Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C) Increased serum alkaline phosphatase and decreased levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C) Increased serum alkaline phosphatase and decreased levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT
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Answer : D
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Patients with hepatocellular jaundice, as compared to those with purely obstructive jaundice tend to have (A) Lower serum ALP, LDH and AST activity (B) Lower serum ALP, Higher LDH and AST activity (C) Higher serum ALP, LDH and AST activity (D) Higher serum ALP, Lower LDH and AST activity

Description : Patients with hepatocellular jaundice, as compared to those with purely obstructive jaundice tend to have (A) Lower serum ALP, LDH and AST activity (B) Lower serum ALP, Higher LDH and AST activity (C) Higher serum ALP, LDH and AST activity (D) Higher serum ALP, Lower LDH and AST activity

Last Answer : Answer : B

Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Description : Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Last Answer : Answer : D

If results of the serum bilirubin, serum ALP, LDH and AST determinations suggest obstructive jaundice, the best confirmatory test would be the estimation of (A) Serum ALT (B) Serum 5’ nucleotidase (C) Serum Pseudo cholinesterase (D) None of these

Description : If results of the serum bilirubin, serum ALP, LDH and AST determinations suggest obstructive jaundice, the best confirmatory test would be the estimation of (A) Serum ALT (B) Serum 5’ nucleotidase (C) Serum Pseudo cholinesterase (D) None of these

Last Answer : Answer : B

Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Description : Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Last Answer : Answer : C

All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised due to increased release of the enzyme from liver cells (C) Bile salts may enter systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Last Answer : Answer : B

Serum albumin may be decreased in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) All of these

Description : Serum albumin may be decreased in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) All of these

Last Answer : Answer : B

An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C) A low blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Last Answer : Answer : C

All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Description : All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Last Answer : Answer : A

A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Description : A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Last Answer : Answer : B

Bile pigments are absent and urobilinogen increased in urine in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) Rotor’s syndrome

Description : Bile pigments are absent and urobilinogen increased in urine in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) Rotor’s syndrome

Last Answer : Answer : A

Galactose intolerance can occur in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) None of these

Description : Galactose intolerance can occur in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) None of these

Last Answer : Answer : B

Bile pigments are present and urobilinogen absent in urine in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) Crigler-Najjar syndrome

Description : Bile pigments are present and urobilinogen absent in urine in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) Crigler-Najjar syndrome

Last Answer : Answer : C

Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome

Description : Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome

Last Answer : Answer : A

Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits with the above serum biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Description : Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits ... biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Last Answer : Answers-2 Osteomalacia is associated with low calcium and phosphate with raised alkaline phosphatase. Serum biochemistry is normal in osteoporosis. Pagets disease is associated with normal ... renal failure when tertiary hyperparathyroidism sets in there is low calcium with raised phosphate.

In obstructive jaundice, faecal urobilinogen is (A) Absent (B) Decreased (C) Increased (D) Normal

Description : In obstructive jaundice, faecal urobilinogen is (A) Absent (B) Decreased (C) Increased (D) Normal

Last Answer : Answer : A

On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value? (A) Serum AST (B) Serum CK (C) Serum ALT (D) Serum LDH

Description : On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value? (A) Serum AST (B) Serum CK (C) Serum ALT (D) Serum LDH

Last Answer : Answer : D

On the third day of onset of acute myocardial infarction the enzyme elevated is (A) Serum AST (B) Serum CK (C) Serum LDH (D) Serum ALT

Description : On the third day of onset of acute myocardial infarction the enzyme elevated is (A) Serum AST (B) Serum CK (C) Serum LDH (D) Serum ALT

Last Answer : Answer : C

The liver enzyme which is sensitive indicator of liver cell injury and is most helpful in recognizing acute hepatocellular diseases is Options: 1) Alkaline Phosphatase 2) Aspartate aminotransferase 3) Gamma glutamyl Transpeptidase 4) Creatine Phosphokinase

Description : The liver enzyme which is sensitive indicator of liver cell injury and is most helpful in recognizing acute hepatocellular diseases is Options: 1) Alkaline Phosphatase 2) Aspartate aminotransferase 3) Gamma glutamyl Transpeptidase 4) Creatine Phosphokinase

Last Answer : Correct Answer: 2) Aspartate aminotransferase

Which one of the following tests would be most effective in ruling out the presence of active hepatocellular disease?A. Serum alanine aminotransferase (ALT) B. Serum total bilirubin C. cell surface markers D. None of these

Description : Which one of the following tests would be most effective in ruling out the presence of active hepatocellular disease? A. Serum alanine aminotransferase (ALT) B. Serum total bilirubin C. cell surface markers D. None of these

Last Answer : Serum alanine aminotransferase (ALT)

It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?

Description : It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?

Last Answer : ALP level is increased in both liver and bone diseases, but NTP is only in liver diseases. 

An increase in serum unconjugated bilirubin occurs in (A) Hemolytic jaundice (B) Obstructive jaundice (C) Nephritis (D) Glomerulonephritis

Description : An increase in serum unconjugated bilirubin occurs in (A) Hemolytic jaundice (B) Obstructive jaundice (C) Nephritis (D) Glomerulonephritis

Last Answer : Answer : A

The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Description : The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Last Answer : Answer : B

Alkaline phosphatase level in serum is elevated in which conditions?

Description : Alkaline phosphatase level in serum is elevated in which conditions?

Last Answer : Moderate increase is seen in hepatic diseases (infective hepatitis, alcoholic hepatitis). High levels may be noticed in obstructive jaundice or cholestasis. Very high levels are seen in bone diseases such as Pagetís disease, rickets, osteomalacia, osteoblastoma, metastatic carcinoma of bone.

In obstructive jaundice, urinary bilirubin is (A) Absent (B) Increased (C) Present (D) Present in small amount

Description : In obstructive jaundice, urinary bilirubin is (A) Absent (B) Increased (C) Present (D) Present in small amount

Last Answer : Answer : B

Fecal stercobilinogen is increased in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Viral hepatitis (D) Obstructive jaundice

Description : Fecal stercobilinogen is increased in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Viral hepatitis (D) Obstructive jaundice

Last Answer : Answer : B

Increased urobilinogen in urine and absence of bilirubin in the urine suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Viral hepatitis (D) Toxic jaundice

Description : Increased urobilinogen in urine and absence of bilirubin in the urine suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Viral hepatitis (D) Toxic jaundice

Last Answer : Answer : A

One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency

Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency

Last Answer : Answer : A

Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Last Answer : B

Serum acid phosphatase level is increased in which condition?

Description : Serum acid phosphatase level is increased in which condition?

Last Answer : Prostate carcinoma.

Answer: a, b, c, d Free oxygen radicals are chemical species that are intermediates in the normal process of cellular respiration. Oxidants that are free radicals have been implicated as initiators of reactions which lead to a variety of cellular injuries. Oxidants are derived from several sources, notably phagocytes. Among the effects of oxygen free radicals are membrane lipid peroxidation, DNA strand breaks, cytoskeletal disassembly and inhibition of glucose metabolism leading to decreased cellular ATP concentrations. (Figure 6-16) 187 Which of the following acute-phase protein levels are increased in human plasma following acute inflammation? a. C-reactive protein b. Serum amyloid c. a -Proteinase inhibitor d. Fibrinogen e. Albumin

Description : Answer: a, b, c, d Free oxygen radicals are chemical species that are intermediates in the normal process of cellular respiration. Oxidants that are free radicals have been implicated as initiators of ... a. C-reactive protein b. Serum amyloid c. a -Proteinase inhibitor d. Fibrinogen e. Albumin

Last Answer : Answer: a, b, c, d The acute-phase response is a series of homeostatic responses of the organism to tissue injury in infection and inflammation. After an inflammatory stimulus occurs, a number ... 30% to 50% of the level before injury. The reason for the decrease in production is poorly understood

Increased serum levels of which of the following may be associated with a decreased risk of atherosclerosis? (a) Very low-density lipoproteins (VLDL) (b) Low-density lipoproteins (LDL) (c) Intermediate – density lipoproteins (IDL) (d) High-density lipoproteins (HDL) (e) Cholesterol

Description : Increased serum levels of which of the following may be associated with a decreased risk of atherosclerosis? (a) Very low-density lipoproteins (VLDL) (b) Low-density lipoproteins (LDL) (c) Intermediate – density lipoproteins (IDL) (d) High-density lipoproteins (HDL) (e) Cholesterol

Last Answer : Ans: D

Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Description : Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Last Answer : Answer : D

Bile pigments are not present in urine in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Rotor’s syndrome

Description : Bile pigments are not present in urine in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Rotor’s syndrome

Last Answer : Answer : A

kernicterus can occur in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) All of these

Description : kernicterus can occur in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) All of these

Last Answer : Answer : A

Hypocholesterolemia is found in (A) Thyrotoxicosis (B) Diabetes mellitus (C) Obstructive jaundice (D) Nephrotic syndrome

Description : Hypocholesterolemia is found in (A) Thyrotoxicosis (B) Diabetes mellitus (C) Obstructive jaundice (D) Nephrotic syndrome

Last Answer : Answer : A

In obstructive jaundice, urine shows (A) Absence of bile pigments and urobilinogen (B) Presence of bile pigments and urobilinogen (C) Absence of bile pigments and presence of urobilinogen (D) Presence of bile pigments and absence of urobilinogen

Description : In obstructive jaundice, urine shows (A) Absence of bile pigments and urobilinogen (B) Presence of bile pigments and urobilinogen (C) Absence of bile pigments and presence of urobilinogen (D) Presence of bile pigments and absence of urobilinogen

Last Answer : Answer : D

Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89

Description : Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89

Last Answer : Answer : A

In obstructive jaundice prothrombin time (A) Remains normal (B) Decreases (C) Responds to vit K and becomes normal (D) Responds to vit K and increases

Description : In obstructive jaundice prothrombin time (A) Remains normal (B) Decreases (C) Responds to vit K and becomes normal (D) Responds to vit K and increases

Last Answer : Answer : C

The presence of bilirubin in the urine without urobilinogen suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Pernicious anemia (D) Damage to the hepatic parenchyma

Description : The presence of bilirubin in the urine without urobilinogen suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Pernicious anemia (D) Damage to the hepatic parenchyma

Last Answer : Answer : A

Immediate direct Vanden Bergh reaction indicates (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Megalobastic anemia

Description : Immediate direct Vanden Bergh reaction indicates (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Megalobastic anemia

Last Answer : Answer : B

A complete absence of fecal urobilinogen is strongly suggestive of (A) Obstruction of bile duct (B) Hemolytic jaundice (C) Intrahepatic cholestasis (D) Malignant obstructive disease

Description : A complete absence of fecal urobilinogen is strongly suggestive of (A) Obstruction of bile duct (B) Hemolytic jaundice (C) Intrahepatic cholestasis (D) Malignant obstructive disease

Last Answer : Answer : D

A mixture of conjugated and unconjugated bilirubin is found in the circulation in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Post hepatic jaundice

Description : A mixture of conjugated and unconjugated bilirubin is found in the circulation in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Post hepatic jaundice

Last Answer : Answer : B

Liver and skeletol measle disorders are characterized by on disk proportionate increase in which of the LDH isoenzyme fraction? (A) LDH-1 (B) LDH-1 and LDH-2 (C) LDH-3 and LDH-4 (D) LDH-2 and LDH-3 (E) LDH-5

Description : Liver and skeletol measle disorders are characterized by on disk proportionate increase in which of the LDH isoenzyme fraction? (A) LDH-1 (B) LDH-1 and LDH-2 (C) LDH-3 and LDH-4 (D) LDH-2 and LDH-3 (E) LDH-5

Last Answer : Answer : C

From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH

Description : From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH

Last Answer : Answer : A

Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these

Description : Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these

Last Answer : Answer : D

Which of the following is true of Gilbert's syndrome? 1) inheritance is autosomal recessive 2) serum conjugated bilirubin levels are elevated 3) serum bilirubin levels are decreased by fasting 4) serum bilirubin levels are decreased by liver enzyme inducers 5) there is bilirubinuria

Description : Which of the following is true of Gilbert's syndrome? 1) inheritance is autosomal recessive 2) serum conjugated bilirubin levels are elevated 3) serum bilirubin levels are decreased by fasting 4) serum bilirubin levels are decreased by liver enzyme inducers 5) there is bilirubinuria

Last Answer : Answers-4 Gilbert's syndrome is inherited in autosomal dominant fashion and affects 2-5% of the population. UDP glucuronyl transferase levels are reduced leading to an unconjugated hyperbilirubinaemia. ... the bilirubin is reabsorbed in the proximal tubule some bilirubin is detectable in the urine.

An important finding in Hyperammonemia type II is (A) Increased serum gluatmine level (B) Enlarged liver (C) Mental retardation (D) Increased carbamoyl phosphate synthetase level

Description : An important finding in Hyperammonemia type II is (A) Increased serum gluatmine level (B) Enlarged liver (C) Mental retardation (D) Increased carbamoyl phosphate synthetase level

Last Answer : Answer : C

Reviewing the laboratory findings of the client, the nurse would found which findings are elevated? 1. White blood cell count 2. Total serum bilirubin 3. Alkaline phosphate 4. Red blood cell count 5. Cholesterol 6. Serum amylase A. 1, 2, and 3 B. 2, 3, and 4 C. 3, 5, and 6 D. 1, 2, and 6

Description : Reviewing the laboratory findings of the client, the nurse would found which findings are elevated? 1. White blood cell count 2. Total serum bilirubin 3. Alkaline phosphate 4. Red blood cell count 5. Cholesterol 6. Serum amylase A. 1, 2, and 3 B. 2, 3, and 4 C. 3, 5, and 6 D. 1, 2, and 6

Last Answer : A. 1, 2, and 3

Pentosuria is a rare hereditary disease is characterized by increased urinary excretion of (A) L-xylulose (B) Xylitol (C) Xylulose 5-phosphate (D) Ribose 5-phosphate

Description : Pentosuria is a rare hereditary disease is characterized by increased urinary excretion of (A) L-xylulose (B) Xylitol (C) Xylulose 5-phosphate (D) Ribose 5-phosphate

Last Answer : Answer : A

An increased serum ‘Iron’ and decreased ‘Fe’ binding capacity are found in (A) Fe-deficiency anaemia (B) Sideroblastic anaemia (C) Thalassaemia (D) Anaemia of chromic disorders

Description : An increased serum ‘Iron’ and decreased ‘Fe’ binding capacity are found in (A) Fe-deficiency anaemia (B) Sideroblastic anaemia (C) Thalassaemia (D) Anaemia of chromic disorders

Last Answer : Answer : B