A soluble system for synthesis of fatty acids have been isolated from avian liver, required for the formation of long chain fatty acids by this system is (A) ATP (B) Acetyl CoA (C) NADPH (D) All of these

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Answer : D

Related questions

Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these

Last Answer : Answer : D

Description : In the extra mitochondrial synthesis of fatty acids, CO2 is utilized (A) To keep the system anaerobic and prevent regeneration of acetyl CoA (B) In the conversion of malonyl to CoA hydroxybutyryl CoA (C ... of acetyl CoA to malonyl CoA (D) In the formation of acetyl CoA from 1 carbon intermediates

Last Answer : Answer : C

Description : β-oxidation of fatty acids is inhibited by (A) NADPH (B) Acetyl CoA (C) Malonyl CoA (D) None of these

Last Answer : Answer : C

Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form

Last Answer : Answer : B

Description : Acetyl CoA required for de novo synthesis of fatty acids is obtained from (A) Breakdown of existing fatty acids (B) Ketone bodies (C) Acetate (D) Pyruvate

Last Answer : Answer : D

Description : The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to (A) CO2 and water (B) Cholesterol (C) Fatty acids (D) Ketone bodies

Last Answer : Answer : A

Description : All long chain fatty acids with even number of carbon atoms are oxidized to a pool of _________ by β-oxidation. (A) CO2 (B) Propionic acid (C) Acetic acid (D) Acetyl CoA

Last Answer : Answer : D

Description : Long chain fatty acids are first activated to acetyl-CoA in (A) Cytosol (B) Microsomes (C) Nucleus (D) Mitochondria

Last Answer : Answer : A

Description : Acetyl CoA formed from pyruvate can be used for the synthesis of all the following except (A) Glucose (B) Fatty acids (C) Cholesterol (D) Steroid hormones

Last Answer : Answer : A

Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,

Last Answer : Answer : B

Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity

Last Answer : Answer : A

Description : Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible: (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1, 6 diphosphate to ... phosphate (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids

Last Answer : Answer : C

Description : Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible. (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1,6-bisphosphate to fructose- ... (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids

Last Answer : C

Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP

Last Answer : Answer : A

Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase

Last Answer : Answer : B

Description : As a result of each oxidation a long chain fatty acid is cleaved to give (A) An acid with 3-carbon less and propionyl CoA (B) An acid with 2-carbon less and acetyl CoA (C) An acid with 2-carbon less and acetyl CoA (D) An acid with 4-carbon and butyryl CoA

Last Answer : Answer : B

Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex

Last Answer : Answer : B

Description : Which of the following cofactors or their derivatives must be present for the conversion of acetyl CoA to malonyl CoA extramitochondrial fatty acid synthesis? (A) Biotin (B) FAD (C) FMN (D) ACP

Last Answer : Answer : A

Description : For extramitochondrial fatty acid synthesis, acetyl CoA may be obtained from (A) Citrate (B) Isocitrate (C) Oxaloacetate (D) Succinate

Last Answer : Answer : A

Description : Acetyl CoA carboxylase regulates fatty acid synthesis by which of the following mechanism? (A) Allosteric regulation (B) Covalent modification (C) Induction and repression (D) All of these

Last Answer : Answer : D

Description : Acetyl CoA is not used for the synthesis of (A) Fatty acid (B) Cholesterol (C) Pyruvic acid (D) Citric acid

Last Answer : C

Description : Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?

Last Answer : ATP citrate lyase.

Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis

Last Answer : Answer : A

Description : β-Oxidation of odd-carbon fatty acid chain produces (A) Succinyl CoA (B) Propionyl CoA (C) Acetyl CoA (D) Malonyl CoA

Last Answer : Answer : D

Description : Acetyl-CoA can be formed from (A) Pyruvate (B) Fatty acids (C) ketone bodies (D) All of these

Last Answer : Answer : D

Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase

Last Answer : Answer : C

Description : Fatty acids with odd number of carbon atoms yield acetyl-CoA and a molecule of (A) Succinyl-CoA (B) Propionyl-CoA (C) Malonyl-CoA (D) Acetoacetyl-CoA

Last Answer : Answer : B

Description : Propionyl CoA formed oxidation of fatty acids having an odd number of carbon atoms is converted into (A) Acetyl CoA (B) Acetoacetyl CoA (C) D-Methylmalonyl CoA (D) Butyryl CoA

Last Answer : Answer : C

Description : The synthesis of fatty acids is often termed reductive synthesis. (A) NADP+ (B) NADH (C) FADH2 (D) NADPH

Last Answer : Answer : D

Description : Mitochondrial lipogenesis requires (A) bicarbonate (B) biotin (C) acetyl CoA carboxylase (D) NADPH

Last Answer : Answer : D

Description : A pathway that requires NADPH as a cofactor is (A) Fatty acid oxidation (B) Extra mitochondrial denovo fatty acid synthesis (C) Ketone bodies formation (D) Glycogenesis

Last Answer : Answer : B

Description : Carnitine is required for the transport of (A) Triglycerides out of liver (B) Triglycerides into mitochondria (C) Short chain fatty acids into mitochondria (D) Long chain fatty acids into mitochondria

Last Answer : Answer : D

Description : Long chain fatty acids are first activated to acyl CoA in the (A) Cytosol (B) Mitochodria (C) Ribosomes (D) Microsome

Last Answer : Answer : A

Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier

Last Answer : Answer : C

Description : This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP: (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thio kinase

Last Answer : Answer : D

Description : During which stage in the complete oxidation of glucose are the greatest number of ATP molecules formed from ADP? (a) Glycolysis (b) Krebs’ cycle (c) Conversion of pyruvic acid to acetyl CoA (d) Electron transport chain

Last Answer : (d) Electron transport chain

Description : NADPH required for fatty acid synthesis can come from (A) Hexose monophosphate shunt (B) Oxidative decarboxylation of malate (C) Extramitochondrial oxidation of isocitrate (D) All of these

Last Answer : Answer : D

Description : Which of the following is required as a reductant in fatty acid synthesis? (A) NADH (B) NADPH (C) FADH2 (D) FMNH2

Last Answer : Answer : B

Description : C22 and C24, fatty acids required for the synthesis of sphingolipids in brain are formed by (A) De novo synthesis (B) Microsomal chain elongation (C) Mitochondrial chain elongation (D) All of these

Last Answer : Answer : B

Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate

Last Answer : Answer : A

Description : An enzyme required for the synthesis of ketone bodies as well as cholesterol is (A) Acetyl CoA carboxylase (B) HMG CoA synthetase (C) HMG CoA reductase (D) HMG CoA lyase

Last Answer : Answer : B

Description : Synthesis of polyunsaturated fatty acids involves the enzyme systems: (A) Acyl transferase and hydratase (B) Desaturase and elongase (C) Ketoacyl-CoA reductase and hydratase (D) Dihydroxyacetone phosphate

Last Answer : Answer : A

Description : De novo synthesis of fatty acids requires all of the following except (A) Biotin (B) NADH (C) Panthothenic acid (D) ATP

Last Answer : Answer : D

Description : An allosteric inhibitor of pyruvate dehydrogenase is (A) Acetyl CoA (B) ATP (C) NADH (D) Pyruvate

Last Answer : Answer : A

Description : Oxidative degradation of acetyl CoA in the citric acid cycle gives a net yield of all the following except (A) FADH2 (B) 3 NADH (C) 2 ATP (D) 2CO2

Last Answer : Answer : C

Description : Which of the following compound is a positive allosteric modifier of the enzyme pyruvate carboxylase? (A) Biotin (B) Acetyl CoA (C) Oxaloacetate (D) ATP

Last Answer : A

Description : The number of molecules of ATP produced by the total oxidation of acetyl CoA in TCA cycle is (A) 6 (B) 8 (C) 10 (D) 12

Last Answer : D

Description : All statements regarding 3-OH-3 methyl glutaryl CoA are true except (A) It is formed in the cytoplasm (B) Required in ketogenesis (C) Involved in synthesis of Fatty acid (D) An intermediate in cholesterol biosynthesis

Last Answer : Answer : B

Description : The number of milliliters of 0.1 N KOH required to neutralize the insoluble fatty acids from 5 gms of fat is called (A) Acid number (B) Acetyl number (C) Halogenation (D) Polenske number

Last Answer : Answer : D

Description : The number of ml of N/10 KOH required to neutralize the fatty acids in the distillate from 5 gm of fat is called (A) Reichert-Meissel number (B) Polenske number (C) Acetyl number (D) Non volatile fatty acid number

Last Answer : Answer : A