Description : Activated lecithin cholesterol acyl transferase is essential for the conversion of (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2
Last Answer : Answer : B
Description : Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by (A) cAMP (B) Prostaglandin (C) Carnitine (D) Choline
Last Answer : Answer : C
Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity
Last Answer : Answer : A
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase
Description : Lesch-Nyhan syndrome, the sex linked recessive disorder is due to the lack of the enzyme: (A) Hypoxanthine-guanine phosphoribosyl transferse (B) Xanthine oxidase (C) Adenine phosphoribosyl transferase (D) Adenosine deaminase
Description : When choline of lecithin is replaced by ethanolamine, the product is (A) Spingomyelin (B) Cephalin (C) Plasmalogens (D) Lysolecithin
Description : Carnitine is synthesized from (A) Lysine (B) Serine (C) Choline (D) Arginine
Description : Lecithin contains a nitrogenous base named as (A) Ethanolamine (B) Choline (C) Inositol (D) All of these
Description : Lysolecithin is formed from lecithin by removal of (A) Fatty acid from position 1 (B) Fatty acid from position 2 (C) Phosphorylcholine (D) Choline
Description : The nitrogenous base in lecithin is (A) Ethanolamine (B) Choline (C) Serine (D) Betaine
Description : In synthesis of Triglyceride from α-Glycero phosphate and acetyl CoA, the first intermediate formed is (A) β-diacyl glycerol (B) Acyl carnitine (C) Monoacyl glycerol(D) Phosphatidic acid
Last Answer : Answer : D
Description : Long chain acyl CoA penetrates mitochondria in the presence of (A) Palmitate (B) Carnitine (C) Sorbitol (D) DNP
Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier
Description : Orotic aciduria type I reflects the deficiency of enzymes: (A) Orotate phosphoribosyl transferase and orotidylate decarboxylase (B) Dihydroorotate dehydrogenase (C) Dihydroorotase (D) Carbamoyl phosphate synthetase
Description : Synthesis of phosphatidylinositol by transfer of inositol to CDP diacylglycerol is catalysed by the enzyme: (A) CTP phosphatidate cytidyl transferase (B) Phosphatidate phosphohydrolase (C) CDP-diacylglycerol inositol transferase (D) Choline kinase
Description : In abetalipoproteinemia, the biochemical defect is in (A) Apo-B synthesis (B) Lipprotein lipase activity (C) Cholesterol ester hydrolase (D) LCAT activity
Description : Erythromycin binds to 50 S ribosomal sub unit and (A) Inhibits binding of amino acyl tRNA (B) Inhibits Peptidyl transferase activity (C) Inhibits translocation (D) Causes premature chain termination
Description : Peptidyl transferase activity is present in (A) 40 S ribosomal subunit (B) 60 S ribosomal subunit (C) eEF-2 (D) Amino acyl tRNA
Description : The α-amino group of the new amino acyl tRNA in the A site carries out a nucleophilic attack on the esterified carboxyl group of the peptidyl tRNA occupying the P site. This reaction is catalysed by (A) DNA polymerase (B) RNA polymerase (C) Peptidyl transferase (D) DNA ligase
Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex
Description : Synthesis of polyunsaturated fatty acids involves the enzyme systems: (A) Acyl transferase and hydratase (B) Desaturase and elongase (C) Ketoacyl-CoA reductase and hydratase (D) Dihydroxyacetone phosphate
Description : The best known cause of galactosemia is the deficiency of (A) Galactose 1-phosphate and uridyl transferase (B) Phosphoglucomutase (C) Galactokinase (D) Lactose synthase
Description : Following enzyme is involved in the synthesis of actylcholine (a) Choline acetyl transferase (b) Acetyl cholinesterase (c) Both (a) and (b) (d) None of the above
Last Answer : Ans: A
Description : A synthetic RNA having the sequence of UUUUUU (Poly U) will give a protein having poly ______. (A) Alamine (B) Phenyl alanine (C) Glycine (D) Methionine
Description : The first amino acid incorporated in a polypeptide in a ribosome of a bacterium is (A) N formyl methionine (B) Methionine (C) Alamine (D) Glycine
Description : Identify the substances having glycosidic bond and peptide bond, respectively in their structure. (a) Chitin, cholesterol (b) Glycerol, trypsin (c) Cellulose, lecithin (d) Inulin, insulin
Last Answer : (d) Inulin, insulin
Description : In the biosynthesis of cholesterol, the rate limiting enzyme is (A) Mevalonate kinase (B) HMG-CoA synthetase (C) HMG-CoA reductase (D) Cis-prenyl transferase
Description : LCAT activity is associated with which of the lipo-protein complex? (A) VLDL (B) Chylomicrones (C) IDL (D) HDL
Description : The apolipoprotein which acts as activator of LCAT is (A) A-I (B) A-IV (C) C-II (D) D
Description : The lipoprotein associated with activation of LCAT is (A) HDL (B) LDL (C) VLDL (D) IDL
Description : What is LCAT?
Last Answer : The free cholesterol is esterified by LCAT the esterified cholesterol is then incorporated into HDL disc, to form mature HDL. So for excretion of cholesterol, LCAT is necessary.
Description : All the following compounds are members of the electron transport chain except (A) Ubiquinone (B) Carnitine (C) NAD (D) FAD
Description : Which of the following is not a phospholipids? (A) Lecithin (B) Plasmalogen (C) Lysolecithin (D) Gangliosides
Description : Phospholipase A2 is an enzyme which removes a fatty acid residue from lecithin to form (A) Lecithin fragments (B) Phosphotidic acid (C) Glyceryl phosphate (D) Lysolecithin
Description : Lysolecithin is formed from lecithin by the action of (A) Phospholipase A1 (B) Phospholipase A2 (C) Phospholipase C (D) Phospholipase D
Description : Which one of the following is not a phospholipid? (A) Lecithin (B) Plasmalogen (C) Lysolecithin (D) Gangliosides
Description : Carnitine acylcarnitine translocase is present (A) In the inner mitochondrial membrane (B) In the mitochondrial matrix (C) On the outer surface of inner mitochondrial membrane (D) On the inner surface of inner mitochondrial membrane
Description : Carnitine is required for the transport of (A) Triglycerides out of liver (B) Triglycerides into mitochondria (C) Short chain fatty acids into mitochondria (D) Long chain fatty acids into mitochondria
Description : Activation of fatty acids requires all the following except (A) ATP (B) Coenzyme A (C) Thiokinase (D) Carnitine
Description : Dipalmitoyl lecithin acts as (A) Platelet activating factor (B) Second messenger for hormones (C) Lung surfactant (D) Anti-ketogenic compound
Description : All the following statements about carnitine are true except (A) It can be synthesised in the human body (B) It can be synthesized from methionine and lysine (C) It is required for transport of short chain fatty acids into mitochondria (D) Its deficiency can occur due to haemodialysis
Description : Carnitine is synthesized from (A) Lysine and methionine (B) Glycine and arginine (C) Aspartate and glutamate (D) Proline and hydroxyproline
Description : Phospholipid acting as surfactant is (A) Cephalin (B) Phosphatidyl inositol (C) Lecithin (D) Phosphatidyl serine
Description : What is Lecithin?
Last Answer : Phosphatidyl choline.
Description : What is the function of carnitine?
Last Answer : Fatty acids are activated in the cytoplasm, but the beta-oxidation is in mitochondria. The long chain fatty acyl CoA cannot pass through the inner mitochondrial membrane. Therefore a transporter, carnitine is involved in transfer of fatty acids.
Description : What is carnitine?
Last Answer : Carnitine is beta-hydroxy-gamma-trimethyl ammonium butyrate. It is synthesised from lysine and methionine in liver and kidney.
Description : Two nitrogen of the pyrimidines ring are obtained from (A) Glutamine and Carbamoyl-p (B) Asparate and Carbamoyl-p (C) Glutamate and NH3 (D) Glutamine and NH3
Description : A key substance in the committed step of pyrimidines biosynthesis is (A) Ribose-5-phosphate (B) Carbamoyl phosphate (C) ATP (D) Glutamine