Description : The enzyme deficient in Krabbe’s disease is (A) Hexosaminidase A(B) Arylsuphatase A (C) β-Galactosidase (D) α-Fucosidase
Last Answer : Answer : C
Description : Inherited deficiency of β−glucosidase causes (A) Tay-Sachs disease (B) Metachromatic leukodystrophy (C) Gaucher’s disease (D) Multiple sclerosis
Description : The enzyme deficient in Fabry’s disease is (A) α-Galactosidase (B) β-Galactosidase (C) α-Glucosidase (D) β-Glucosidase
Last Answer : Answer : A
Description : Ceramidase is deficient in (A) Fabry’s disease (B) Farber’s disease (C) Krabbe’s disease (D) Tay-Sachs disease
Last Answer : Answer : B
Description : The enzyme deficient in metachromatic leukodystrophy is (A) Arylsulphatase A (B) Hexosaminidase A (C) Ceramidase (D) Sphingomyelinase
Description : Hexosaminidase A is deficient in (A) Tay-Sachs disease (B) Gaucher’s disease (C) Niemann-Pick disease (D) Fabry’s disease
Description : Krabbe’s disease is due to the deficiency of the enzyme: (A) Ceramide lactosidase (B) Ceramidase (C) β-Galactosidase (D) GM1 β-Galactosidase
Description : Gaucher’s disease is due to the deficiency of the enzyme: (A) α-Fucosidase (B) β-Galactosidase (C) β-Glucosidase (D) Sphingomyelinase
Description : Gaucher’s disease is due to deficiency of the enzyme: (A) Sphingomyelinase (B) Glucocerebrosidase (C) Galactocerbrosidase (D) β-Galactosidase
Description : The enzyme deficient in Sandhoff’s disease is (A) α-Fucosidase (B) Hexosaminidase A and B (C) β-Galactosidase (D) β-Glucosidase
Description : Metachromatic leukodystrophy is due to deficiency of enzyme: (A) α-Fucosidase (B) Arylsulphatase A (C) Ceramidase (D) Hexosaminidase A
Description : Inherited deficiency of enzyme cerebrosidase produces (A) Fabry’s disease (B) Niemann pick disease (C) Gaucher’s disease (D) Tay-sach’s disease
Description : The concentration of sphingomyelins are increased in (A) Gaucher’s disease (B) Fabry’s disease (C) Fabrile disease (D) Niemann-Pick disease
Description : α-Galactosidase enzyme is defective in (A) Tay-sach’s disease (B) Refsum’s disease (C) Sandhoff’s disease (D) Fabry’s disease
Last Answer : Answer : D
Description : The enzyme ceramidase is deficient in (A) Farber’s disease (B) Fabry’s disease (C) Sandhoff’s disease(D) Refsum’s disease
Description : Farber’s disease is due to the deficiency of the enzyme: (A) α-Galactosidase (B) Ceramidase (C) β-Glucocerebrosidase (D) Arylsulphatase A.
Description : .Gene regulation governing lactose operon of E.coli that involves the lac I gene product is (a) negative and repressible because repressor protein prevents transcription (b) feedback inhibition ... be induced by lactose (d) negative and inducible because repressor protein prevents transcription.
Last Answer : (d) negative and inducible because repressor protein prevents transcription.
Description : Lac operon’ in E. coli, is induced by (a) ‘I’ gene (b) promoter gene (c) β-galactosidase (d) lactose.
Last Answer : (c) β-galactosidase
Description : Which enzyme will be produced in a cell if there is a nonsense mutation in the lac Y gene? (a) Transacetylase (b) Lactose permease and transacetylase (c) β-galactosidase (d) Lactose permease
Last Answer : β-galactosidase
Description : Gene regulation governing lactose operon of E.coli that involves the lac I gene product is (a) negative and repressible because repressor protein prevents transcription (b) feedback inhibition ... be induced by lactose (d) negative and inducible because repressor protein prevents transcription.
Description : Isoxsuprine increases limb blood flow in normal individuals, but is of limited efficacy in Buerger's disease, because in this disease: A. Vasodilator β adrenoceptors are deficient B. There is loss ... affected limb is reduced by organic obstruction D. The drug is not delivered to the affected site
Last Answer : C. Blood flow to the affected limb is reduced by organic obstruction
Description : Serum ferroxidase level decreases in (A) Gaucher’s disease (B) Cirrhosis of liver (C) Acute pancreatitis (D) Wilson’s disease ENZYMES 143
Description : Serum lipase level increases in (A) Paget’s disease (B) Gaucher’s disease (C) Acute pancreatitis (D) Diabetes mellitus
Description : Fabry’s disease is due to the deficiency of the enzyme: (A) Ceramide trihexosidase (B) Galactocerebrosidase (C) Phytanic acid oxidase (D) Sphingomyelinase
Description : Mental retardation occurs in (A) Tay-Sachs disease (B) Gaucher’s disease (C) Niemann-Pick disease (D) All of these
Description : An important finding of Fabry’s disease is (A) Skin rash (B) Exophthalmos (C) Hemolytic anemia (D) Mental retardation
Description : Protein deficiency disease is known as (A) Cushing’s disease (B) Fabry’s disease (C) Parkinson’s disease (D) Kwashiorkor and marasmus
Description : Gaucher's Disease is associated with the deficiency of : 1) Hexosaminidase A 2) Sphingomyelinase 3) Arylsulphatase-A 4) B- Glucosidase 5) Iduronidase
Last Answer : Answers-4 Hexosaminidase A deficiency is associated Tay-Sachs disease. Sphingomyelinase deficiency is associated with Niemann-Pick disease. Arylsulphatase-A deficiency is associated with metachromic leucodystrophy.Iduronidase deficiency is associated with Hurlers syndrome.
Description : Methylene blue staining of metachromatic granules is diagnostic for which of the following bacteria? a. Mycobacterium Tuberculosis b. Coiynebacterium Diphtheriae c. Chlamydia Pneumoniae d. Bordetella Pertussis
Last Answer : b. Coiynebacterium Diphtheriae
Description : Glucose-6-phosphatase is absent or deficient in (A) Von Gierke’s disease (B) Pompe’s disease (C) Cori’s disease (D) McArdle’s disease
Last Answer : A
Description : Assetion: Insertion of recombinant DNA within the coding sequence of `beta-`galactosidase result n colourless colonies. Reason : Presence of insert re
Last Answer : Assetion: Insertion of recombinant DNA within the coding sequence of `beta-`galactosidase result n ... D. If both assertion and reason are false
Description : The colonies of recombinant bacteria appear white in contrast to blue colonies of non-recombinant bacteria because of (a) insertional inactivation of alpha galactosidase in recombinant ... beta galactosidase (d) insertional inactivation of alpha galactosidase in non-recombinant bacteria.
Last Answer : (c) non-recombinant bacteria containing beta galactosidase
Description : Match the following genes of the Lac operon with their respective products. (A) i gene (i) b-galactosidase (B) z gene (ii) Permease (C) a gene (iii)Repressor (D) y gene (iv) Transacetylase Select the correct option. (A) (B) (C) ( ... ) (iii) (ii) (iv) (c) (iii) (i) (ii) (iv) (d) (iii) (i) (iv) (ii)
Last Answer : (a) (iii) (iv) (i) (ii)
Description : .E.coli cells with a mutated z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because (a) the lac operon is constitutively active in these cells ( ... coli cells do not utilise lactose (d) they cannot transport lactose from the medium into the cell.
Last Answer : (b) they cannot synthesise functional beta galactosidase
Last Answer : d) (iii) (i) (iv) (ii)
Description : Which group of three of the following five statements (1-5) contain all three correct statements regarding beri-beri? 1. A crippling disease prevalent among the native population of sub-Saharan Africa. 2. A deficiency disease caused by lack ... and 5 (b) 1, 2 and 4 (c) 1, 3 and 5 (d) 2, 3 and 5
Last Answer : a) 2, 4 and 5
Description : AIDS stands for (1) Acquired Immune Disease Syndrome (2) Acquired Immunity Deficient Syndrome (3) Acquired Immune Deficiency (4) Acquired Infection Deficiency Syndrome
Last Answer : (3) Acquired Immune Deficiency
Description : Intestinal absorption of magnesium is increased in (A) Calcium deficient diet (B) High calcium diet (C) High oxalate diet (D) High phytate diet
Description : In adrenogenital syndrome due to total absence of 21-hydroxylase in adrenal cortex, there is (A) Deficient secretion of glucocorticoids (B) Deficient secretion of mineralcorticoids (C) Excessive secretion of androgens (D) All of these
Description : Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies
Description : Diabetes insipidus is caused by deficient secretion of (A) Insulin (B) Glucagon (C) Vasopressin (D) Oxytocin
Description : The Iron deficient children, absorption of Iron from GIT is (A) Unaltered (B) Double than in normal child (C) Manifold than in normal child (D) Lesser than in normal child
Description : Haem synthetase is congenitally deficient in (A) Congenital erythropoietic porphyria (B) Protoporphyria (C) Hereditary coproporphyria (D) Variegate porphyria
Description : Enzyme deficient in Hyperammonemia type II is (A) Glutamine synthetase (B) Glutaminase (C) Ornithine transcarbamoylase (D) Carbamoylphosphate synthetase
Description : Which of the following vitamins would most likely become deficient in a person who develops a completely carnivorous life style? (A) Thiamine (B) Niacin (C) Cobalamine (D) Vitamin C
Description : The proteins present in maize are deficient in (A) Lysine (B) Threonine (C) Tryptophan (D) Tyrosine
Description : The vitamin which would most likely become deficient in an individual who develop a completely carnivorous life style is (A) Thiamin (B) Niacin (C) Vitamin C (D) Cobalamin
Description : Marasmus occurs from deficient intake of (A) Essential amino acids (B) Essential fatty acids (C) Calories (D) Zinc
Description : Kwashiorkor occurs when the diet is severely deficient in (A) Iron (B) Calories (C) Proteins (D) Essential fatty acids