Ochronosis is an important finding of (A) Tyrosinemia (B) Tyrosinosis (C) Alkaptonuria (D) Richner Hanhart syndrome FATS AND FATTY ACID METABOLISM 77

Ochronosis is an important finding of (A) Tyrosinemia (B) Tyrosinosis (C) Alkaptonuria (D) Richner Hanhart syndrome FATS AND FATTY ACID METABOLISM 77
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Plasma tyrosine level in Richner-Hanhart syndrome is (A) 1–2 mg/dL (B) 2–3 mg/dL (C) 4–5 mg/dL (D) 8–10 mg/dL

Description : Plasma tyrosine level in Richner-Hanhart syndrome is (A) 1–2 mg/dL (B) 2–3 mg/dL (C) 4–5 mg/dL (D) 8–10 mg/dL

Last Answer : Answer : C

Richner-Hanhart syndrome is due to defect in (A) Tyrosinase (B) Phenylalanine hydroxylase (C) Hepatic tyrosine transaminase (D) Fumarylacetoacetate hydrolase

Description : Richner-Hanhart syndrome is due to defect in (A) Tyrosinase (B) Phenylalanine hydroxylase (C) Hepatic tyrosine transaminase (D) Fumarylacetoacetate hydrolase

Last Answer : Answer : B

Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89

Description : Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89

Last Answer : Answer : A

All of the following substances have been used to estimate GFR except (A) Inulin (B) Creatinine (C) Phenol red (D) Mannitol FATS AND FATTY ACID METABOLISM 105

Description : All of the following substances have been used to estimate GFR except (A) Inulin (B) Creatinine (C) Phenol red (D) Mannitol FATS AND FATTY ACID METABOLISM 105

Last Answer : Answer : C

During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103

Description : During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103

Last Answer : Answer : A

The major source of cholesterol in arterial smooth muscle cells is from (A) IDL (B) LDL (C) HDL (D) Chylomicrons FATS AND FATTY ACID METABOLISM 101

Description : The major source of cholesterol in arterial smooth muscle cells is from (A) IDL (B) LDL (C) HDL (D) Chylomicrons FATS AND FATTY ACID METABOLISM 101

Last Answer : Answer : B

Cholesterol is excreted as such into ________. (A) Urine (B) Faeces (C) Bile (D) Tears FATS AND FATTY ACID METABOLISM 99

Description : Cholesterol is excreted as such into ________. (A) Urine (B) Faeces (C) Bile (D) Tears FATS AND FATTY ACID METABOLISM 99

Last Answer : Answer : C

Rancidity of butter is prevented by the addition of (A) Vitamin D (B) Tocopherols (C) Presence of priotin (D) Presence of ‘Cu’ FATS AND FATTY ACID METABOLISM 97

Description : Rancidity of butter is prevented by the addition of (A) Vitamin D (B) Tocopherols (C) Presence of priotin (D) Presence of ‘Cu’ FATS AND FATTY ACID METABOLISM 97

Last Answer : Answer : B

All active prostaglandins have atleast one double bond between positions: (A) 7 and 8 (B) 9 and 10 (C) 11 and 12 (D) 13 and 14 FATS AND FATTY ACID METABOLISM 95

Description : All active prostaglandins have atleast one double bond between positions: (A) 7 and 8 (B) 9 and 10 (C) 11 and 12 (D) 13 and 14 FATS AND FATTY ACID METABOLISM 95

Last Answer : Answer : A

Instead of ester link plasmalogens possess an other link in position: (A) α (B) β (C) γ (D) None of these FATS AND FATTY ACID METABOLISM 93

Description : Instead of ester link plasmalogens possess an other link in position: (A) α (B) β (C) γ (D) None of these FATS AND FATTY ACID METABOLISM 93

Last Answer : Answer : B

In haemolytic jaundice, urine shows (A) Absence of bile pigments and urobilinogen (B) Presence of bile pigments and urobilinogen (C) Absence of bile pigments and presence of urobilinogen (D) Presence of bile pigments and absence of urobilinogen FATS AND FATTY ACID METABOLISM 91

Description : In haemolytic jaundice, urine shows (A) Absence of bile pigments and urobilinogen (B) Presence of bile pigments and urobilinogen (C) Absence of bile pigments and presence of urobilinogen (D) Presence of bile pigments and absence of urobilinogen FATS AND FATTY ACID METABOLISM 91

Last Answer : Answer : C

One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains (A) One —SH group (B) Two —SH groups (C) Three —SH groups (D) Four —SH groups FATS AND FATTY ACID METABOLISM 87

Description : One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains (A) One —SH group (B) Two —SH groups (C) Three —SH groups (D) Four —SH groups FATS AND FATTY ACID METABOLISM 87

Last Answer : Answer : B

Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly (A) Taken up by liver (B) Taken up by extrahepatic tissues (C) Reutilised in adipose tissue (D) Excreted from the body FATS AND FATTY ACID METABOLISM 85

Description : Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly (A) Taken up by liver (B) Taken up by extrahepatic tissues (C) Reutilised in adipose tissue (D) Excreted from the body FATS AND FATTY ACID METABOLISM 85

Last Answer : Answer : A

Propionyl CoA is formed on oxidation of (A) Monounsaturated fatty acids (B) Polyunsaturated fatty acids (C) Fatty acids with odd number of carbon atoms (D) None of these FATS AND FATTY ACID METABOLISM 83

Description : Propionyl CoA is formed on oxidation of (A) Monounsaturated fatty acids (B) Polyunsaturated fatty acids (C) Fatty acids with odd number of carbon atoms (D) None of these FATS AND FATTY ACID METABOLISM 83

Last Answer : Answer : C

The Tm for PAH i.e the maximal secretory capacity of the tubule for PAH can be used to gavge the (A) Extent of tubular damage FATS AND FATTY ACID METABOLISM 81 (B) Impairment of the capacity of the tubule to perform osmotic work (C) Impairment of renal plasma flow (D) Glomerular filtration rate

Description : The Tm for PAH i.e the maximal secretory capacity of the tubule for PAH can be used to gavge the (A) Extent of tubular damage FATS AND FATTY ACID METABOLISM 81 (B) Impairment of the capacity of the tubule to perform osmotic work (C) Impairment of renal plasma flow (D) Glomerular filtration rate

Last Answer : Answer : A

Normal quantity of urobilinogen excreted in the feces per day is about (A) 10–25 mg (B) 50–250 mg (C) 300–500 mg (D) 700–800 mg FATS AND FATTY ACID METABOLISM 79

Description : Normal quantity of urobilinogen excreted in the feces per day is about (A) 10–25 mg (B) 50–250 mg (C) 300–500 mg (D) 700–800 mg FATS AND FATTY ACID METABOLISM 79

Last Answer : Answer : B

Palmitic, oleic or stearic acid ester of cholesterol used in manufacture of cosmetic creams is (A) Elaidic oil (B) Lanoline (C) Spermaceti (D) Chaulmoogric oil FATS AND FATTY ACID METABOLISM 75

Description : Palmitic, oleic or stearic acid ester of cholesterol used in manufacture of cosmetic creams is (A) Elaidic oil (B) Lanoline (C) Spermaceti (D) Chaulmoogric oil FATS AND FATTY ACID METABOLISM 75

Last Answer : Answer : B

In which of the following is mental retardation an expected finding? 1) Alkaptonuria 2) Cystinuria 3) Glycogen storage disease 4) Lactose intolerance 5) Maple syrup urine disease

Description : In which of the following is mental retardation an expected finding? 1) Alkaptonuria 2) Cystinuria 3) Glycogen storage disease 4) Lactose intolerance 5) Maple syrup urine disease

Last Answer : Answers-5 MENTAL RETARDATION. Fragile X syndrome-commonest male cause. Hypoxia at birth, intaventricular haemorrhage, rhesus disease, Congenital infections - toxoplasmosis, CMV, rubella ... with diet. -homocystinuria, phenylketonuria -maple syrup urine disease, tryptophanuria -galactosaemia

Neonatal tyrosinemia improves on administration of (A) Thiamin (B) Riboflavin (C) Pyridoxine (D) Ascorbic acid

Description : Neonatal tyrosinemia improves on administration of (A) Thiamin (B) Riboflavin (C) Pyridoxine (D) Ascorbic acid

Last Answer : Answer : A

Elevated blood argininosuccinate level is found in (A) Hyperargininemia (B) Argininosuccinic aciduria (C) Citrullinemia (D) Tyrosinosis

Description : Elevated blood argininosuccinate level is found in (A) Hyperargininemia (B) Argininosuccinic aciduria (C) Citrullinemia (D) Tyrosinosis

Last Answer : Answer : A

Tyrosinosis is due to defect in the enzyme: (A) Fumarylacetoacetate hydrolase (B) p-Hydroxyphenylpyruvate hydroxylase (C) Tyrosine transaminase (D) Tyrosine hydroxylase

Description : Tyrosinosis is due to defect in the enzyme: (A) Fumarylacetoacetate hydrolase (B) p-Hydroxyphenylpyruvate hydroxylase (C) Tyrosine transaminase (D) Tyrosine hydroxylase

Last Answer : Answer : A

Neonatal tyrosinemia is due to deficiency of the enzyme: (A) p-Hydroxyphenylpyruvate hydroxylase (B) Fumarylacetoacetate hydrolase (C) Phenylalanine hydroxylase (D) Tyrosine dehydrogenase

Description : Neonatal tyrosinemia is due to deficiency of the enzyme: (A) p-Hydroxyphenylpyruvate hydroxylase (B) Fumarylacetoacetate hydrolase (C) Phenylalanine hydroxylase (D) Tyrosine dehydrogenase

Last Answer : Answer : B

Absence of phenylalanine hydroxylase causes (A) Neonatal tyrosinemia (B) Phenylketonuria (C) Primary hyperoxaluria (D) Albinism

Description : Absence of phenylalanine hydroxylase causes (A) Neonatal tyrosinemia (B) Phenylketonuria (C) Primary hyperoxaluria (D) Albinism

Last Answer : Answer : D

HMG CoA is formed in the metabolism of (A) Cholesterol, ketones and leucine (B) Cholesterol, fatty acid and Leucine (C) Lysine, Lecuine and Isoleucine (D) Ketones, Leucine and Lysine

Description : HMG CoA is formed in the metabolism of (A) Cholesterol, ketones and leucine (B) Cholesterol, fatty acid and Leucine (C) Lysine, Lecuine and Isoleucine (D) Ketones, Leucine and Lysine

Last Answer : Answer : A

Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate

Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate

Last Answer : A

Niacin deficiency can occur in (A) Hartnup disease (B) Phenylketonuria (C) Alkaptonuria (D) None of these

Description : Niacin deficiency can occur in (A) Hartnup disease (B) Phenylketonuria (C) Alkaptonuria (D) None of these

Last Answer : Answer : A

Alkaptonuria occurs due to deficiency of the enzyme: (A) Maleylacetoacetate isomerase (B) Homogentisate oxidase (C) p-Hydroxyphenylpyruvate hydroxylase (D) Fumarylacetoacetate hydrolase

Description : Alkaptonuria occurs due to deficiency of the enzyme: (A) Maleylacetoacetate isomerase (B) Homogentisate oxidase (C) p-Hydroxyphenylpyruvate hydroxylase (D) Fumarylacetoacetate hydrolase

Last Answer : Answer : B

Esters of fatty acids with higher alcohols other than glycerol are said to be (A) Waxes (B) Fats (C) Both (A) and (B) (D) None of these

Description : Esters of fatty acids with higher alcohols other than glycerol are said to be (A) Waxes (B) Fats (C) Both (A) and (B) (D) None of these

Last Answer : Answer : A

Assertion :- Bile helps in emulsification of fats. Reason `:-` During emulsification fat is brokendown into fatty acid and glycerol.

Description : Assertion :- Bile helps in emulsification of fats. Reason `:-` During emulsification fat is brokendown into fatty acid and glycerol.

Last Answer : Assertion :- Bile helps in emulsification of fats. Reason `:-` During emulsification fat is brokendown ... D. If both Assertion & Reason are false.

What causes unsaturated fatty acid to have different shape than saturated fats?

Description : What causes unsaturated fatty acid to have different shape than saturated fats?

Last Answer : what are accurate comparisons of bases found in robins as opposed to bases found in sparrows

Adrneal cortical response is poor in (A) Kwashiorkor (B) Marasmus (C) Fatty liver (D) Atherosclerosis HORMONE METABOLISM 229

Description : Adrneal cortical response is poor in (A) Kwashiorkor (B) Marasmus (C) Fatty liver (D) Atherosclerosis HORMONE METABOLISM 229

Last Answer : Answer : A

Degradation of proteins to amino acids, glucose from carbohydrates and fatty acids from lipids is known as (A) Anabolism (B) Metabolism (C) Catabolism (D) Cretinism

Description : Degradation of proteins to amino acids, glucose from carbohydrates and fatty acids from lipids is known as (A) Anabolism (B) Metabolism (C) Catabolism (D) Cretinism

Last Answer : Answer : C

Link between glycolysis, Krebs’ cycle and β-oxidation of fatty acid or carbohydrate and fat metabolism is (a) oxaloacetic acid (b) succinic acid (c) citric acid (d) acetyl CoA.

Description : Link between glycolysis, Krebs’ cycle and β-oxidation of fatty acid or carbohydrate and fat metabolism is (a) oxaloacetic acid (b) succinic acid (c) citric acid (d) acetyl CoA.

Last Answer : (d) acetyl CoA.

Presence of RBC in urine is (a) alkaptonuria (b) urothiasis (c) hematuria (d) proteinuria.

Description : Presence of RBC in urine is (a) alkaptonuria (b) urothiasis (c) hematuria (d) proteinuria.

Last Answer : (c) hematuria

Which one of the following macromolecules would NOT normally be used for microbial energy metabolism. a. DNA b. Proteins c. Carbohydrates d. Fats

Description : Which one of the following macromolecules would NOT normally be used for microbial energy metabolism. a. DNA b. Proteins c. Carbohydrates d. Fats

Last Answer : b. Proteins

Assertion `:-` Fats are transported into the lacteals in the villi. Reason `:-` Fatty acids are insoluble in water.

Description : Assertion `:-` Fats are transported into the lacteals in the villi. Reason `:-` Fatty acids are insoluble in water.

Last Answer : Assertion `:-` Fats are transported into the lacteals in the villi. Reason `:-` Fatty acids are ... False. D. If both Assertion & Reason are false.

Cholesterol 1. Is a type of chlorophyll 2. Is a derivative of chloroform 3. Is a fatty alcohol found in animal fats 4. Causes hypertension The correct answers are: (a) 1 and 2 (b) 1, 3 and 4 (c) 3 and 4 (d) 1 and 4

Description : Cholesterol 1. Is a type of chlorophyll 2. Is a derivative of chloroform 3. Is a fatty alcohol found in animal fats 4. Causes hypertension The correct answers are: (a) 1 and 2 (b) 1, 3 and 4 (c) 3 and 4 (d) 1 and 4

Last Answer : Ans:(c)

Oils and fats are (a) Glyceryl esters of higher fatty acids (b) Acetyl esters of higher fatty acids (c) Ethyl esters of fatty acids (d) Methyl esters of fatty acids

Description : Oils and fats are (a) Glyceryl esters of higher fatty acids (b) Acetyl esters of higher fatty acids (c) Ethyl esters of fatty acids (d) Methyl esters of fatty acids

Last Answer : Ans:(a)

Bile, an emulsifier liquid, is made by the liver and later stored within the gallbladder and released in the duodenum. Bile is composed of bile salts, cholesterol and bile pigments. Bile salts are detergents, amphiphilic molecules, i.e., molecules with a polar water-soluble portion and a non-polar fat-soluble portion. This feature allows bile salts to enclose fats inside water-soluble micelles in a process called emulsification for them to be in contact with intestinal lipases, enzymes that break fats into simpler fatty acids and glycerol. Digestion System - Image Diversity: gallbladder

Description : Bile, an emulsifier liquid, is made by the liver and later stored within the gallbladder and released in the duodenum. Bile is composed of bile salts, cholesterol and bile pigments. ... enzymes that break fats into simpler fatty acids and glycerol. Digestion System - Image Diversity: gallbladder

Last Answer : What is the adnexal organ of the digestive system in which bile is stored?

Drying oils contain a fairly large proportion of – (1) fats (2) proteins (3) saturated fatty acids (4) unsaturated fatty acids

Description : Drying oils contain a fairly large proportion of – (1) fats (2) proteins (3) saturated fatty acids (4) unsaturated fatty acids

Last Answer : (4) unsaturated fatty acids Explanation: They contain a high percentage of "polyunsaturates" (polyunsaturated fatty acids). Most drying oils owe their drying properties to the presence of a large percentage of linolenic acid (which derives its name from "linseed"), which is highly unsaturated.

The process of neutralizing the fatty acids present in the oils or fats by adding sodium

Description : The process of neutralizing the fatty acids present in the oils or fats by adding sodium

Last Answer : hydroxide is called saponification.

Which of the following statements is not true about triacylglycerols? (a) When solids and semisolids at room temperature, they are called fats. (b) When liquids at room temperature, they are called oils. (c) When hydrolyzed, they produce glycerol and carboxylate salts. (d) Triacylglycerols with low melting points are composed of saturated fatty acids, causing them to be liquids at room temperature

Description : Which of the following statements is not true about triacylglycerols? (a) When solids and semisolids at room temperature, they are called fats. (b) When liquids at room temperature, they are ... low melting points are composed of saturated fatty acids, causing them to be liquids at room temperature

Last Answer : Triacylglycerols with low melting points are composed of saturated fatty acids, causing them to be liquids at room temperature

Fats differ from waxes in that fats have : (a) More unsaturation (b) Higher melting points (c) A glycerol backbone (d) Longer fatty acids

Description : Fats differ from waxes in that fats have : (a) More unsaturation (b) Higher melting points (c) A glycerol backbone (d) Longer fatty acids

Last Answer : A glycerol backbone

Fats as compared to oils have (A) More unsaturated glycerides of fatty acids (B) Less unsaturated glycerides of fatty acids (C) Much higher reactivity to oxygen (D) Lower melting point

Description : Fats as compared to oils have (A) More unsaturated glycerides of fatty acids (B) Less unsaturated glycerides of fatty acids (C) Much higher reactivity to oxygen (D) Lower melting point

Last Answer : (B) Less unsaturated glycerides of fatty acids

Drying oils contain a fairly large proportion of (1) fats (2) proteins (3) saturated fatty acids (4) unsaturated fatty acids

Description : Drying oils contain a fairly large proportion of (1) fats (2) proteins (3) saturated fatty acids (4) unsaturated fatty acids

Last Answer : unsaturated fatty acids

An important feature of Zellweger ’s syndrome is (A) Hypoglycemia (B) Accumulation of phytanic acid in tissues (C) Skin eruptions (D) Accumulation of C26-C38 polyenoic acid in brain tissues

Description : An important feature of Zellweger ’s syndrome is (A) Hypoglycemia (B) Accumulation of phytanic acid in tissues (C) Skin eruptions (D) Accumulation of C26-C38 polyenoic acid in brain tissues

Last Answer : Answer : D

Which of the following statement(s) is/are true concerning metabolic derangements in sepsis and the systemic inflammatory response syndrome which may follow progressive shock? a. Alterations in glucose metabolism lead to the development of efficient substrate utilization b. A progressive rise in serum triglyceride levels result from less efficient clearance and increased hepatic lipogenesis c. A net negative nitrogen balance occurs due to the oxidative metabolism of proteins to meet energy needs d. The serum aromatic amino acids fall rapidly as they are actively used in oxidative metabolism

Description : Which of the following statement(s) is/are true concerning metabolic derangements in sepsis and the systemic inflammatory response syndrome which may follow progressive shock? a. Alterations in glucose ... The serum aromatic amino acids fall rapidly as they are actively used in oxidative metabolism

Last Answer : Answer: b, c A broad spectrum of metabolic abnormalities become apparent in sepsis and the systemic inflammatory response syndrome following shock. Disruption of the normal cycles of carbohydrate, ... acetyl coenzyme A. This results in reduced serum level of leucine, isoleucine and valine

An important finding in Refsum’s disease is (A) Accumulation of ceramide trihexoside in the kidney (B) Accumulation of phytanic acid in the blood and tissues (C) Accumulation of gangliosides in brain and spleen (D) Skin eruptions

Description : An important finding in Refsum’s disease is (A) Accumulation of ceramide trihexoside in the kidney (B) Accumulation of phytanic acid in the blood and tissues (C) Accumulation of gangliosides in brain and spleen (D) Skin eruptions

Last Answer : Answer : B

Why is the Krebs cycle important in energy metabolism?

Description : Why is the Krebs cycle important in energy metabolism?

Last Answer : The Krebs cycle is essential for energy metabolism because electrons are given off at several places during the reactions of the cycle. At three different points of each cycle, pairs of electrons ... ATP molecules are in addition to the two ATP molecules resulting from the reactions of glycolysis.  

In thalassemia, an amino acid is substituted in (A) Alpha chain (B) Beta chain (C) Alpha and beta chains (D) Any chain MINERAL METABOLISM 195

Description : In thalassemia, an amino acid is substituted in (A) Alpha chain (B) Beta chain (C) Alpha and beta chains (D) Any chain MINERAL METABOLISM 195

Last Answer : Answer : D