Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Last Answer : Answer : B
Description : A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice
Description : Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these
Last Answer : Answer : C
Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT
Last Answer : Answer : D
Description : A mixture of conjugated and unconjugated bilirubin is found in the circulation in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Post hepatic jaundice
Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency
Last Answer : Answer : A
Description : If results of the serum bilirubin, serum ALP, LDH and AST determinations suggest obstructive jaundice, the best confirmatory test would be the estimation of (A) Serum ALT (B) Serum 5’ nucleotidase (C) Serum Pseudo cholinesterase (D) None of these
Description : An increase in serum unconjugated bilirubin occurs in (A) Hemolytic jaundice (B) Obstructive jaundice (C) Nephritis (D) Glomerulonephritis
Description : Bile pigments are not present in urine in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Rotor’s syndrome
Description : Bile pigments are present and urobilinogen absent in urine in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) Crigler-Najjar syndrome
Description : The presence of bilirubin in the urine without urobilinogen suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Pernicious anemia (D) Damage to the hepatic parenchyma
Description : Increased urobilinogen in urine and absence of bilirubin in the urine suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Viral hepatitis (D) Toxic jaundice
Description : In obstructive jaundice, urine shows (A) Absence of bile pigments and urobilinogen (B) Presence of bile pigments and urobilinogen (C) Absence of bile pigments and presence of urobilinogen (D) Presence of bile pigments and absence of urobilinogen
Description : Bile pigments are absent and urobilinogen increased in urine in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) Rotor’s syndrome
Description : In obstructive jaundice, urinary bilirubin is (A) Absent (B) Increased (C) Present (D) Present in small amount
Description : The normal range of direct reacting (conjugated) serum bilirubin is (A) 0–0.1 mg/100 ml (B) 0.1–0.4 mg/100 ml (C) 0.4–06 mg/100 ml (D) 0.5–1 mg/100 ml
Description : Which of the following is true of Gilbert's syndrome? 1) inheritance is autosomal recessive 2) serum conjugated bilirubin levels are elevated 3) serum bilirubin levels are decreased by fasting 4) serum bilirubin levels are decreased by liver enzyme inducers 5) there is bilirubinuria
Last Answer : Answers-4 Gilbert's syndrome is inherited in autosomal dominant fashion and affects 2-5% of the population. UDP glucuronyl transferase levels are reduced leading to an unconjugated hyperbilirubinaemia. ... the bilirubin is reabsorbed in the proximal tubule some bilirubin is detectable in the urine.
Description : In hemolytic jaundice, bilirubin in urine is (A) Usually absent (B) Usually present (C) Increased very much (D) Very low
Description : It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?
Last Answer : ALP level is increased in both liver and bone diseases, but NTP is only in liver diseases.
Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase
Description : The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml
Description : A complete absence of fecal urobilinogen is strongly suggestive of (A) Obstruction of bile duct (B) Hemolytic jaundice (C) Intrahepatic cholestasis (D) Malignant obstructive disease
Description : Serum concentration is increased when destruction of erythrocytes is increased A A. Unconjugated bilirubin B. Conjugated bilirubin C. Both D. None of these
Last Answer : Unconjugated bilirubin
Description : Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT
Description : Patients with hepatocellular jaundice, as compared to those with purely obstructive jaundice tend to have (A) Lower serum ALP, LDH and AST activity (B) Lower serum ALP, Higher LDH and AST activity (C) Higher serum ALP, LDH and AST activity (D) Higher serum ALP, Lower LDH and AST activity
Description : Serum albumin may be decreased in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) All of these
Description : Jaundice is visible when serum bilirubin exceeds (A) 0.5 mg/100 ml (B) 0.8 mg/100 ml (C) 1 mg/100 ml (D) 2.4 mg/100 ml
Description : Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome
Description : In hemolytic jaundice, the urinary bilirubin is (A) Normal (B) Absent (C) More than normal (D) Small amount is present
Description : Reviewing the laboratory findings of the client, the nurse would found which findings are elevated? 1. White blood cell count 2. Total serum bilirubin 3. Alkaline phosphate 4. Red blood cell count 5. Cholesterol 6. Serum amylase A. 1, 2, and 3 B. 2, 3, and 4 C. 3, 5, and 6 D. 1, 2, and 6
Last Answer : A. 1, 2, and 3
Description : Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits ... biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure
Last Answer : Answers-2 Osteomalacia is associated with low calcium and phosphate with raised alkaline phosphatase. Serum biochemistry is normal in osteoporosis. Pagets disease is associated with normal ... renal failure when tertiary hyperparathyroidism sets in there is low calcium with raised phosphate.
Description : Alkaline phosphatase level in serum is elevated in which conditions?
Last Answer : Moderate increase is seen in hepatic diseases (infective hepatitis, alcoholic hepatitis). High levels may be noticed in obstructive jaundice or cholestasis. Very high levels are seen in bone diseases such as Pagetís disease, rickets, osteomalacia, osteoblastoma, metastatic carcinoma of bone.
Description : Serum albumin: globulin ratio is altered in (A) Gilbert’s disease (B) Haemolytic jaundice (C) Viral hepatitis (D) Stones in bile duct
Description : The normal range of total serum bilirubin is (A) 0.2–1.2 mg/100 ml (B) 1.5–1.8 mg/100 ml (C) 2.0–4.0 mg/100 ml (D) Above 7.0 mg/100 ml
Description : Serum gamma glutamyl transpeptidase is raised in (A) Haemolytic jaundice (B) Myocardial infarction (C) Alcoholic hepatitis (D) Acute cholecystitis
Description : In haemolytic jaundice, urine shows (A) Absence of bile pigments and urobilinogen (B) Presence of bile pigments and urobilinogen (C) Absence of bile pigments and presence of urobilinogen (D) Presence of bile pigments and absence of urobilinogen FATS AND FATTY ACID METABOLISM 91
Description : In obstructive jaundice, faecal urobilinogen is (A) Absent (B) Decreased (C) Increased (D) Normal
Description : In obstructive jaundice prothrombin time (A) Remains normal (B) Decreases (C) Responds to vit K and becomes normal (D) Responds to vit K and increases
Description : Excretion of conjugated bilirubin from liver cells into biliary canaliculi is defective in (A) Gilbert’s disease (B) Crigler-Najjar syndrome (C) Lucey-Driscoll syndrome (D) Rotor’s syndrome
Description : All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase
Description : The normal range of indirect (unconjugated) bilirubin in serum is (A) 0–0.1 mg/100 ml (B) 0.1–0.2 mg/100 ml (C) 0.2–0.7 mg/100 ml (D) 0.8–1.0 mg/100 ml
Description : Alkaline phosphatase is present in (A) Liver (B) Bones (C) Intestinal mucosa (D) All of these
Description : Alkaline phosphatase is present in (A) Liver (B) Bones (C) Placenta (D) All of these
Description : For alkaline phosphatase, how many iso-enzymes are present?
Last Answer : Six.
Description : The normal serum acid phosphatase activity ranges from (A) 5.0–13.0 KA units/100 ml (B) 1.0–5.0 KA units/100 ml (C) 13.0–18.0 KA units/100 ml (D) 0.2–0.8 KA units/100 ml
Description : Markedly increased concentration responsible for kernicterus in hemolytic disease of the newborn. A A. Unconjugated bilirubin B. Conjugated bilirubin C. Both D. None of these
Description : kernicterus can occur in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) All of these
Description : Hypocholesterolemia is found in (A) Thyrotoxicosis (B) Diabetes mellitus (C) Obstructive jaundice (D) Nephrotic syndrome
Description : Galactose intolerance can occur in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) None of these
Description : Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89