Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase
Last Answer : Answer : A
Description : The adipose tissue lacks the enzyme _____________. a. Glycerol Kinase. b. Lipase. c. Glycerol Synthetase. d. Pyrophosphatase.
Last Answer : a. Glycerol Kinase.
Description : Fatty acids are a major energy source for the body. Which of the following statement(s) is/are true concerning the use of fatty acids as an energy source? a. Fatty acids are stored in ... 25% of total nonprotein caloric needs supplied via total parenteral nutrition should be in the form of fat
Last Answer : Answer: a, b, d In most tissues, fatty acids are readily oxidized for energy. They are especially important energy sources for the heart, liver and skeletal muscle. In ... administered to patients receiving total parenteral nutrition should comprise about 5-30% of total nonprotein caloric needs
Description : The enzyme glycerol kinase is low activity in (A) Liver (B) Kidney (C) Intestine (D) Adipose tissue
Last Answer : Answer : D
Description : Which of the following regulates lipolysis in adipocytes? (A) Activation of fatty acid synthesis mediated by CAMP (B) Glycerol phosphorylation to prevent futile esterification of fatty acids (C) ... result of hormone stimulated increases in CAMP levels (D) Activation of CAMP production by Insulin
Last Answer : Answer : C
Description : Glycerol-3-phosphate for the synthesis of triglycerides in adipose tissue is derived from (A) Phosphatidic acid (B) Diacylglycerol (C) Glycerol (D) Glucose
Description : Adipose tissue which is a store house for triacyl glycerol synthesis the same using (A) The glycerol released by hydrolysis of triacyl glycerol (B) The glycerol-3-phosphate obtained in the metabolism of glucose (C) 2-phosphoglycerate (D) 3-phosphoglycerate
Last Answer : Answer : B
Description : In adipose tissue, glycerol-3-phosphate required for the synthesis of triglycerides comes mainly from (A) Hydrolysis of pre-existing triglycerides (B) Hydrolysis of phospholipids (C) Dihydroxyacetone phosphate formed in glycolysis (D) Free glycerol
Description : In adipose tissue, what is the source of glycerol phosphate for triglyceride formation?
Last Answer : From dihydroxy acetone phosphate, derived from glucose.
Description : Insulin decreases the activity of (A) cAMP dependent protein kinase (B) HMG CoA-reductas (C) Phosphodiesterase (D) Acetyl CoA-carboxylase
Description : Covalent modification of an enzyme generally requires a (A) Hormone (B) cAMP (C) Protein kinase (D) All of these
Description : Glycerol is converted into glycerol-3- phosphate by (A) Thiokinase (B) Triokinase (C) Glycerol kinase (D) All of these
Description : An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase
Description : Which of the following enzymes incorporates inorganic phosphate into the substrate? (A) Phosphoglycerate kinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Enolase
Description : Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase
Description : In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase
Description : FAD is a coenzyme for (A) Succinate dehydrogenase (B) Glycerol-3-phosphate dehydrogenase (C) Sphingosine reductase (D) All of these
Description : When the stired triacylglycerol is lipolysed in the adipose tissue blood levels of _____ increased. (A) FFA only (B) Glycerol only (C) Free fatty acids (FFA) and Glycerol (D) Triacyl glycero
Description : Free glycerol cannot be used for triglyceride synthesis in (A) Liver (B) Kidney (C) Intestine (D) Adipose tissue
Description : Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly (A) Taken up by liver (B) Taken up by extrahepatic tissues (C) Reutilised in adipose tissue (D) Excreted from the body FATS AND FATTY ACID METABOLISM 85
Description : Protein kinase C is activated by (A) Cyclic AMP (B) Cyclic GMP (C) Diacyl glycerol (D) Inositol triphosphate
Description : Prostaglandins lower camp in (A) Adipose tissue (B) Lungs (C) Platelets (D) Adenohypophysis
Description : What is the mechanism of activation of hormone sensitive lipase?
Last Answer : A cascade through adenyl cyclase, cyclic AMP and kinase.
Description : Hormone sensitive lipase is activated by which hormones?
Last Answer : Growth hormone, corticosteroids, ACTH, adrenalin, and glucagon.
Description : Vasoconstrictor effect of ADH is mediated by (A) cAMP (B) cGMP (C) Protein kinase C (D) Angiotensin II
Description : Six months after beginning atorvastatin, the patient's total and LDL cholesterol concentrations remained above normal and he continued to have anginal attacks despite good adherence to his antianginal ... Increased endocytosis of HDL by the liver (e) Increased lipid hydrolysis by lipoprotein lipase
Last Answer : Ans: C
Description : One of the following enzymes does not change glycogen synthase a to b. (A) Glycogen synthase kinases 3, 4, 5 (B) Ca2+ calmodulin phosphorylase kinase (C) Ca2+ calmodulin dependent protein kinase (D) Glycogen phosphorylase a
Last Answer : D
Description : The output of free fatty acids from adipose tissue is reduced by (A) Insulin (B) Glucagon (C) Growth hormone (D) Epinephrine
Description : Release of free fatty acids from adipose tissue is increased by all of the following except (A) Glucagon (B) Epinephrine (C) Growth hormone (D) Insulin
Description : The best understood intracellular messenger is cyclic AMP (cAMP). Which of the following statement(s) concerning this intracellular messenger is/are correct? a. Intracellular cyclic AMP is constantly ... of adenylate cyclase d. cAMP is the only cyclic nucleotide active as an intracellular messenger
Last Answer : Answer: a, b The prototypic intracellular messenger is cAMP. To function as a mediator, the concentration of cAMP must change rapidly. In resting cells, cAMP is continuously being degraded by ... produce cGMP. Intracellular calcium ions also serve as second messengers in a large number of cells
Description : Glucose entry into the cells of the following organ/ tissue is highly dependent on the presence of insulin: A. Brain B. Liver C. Adipose tissue D. Kidney tubules
Last Answer : C. Adipose tissue
Description : The glycerol for fatty acid esterification in adipocytes is (A) For the most part, derived from glucose (B) Obtained primarily from phosphorylation of glycerol by glycerol kinase (C) Formed from gluconeogenesis (D) Formed from glycogenolysis ENZYMES 153
Description : The triacyl glycerol present in plasma lipoproteins are hydrolyzed by (A) Linqual lipase (B) Pancreatic lipase (C) Colipase (D) Lipoprotein lipase
Description : Salivary lipase converts dietary triglycerides into (A) Diglycerides and fatty acids (B) Monoglycerides and fatty acids (C) Glycerol and fatty acids (D) All of these
Description : This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP: (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thio kinase
Description : The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase
Description : Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase
Description : Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase
Description : In the glycolytic pathway, enolpyruvate is converted to ketopyruvate by (A) Pyruvate kinase (B) Phosphoenolpyruvate (C) Pyruvate dehydrogenase (D) Spontaneously
Description : Which of the following enzymes in Glycolytic pathway is inhibited by fluoride? (A) Glyceraldehyde-3-p dehydrogenase (B) Phosphoglycerate kinase (C) Pyruvate kinase (D) Enolase
Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency
Last Answer : C
Description : An important zinc containing enzyme is (A) Carboxypeptidase A (B) Isocitrate dehydrogenase (C) Cholinesterate (D) Lipoprotein lipase
Description : An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase
Description : In acute pancreatitis, the enzyme raised in first five days is (A) Serum amylase (B) Serum lactic dehydrogenase (C) Urinary lipase (D) Urinary amylase
Description : Example of an extracellular enzyme is (A) Lactate dehydrogenase (B) Cytochrome oxidase (C) Pancreatic lipase (D) Hexokinase
Description : In pKO1 plasmid, galactose kinase gene is a reporter gene which lacks ___________ gene. a. Initiation codon b. Promoter c. Activator d. Termination
Last Answer : b. Promoter
Description : The enzyme of the glycolic pathway, sensitive to inhibiton by fluoride ions is (A) Hexokinase (B) Aldolase (C) Enolase (D) Pyruvate kinase
Description : The effects of glucocorticoid hormones include: a. increase hepatic glycogen synthesis b. decrease glucose uptake by the adipose tissue c. decrease hepatic gluconeogesis d. increase protein synthesis in the skeletal muscles
Last Answer : . increase hepatic glycogen synthesis
Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate
Last Answer : B
Description : Glycerol can enter glycolytic pathway via (A) Dihydroxyacetone phosphate (B) 1, 3-Biphospoglycerate (C) 3-Phosphoglycerate (D) 2-Phosphoglycerate