Glomerular filtration rate can be measured by (A) Endogenous creatinine clearance (B) Para-aminohippurate test (C) Addis test (D) Mosenthal test

Glomerular filtration rate can be measured by (A) Endogenous creatinine clearance (B) Para-aminohippurate test (C) Addis test (D) Mosenthal test
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Creatinine EDTA clearance is a test to measure (A) Renal plasma flow (B) Filtration fraction (C) Glomerular filtration rate (D) Tubular function

Description : Creatinine EDTA clearance is a test to measure (A) Renal plasma flow (B) Filtration fraction (C) Glomerular filtration rate (D) Tubular function

Last Answer : Answer : C

Measurement of insulin clearance test is a measure of (A) Glomerular filtration rate (B) Filtration factor (C) Renal plasma flow (D) Tubular secretory mass

Description : Measurement of insulin clearance test is a measure of (A) Glomerular filtration rate (B) Filtration factor (C) Renal plasma flow (D) Tubular secretory mass

Last Answer : Answer : A

Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass

Description : Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass

Last Answer : Answer : A

Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow

Description : Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow

Last Answer : Answer : D

Among the following, the most sensitive indicator of glomerular function is (A) Serum urea (B) Serum creatinine (C) Urea clearance (D) Creatinine clearance

Description : Among the following, the most sensitive indicator of glomerular function is (A) Serum urea (B) Serum creatinine (C) Urea clearance (D) Creatinine clearance

Last Answer : Answer : D

Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow

Description : Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow

Last Answer : Answer : B

Measurement of inulin renal clearance is a measure for (A) Effective renal blood flow (B) Renal drug excretion rate (C) Active renal secretion (D) Glomerular filtration rate

Description : Measurement of inulin renal clearance is a measure for (A) Effective renal blood flow (B) Renal drug excretion rate (C) Active renal secretion (D) Glomerular filtration rate

Last Answer : (D) Glomerular filtration rate

If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Description : If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Last Answer : A. More than the glomerular filtration rate

If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Description : If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Last Answer : A. More than the glomerular filtration rate

Among the following, a test of tubular function is (A) Creatinine clearance (B) Inulin clearance (C) PAH clearance (D) PSP excretion test

Description : Among the following, a test of tubular function is (A) Creatinine clearance (B) Inulin clearance (C) PAH clearance (D) PSP excretion test

Last Answer : Answer : D

Phenolsulphonephthalein excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal blood low

Description : Phenolsulphonephthalein excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal blood low

Last Answer : Answer : D

The Tm for PAH i.e the maximal secretory capacity of the tubule for PAH can be used to gavge the (A) Extent of tubular damage FATS AND FATTY ACID METABOLISM 81 (B) Impairment of the capacity of the tubule to perform osmotic work (C) Impairment of renal plasma flow (D) Glomerular filtration rate

Description : The Tm for PAH i.e the maximal secretory capacity of the tubule for PAH can be used to gavge the (A) Extent of tubular damage FATS AND FATTY ACID METABOLISM 81 (B) Impairment of the capacity of the tubule to perform osmotic work (C) Impairment of renal plasma flow (D) Glomerular filtration rate

Last Answer : Answer : A

Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective 3) Increased Glomerular filtration rate is expected. 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+

Description : Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective ... 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+

Last Answer : Answers-2 H+ secretion, sodium reabsorption and ammonia production diminishes. RTA 4 is in effect hyporeninaemic hypoaldosteronism or failure of aldosterone action and thus helped treated with ... particularly. Aminoaciduria and increased urine bicarbonate are features of RTA types 1 and 2.

Among the following, a test of Glomerular function is (A) Urea clearance (B) PSP excretion test (C) PAH clearance (D) Hippuric acid excretion test

Description : Among the following, a test of Glomerular function is (A) Urea clearance (B) PSP excretion test (C) PAH clearance (D) Hippuric acid excretion test

Last Answer : Answer : D

The normal values for creatinine clearance varies from (A) 20–40 ml/min (B) 40–60 ml/min (C) 70–85 ml/min (D) 95–105 ml/min

Description : The normal values for creatinine clearance varies from (A) 20–40 ml/min (B) 40–60 ml/min (C) 70–85 ml/min (D) 95–105 ml/min

Last Answer : Answer : D

Creatinine clearance is deceased in (A) Acute tubular necrosis (B) Acute glomerulonephritis (C) Hypertension (D) Myopathies

Description : Creatinine clearance is deceased in (A) Acute tubular necrosis (B) Acute glomerulonephritis (C) Hypertension (D) Myopathies

Last Answer : Answer : D

Average creatinine clearance in an adult man is about (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Description : Average creatinine clearance in an adult man is about (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Last Answer : Answer : C

The blood sugar raising action of the hormone of suprarenal cortex is due to (A) Glyconeogenesis (B) Glycogenolysis (C) Glucagon like activity (D) due to inhibition of glomerular filtration of glucose

Description : The blood sugar raising action of the hormone of suprarenal cortex is due to (A) Glyconeogenesis (B) Glycogenolysis (C) Glucagon like activity (D) due to inhibition of glomerular filtration of glucose

Last Answer : Answer : A

The blood sugar raising action of the hormones of suprarenal cortex is due to (A) Gluconeogenesis (B) Glycogenolysis (C) Glucagon-like activity (D) Due to inhibition of glomerular filtration

Description : The blood sugar raising action of the hormones of suprarenal cortex is due to (A) Gluconeogenesis (B) Glycogenolysis (C) Glucagon-like activity (D) Due to inhibition of glomerular filtration

Last Answer : A

A fall in glomerular filtration rate (GFR) activates

Description : A fall in glomerular filtration rate (GFR) activates

Last Answer : A fall in glomerular filtration rate (GFR) activates A. adrenal medulla ot release adrenaline ... renin D. adrenal cortex to release aldosterone

A fall in glomerular filtration rate (GFR) activates

Description : A fall in glomerular filtration rate (GFR) activates

Last Answer : A fall in glomerular filtration rate (GFR) activates A. Juxtaglomerular cells to release ... adrenaline D. Posterior pituitary to release vasopressin

Glomerular filtration rate would be decreased by

Description : Glomerular filtration rate would be decreased by

Last Answer : Glomerular filtration rate would be decreased by A. An increase in the renal blood flow ... pressure D. Constriction of the efferent arteriole

The glomerular filtration rate is

Description : The glomerular filtration rate is

Last Answer : The glomerular filtration rate is A. 125 mL/min B. 180 L/day C. 1300 mL/min D. Both (1) and (2)

Glomerular filtration rate?

Description : Glomerular filtration rate?

Last Answer : DefinitionGlomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the tiny filters in the kidneys, called ... The blood collects into an airtight vial or tube attached to the needle. The elastic band is

The plasma half life of pencillin-G is longer in the new born because their (a) Plasma protein level is low (b) Drug metabolizing enzymes are immature (c) Glomerular filtration rate is low (d) Tubular transport mechanisms are not well developed

Description : The plasma half life of pencillin-G is longer in the new born because their (a) Plasma protein level is low (b) Drug metabolizing enzymes are immature (c) Glomerular filtration rate is low (d) Tubular transport mechanisms are not well developed

Last Answer : Ans: D

A fall in glomerular filtration rate (GFR) activates (a) juxtaglomerular cells to release renin (b) adrenal cortex to release aldosterone (c) adrenal medulla to release adrenaline (d) posterior pituitary to release vasopressin.

Description : A fall in glomerular filtration rate (GFR) activates (a) juxtaglomerular cells to release renin (b) adrenal cortex to release aldosterone (c) adrenal medulla to release adrenaline (d) posterior pituitary to release vasopressin.

Last Answer : (a) juxtaglomerular cells to release renin

The pharmacokinetics of drugs in the neonate differs from that in adults, because their: A. Intestinal transit is fast B. Drug metabolizing enzymes are overactive C. Tubular transport mechanisms are not well developed D. Glomerular filtration rate is high

Description : The pharmacokinetics of drugs in the neonate differs from that in adults, because their: A. Intestinal transit is fast B. Drug metabolizing enzymes are overactive C. Tubular transport mechanisms are not well developed D. Glomerular filtration rate is high

Last Answer : C. Tubular transport mechanisms are not well developed

The plasma half life of penicillin-G is longer in the new born because their: A. Plasma protein level is low B. Drug metabolizing enzymes are immature C. Glomerular filtration rate is low D. Tubular transport mechanisms are not well developed

Description : The plasma half life of penicillin-G is longer in the new born because their: A. Plasma protein level is low B. Drug metabolizing enzymes are immature C. Glomerular filtration rate is low D. Tubular transport mechanisms are not well developed

Last Answer : D. Tubular transport mechanisms are not well developed

Glomerular filtration of a drug is affected by its: A. Lipid solubility B. Plasma protein binding C. Degree of ionization D. Rate of tubular secretion

Description : Glomerular filtration of a drug is affected by its: A. Lipid solubility B. Plasma protein binding C. Degree of ionization D. Rate of tubular secretion

Last Answer : B. Plasma protein binding

09. The reasons determing bioavailability are: a) Rheological parameters of blood b) Amount of a substance obtained orally and quantity of intakes c) Extent of absorption and hepatic first-pass effect d) Glomerular filtration rate

Description : 09. The reasons determing bioavailability are: a) Rheological parameters of blood b) Amount of a substance obtained orally and quantity of intakes c) Extent of absorption and hepatic first-pass effect d) Glomerular filtration rate

Last Answer : C

The pharmacokinetics of drugs in the neonate differs from that in adults, because their: A. Intestinal transit is fast B. Drug metabolizing enzymes are overactive C. Tubular transport mechanisms are not well developed D. Glomerular filtration rate is high

Description : The pharmacokinetics of drugs in the neonate differs from that in adults, because their: A. Intestinal transit is fast B. Drug metabolizing enzymes are overactive C. Tubular transport mechanisms are not well developed D. Glomerular filtration rate is high

Last Answer : C. Tubular transport mechanisms are not well developed

The plasma half life of penicillin-G is longer in the new born because their: A. Plasma protein level is low B. Drug metabolizing enzymes are immature C. Glomerular filtration rate is low D. Tubular transport mechanisms are not well developed

Description : The plasma half life of penicillin-G is longer in the new born because their: A. Plasma protein level is low B. Drug metabolizing enzymes are immature C. Glomerular filtration rate is low D. Tubular transport mechanisms are not well developed

Last Answer : D. Tubular transport mechanisms are not well developed

Glomerular filtration of a drug is affected by its: A. Lipid solubility B. Plasma protein binding C. Degree of ionization D. Rate of tubular secretion

Description : Glomerular filtration of a drug is affected by its: A. Lipid solubility B. Plasma protein binding C. Degree of ionization D. Rate of tubular secretion

Last Answer : B. Plasma protein binding

Addis test is the measure of (A) Impairment of the capacity of the tubule to perform osmotic work (B) Secretory function of liver (C) Excretory function of liver (D) Activity of parenchymal cells of liver

Description : Addis test is the measure of (A) Impairment of the capacity of the tubule to perform osmotic work (B) Secretory function of liver (C) Excretory function of liver (D) Activity of parenchymal cells of liver

Last Answer : A

Filtration fraction can be calculated from (A) Standard urea clearance and PSP excretion (B) Maximum urea clearance and PSP excretion (C) Maximum urea clearance and PAH clearance (D) Inulin clearance and PAH clearance

Description : Filtration fraction can be calculated from (A) Standard urea clearance and PSP excretion (B) Maximum urea clearance and PSP excretion (C) Maximum urea clearance and PAH clearance (D) Inulin clearance and PAH clearance

Last Answer : Answer : A

Creatinine clearance?

Description : Creatinine clearance?

Last Answer : DefinitionThe creatinine clearance test compares the level of creatinine in urine with the creatinine level in the blood. (Creatinine is a breakdown product of creatine, which is an important part of muscle. ... urine and blood samples, and looks at how much urine you collected in 24 hours.The clear

60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Description : 60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Last Answer : B. 50%

A 60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Description : A 60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Last Answer : B. 50%

In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Description : In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Last Answer : B. Digoxin

In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Description : In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Last Answer : B. Digoxin

Which of the following factors is responsible for the formation of concentrated urine? (a) Hydrostatic pressure during glomerular filtration. (b) Low levels of antidiuretic hormone. (c) Maintaining hyperosmolarity towards the medullary interstitium in the kidneys. (d) Secretion of erythropoietin by Juxtaglomerular complex.

Description : Which of the following factors is responsible for the formation of concentrated urine? (a) Hydrostatic pressure during glomerular filtration. (b) Low levels of antidiuretic hormone. (c) ... the medullary interstitium in the kidneys. (d) Secretion of erythropoietin by Juxtaglomerular complex.

Last Answer : (c) Maintaining hyperosmolarity towards the medullary interstitium in the kidneys.

Which one of the following correctly explains the function of a specific part of the human nephron? (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the Bowman’s capsule (b) Henle’s loop : most reabsorption of the major substances from the glomerular filtrate (c) Distal convoluted tubule : reabsorption of K+ ions into the surrounding blood capillaries (d) Afferent arteriole : carries the blood away from the glomerulus towards renal vein.

Description : Which one of the following correctly explains the function of a specific part of the human nephron? (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the ... blood capillaries (d) Afferent arteriole : carries the blood away from the glomerulus towards renal vein.

Last Answer : (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the Bowman’s capsule

When the nurse notes that the post cardiac surgery patient demonstrates low urine output (< 25 ml/hr) with high specific gravity (> 1.025), the nurse suspects: a) Inadequate fluid volume Urine output of less than 25 ml/hr may indicate a decrease in cardiac output. A high specific gravity indicates increased concentration of solutes in the urine which occurs with inadequate fluid volume. b) Normal glomerular filtration Indices of normal glomerular filtration are output of 25 ml or greater per hour and specific gravity between 1.010 and 1.025. c) Overhydration Overhydration is manifested by high urine output with low specific gravity. d) Anuria The anuric patient does not produce urine.

Description : When the nurse notes that the post cardiac surgery patient demonstrates low urine output (< 25 ml/hr) with high specific gravity (> 1.025), the nurse suspects: a) Inadequate fluid volume Urine ... by high urine output with low specific gravity. d) Anuria The anuric patient does not produce urine.

Last Answer : a) Inadequate fluid volume Urine output of less than 25 ml/hr may indicate a decrease in cardiac output. A high specific gravity indicates increased concentration of solutes in the urine which occurs with inadequate fluid volume.

The following is true for gentamicin: A. It is more active in acidic medium B. It has a wide margin of safety C. It is excreted unchanged, mainly by glomerular filtration D. It primarily inhibits gram positive bacteria

Description : The following is true for gentamicin: A. It is more active in acidic medium B. It has a wide margin of safety C. It is excreted unchanged, mainly by glomerular filtration D. It primarily inhibits gram positive bacteria

Last Answer : C. It is excreted unchanged, mainly by glomerular filtration

The most important reason for the thiazides being only moderately efficacious diuretics is: A. About 9/10th of glomerular filtrate is reabsorbed proximal to their site of action B. Compensatory increase in reabsorption at sites not affected by these drugs C. They decrease glomerular filtration D. They have relatively flat dose response curve

Description : The most important reason for the thiazides being only moderately efficacious diuretics is: A. About 9/10th of glomerular filtrate is reabsorbed proximal to their site of action B. Compensatory ... these drugs C. They decrease glomerular filtration D. They have relatively flat dose response curve

Last Answer : A. About 9/10th of glomerular filtrate is reabsorbed proximal to their site of action

The most important channel of elimination of digoxin is: A. Glomerular filtration B. Tubular secretion C. Hepatic metabolism D. Excretion in bile

Description : The most important channel of elimination of digoxin is: A. Glomerular filtration B. Tubular secretion C. Hepatic metabolism D. Excretion in bile

Last Answer : A. Glomerular filtration

Interindividual variations in equieffective doses of a drug are most marked if it is disposed by: A. Glomerular filtration B. Tubular secretion C. Both glomerular filtration and tubular secretion D. Hepatic metabolism

Description : Interindividual variations in equieffective doses of a drug are most marked if it is disposed by: A. Glomerular filtration B. Tubular secretion C. Both glomerular filtration and tubular secretion D. Hepatic metabolism

Last Answer : D. Hepatic metabolism

High plasma protein binding: A. Increases volume of distribution of the drug B. Facilitates glomerular filtration of the drug C. Minimises drug interactions D. Generally makes the drug long acting

Description : High plasma protein binding: A. Increases volume of distribution of the drug B. Facilitates glomerular filtration of the drug C. Minimises drug interactions D. Generally makes the drug long acting

Last Answer : D. Generally makes the drug long acting

High plasma protein binding: A. Increases volume of distribution of the drug B. Facilitates glomerular filtration of the drug C. Minimises drug interactions D. Generally makes the drug long acting

Description : High plasma protein binding: A. Increases volume of distribution of the drug B. Facilitates glomerular filtration of the drug C. Minimises drug interactions D. Generally makes the drug long acting

Last Answer : D. Generally makes the drug long acting