Description : Intensive insulin therapy: A. Prevents the aggressive development of atherosclerosis in diabetic patients. B. Is not associated with unawareness of hypoglycemia. C. Improves peripheral neuropathy. D. ... . E. Is indicated in all patients with non-insulin-dependent diabetes mellitus (NIDDM).
Last Answer : Answer: C DISCUSSION: Intensive insulin therapy is indicated in patients with IDDM who can actively participate in their own management and the attainment of the goals set for ... or prevents progression of these complications; however, better glucose control may improve peripheral neuropathy
Description : Which of the following clinical characteristics is associated with Type 1 diabetes (previously referred to as insulin-dependent diabetes mellitus [IDDM])? a) Presence of islet cell antibodies ... Requirement for oral hypoglycemic agents Individuals with Type 1 diabetes need insulin to preserve life.
Last Answer : a) Presence of islet cell antibodies Individuals with Type 1 diabetes often have islet cell antibodies.
Description : The following feature disfavours use of oral hypoglycaemics in diabetes mellitus: A. Age at onset of disease over 40 years B. Insulin requirement more than 40 U/day C. Fasting blood sugar level between 100–200 mg/dl D. Associated obesity
Last Answer : B. Insulin requirement more than 40 U/day
Description : Which of the following clinical characteristics is associated with Type 2 diabetes (previously referred to as non-insulin-dependent diabetes mellitus [NIDDM])? a) Can control blood glucose ... islet cell antibodies Individuals with Type 2 diabetes do not demonstrate islet cell antibodies.
Last Answer : a) Can control blood glucose through diet and exercise Oral hypoglycemic agents may improve blood glucose levels if dietary modification and exercise are unsuccessful.
Description : Which of the following conditions may be detectable by growth monitoring? 1) Hyperthyroidism 2) Hypothyroidism 3) Pseudohypoparathyroidism 4) XYY Syndrome 5) Insulin dependent diabetes mellitus
Last Answer : Answers-2
Description : A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of ... serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations
Last Answer : Answers-2 a-An unusual but recognised feature particularly in children. However does not support a diagnosis of DKA. b-Suggests metabolic acidosis. c-'Normoglycaemic DKA' can occur and a glucose ... anorexia. e-Respiratory compensation leads to rapid deep (Kussmaul's) breathing. (Dr Mike Mulcahy)
Description : Restriction of salt intake is generally recommended in (A) Diabetes mellitus (B) Hypertension (C) Cirrhosis of liver (D) Peptic ulcer
Last Answer : B
Description : The following occur in untreated insulin dependent diabetes mellitus: a. diuresis b. decreased plasma amino acid c. increased plasma fatty acid d. ketonuria
Last Answer : ketonuria
Description : Obesity increases the risk of (A) Hypertension (B) Diabetes mellitus (C) Cardiovascular disease (D) All of these
Last Answer : D
Description : Two conditions in which gluconeogenesis is increased are (A) Diabetes mellitus and atherosclerosis (B) Fed condition and thyrotoxicosis (C) Diabetes mellitus and Starvation (D) Alcohol intake and cigarette smoking
Last Answer : C
Description : Hypoglycaemic coma can occur (A) In untreated diabetes mellitus (B) In starvation (C) After overdose of oral hypoglycaemic drugs (D) After overdose of insulin
Last Answer : Answer : D
Description : Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies
Last Answer : Answer : B
Description : The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation
Last Answer : Answer : A
Description : Higher rate of lipogenesis is associated with (A) High proportion of carbohydrate in diet (B) Restricted caloric intake (C) High fat diet (D) Deficiency of insulin
Description : Ketosis is associated with the disease: (A) Nephritis (B) Diabetes mellitus (C) Edema (D) Coronary artery diseases
Description : A man suffering from diabetes mellitus drinks water more frequently as he has to eliminate from the blood extra (1) glucose (2) insulin (4) glucagon (4) salt
Last Answer : (1) glucose Explanation: The diabetic person has higher sugar in blood. Glucose is a form of sugar.
Description : Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency? (a) Luteinising - Failure of ovulation hormone (b) Insulin - Diabetes insipidus (c) Thyroxine - Tetany (d) Parathyroid - Diabetes mellitus hormone
Last Answer : (a) Luteinising - Failure of ovulation hormone
Description : Which one of the following pairs is incorrectly matched? (a) Glucagon – Beta cells (source) (b) Somatostatin – Delta cells (source) (c) Corpus luteum – Relaxin (secretion) (d) Insulin – Diabetes mellitus (disease
Last Answer : (a) Glucagon – Beta cells (source)
Description : Match the following hormones with their respective disease. (A) Insulin (i) Addison's disease (B) Thyroxin (ii) Diabetes insipidus (C) Corticoids (iii)Acromegaly (D) Growth hormone (iv) Goitre (v) Diabetes mellitus Select the correct option ... (iii) (c) (ii) (iv) (iii) (i) (d) (v) (iv) (i) (iii)
Last Answer : (d) (v) (iv) (i) (iii
Description : Which of the following statements is NOT true about diabetes mellitus? A) Type II diabetes is much more common than type I. B) Insulin injections are required in both type I and type II ... -sugar diet. E) Symptoms of diabetes include excessive thirst, frequent urination, and glucose in the urine.
Last Answer : B) Insulin injections are required in both type I and type II diabetes.
Description : The present status of oral hypoglycaemics in diabetes mellitus is: A. They are the first choice drug in all cases B. They should be prescribed only if the patient refuses insulin injections C. ... I diabetes mellitus D. They are used first in most uncomplicated mild to moderate type 2 diabetics
Last Answer : D. They are used first in most uncomplicated mild to moderate type 2 diabetics
Description : The thiazolidinediones are mainly used as: A. Sole drug in type 1 diabetes mellitus B. Sole drug in type 2 diabetes mellitus C. Addon drug to a sulfonylurea and/or a biguanide in type 2 diabetes mellitus D. Addon drug to insulin in type 1 ... 18.34 1 8 . 3 4 B 18.35 1 8 . 3 5 D 18.36 1 8 . 3 6 C
Last Answer : C. Addon drug to a sulfonylurea and/or a biguanide in type 2 diabetes mellitus
Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above
Last Answer : D. All of the above
Description : Which of the following is not a sulfonylurea but acts by analogous mechanism to bring about quick and brief insulin release that is useful for normalizing meal time glycaemic excursions in type 2 diabetes mellitus: A. Glimepiride B. Miglitol C. Repaglinide D. Rosiglitazone
Last Answer : C. Repaglinide
Description : Insulin therapy is required for the following category/ categories of type 2 diabetes mellitus patients: A. Patients with ketoacidosis B. Patients undergoing surgery C. Pregnant diabetic D. All of the above
Description : Which of the following is not a specific indication for the more expensive monocomponent/human insulins: A. Insulin resistance B. Pregnant diabetic C. Sulfonylurea maintained diabetic posted for surgery D. Type 1 diabetes mellitus
Last Answer : D. Type 1 diabetes mellitus
Description : In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin
Last Answer : A. Prednisolone
Description : In diabetes mellitus, non-esterified fatty acid level in blood is increased, why?
Last Answer : Insulin inhibits hormone sensitive lipase, in diabetes, this inhibition is removed, so, more lipolysis is taking place.
Description : A young medical student has come to you with complaints of oligomenorrrhea, hirsuitism and weight gain, ultrasound reveals bulky ovaries with sub-capsular cysts. Most likely diagnosis is: a) Ovarian ... syndrome. c) Polycystic ovarian disease. d) Diabetes mellitus. e) Pelvic inflammatory disease
Last Answer : c) Polycystic ovarian disease.
Description : Which of the following factors can be associated with impaired wound healing? a. Chemotherapy b. Chronic steroid use c. Peripheral vascular disease d. Radiation therapy e. Diabetes mellitus
Last Answer : Answer: a, b, c, d, e Bone marrow suppression, a common consequence of chemotherapy, is detrimental to wound healing. Quantitative and qualitative lymphocyte and monocyte deficiency impairs cellular ... be a primary cause of impaired healing, and may be also a cofactor with other conditions
Description : Which of the following is/are not associated with increased likelihood of infection after major elective surgery? A. Age over 70 years. B. Chronic malnutrition. C. Controlled diabetes mellitus. D. Long-term steroid use. E. Infection at a remote body site.
Last Answer : Answer: C DISCUSSION: Controlled diabetes mellitus has been shown repeatedly not to be associated with increased likelihood of incisional infection provided one avoids operations on body parts ... site-are well-recognized adverse predictive factors and are identified in tables within the chapter
Description : Insulin receptors are decreased in number in (A) Obesity (B) Starvation (C) Hyperinsulinism (D) Kwashiorkor HORMONE METABOLISM 221
Description : Insulin Dependent Diabetes?
Last Answer : Type I Diabetes, also known as insulin dependent diabetes, is caused by the complete failure of the pancreas to produce insulin. While those with type II diabetes experience insulin ... be treated with pills or supplements, complete pancreatic failure must be treated using insulin therapy.
Description : The primary stimulus for insulin secretion is increased. (A) Blood level of epinephrine (B) Blood level of glucagon (C) Blood level of glucose (D) Water intake
Last Answer : Answer : C
Description : Excess intake of cobalt for longer periods leads to (A) Polycythemia (B) Megaloblastic anemia (C) Pernicious anemia (D) Microcytic anemia
Description : Fecal urobilinogen is decreased in (A) Obstruction of biliary duct (B) Hemolytic jaundice (C) Excess fat intake (D) Low fat intake
Description : Urinary water loss is increased in (A) Diabetes mellitus (B) Diabetes insipidus (C) Chronic glomerulonephritis (D) All of these
Description : Hypermagnesemia may be observed in (A) Hyperparathyroidism (B) Diabetes mellitus (C) Kwashiorkar (D) Primary aldosteronism
Description : Deficiency of magnesium may occur with (A) Alcoholism (B) Diabetes mellitus (C) Hypothyroidism (D) Advanced renal failure
Description : Alloxan can experimentally induce diabetes mellitus due to (A) Stimulation of α cells of the islets of langerhans (B) Necrosis of the β cells of the islets (C) Potentiation of insulinase activity (D) Epinephrine like action
Description : Hypocholesterolemia is found in (A) Thyrotoxicosis (B) Diabetes mellitus (C) Obstructive jaundice (D) Nephrotic syndrome
Description : Serum lipase level increases in (A) Paget’s disease (B) Gaucher’s disease (C) Acute pancreatitis (D) Diabetes mellitus
Description : Uremia occurs in (A) Cirrohsis of liver (B) Nephritis (C) Diabetes mellitus (D) Coronary thrombosis
Description : The essential fatty acids retard (A) Atherosclerosis (B) Diabetes mellitus (C) Nepritis (D) Oedema
Description : Which of the following condition is characterized by ketonuria but without glycosuria? (A) Diabetes mellitus (B) Diabetes insipidus (C) Prolonged starvation (D) Addison’s disease
Description : The β-lipoprotein fraction increases in severe (A) Diabetes Mellitus (B) Uremia (C) Nephritis (D) Muscular dystrophy
Description : Oliguria can occur in (A) Diabetes mellitus (B) Diabetes insipidus (C) Acute glomerulonephritis (D) Chronic glomerulonephritis
Description : Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89
Description : All the following statements about ketone bodies are true except (A) Their synthesis increases in diabetes mellitus (B) They are synthesized in mitchondria (C) They can deplete the alkali reserve (D) They can be oxidized in the liver