amino acids contain aromatic rings except (A) Phenyl alanine (B) Alanine (C) Tyrosine (D) Tryptophan
Description : Most amino acids are substrates for transamination except (A) Alanine (B) Threonine (C) Serine (D) Valine
Description : Side chains of all amino acids contain aromatic rings except (A) Pheynl alanine (B) Alanine (C) Tyrosine (D) Tryptophan
Description : All the standard amino acids except the following have one chiral ‘c’ atom: (A) Threonine, Isoleucine (B) Isoleucine, Alanine (C) Threonine, Alanine (D) Alanine, Glutamine
Description : All the following are branched chain amino acids except (A) Isoleucine (B) Alanine (C) Leucine (D) Valine
Description : The basic amino acids are (A) Lysine (B) Bile acids (C) Glycine (D) Alanine
Description : The amino acids involved in the synthesis of creatin are (A) Arginine, glycine, active methionine (B) Arginine, alanine, glycine (C) Glycine, lysine, methionine (D) Arginine, lysine, methionine
Description : The following occur in untreated insulin dependent diabetes mellitus: a. diuresis b. decreased plasma amino acid c. increased plasma fatty acid d. ketonuria
Last Answer : ketonuria
Description : An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine
Description : Hypolipidemic drugs reduce serum cholesterol and triacylglycerol. The effect of clofibrate is attributed to (A) Block in absorption from G.I.T. (B) Decrease in secretion of triacylglycerol and cholesterol ... by liver (C) Block in the reabsorption of bile acids (D) Decreased synthesis of cholesterol
Description : A modified amino acid solution with increased equimolar branched-chain amino acids and decreased aromatic amino acids has been proposed for patients with hepatic insufficiency. Which of the following ... D. In some studies of surgical patients, improvements in mortality have been reported.
Last Answer : Answer: D DISCUSSION: The use of modified amino acid solutions is based on the false neurotransmitter hypothesis of the cause of hepatic coma. According to this hypothesis, the imbalance ... in a group of patients with cirrhosis, decreasing morbidity and showing a trend toward decreased mortality
Description : ___ amino acids are commonly found in milk proteins, including the essential amino acids. a) 7 b) 12 c) 14 d) 19
Last Answer : d) 19