Deficiency of biotin results in decrease in (A) Amino acid synthesis (B) Lipid synthesis (C) Kidney (D) Fatty acid synthesis

Deficiency of biotin results in decrease in (A) Amino acid synthesis (B) Lipid synthesis (C) Kidney (D) Fatty acid synthesis
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A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP

Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP

Last Answer : Answer : A

Which of the following cofactors or their derivatives must be present for the conversion of acetyl CoA to malonyl CoA extramitochondrial fatty acid synthesis? (A) Biotin (B) FAD (C) FMN (D) ACP

Description : Which of the following cofactors or their derivatives must be present for the conversion of acetyl CoA to malonyl CoA extramitochondrial fatty acid synthesis? (A) Biotin (B) FAD (C) FMN (D) ACP

Last Answer : Answer : A

De novo synthesis of fatty acids requires all of the following except (A) Biotin (B) NADH (C) Panthothenic acid (D) ATP

Description : De novo synthesis of fatty acids requires all of the following except (A) Biotin (B) NADH (C) Panthothenic acid (D) ATP

Last Answer : Answer : D

Vitamin K is a cofactor for (A) Gamma carboxylation of glutamic acid residue (B) β-Oxidation of fatty acid (C) Formation of γ-amino butyrate (D) Synthesis of tryptophan

Description : Vitamin K is a cofactor for (A) Gamma carboxylation of glutamic acid residue (B) β-Oxidation of fatty acid (C) Formation of γ-amino butyrate (D) Synthesis of tryptophan

Last Answer : Answer : A

Deficiency of urea cycle enzymes results into accumulation of citrulline argininosuccinate arginine in the liver resulting in increasing concentration of …….. in the blood. (A) Calcium (B) Sodium (C) Ammonia (D) Lipid

Description : Deficiency of urea cycle enzymes results into accumulation of citrulline argininosuccinate arginine in the liver resulting in increasing concentration of …….. in the blood. (A) Calcium (B) Sodium (C) Ammonia (D) Lipid

Last Answer : Answer : C

The last step in synthesis of peptidoglycan is A- attachment of a peptide to muramic acid B- attaching two amino acids to form a cross-link C- attachment of a portion of peptidoglycan to a membrane lipid D- binding of penicillin to a membrane protein

Description : The last step in synthesis of peptidoglycan is A- attachment of a peptide to muramic acid B- attaching two amino acids to form a cross-link C- attachment of a portion of peptidoglycan to a membrane lipid D- binding of penicillin to a membrane protein

Last Answer : attaching two amino acids to form a cross-link

What is the mode of action of sulfonamide herbicide a). Amino acid synthesis inhibitor b). Photosynthesis inhibitor c). Lipid inhibitor d). Pigment inhibitor

Description : What is the mode of action of sulfonamide herbicide a). Amino acid synthesis inhibitor b). Photosynthesis inhibitor c). Lipid inhibitor d). Pigment inhibitor

Last Answer : a). Amino acid synthesis inhibitor

Maple syrup urine disease results from absence or serve deficiency of (A) Homogentisate oxidase (B) Phenylalanine hydroxylase (C) Branched chain amino acid transaminase (D) None of these

Description : Maple syrup urine disease results from absence or serve deficiency of (A) Homogentisate oxidase (B) Phenylalanine hydroxylase (C) Branched chain amino acid transaminase (D) None of these

Last Answer : Answer : D

Consumption of raw eggs can cause deficiency of (A) Biotin (B) Pantothenic acid (C) Riboflavin (D) Thiamin

Description : Consumption of raw eggs can cause deficiency of (A) Biotin (B) Pantothenic acid (C) Riboflavin (D) Thiamin

Last Answer : Answer : A

Consumption of raw eggs can cause deficiency of (A) Calcium (B) Lipoic acid (C) Biotin (D) Vitamin A

Description : Consumption of raw eggs can cause deficiency of (A) Calcium (B) Lipoic acid (C) Biotin (D) Vitamin A

Last Answer : Answer : C

Phrynoderma is a deficiency of (A) Essential fatty acids(B) Proteins (C) Amino acids (D) None of these

Description : Phrynoderma is a deficiency of (A) Essential fatty acids(B) Proteins (C) Amino acids (D) None of these

Last Answer : Answer : A

Essential fatty acid deficiency may complicate total parenteral nutrition (TPN). Which of the following statements are true? A. Essential fatty acid deficiency may be prevented by the administration of 1% to 2% of total calories as fat emulsion. B. Fat-free parenteral nutrition results in the appearance of plasma abnormalities, indicating essential fatty acid deficiency, within 7 to 10 days of initiation. C. An abnormal plasma eicosatrienoic-arachidonic acid ratio is always associated with essential fatty acid deficiency. D. Following initiation of fat-free parenteral nutrition, dry, scaly skin associated with a maculopapular rash indicates essential fatty acid deficiency.

Description : Essential fatty acid deficiency may complicate total parenteral nutrition (TPN). Which of the following statements are true? A. Essential fatty acid deficiency may be prevented by the ... , dry, scaly skin associated with a maculopapular rash indicates essential fatty acid deficiency.

Last Answer : Answer: BD DISCUSSION: Biochemical evidence of essential fatty acid deficiency may occur as early as 7 to 10 days following initiation of fat-free parenteral nutrition. The decrease in ... essential to the diagnosis of essential fatty acid deficiency, but this plasma abnormality is often present

The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD

Description : The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD

Last Answer : A

Biotin deficiency is characterized by the following except (A) Muscular pain (B) Anaemia (C) Nausea (D) Dermatitis

Description : Biotin deficiency is characterized by the following except (A) Muscular pain (B) Anaemia (C) Nausea (D) Dermatitis

Last Answer : Answer : B

Subacute combined degeneration of cord is caused due to deficiency of (A) Niacin (B) Cobalamin (C) Biotin (D) Thiamin VITAMINS 117

Description : Subacute combined degeneration of cord is caused due to deficiency of (A) Niacin (B) Cobalamin (C) Biotin (D) Thiamin VITAMINS 117

Last Answer : Answer : B

Transketolase activity is affected in (A) Biotin deficiency (B) Pyridoxine deficiency (C) PABA deficiency (D) Thiamine deficiency

Description : Transketolase activity is affected in (A) Biotin deficiency (B) Pyridoxine deficiency (C) PABA deficiency (D) Thiamine deficiency

Last Answer : B

A molecule of CO2 is captured by biotin when it acts as coenzyme for carboxylation reaction. The carboxyl group is covalently attached to (A) A nitrogen (N1) of the biotin molecule (B) Sulphur of thiophene ring (C) α-Amino group of lysine (D) α-Amino group of protein

Description : A molecule of CO2 is captured by biotin when it acts as coenzyme for carboxylation reaction. The carboxyl group is covalently attached to (A) A nitrogen (N1) of the biotin molecule (B) Sulphur of thiophene ring (C) α-Amino group of lysine (D) α-Amino group of protein

Last Answer : Answer : A

In biotin-containing enzymes, the biotin is bound to the enzyme by (A) An amide linkage to carboxyl group of glutamine (B) A covalent bond with CO2 (C) An amide linkage to an amino group of lysine (D) An amide linkage to α-carboxyl group of protein

Description : In biotin-containing enzymes, the biotin is bound to the enzyme by (A) An amide linkage to carboxyl group of glutamine (B) A covalent bond with CO2 (C) An amide linkage to an amino group of lysine (D) An amide linkage to α-carboxyl group of protein

Last Answer : Answer : C

Egg is poor in (A) Essential amino acids (B) Carbohydrates (C) Avidin (D) Biotin

Description : Egg is poor in (A) Essential amino acids (B) Carbohydrates (C) Avidin (D) Biotin

Last Answer : Answer : B

Deficiency of insulin results in (A) Rapid uptake of sugar (B) Low blood glucose level (C) Decrease urine output (D) Presence of glucose in urine

Description : Deficiency of insulin results in (A) Rapid uptake of sugar (B) Low blood glucose level (C) Decrease urine output (D) Presence of glucose in urine

Last Answer : Answer : D

The major lipid in chylomicrons is (A) Triglycerides (B) Phospholipids (C) Cholesterol (D) Free fatty acids

Description : The major lipid in chylomicrons is (A) Triglycerides (B) Phospholipids (C) Cholesterol (D) Free fatty acids

Last Answer : Answer : A

All the following processes occur rapidly in the membrane lipid bilayer except (A) Flexing of fatty acyl chains (B) Lateral diffusion of phospholipids (C) Transbilayer diffusion of phopholipids (D) Rotation of phospholipids around their long axes

Description : All the following processes occur rapidly in the membrane lipid bilayer except (A) Flexing of fatty acyl chains (B) Lateral diffusion of phospholipids (C) Transbilayer diffusion of phopholipids (D) Rotation of phospholipids around their long axes

Last Answer : C

Ketone bodies are synthesized from fatty acid oxidation products by which of the following organs? (A) Liver (B) Skeletal muscles (C) Kidney (D) Brain

Description : Ketone bodies are synthesized from fatty acid oxidation products by which of the following organs? (A) Liver (B) Skeletal muscles (C) Kidney (D) Brain

Last Answer : Answer : A

Action of insulin on lipid metabolism is (A) It increases lipolysis and increases triglyceride synthesis (B) It decreases lipolysis and increases triglyceride synthesis (C) It decreases lipolysis and decreases triglyceride synthesis (D) It increases synthesis of triglyceride and increased ketogenesis

Description : Action of insulin on lipid metabolism is (A) It increases lipolysis and increases triglyceride synthesis (B) It decreases lipolysis and increases triglyceride synthesis (C) It decreases ... and decreases triglyceride synthesis (D) It increases synthesis of triglyceride and increased ketogenesis

Last Answer : Answer : B

Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity

Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity

Last Answer : Answer : A

Epinephrine increases the concentration of free fatty acids in plasma by increasing (A) Extramitochondrial fatty acid synthesis (B) Mitochondrial fatty acid chain elongation (C) Microsomal fatty acid chain elongation (D) Lipolysis in adipose tissue

Description : Epinephrine increases the concentration of free fatty acids in plasma by increasing (A) Extramitochondrial fatty acid synthesis (B) Mitochondrial fatty acid chain elongation (C) Microsomal fatty acid chain elongation (D) Lipolysis in adipose tissue

Last Answer : Answer : D

Insulin increases (A) Protein synthesis (B) Fatty acid synthesis (C) Glycogen synthesis (D) All of these

Description : Insulin increases (A) Protein synthesis (B) Fatty acid synthesis (C) Glycogen synthesis (D) All of these

Last Answer : Answer : D

The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex

Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex

Last Answer : Answer : B

Intermediate in the denovo synthesis of triacyl glycerols include all the following except (A) Fatty acyl CoA (B) CDP diacyl glycerol (C) Glycerol-3-phosphate (D) Lysophosphatidic acid

Description : Intermediate in the denovo synthesis of triacyl glycerols include all the following except (A) Fatty acyl CoA (B) CDP diacyl glycerol (C) Glycerol-3-phosphate (D) Lysophosphatidic acid

Last Answer : Answer : B

Which of the following regulates lipolysis in adipocytes? (A) Activation of fatty acid synthesis mediated by CAMP (B) Glycerol phosphorylation to prevent futile esterification of fatty acids (C) Activation of triglyceride lipase as a result of hormone stimulated increases in CAMP levels (D) Activation of CAMP production by Insulin

Description : Which of the following regulates lipolysis in adipocytes? (A) Activation of fatty acid synthesis mediated by CAMP (B) Glycerol phosphorylation to prevent futile esterification of fatty acids (C) ... result of hormone stimulated increases in CAMP levels (D) Activation of CAMP production by Insulin

Last Answer : Answer : C

Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase

Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase

Last Answer : Answer : B

All statements regarding 3-OH-3 methyl glutaryl CoA are true except (A) It is formed in the cytoplasm (B) Required in ketogenesis (C) Involved in synthesis of Fatty acid (D) An intermediate in cholesterol biosynthesis

Description : All statements regarding 3-OH-3 methyl glutaryl CoA are true except (A) It is formed in the cytoplasm (B) Required in ketogenesis (C) Involved in synthesis of Fatty acid (D) An intermediate in cholesterol biosynthesis

Last Answer : Answer : B

A pathway that requires NADPH as a cofactor is (A) Fatty acid oxidation (B) Extra mitochondrial denovo fatty acid synthesis (C) Ketone bodies formation (D) Glycogenesis

Description : A pathway that requires NADPH as a cofactor is (A) Fatty acid oxidation (B) Extra mitochondrial denovo fatty acid synthesis (C) Ketone bodies formation (D) Glycogenesis

Last Answer : Answer : B

Acyl carrier protein is involved in the synthesis of (A) protein (B) glycogen (C) fatty acid outside the mitochondria (D) fatty acid in the mitochondria

Description : Acyl carrier protein is involved in the synthesis of (A) protein (B) glycogen (C) fatty acid outside the mitochondria (D) fatty acid in the mitochondria

Last Answer : Answer : C

Fatty acid synthesis takes place in the presence of the coenzyme: (A) NAD+ (B) Reduced NAD (C) NADP+ (D) Reduced NADP

Description : Fatty acid synthesis takes place in the presence of the coenzyme: (A) NAD+ (B) Reduced NAD (C) NADP+ (D) Reduced NADP

Last Answer : Answer : D

For extramitochondrial fatty acid synthesis, acetyl CoA may be obtained from (A) Citrate (B) Isocitrate (C) Oxaloacetate (D) Succinate

Description : For extramitochondrial fatty acid synthesis, acetyl CoA may be obtained from (A) Citrate (B) Isocitrate (C) Oxaloacetate (D) Succinate

Last Answer : Answer : A

NADPH required for fatty acid synthesis can come from (A) Hexose monophosphate shunt (B) Oxidative decarboxylation of malate (C) Extramitochondrial oxidation of isocitrate (D) All of these

Description : NADPH required for fatty acid synthesis can come from (A) Hexose monophosphate shunt (B) Oxidative decarboxylation of malate (C) Extramitochondrial oxidation of isocitrate (D) All of these

Last Answer : Answer : D

One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains (A) One —SH group (B) Two —SH groups (C) Three —SH groups (D) Four —SH groups FATS AND FATTY ACID METABOLISM 87

Description : One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains (A) One —SH group (B) Two —SH groups (C) Three —SH groups (D) Four —SH groups FATS AND FATTY ACID METABOLISM 87

Last Answer : Answer : B

Acetyl CoA carboxylase regulates fatty acid synthesis by which of the following mechanism? (A) Allosteric regulation (B) Covalent modification (C) Induction and repression (D) All of these

Description : Acetyl CoA carboxylase regulates fatty acid synthesis by which of the following mechanism? (A) Allosteric regulation (B) Covalent modification (C) Induction and repression (D) All of these

Last Answer : Answer : D

Which of the following is required as a reductant in fatty acid synthesis? (A) NADH (B) NADPH (C) FADH2 (D) FMNH2

Description : Which of the following is required as a reductant in fatty acid synthesis? (A) NADH (B) NADPH (C) FADH2 (D) FMNH2

Last Answer : Answer : B

For synthesis of prostaglandins, the essential fatty acids give rise to a fatty acid containing (A) 12 carbon atoms (B) 16 carbon atoms (C) 20 carbon atoms (D) 24 carbon atoms

Description : For synthesis of prostaglandins, the essential fatty acids give rise to a fatty acid containing (A) 12 carbon atoms (B) 16 carbon atoms (C) 20 carbon atoms (D) 24 carbon atoms

Last Answer : Answer : C

Acetyl CoA is not used for the synthesis of (A) Fatty acid (B) Cholesterol (C) Pyruvic acid (D) Citric acid

Description : Acetyl CoA is not used for the synthesis of (A) Fatty acid (B) Cholesterol (C) Pyruvic acid (D) Citric acid

Last Answer : C

What is the action of insulin on fatty acid synthesis?

Description : What is the action of insulin on fatty acid synthesis?

Last Answer : Insulin favours lipogenesis.

How is fatty acid synthesis regulated?

Description : How is fatty acid synthesis regulated? 

Last Answer : Key enzyme, acetyl CoA carboxylase, is stimulated by citrate and inhibited by palmitoyl CoA.

What are the sources of NADPH for fatty acid synthesis?

Description : What are the sources of NADPH for fatty acid synthesis?

Last Answer : Glucose-6-phosphate dehydrogenase, malic enzyme, cytoplasmic malate dehydrogenase.

What are the steps in which NADPH is used in fatty acid synthesis?

Description : What are the steps in which NADPH is used in fatty acid synthesis?

Last Answer : Step 4 (Keto acyl reductase) and Step 6 (Enoyl reductase).

Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?

Description : Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?

Last Answer : ATP citrate lyase.

What is the rate limiting enzyme of de novo synthesis of fatty acid?

Description : What is the rate limiting enzyme of de novo synthesis of fatty acid?

Last Answer : Acetyl CoA carboxylase.

What are the major differences between fatty acid synthesis and beta oxidation of fatty acid?

Description : What are the major differences between fatty acid synthesis and beta oxidation of fatty acid?

Last Answer : Beta oxidation is taking place in mitochondria, fatty acid synthesis is in cytoplasm. Oxidation enzymes are independent, synthetic enzymes are grouped as a multi-enzyme complex. During oxidation, 2 carbon units ... malonyl CoA. For oxidation, NAD and FAD are necessary, for synthesis, NADPH is used.

Vitamin deficiency that causes fatty liver includes all except (A) Vitamin E (B) Pyridoxine (C) Retionic acid (D) Pantothenic acid

Description : Vitamin deficiency that causes fatty liver includes all except (A) Vitamin E (B) Pyridoxine (C) Retionic acid (D) Pantothenic acid

Last Answer : Answer : C