Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Last Answer : Answer : B
Description : Pre- hepatic jaundice occurs because of (A) Increased haemolysis (B) Liver damage (C) Biliary obstruction (D) None of these
Last Answer : Answer : A
Description : Prothrombin time is prolonged in (A) Vitamin K deficiency (B) Liver damage (C) Both (A) and (B) (D) None of these
Last Answer : Answer : C
Description : Fecal urobilinogen is decreased in (A) Obstruction of biliary duct (B) Hemolytic jaundice (C) Excess fat intake (D) Low fat intake
Description : Fecal urobilinogen is increased in (A) Hemolytic jaundice (B) Obstruction of biliary duct (C) Extrahepatic gall stones (D) Enlarged lymphnodes
Description : In obstructive jaundice prothrombin time (A) Remains normal (B) Decreases (C) Responds to vit K and becomes normal (D) Responds to vit K and increases
Description : Prothrombin time is prolonged by administering (A) Vitamin K (B) Dicoumarol (C) Calcium (D) Prothrombin
Description : Prolonged oral therapy with the following antibiotic can damage intestinal villi resulting in steatorrhoea and loose motions: A. Ampicillin B. Tetracycline C. Neomycin D. Nystatin
Last Answer : C. Neomycin
Description : In parenhymatous liver disease the prothrombin time (A) Remains normal (B) Increases (C) Decreases (D) Responds to Vit K
Description : The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration ... warfarin be continued for at least one year after initial episode of deep venous thrombosis
Last Answer : Answer: a, b Warfarin interferes with the vitamin K dependent clotting factors II, VII, IX and X, protein C, and protein S. An important complication of warfarin is skin ... the benefit from anticoagulant therapy and thus is the basis for discontinuing warfarin administration at this time
Description : Von Willebrand's disease is a common, congenital bleeding disorder. Which of the following statement(s) is/are true concerning Von Willebrand's disease? a. As in hemophilia, it is ... -treatment for elective surgery require administration of cryoprecipitate to achieve levels of 23-50% of normal
Last Answer : Answer: c, d Von Willebrand's factor is an adhesive protein that mediates platelet adhesion to collagen. In addition, it protects and prevents the rapid removal of factor VIII ... platelet aggregation responses to ristocetin. The most reliable source of Von Willebrand's factor is cryoprecipitate
Description : Serum lipase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Infective hepatitis (D) Biliary obstruction
Description : Hypervitaminosis K in neonates may cause (A) Porphyria (B) Jaundice (C) Pellagra (D) Prolonged bleeding
Description : The transfusion of fresh frozen plasma (FFP) is indicated for which of the following reasons? A. Volume replacement. B. As a nutritional supplement. C. Specific coagulation factor deficiency ... the correction of abnormal PT secondary to warfarin therapy, vitamin K deficiency, or liver disease.
Last Answer : Answer: CD DISCUSSION: The use of FFP as a volume expander is not indicated. There are currently several preparations (both crystalloid and colloid) that are equally effective and do not carry the infectious and ... vitamin K-dependent factors II, VII, IX, and X, as well as protein C and protein S
Description : Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these
Description : Bile pigments are not present in urine in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Rotor’s syndrome
Description : kernicterus can occur in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) All of these
Description : Serum gamma glutamyl transpeptidase is raised in (A) Haemolytic jaundice (B) Myocardial infarction (C) Alcoholic hepatitis (D) Acute cholecystitis
Description : Galactose intolerance can occur in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) None of these
Description : Serum albumin: globulin ratio is altered in (A) Gilbert’s disease (B) Haemolytic jaundice (C) Viral hepatitis (D) Stones in bile duct
Description : Serum albumin may be decreased in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) All of these
Description : In haemolytic jaundice, urine shows (A) Absence of bile pigments and urobilinogen (B) Presence of bile pigments and urobilinogen (C) Absence of bile pigments and presence of urobilinogen (D) Presence of bile pigments and absence of urobilinogen FATS AND FATTY ACID METABOLISM 91
Description : Bile pigments are absent and urobilinogen increased in urine in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) Rotor’s syndrome
Description : Bile pigments are present and urobilinogen absent in urine in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) Crigler-Najjar syndrome
Description : Metabolic acidosis is caused in (A) Pneumonia (B) Prolonged starvation (C) Intestinal obstruction (D) Bulbar polio
Description : A complete absence of fecal urobilinogen is strongly suggestive of (A) Obstruction of bile duct (B) Hemolytic jaundice (C) Intrahepatic cholestasis (D) Malignant obstructive disease
Last Answer : Answer : D
Description : All the following conditions produce a real or functional deficiency of vitamin K except (A) Prolonged oral, broad spectrum antibiotic therapy (B) Total lack of red meat in the diet (C) The total lack of green leafy vegetables in the diet (D) Being a new born infant
Description : Excretion of conjugated bilirubin from liver cells into biliary canaliculi is defective in (A) Gilbert’s disease (B) Crigler-Najjar syndrome (C) Lucey-Driscoll syndrome (D) Rotor’s syndrome
Description : Which of the following statement(s) concerning laboratory studies used in monitoring a patient with intravenous heparinization is/are correct? a. The platelet count should be followed because of the ... serum creatinine should be measured daily to allow adjustments in dose based on renal function
Last Answer : Answer: a, c In monitoring the effect of heparin, an activated partial thromboplastin time (aPTT) of 1.5 control or a thrombin clotting time (TCT) of 2 times control reflects adequate ... system. Therefore the dose of heparin need not be adjusted in cases of liver or renal dysfunction
Description : The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. all above
Last Answer : all above
Description : The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. is increased by heparin
Last Answer : assess the extrinsic pathway of the blood coagulation cascade
Description : When the clearance above the obstruction is equal to the radii of even Fresnel zone at the point of reflection the RSL A. remains the same B. is above threshold C. is decreased D. is increased
Last Answer : C. is decreased
Description : Which of the following is not true about warfarin, a. INR of 3 is enough to start any extraction. b. Affects extrinsic system and increases prothrombin time. c. Heparin can be given subcutaneously ... rapidly. d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.
Last Answer : d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.
Description : Which of the following is not true about warfarin, ** A. INR of 3 is enough to start any extraction B. Affects extrinsic system and decreases prothrombin time C. Heparin can be given subcutaneously and acts rapidly D. It takes up to 12 hours for Vitamin K to reverse the effects of warfarin
Last Answer : B. Affects extrinsic system and decreases prothrombin time
Description : The specific role of Vitamin K is in the synthesis of - (1) Albumin. (2) Antibodies (3) Globulin (4) Prothrombin
Last Answer : (4) Prothrombin Explanation: Vitamin K is a necessary participant in synthesis of several proteins that mediate both coagulation and anticoagulation. It is noteworthy for the synthesis of Prothrombin ( ... in the clotting process. Vitamin K is integrally involved in the clotting mechanism of blood.
Description : Vitamin K is required for (a) change of prothrombin into thrombin (b) synthesis of prothrombin (c) change of fibrinogen to fibrin (d) formation of thromboplastin.
Last Answer : (b) synthesis of prothrombin
Description : The specific role of Vitamin K is in the synthesis of (1) Albumin (2) Antibodies (3) Globulin (4) Prothrombin
Last Answer : Prothrombin
Description : A test to evaluate detoxifying function of liver is (A) Serum albumin: globulin ratio (B) Galactose tolerance test (C) Hippuric acid test (D) Prothrombin time
Description : Which of the following statements are true of the multiple organ dysfunction syndrome (MODS)? A. The two-hit model proposes that secondary MODS may be produced when even a relatively ... intensive care units has decreased owing to increased awareness, prevention, and treatment of the syndrome.
Last Answer : Answer: ABC DISCUSSION: MODS is part of a clinical continuum that begins with the systemic inflammatory response syndrome, which is the host's stress response to any major insult such ... pathogenesis of MODS, the incidence of MODS continues to increase without a significant improvement in outcome
Description : Prothrombin is synthesised in (A) Erythrocytes (B) Reticulo-endothelial cells (C) Liver (D) Kidneys
Description : Vitamin K is indicated for the treatment of bleeding occurring in patients: A. Being treated with heparin B. Being treated with streptokinase C. Of obstructive jaundice D. Of peptic ulcer
Last Answer : C. Of obstructive jaundice
Description : The presence of bilirubin in the urine without urobilinogen suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Pernicious anemia (D) Damage to the hepatic parenchyma
Description : An early effect of vitamin a deficiency is (A) Xerophthalmia (B) Keratomalacia (C) Prolonged dark adaptation time (D) Follicular hyperkeratosis
Description : Inhibitors of prostaglandin synthesis share the following features except: A. Prolongation of bleeding time B. Prolongation of prothrombin time C. Prolongation of labour D. Gastric mucosal damage
Last Answer : B. Prolongation of prothrombin time
Description : Indications of somatostatin include: A. Macroprolactinoma B. Zollinger Ellison syndrome C. Bleeding esophageal varices D. Steatorrhoea
Last Answer : C. Bleeding esophageal varices
Description : Do car magnets damage paint after prolonged use?
Last Answer : Car magnets are completely safe to use on a car. The metal of the magnet does not interact with the paint of the car. Car magnets are specifically designed to be placed on a car with no damage.
Description : Kehr’s sign is a classical feature of Options: 1) Rupture of liver 2) Acute pancreatitis 3) Acute intestinal obstruction 4) Rupture of spleen
Last Answer : Correct Answer: 4) Rupture of spleen
Description : Prophylactic administration of Vitamin K in breast fed babies is an example of A A. Specific protection B. Health promotion C. Rehabilitation D. Primordial
Last Answer : . Specific protection