All the following correctly describe the intermediate 3-OH-3-methyl glutaryl CoA except (A) It is generated enzymatically in the mitochondrial matrix (B) It is formed in the cytoplasm (C) It inhibits the first step in cholesterol synthesis (D) It is involved in the synthesis of ketone bodies

1 Answer

Answer :

Answer : C

Related questions

Description : All statements regarding 3-OH-3 methyl glutaryl CoA are true except (A) It is formed in the cytoplasm (B) Required in ketogenesis (C) Involved in synthesis of Fatty acid (D) An intermediate in cholesterol biosynthesis

Last Answer : Answer : B

Description : All the following statements correctly describe ketone bodies except (A) They may result from starvation (B) They are present at high levels in uncontrolled diabetes (C) They include—OH β-butyrate and acetone (D) They are utilized by the liver during long term starvation

Last Answer : Answer : D

Description : An enzyme required for the synthesis of ketone bodies as well as cholesterol is (A) Acetyl CoA carboxylase (B) HMG CoA synthetase (C) HMG CoA reductase (D) HMG CoA lyase

Last Answer : Answer : B

Description : The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to (A) CO2 and water (B) Cholesterol (C) Fatty acids (D) Ketone bodies

Last Answer : Answer : A

Description : A pathway that requires NADPH as a cofactor is (A) Fatty acid oxidation (B) Extra mitochondrial denovo fatty acid synthesis (C) Ketone bodies formation (D) Glycogenesis

Last Answer : Answer : B

Description : Acetoacetyl-CoA condenses with one more molecule of acetyl-CoA to form (A) Mevalonate (B) Acetoacetate (C) β-Hydroxybutyrate (D) 3-Hydroxy 3-methyl-glutaryl-CoA

Last Answer : Answer : D

Description : In the pathway leading to biosynthesis of acetoacetate from acetyl-CoA in liver, the immediate precursor of aceotacetate is (A) Acetoacetyl-CoA (B) 3-Hydroxybutyryl-CoA (C) 3-Hydroxy-3-methyl-glutaryl-CoA (D) 3-Hydroxybutyrate

Last Answer : Answer : A

Description : Acetyl CoA required for de novo synthesis of fatty acids is obtained from (A) Breakdown of existing fatty acids (B) Ketone bodies (C) Acetate (D) Pyruvate

Last Answer : Answer : D

Description : Acetyl-CoA can be formed from (A) Pyruvate (B) Fatty acids (C) ketone bodies (D) All of these

Last Answer : Answer : D

Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form

Last Answer : Answer : B

Description : Acetyl CoA formed from pyruvate can be used for the synthesis of all the following except (A) Glucose (B) Fatty acids (C) Cholesterol (D) Steroid hormones

Last Answer : Answer : A

Description : All of the following statements about the enzymic complex that carries out the synthesis of ATP during oxidative phosphorylation are correct except (A) It is located on the matrix side of the inner ... inhibited by oligomycin (C) It can exhibit ATPase activity (D) It can bind molecular O2

Last Answer : D

Description : All the following statements about ketone bodies are true except (A) Their synthesis increases in diabetes mellitus (B) They are synthesized in mitchondria (C) They can deplete the alkali reserve (D) They can be oxidized in the liver

Last Answer : Answer : D

Description : Intermediate in the denovo synthesis of triacyl glycerols include all the following except (A) Fatty acyl CoA (B) CDP diacyl glycerol (C) Glycerol-3-phosphate (D) Lysophosphatidic acid

Last Answer : Answer : B

Description : In synthesis of Triglyceride from α-Glycero phosphate and acetyl CoA, the first intermediate formed is (A) β-diacyl glycerol (B) Acyl carnitine (C) Monoacyl glycerol(D) Phosphatidic acid

Last Answer : Answer : D

Description : Which of the following products of triacylglycerol breakdown and subsequent β-Oxidation may undergo gluconeogenesis? (A) Acetyl CoA (B) Porpionyl CoA (C) All ketone bodies (D) Some amino acids

Last Answer : Answer : B

Description : All the following statements regarding ketone bodies are true except (A) They may result from starvation (B) They are formed in kidneys (C) They include acetoacetic acid and acetone (D) They may be excreted in urine

Last Answer : Answer : B

Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase

Last Answer : Answer : B

Description : In the extra mitochondrial synthesis of fatty acids, CO2 is utilized (A) To keep the system anaerobic and prevent regeneration of acetyl CoA (B) In the conversion of malonyl to CoA hydroxybutyryl CoA (C ... of acetyl CoA to malonyl CoA (D) In the formation of acetyl CoA from 1 carbon intermediates

Last Answer : Answer : C

Description : A hydrocarbon formed in cholesterol synthesis is (A) Mevalonate (B) HMG CoA (C) Squalene (D) Zymosterol

Last Answer : Answer : C

Description : Cholesterol by a feed back mechanism inhibits the activity of (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Thilase (D) Mevalonate kinase

Last Answer : Answer : B

Description : Identify the components labelled A, B, C and D in the diagram below from the list (i) to (viii) given along with Components : (i) Cristae of mitochondria (ii) Inner membrane of mitochondria (iii) Cytoplasm (iv) Smooth endoplasmic ... viii) (vi) (c) (vi) (v) (iv) (vii) (d) (v) (i) (iii) (ii)

Last Answer : (a) (v) (iv) (viii) (iii)

Description : Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?

Last Answer : ATP citrate lyase.

Description : Mitochondrial α-ketoglutarate dehydrogenase complex requires all the following to function except (A) CoA (B) FAD (C) NAD+ (D) NADP+

Last Answer : Answer : D

Description : The following is true of linezolid except: A. It inhibits bacterial protein synthesis at an early step B. It is active against vancomycin resistant enterococci C. It is the drug of choice for enterococcal endocarditis D. It can be administered orally as well as by i.v. infusion

Last Answer : C. It is the drug of choice for enterococcal endocarditis

Description : All of the following tissue are capable of using ketone bodies except (A) Brain (B) Renal cortex (C) R.B.C. (D) Cardiac muscle

Last Answer : Answer : C

Description : Ketone bodies are formed in (A) Kidney (B) Liver (C) Heart (D) Intestines

Last Answer : Answer : B

Description : Ketone bodies are formed in which tissue?

Last Answer : Liver.

Description : In the biosynthesis of triglycerides from glycerol 3-phosphate and acyl-CoA, the first intermediate formed is (A) 2-Monoacylglycerol (B) 1, 2-Diacylglycerol (C) Lysophosphatidic acid (D) Phosphatidic acid

Last Answer : Answer : D

Description : During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103

Last Answer : Answer : A

Description : During each cycle of β-oxidation of fatty acid, all the following compounds are generated except (A) NADH (B) H2O (C) FAD (D) Acyl CoA

Last Answer : Answer : B

Description : Acetyl CoA is not used for the synthesis of (A) Fatty acid (B) Cholesterol (C) Pyruvic acid (D) Citric acid

Last Answer : C

Description : In the biosynthesis of cholesterol, the step which controls the rate and locus of metabolic regulation is (A) Geranyl pyrophosphate farnesyl pyrophosphate (B) Squalene → lanosterol (C) HMG CoA → mevalonate (D) Lanosterol → 1, 4-desmethyl lanosterol

Last Answer : Answer : C

Description : The rage limiting step cholesterol biosynthesis is (A) Squalene synthetase (B) Mevalonate kinase (C) HMG CoA synthetase (D) HMG CoA reductase

Last Answer : Answer : D

Description : The ‘Committed step’ in the biosynthesis of cholesterol from acetyl CoA is (A) Formation of acetoacetyl CoA from acetyl CoA (B) Formation of mevalonate from HMG CoA (C) Formation of HMG CoA from acetyl CoA and acetoacetyl CoA (D) Formation of squalene by squalene synthetase

Last Answer : Answer : B

Description : C22 and C24, fatty acids required for the synthesis of sphingolipids in brain are formed by (A) De novo synthesis (B) Microsomal chain elongation (C) Mitochondrial chain elongation (D) All of these

Last Answer : Answer : B

Description : All of the following statements about puromycin are true except (A) It is an alanyl tRNA analogue (B) It causes premature termination of protein synthesis (C) It inhibits protein synthesis in prokaryotes (D) It inhibits protein synthesis in eukaryotes

Last Answer : Answer : A

Description : Which of the following statements regarding transforming growth factor b (TGF-b) are true? a. TGF-b expression is autoregulated b. TGF-b enhances collagen synthesis c. TGF-b inhibits extracellular matrix production d. TGF-b may inhibit or promote cellular proliferation

Last Answer : Answer: a, b, d TGF-b appears to be one of the key cytokines in control of tissue repair. TGF-b is strongly chemotactic for neutrophils, T cells, monocytes, and fibroblasts. ... TGF-b stimulates the proliferation of densely plated human marrow fibroblasts, but is inhibitory at high concentrations

Description : All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is (a) isocitrate dehydrogenase (b) malate dehydrogenase (c) succinate dehydrogenase (d) lactate dehydrogenase.

Last Answer : (c) succinate dehydrogenase

Description : Ketone bodies are utilized by all tissues except Options: 1) Liver 2) Muscle 3) Heart 4) Kidney

Last Answer : Correct Answer: 1) Liver

Description : Insulin release from pancreatic β cells is augmented by the following except: A. Ketone bodies B. Glucagon C. Vagal stimulation D. Alfa adrenergic agonists

Last Answer : D. Alfa adrenergic agonist

Description : Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by (A) cAMP (B) Prostaglandin (C) Carnitine (D) Choline

Last Answer : Answer : C

Description : Mitochondrial lipogenesis requires (A) bicarbonate (B) biotin (C) acetyl CoA carboxylase (D) NADPH

Last Answer : Answer : D

Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier

Last Answer : Answer : C

Description : The rate limiting step in catecholamine synthesis is catalysed by (A) Phenylalanine hydroxylase (B) Tyrosine hydroxylase (C) Dopa decarboxylase (D) Phenylethanolamine N-methyl transferase

Last Answer : Answer : B

Description : HMG CoA is formed in the metabolism of (A) Cholesterol, ketones and leucine (B) Cholesterol, fatty acid and Leucine (C) Lysine, Lecuine and Isoleucine (D) Ketones, Leucine and Lysine

Last Answer : Answer : A

Description : Each of the following can be an intermediate in the synthesis of phosphatidyl choline except (A) Phosphatidyl inositol (B) CDP-choline (C) Phosphatidyl ethanolamine (D) Diacylglycerol

Last Answer : Answer : A

Description : Which of the following statements about inclusion bodies is incorrect? (a) They are not bound by any membrane. (b) These are involved in ingestion of food particles. (c) They lie free in the cytoplasm. (d) These represent reserve material in cytoplasm.

Last Answer : (b) These are involved in ingestion of food particles

Description : Which one of the following cellular parts is correctly described? (a) Thylakoids - flattened membranous sacs forming the grana of chloroplasts (b) Centrioles - sites for active RNA synthesis (c) Ribosomes - ... cytoplasm are smaller (70S) (d) Lysosomes - optimally active at a pH of about 8.5

Last Answer : (a) Thylakoids - flattened membranous sacs forming the grana of chloroplasts

Description : The chemiosmotic coupling hypothesis of oxidative phosphorylation proposes that adenosine triphosphate (ATP) is formed because (a) a proton gradient forms across the inner membrane (b) there is a ... mitochondrial proteins (d) ADP is pumped out of the matrix into the intermembrane space.

Last Answer : (a) a proton gradient forms across the inner membrane