Description : Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow
Last Answer : Answer : D
Description : Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow
Last Answer : Answer : B
Description : Renal glycosuria occurs due to (A) Increased filtration of glucose in glomeruli (B) Increased secretion of glucose by renal tubular cells (C) Decreased reabsorption of glucose by renal tubular cells (D) Increased conversion of glycogen into glucose in tubular cells
Description : In studies of the human body, which of the following terms is used to describe the first step in the production of urine? Is it: a) tubular secretion b) tubular reabsorption c) glomerular filtration d) none of these
Last Answer : ANSWER: C -- GLOMERULAR FILTRATION
Description : Measurement of inulin renal clearance is a measure for (A) Effective renal blood flow (B) Renal drug excretion rate (C) Active renal secretion (D) Glomerular filtration rate
Last Answer : (D) Glomerular filtration rate
Description : The most important channel of elimination of digoxin is: A. Glomerular filtration B. Tubular secretion C. Hepatic metabolism D. Excretion in bile
Last Answer : A. Glomerular filtration
Description : If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation
Last Answer : A. More than the glomerular filtration rate
Description : Creatinine EDTA clearance is a test to measure (A) Renal plasma flow (B) Filtration fraction (C) Glomerular filtration rate (D) Tubular function
Last Answer : Answer : C
Description : Measurement of insulin clearance test is a measure of (A) Glomerular filtration rate (B) Filtration factor (C) Renal plasma flow (D) Tubular secretory mass
Last Answer : Answer : A
Description : Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass
Description : An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine
Description : The Tm for PAH i.e the maximal secretory capacity of the tubule for PAH can be used to gavge the (A) Extent of tubular damage FATS AND FATTY ACID METABOLISM 81 (B) Impairment of the capacity of the tubule to perform osmotic work (C) Impairment of renal plasma flow (D) Glomerular filtration rate
Description : Which one of the following correctly explains the function of a specific part of the human nephron? (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the ... blood capillaries (d) Afferent arteriole : carries the blood away from the glomerulus towards renal vein.
Last Answer : (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the Bowman’s capsule
Description : Interindividual variations in equieffective doses of a drug are most marked if it is disposed by: A. Glomerular filtration B. Tubular secretion C. Both glomerular filtration and tubular secretion D. Hepatic metabolism
Last Answer : D. Hepatic metabolism
Description : Glomerular filtration of a drug is affected by its: A. Lipid solubility B. Plasma protein binding C. Degree of ionization D. Rate of tubular secretion
Last Answer : B. Plasma protein binding
Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase
Description : Which of the following concerning the pH of urine is correct? 1) is a useful indicator of the acid/base balance of the blood 2) rises on a vegetarian diet 3) is determined by the concentration of ... lower than 5.5 in renal tubular acidosis 5) would be above 7.0 after prolonged and severe vomiting
Last Answer : Answers-2 c - excretion of ammonium occurs when an acid urine is produced but the pH of urine is of course determined by the concentration of H+ ions d-unable to lower the pH to ... and distal nephron and this perpetuates the metabolic alkalosis until the fluid balance is restored with IV fluids.
Description : The plasma half life of pencillin-G is longer in the new born because their (a) Plasma protein level is low (b) Drug metabolizing enzymes are immature (c) Glomerular filtration rate is low (d) Tubular transport mechanisms are not well developed
Last Answer : Ans: D
Description : The plasma half life of penicillin-G is longer in the new born because their: A. Plasma protein level is low B. Drug metabolizing enzymes are immature C. Glomerular filtration rate is low D. Tubular transport mechanisms are not well developed
Last Answer : D. Tubular transport mechanisms are not well developed
Description : Renal ricket is caused by renal tubular defect (usually inherited) which interferes with reabsorption of (A) Calcium (B) Phosphorous (C) Sodium (D) Chloride
Description : The most important effect of aldosterone is to (A) Increase the rate of tubular reabsorption of sodium (B) Decrease the rate of tubular reabsorption of potassium (C) Decrease the reabsorption of chloride (D) Decrease the renal reabsorption of sodium
Description : Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis
Description : Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective ... 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+
Last Answer : Answers-2 H+ secretion, sodium reabsorption and ammonia production diminishes. RTA 4 is in effect hyporeninaemic hypoaldosteronism or failure of aldosterone action and thus helped treated with ... particularly. Aminoaciduria and increased urine bicarbonate are features of RTA types 1 and 2.
Description : The most important reason for the thiazides being only moderately efficacious diuretics is: A. About 9/10th of glomerular filtrate is reabsorbed proximal to their site of action B. Compensatory ... these drugs C. They decrease glomerular filtration D. They have relatively flat dose response curve
Last Answer : A. About 9/10th of glomerular filtrate is reabsorbed proximal to their site of action
Description : An early feature of renal disease is (A) Impairment of the capacity of the tubule to perform osmotic work (B) Decrease in maximal tubular excretory capacity (C) Decrease in filtration factor (D) Decrease in renal plasma flow
Last Answer : A
Description : Which of the following factors is responsible for the formation of concentrated urine? (a) Hydrostatic pressure during glomerular filtration. (b) Low levels of antidiuretic hormone. (c) ... the medullary interstitium in the kidneys. (d) Secretion of erythropoietin by Juxtaglomerular complex.
Last Answer : (c) Maintaining hyperosmolarity towards the medullary interstitium in the kidneys.
Description : The primary mechanism by which antidiuretic hormone reduces urine volume is: A. Decrease in glomerular filtration rate B. Decreased renal blood flow C. Decreased water permeability of descending limb of loop of Henle D. Increased water permeability of collecting duct cells
Last Answer : D. Increased water permeability of collecting duct cells
Description : The pharmacokinetics of drugs in the neonate differs from that in adults, because their: A. Intestinal transit is fast B. Drug metabolizing enzymes are overactive C. Tubular transport mechanisms are not well developed D. Glomerular filtration rate is high
Last Answer : C. Tubular transport mechanisms are not well developed
Description : Excretion of phenolsulphanpthalein (PSP) reflects (A) Glomerulonephritis (B) Maximaltabular excretory capacity (C) Filtration factor (D) Renal plasma flow
Description : The following are true about aldosterone: a. it is secreted by the adrenal medulla b. its secretion is stimulated by decreased blood volume c. it stimulates active reabsorption of sodium in the distal renal tubules. d. it causes increased secretion of potassium by the distal renal tubules.
Last Answer : it causes increased secretion of potassium by the distal renal tubules.
Description : During compensation of respiratory alkalosis, all the following changes occur except (A) Decreased secretion of hydrogen ions by renal tubules (B) Increased excretion of sodium in urine (C) Increased excretion of bicarbonate in urine (D) Increased excretion of ammonia in urine
Description : Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by: A. Inducing synthesis of Na+K+ATPase B. Inducing synthesis of amiloride sensitive Na+ channels C. Translocating Na+ channels from cytosolic site to luminal membrane D. All of the above
Last Answer : D. All of the above
Description : Which one of the following statements in regard to the excretion by the human kidneys is correct? (a) Descending limb of loop of Henle is impermeable to water. (b) Distal convoluted tubule is ... reabsorbed by the renal tubules. (d) Ascending limb of loop of Henle is impermeable to electrolytes.
Last Answer : (c) Nearly 99 per cent of the glomerular filtrate is reabsorbed by the renal tubules.
Description : Which of the following would help in prevention of diuresis? (a) More water reabsorption due to undersecretion of ADH. (b) Reabsorption of Na+ and water from renal tubules due to ... Atrial natriuretic factor causes vasoconstriction. (d) Decrease in secretion of renin by JG cells. (NEE
Last Answer : (b) Reabsorption of Na+ and water from renal tubules due to aldosterone.
Description : Among the following, a test of Glomerular function is (A) Urea clearance (B) PSP excretion test (C) PAH clearance (D) Hippuric acid excretion test
Description : Glomerular filtration rate can be measured by (A) Endogenous creatinine clearance (B) Para-aminohippurate test (C) Addis test (D) Mosenthal test
Description : Among the following, a test of tubular function is (A) Creatinine clearance (B) Inulin clearance (C) PAH clearance (D) PSP excretion test
Description : The blood sugar raising action of the hormone of suprarenal cortex is due to (A) Glyconeogenesis (B) Glycogenolysis (C) Glucagon like activity (D) due to inhibition of glomerular filtration of glucose
Description : The blood sugar raising action of the hormones of suprarenal cortex is due to (A) Gluconeogenesis (B) Glycogenolysis (C) Glucagon-like activity (D) Due to inhibition of glomerular filtration
Description : 06. A hydrophilic medicinal agent has the following property: a) Low ability to penetrate through the cell membrane lipids b) Penetrate through membranes by means of endocytosis c) Easy permeation through the blood-brain barrier d) High reabsorption in renal tubules
Last Answer : a) Low ability to penetrate through the cell membrane lipids
Description : Obligatory reabsorption of water (A) Is about 50% of the total tubular reabsorption of water (B) Is increased by antidiuretic hormone (C) Occurs in distal convoluted tubules (D) Is secondary to reabsorption of solutes
Description : Mineralocorticoids increase the tubular reabsorption of (A) Sodium and calcium (B) Sodium and potassium (C) Sodium and chloride (D) Potassium and chloride 224 MCQs IN BIOCHEMISTRY
Description : Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose
Description : PTH causes all of the following except (A) Increased intestinal absorption of calcium (B) Increased intestinal absorption of phosphate (C) Increased tubular reabsorption of calcium (D) Increased tubular reabsorption of phosphate
Description : Tubular reabsorption of calcium is increased by (A) Cholecalciferol (B) 25-Hydroxycholecalciferol (C) Calcitriol (D) All of these