Description : A test to evaluate detoxifying function of liver is (A) Serum albumin: globulin ratio (B) Galactose tolerance test (C) Hippuric acid test (D) Prothrombin time
Last Answer : Answer : C
Description : Impaired galactose tolerance test suggests (A) Defect in glucose utilisation (B) Liver cell injury (C) Renal defect (D) Muscle injury
Last Answer : Answer : B
Description : Among the following, a test of Glomerular function is (A) Urea clearance (B) PSP excretion test (C) PAH clearance (D) Hippuric acid excretion test
Last Answer : Answer : D
Description : Hippuric acid is formed from (A) Benzoic acid and alanine (B) Benzoic acid glycine (C) Glucuronic acid and alanine (D) Glucuronic acid and glycine
Description : The amino acid which detoxicated benzoic acid to form hippuric acid is (A) Glycine (B) Alanine (C) Serine (D) Glutamic acid
Last Answer : Answer : A
Description : N-acetylneuraminic acid is an example of (A) Sialic acid (B) Mucic acid (C) Glucuronic acid (D) Hippuric acid
Last Answer : C
Description : Galactose is readily converted to glucose in (A) Liver (B) Intestine (C) Kidney (D) Adipose tissue
Description : Epinephrine stimulates glycogenolysis in (A) Liver (B) Muscle (C) Liver and muscle (D) Kidney
Description : Reactivation of inactive liver phosphorylase is normally favoured by (A) Insulin (B) Epinephrine (C) ACTH (D) Glucagon
Last Answer : D
Description : Removal of BSP dye by the liver involves conjugation with (A) Thiosulphate (B) Glutamine (C) Cystein component of glutathione (D) UDP glucuronate
Description : The ability of liver to remove a dye like BSP from the blood suggests a normal (A) Excretory function (B) Detoxification function (C) Metabolic function (D) Circulatory function
Description : Selwanof’s test is positive in (A) Glucose (B) Fructose (C) Galactose (D) Mannose
Description : A polysaccharide which is synthesized and stored in liver cells is (a) arabinose (b) glycogen (c) lactose (d) galactose.
Last Answer : (b) glycogen
Description : Which of the following is present as a marker in lysosomal enzymes to direct them to their destination? (A) Glucose-6-phosphate (B) Mannose-6-phosphate (C) Galactose-6-phosphate (D) N-Acetyl neuraminic acid
Description : A substrate for the enzyme aldolase is (A) galactose-6-phosphate (B) isocitric acid (C) Glucose-1-phosphate (D) Fructose 1, 6 diphosphate
Description : Cerebrosides are composed of (A) Sphingosine, fatty acids, glycerol and phosphoric acid (B) Sphingosine, fatty acids, galactose (C) Glycerol, fatty acids, galactose (D) Glycerol, fatty acids, galactose, sphingol
Description : Cerebrosides contain all the following except (A) Galactose (B) Sulphate (C) Sphingosine (D) Fatty acid
Description : Glycosphingolipids are a combination of (A) Ceramide with one or more sugar residues (B) Glycerol with galactose (C) Sphingosine with galactose (D) Sphingosine with phosphoric acid
Description : Galactose on oxidation with conc. HNO3 produces (A) Gluconic acid (B) Saccharic acid (C) Saccharo Lactone (D) Mucic acid
Description : Uridine diphosphate glucose (UDPG) is (A) Required for metabolism of galactose (B) Required for synthesis of glucuronic acid (C) A substrate for glycogen synthetase (D) All of the above
Description : Oxidation of galactose with conc HNO3 yields (A) Mucic acid (B) Glucuronic acid (C) Saccharic acid (D) Gluconic acid
Last Answer : A
Description : Repeating units of hyaluronic acid are (A) N-acetyl glucosamine and D-glucuronic acid (B) N-acetyl galactosamine and D-glucuronic acid (C) N-acetyl glucosamine and galactose (D) N-acetyl galactosamine and L- iduronic acid
Description : The best known cause of galactosemia is the deficiency of (A) Galactose 1-phosphate and uridyl transferase (B) Phosphoglucomutase (C) Galactokinase (D) Lactose synthase
Description : Cane sugar is known as (A) Galactose (B) Sucrose (C) Fructose (D) Maltose
Last Answer : B
Description : A cup of strong coffee would be expected to (A) Interfere with synthesis of prostaglandins (B) Decrease the effects of Glucagon (C) Enhance the effects of epinephrine (D) Provide the vitamin nicotinic acid
Description : Epinephrine increases the concentration of free fatty acids in plasma by increasing (A) Extramitochondrial fatty acid synthesis (B) Mitochondrial fatty acid chain elongation (C) Microsomal fatty acid chain elongation (D) Lipolysis in adipose tissue
Description : A cup of strong coffee would be expected to (A) Interfere with the synthesis of prostaglandins (B) Decrease the effect of glucagon (C) Enhance the effect of epinephrine (D) Provide the vitamin nicotinic acid
Description : The desaturation and chain elongation system of polyunsaturated fatty acid are enhanced by (A) Insulin (B) Glucagon (C) Epinephrine (D) Thyroxine
Description : Ascorbic acid is required to synthesise all of the following except (A) Collagen (B) Bile acids (C) Bile pigments (D) Epinephrine
Description : An 16-year-old man presents with polyuria and polydipsia. Which of the following may confirm the diagnosis of diabetes mellitus? 1) A random plasma glucose of >7.5 mmol/L 2) A finding of 3+ ketonuria 3) An HbA1c of 7.0% 4) A fasting plasma glucose of 7.5 mmol/L 5) An abnormal glucose tolerance test
Last Answer : Answers-4 The diagnosis is usually relatively easy to confirm in a symptomatic subject. A random glucose of >11.1 mmol/L or a fasting glucose of >7.0 mmol/L would be regarded as ... haemoglobin (HbA1c) is also highly suggestive but not diagnostic. A glucose tolerance test is rarely needed.
Description : A 35 year old male presents with weakness and tiredness. He is noted to be hyertensive. Electrolytes show a hypokalaemia and a hypomagnesaemia. What investigation would you select for this patient? ... Plasma renin toaldosterone ratio 3) Serum amylase 4) Serum calcium 5) Oral glucose tolerance test
Last Answer : Answers-2 The hypokalaemic hypertension with hypomagnesaemia suggests primary hyperaldosteronism. The most reliable assessment for this would be renin to aldosterone ratio.
Description : What is the major indication for doing an oral glucose tolerance test (OGTT)?
Last Answer : Patient has symptoms suggestive of diabetes mellitus, but fasting blood sugar value is inconclusive (between 100 and 126 mg/dl).
Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct
Last Answer : D. Both A and B are correct
Description : The antigenic antibody functions of proteins by denaturation are frequently (A) Not changed (B) Changed (C) Both (A) and (B) (D) None of these
Description : Sodium is involved in the active uptake of (A) D-Glucose (B) D-Galactose (C) L-Amino acids (D) All of these
Description : The pathogenesis of diabetic cataract involves accumulation of (A) Galactose (B) Mannitol (C) Sorbitol (D) Pyruvate
Description : Galactose 1-phosphate is converted to uridine diphosphate galactose, the reaction is catalysed by the enzyme: (A) Glactokinase (B) Galactose 1-phosphate uridyl transferase (C) Uridine diphospho galactose 4-epimerase (D) UDP glucose pyrophosphorylase
Description : Galactose is synthesized from glucose in (A) Mammary gland (B) Intestine (C) Kidney (D) Adipose tissue
Description : In the intestine the rate of absorption is highest for (A) Glucose and galactose (B) Fructose and mannose (C) Fructose and pentose (D) Mannose and pentose
Description : The sugar absorbed by fac i l itated diffusion and requiring Na independent transporter is (A) Glucose (B) Fructose (C) Galactose (D) Ribose
Description : Spermatozoa in seminal fluid utilises the following sugar for metabolism: (A) Galactose (B) Glucose (C) Sucrose (D) Fructose
Description : Carbohydrate moiety in cerebrosides is (A) Glucose (B) Sucrose (C) Galactose (D) Maltose
Description : Galactose intolerance can occur in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) None of these
Description : Milk is a good source of all of the following except (A) Essential amino acids (B) Vitamin C (C) Galactose (D) Calcium and phosphorous
Description : Starch and glycogen are polymers of (A) Fructose (B) Mannose (C) α−D-Glucose (D) Galactose
Description : Epimers of glucose is (A) Fructose (B) Galactose (C) Ribose (D) Deoxyribose
Description : Galactose is a main constituent of (A) Milk sugar (B) Honey (C) Cane sugar (D) Chitin
Description : Whcih of the following features are common to monosaccharides? (A) Contain asymmetric centres (B) Are of 2 types – aldoses and ketoses (C) Tend to exist as ring structures in solution (D) Include glucose, galactose and raffinose
Description : Which of the following reaction gives lactose? (A) UDP galactose and glucose (B) UDP glucose and galactose (C) Glucose and Galactose (D) Glucose, Galactose and UTP
Description : Cerebrosides consist of mostly of this sugar: (A) Glucose (B) Fructose (C) Galactose (D) Arabinose