Description : In synthesis of Triglyceride from α-Glycero phosphate and acetyl CoA, the first intermediate formed is (A) β-diacyl glycerol (B) Acyl carnitine (C) Monoacyl glycerol(D) Phosphatidic acid
Last Answer : Answer : D
Description : In the biosynthesis of triglycerides from glycerol 3-phosphate and acyl-CoA, the first intermediate formed is (A) 2-Monoacylglycerol (B) 1, 2-Diacylglycerol (C) Lysophosphatidic acid (D) Phosphatidic acid
Description : Which one of the following compounds is a key intermediate in the synthesis of both triacyl glycerols and phospholipids? (A) CDP Choline (B) Phosphatidase (C) Triacyl glyceride (D) Phosphatidyl serine
Last Answer : Answer : B
Description : Current concepts concerning the intestinal absorption of triacylglycerols are that (A) They must be completely hydrolysed before the constituent fatty acids can be absorbed (B) They are hydrolysed partially ... portal blood (D) In the absence of bile the hydrolysis of triacyl glycerols is absorbed
Description : Synthesis of polyunsaturated fatty acids involves the enzyme systems: (A) Acyl transferase and hydratase (B) Desaturase and elongase (C) Ketoacyl-CoA reductase and hydratase (D) Dihydroxyacetone phosphate
Last Answer : Answer : A
Description : Adipose tissue which is a store house for triacyl glycerol synthesis the same using (A) The glycerol released by hydrolysis of triacyl glycerol (B) The glycerol-3-phosphate obtained in the metabolism of glucose (C) 2-phosphoglycerate (D) 3-phosphoglycerate
Description : All statements regarding 3-OH-3 methyl glutaryl CoA are true except (A) It is formed in the cytoplasm (B) Required in ketogenesis (C) Involved in synthesis of Fatty acid (D) An intermediate in cholesterol biosynthesis
Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity
Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103
Description : During each cycle of β-oxidation of fatty acid, all the following compounds are generated except (A) NADH (B) H2O (C) FAD (D) Acyl CoA
Description : Each of the following can be an intermediate in the synthesis of phosphatidyl choline except (A) Phosphatidyl inositol (B) CDP-choline (C) Phosphatidyl ethanolamine (D) Diacylglycerol
Description : All of the following subserve as intracellular second messengers in receptor mediated signal transduction except: A. Cyclic AMP B. Inositol trisphosphate C. Diacyl glycerols D. G proteins
Last Answer : D. G proteins
Description : A pathway that requires NADPH as a cofactor is (A) Fatty acid oxidation (B) Extra mitochondrial denovo fatty acid synthesis (C) Ketone bodies formation (D) Glycogenesis
Description : Very low density lipoproteins are relatively rich in (A) Cholesterol (B) Triacyl glycerol (C) Free fatty acids (D) Phospholipids
Description : When the stired triacylglycerol is lipolysed in the adipose tissue blood levels of _____ increased. (A) FFA only (B) Glycerol only (C) Free fatty acids (FFA) and Glycerol (D) Triacyl glycero
Last Answer : Answer : C
Description : Triacyl glycerol synthesis is enhanced by which hormone?
Last Answer : Insulin.
Description : The main pathway for denovo synthesis of fatty acids occur in (A) Cytosol (B) Mitochondria (C) Microsomes (D) Nucleus
Description : This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP: (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thio kinase
Description : Both Acyl carrier protein (ACP) of fatty acid synthetase and coenzyme (CoA) are (A) Contain reactive phosphorylated (B) Contain thymidine (C) Contain phosphopantetheine reactive groups (D) Contain cystine reactive groups
Description : The enzyme acyl-CoA synthase catalyses the conversion of a fatty acid of an active fatty acid in the presence of (A) AMP (B) ADP (C) ATP (D) GTP
Description : Atropine is contraindicated in (a) Cyclic AMP (b) Inositol trisphosphate (c) Diacyl glycerols (d) G protein
Last Answer : Ans: D
Description : Actions of 5-HT2 receptor activation are primarily mediated by: A. Increased membrane permeability to Na+ ions B. Increased formation of cAMP C. Activation of guanylyl cyclase D. Generation of inositol trisphosphate and diacyl glycerols
Last Answer : D. Generation of inositol trisphosphate and diacyl glycerols
Description : Which of the following statements is not true about phospholipids? (a) They are similar to triacylglycerols except that the middle OH group of glycerol reacts with a phosphate rather than with a ... is a phospholipid. (d) The C-2 carbon of glycerol in phosphoacylglycerols has the R configuration
Last Answer : They are similar to triacylglycerols except that the middle OH group of glycerol reacts with a phosphate rather than with a fatty acid
Description : All the following correctly describe the intermediate 3-OH-3-methyl glutaryl CoA except (A) It is generated enzymatically in the mitochondrial matrix (B) It is formed in the cytoplasm (C) It inhibits the first step in cholesterol synthesis (D) It is involved in the synthesis of ketone bodies
Description : Biosynthesis of Triglyceride and Lecithine both require an intermediate: (A) Monoacyl glycerol phosphate (B) Phosphatidic acid (C) Phosphatidyl ethanol amine (D) Phosphatidyl cytidylate
Description : FAD containing enzyme, catalyzing formation of α, β unsaturated fatty acyl CoA derivative. (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thiolase
Description : Conversion of fatty acyl-CoA to an acylCoA derivative having 2 more carbon atoms involves as acetyl donar: (A) Acetyl-CoA (B) Succinyl-CoA (C) Propionyl-CoA (D) Malonyl-CoA
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by (A) cAMP (B) Prostaglandin (C) Carnitine (D) Choline
Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Description : Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+
Description : Long chain fatty acids are first activated to acyl CoA in the (A) Cytosol (B) Mitochodria (C) Ribosomes (D) Microsome
Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier
Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form
Description : Acetyl CoA formed from pyruvate can be used for the synthesis of all the following except (A) Glucose (B) Fatty acids (C) Cholesterol (D) Steroid hormones
Description : Acyl carrier protein is involved in the synthesis of (A) protein (B) glycogen (C) fatty acid outside the mitochondria (D) fatty acid in the mitochondria
Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase
Description : Protein kinase C is activated by (A) Cyclic AMP (B) Cyclic GMP (C) Diacyl glycerol (D) Inositol triphosphate
Description : Glycerol-3-phosphate for the synthesis of triglycerides in adipose tissue is derived from (A) Phosphatidic acid (B) Diacylglycerol (C) Glycerol (D) Glucose
Description : Which of the following regulates lipolysis in adipocytes? (A) Activation of fatty acid synthesis mediated by CAMP (B) Glycerol phosphorylation to prevent futile esterification of fatty acids (C) ... result of hormone stimulated increases in CAMP levels (D) Activation of CAMP production by Insulin
Description : The triacyl glycerol present in plasma lipoproteins are hydrolyzed by (A) Linqual lipase (B) Pancreatic lipase (C) Colipase (D) Lipoprotein lipase
Description : Depot fats of mammalian cells comprise mostly of (A) Cholesterol (B) Cholesterol esters (C) Triacyl glycerol (D) Phospholipids
Description : Complete digestion of triacyl glycerol (triglyceride) in gastro intestinal tract needs what enzymes?
Last Answer : Pancreatic lipase, co-lipase, isomerase and bile salts
Description : Which one of the following compounds cannot give rise to the net synthesis of Glucose? (A) Lactate (B) Glycerol (C) α-ketoglutarate (D) Acetyl CoA
Last Answer : B
Description : The major determinant of the overall rate of denovo purine nucleotide biosynthesis is the concentration of (A) 5-phosphoribosyl 1-pyrophosphate (B) 5-phospho β-D-ribosylamine (C) Glycinamide ribosyl-5-phosphate (D) Formylglycinamide ribosyl-5-phosphate
Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP
Description : Which of the following cofactors or their derivatives must be present for the conversion of acetyl CoA to malonyl CoA extramitochondrial fatty acid synthesis? (A) Biotin (B) FAD (C) FMN (D) ACP