Description : The main pathway for denovo synthesis of fatty acids occur in (A) Cytosol (B) Mitochondria (C) Microsomes (D) Nucleus
Last Answer : Answer : A
Description : The major site for elongation of medium chain fatty acids is (A) Mitochondria (B) Cytosol (C) Microsomes (D) All of these
Last Answer : Answer : C
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : Long chain fatty acids are first activated to acyl CoA in the (A) Cytosol (B) Mitochodria (C) Ribosomes (D) Microsome
Description : Oxidation of fatty acids occurs (A) In the cytosol (B) In the matrix of mitochondria (C) On inner mitochondrial membrane (D) On the microsomes
Last Answer : Answer : B
Description : De hovo synthesis of fatty acids occurs in (A) Cytosol (B) Mitochondria (C) Microsomes (D) All of these
Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis
Description : Glycolytic pathway is located in (A) Mitochondria (B) Cytosol (C) Microsomes (D) Nucleus
Description : The biosynthesis of Urea occurs mainly in the Liver: (A) Cytosol (B) Microsomes (C) Nucleus (D) Mitochondria
Last Answer : Answer : D
Description : Chain elongation of fatty acids in mammalian liver occurs in (A) Nucleus (B) Ribosomes (C) Lysosomes (D) Microsomes
Description : Chain elongation of fatty acids occurring in mammalian liver takes place in which of the following subcellular fractions of the cell? (A) Nucleus (B) Ribosomes (C) Lysosomes (D) Microsomes
Description : What is the sub cellular site for the βoxidation of fatty acids? (A) Nucleus (B) Mitochondria (C) Lysosome (D) Cytosol
Description : The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to (A) CO2 and water (B) Cholesterol (C) Fatty acids (D) Ketone bodies
Description : All long chain fatty acids with even number of carbon atoms are oxidized to a pool of _________ by β-oxidation. (A) CO2 (B) Propionic acid (C) Acetic acid (D) Acetyl CoA
Description : A soluble system for synthesis of fatty acids have been isolated from avian liver, required for the formation of long chain fatty acids by this system is (A) ATP (B) Acetyl CoA (C) NADPH (D) All of these
Description : While citrate is converted to isocitrate in the mitochondria, it is converted to _______ in the cytosol. (A) Acetyl CoA + oxaloacetate (B) Acetyl CoA + malonyl CoA (C) Acetyl CoA + Pyruvate (D) Acetyl CoA + acetoacetyl CoA
Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Description : De novo synthesis of pyrimidine nucleotides occurs in (A) Mitochondria (B) Cytosol (C) Microsomes (D) Ribosomes
Description : The biosynthesis of urea occurs mainly in the liver: (A) Cytosol (B) Mitochondria (C) Microsomes (D) Nuclei
Description : Lactate dehydrogenase is located in (A) Lysosomes (B) Mitochondria (C) Cytosol (D) Microsomes
Description : Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?
Last Answer : ATP citrate lyase.
Description : As a result of each oxidation a long chain fatty acid is cleaved to give (A) An acid with 3-carbon less and propionyl CoA (B) An acid with 2-carbon less and acetyl CoA (C) An acid with 2-carbon less and acetyl CoA (D) An acid with 4-carbon and butyryl CoA
Description : Monooxygenases are found in (A) Cytosol (B) Nucleus (C) Mitochondira (D) Microsomes
Description : β-Oxidation of odd-carbon fatty acid chain produces (A) Succinyl CoA (B) Propionyl CoA (C) Acetyl CoA (D) Malonyl CoA
Description : Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+
Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form
Description : β-oxidation of fatty acids is inhibited by (A) NADPH (B) Acetyl CoA (C) Malonyl CoA (D) None of these
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Description : Acetyl CoA required for de novo synthesis of fatty acids is obtained from (A) Breakdown of existing fatty acids (B) Ketone bodies (C) Acetate (D) Pyruvate
Description : Acetyl-CoA can be formed from (A) Pyruvate (B) Fatty acids (C) ketone bodies (D) All of these
Description : Fatty acids with odd number of carbon atoms yield acetyl-CoA and a molecule of (A) Succinyl-CoA (B) Propionyl-CoA (C) Malonyl-CoA (D) Acetoacetyl-CoA
Description : Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible: (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1, 6 diphosphate to ... phosphate (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : In the extra mitochondrial synthesis of fatty acids, CO2 is utilized (A) To keep the system anaerobic and prevent regeneration of acetyl CoA (B) In the conversion of malonyl to CoA hydroxybutyryl CoA (C ... of acetyl CoA to malonyl CoA (D) In the formation of acetyl CoA from 1 carbon intermediates
Description : Acetyl CoA formed from pyruvate can be used for the synthesis of all the following except (A) Glucose (B) Fatty acids (C) Cholesterol (D) Steroid hormones
Description : Propionyl CoA formed oxidation of fatty acids having an odd number of carbon atoms is converted into (A) Acetyl CoA (B) Acetoacetyl CoA (C) D-Methylmalonyl CoA (D) Butyryl CoA
Description : Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible. (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1,6-bisphosphate to fructose- ... (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Last Answer : C
Description : The conversion of pyruvate to acetyl CoA and CO2 (A) Is reversible (B) Involves the participation of lipoic acid (C) Depends on the coenzyme biotin (D) Occurs in the cytosol
Last Answer : B
Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier
Description : The synthesis of 3-hydroxy-3-methylglutaryl-CoA can occur (A) Only in mitochondria of all mammalian tissues (B) Only in the cytosol of all mammalian tissue (C) In both cytosol and mitochondria (D) In lysosomes
Description : Carnitine is required for the transport of (A) Triglycerides out of liver (B) Triglycerides into mitochondria (C) Short chain fatty acids into mitochondria (D) Long chain fatty acids into mitochondria
Description : All the following statements about acetyl CoA carboxylase are true except: (A) It is activated by citrate (B) It is inhibited by palmitoyl CoA (C) It can undergo covalent modification (D) Its dephosphorylated form is inactive
Description : Acetyl CoA carboxylase is activated by (A) Citrate (B) Insulin (C) Both (A) and (B) (D) None of these
Description : Fully activated pyruvate carboxylase depends upon the presence of (A) Malate and Niacin (B) Acetyl CoA and biotin (C) Acetyl CoA and thiamine pyrophosphate (D) Oxaloacetate and biotin
Description : All the following statements about carnitine are true except (A) It can be synthesised in the human body (B) It can be synthesized from methionine and lysine (C) It is required for transport of short chain fatty acids into mitochondria (D) Its deficiency can occur due to haemodialysis
Description : Mammalian DNA polymerase γ is located in (A) Nucleus (B) Nucleolus (C) Mitochondria (D) Cytosol
Description : All the enzymes involved in the synthesis of cholesterol are found in (A) Mitochondria (B) Golgi apparatus (C) Nucleus (D) Endoplasmic reticulum and cytosol
Description : The amino alcohol sphingosine is synthesized in (A) Mitochondria (B) Cytosol (C) Nucleus (D) Endoplasmic reticulum
Description : The enzyme pyruvate carboxylase is present in (A) Cytosol (B) Mitochondria (C) Nucleus (D) Golgi bodies
Description : The enzymes of the pentose phosphate pathway are found in the (A) Cytosol (B) Mitochondria (C) Nucleus (D) Endoplasmic reticulum
Description : The enzymes of β-oxidation are found in (A) Mitochondria (B) Cytosol (C) Golgi apparatus (D) Nucleus