Mitochondrial α-ketoglutarate dehydrogenase complex requires all the following to function except (A) CoA (B) FAD (C) NAD+ (D) NADP+

1 Answer

Answer :

Answer : D

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Description : The reaction catalysed by α-ketoglutarate dehydrogenase in the citric acid cycle requires (A) NAD (B) NADP (C) ADP (D) ATP

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Description : Pyruvate dehydrogenase complex and α-ketoglutarate dehydrogenase complex require the following for their oxidative decarboxylation: (A) COASH and Lipoic acid (B) NAD+ and FAD (C) COASH and TPP (D) COASH, TPP,NAD+,FAD, Lipoate

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Description : β-Oxidation of fatty acids requires all the following coenzymes except (A) CoA (B) FAD (C) NAD (D) NADP

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Description : In β-oxidation, the coenzyme for acyl-CoA dehydrogenase is (A) FMN (B) NAD (C) NADP (D) FAD

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Description : UDP glucose is converted to UDP glucurronate, a reaction catalysed by UDP glucose dehydrogenase requires (A) NAD+ (B) FAD (C) NADP (D) FMN

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Description : For reduction enzyme HMG-CoA reductase requires cofactor: (A) NADPH (B) NADP (C) NAD (D) FAD

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Description : Decarboxylation of α-keto acids requires (A) Thiamine pyrophosphate, FAD, NAD+ (B) Flavin mononucleotide (C) NADP+ (D) NAD+ only

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Description : Pyruvate dehydrogenase contains all except (A) Biotin (B) NAD (C) FAD (D) CoA

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Description : A cofactor in the conversion of dihydroorotate to orotic acid, catalysed by the enzyme dihydroorotate dehydrogenase is (A) FAD (B) FMN (C) NAD (D) NADP

Last Answer : Answer : C

Description : Isocitrate dehydrogenase can use __________ as a cofactor. (A) NAD+ only (B) NADP+ only (C) NAD+ or NADP+ (D) FMN and FAD

Last Answer : Answer : C

Description : Retinol and retinal are interconverted requiring dehydrogenase or reductase in the presence of (A) NAD or NADP (B) NADH + H+ (C) NADPH (D) FAD

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Description : Dehydrogenase enzymes of the hexose monophosphate shunt are (A) NAD+ specific (B) NADP+ specific (C) FAD specific (D) FMN specific

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Description : UDPG is oxidized to UDP glucuronic acid by UDP dehydrogenase in presence of (A) FAD+ (B) NAD+ (C) NADP+ (D) ADP+

Last Answer : B

Description : Group transferring Co-enzyme is (A) CoA (B) NAD+ (C) NADP+ (D) FAD+

Last Answer : Answer : A

Description : The coenzyme involved in dehydrogenation of 3-hydroxy acyl-CoA is (A) FAD (B) FMN (C) NAD (D) NADP

Last Answer : Answer : C

Description : An examp le of group transferr ing coenzyme is (A) NAD+ (B) NADP+ (C) FAD (D) CoA

Last Answer : Answer : D

Description : Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+

Last Answer : Answer : C

Description : Carboxylation of acetyl—CoA to malonyl — CoA takes place in presence of (A) FAD+ (B) Biotin (C) NAD+ (D) NADP+

Last Answer : Answer : C

Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase

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Description : DNA ligase of E. coli requires which of the following co-factors? (A) FAD (B) NAD+ (C) NADP+ (D) NADH

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Description : In Krebs’ cycle, the FAD precipitates as electron acceptor during the conversion of (a) fumaric acid to malic acid (b) succinic acid to fumaric acid (c) succinyl CoA to succinic acid (d) α-ketoglutarate to succinyl CoA.

Last Answer : (b) succinic acid to fumaric acid

Description : Dehydrogenases utilize, as coenzymes, all of the following except (A) NAD+ (B) NADP+ (C) FAD (D) FH4

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Description : FAD containing enzyme, catalyzing formation of α, β unsaturated fatty acyl CoA derivative. (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thiolase

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Description : In the biosynthesis of heme, condensation between succinyl CoA and glycine requires (A) NAD+ (B) FAD (C) NADH + H+ (D) B6-phosphate

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Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase

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Description : All the isoenzymes function with the coenzyme: (A) NADP+ (B) FAD (C) Lipoate (D) NAD+

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Description : The prosthetic group of aerobic dehydrogenases is (A) NAD (B) NADP (C) FAD (D) Pantothenic acid

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Description : The hydrogen acceptor used in pentose phosphate pathway is (A) NAD (B) NADP (C) FAD (D) FMN

Last Answer : Answer : B

Description : In β−oxidation of fatty acids which of the following are utilized as co-enzymes? (A) NAD+ and NADP+ (B) FAD H2 and NADH + H+ (C) FAD and FMN (D) FAD and NAD+

Last Answer : Answer : D

Description : In β-Oxidation of fatty acids, which of the following are utilized as coenzymes? (A) NAD+ and NADP+ (B) FADH2 and NADH + H+ (C) FAD and FMN (D) FAD and NAD+

Last Answer : Answer : D

Description : Dehydrogenases involved in HMP shunt are specific for (A) NADP+ (B) NAD+ (C) FAD (D) FMN

Last Answer : A

Description : Reducing equivalents from succinate enter the mitochondrial respiratory chain at (A) NAD (B) Coenzyme Q (C) FAD (D) Cyt c

Last Answer : Answer : C

Description : Pantothenic acid acts on (A) NADP (B) NADPH (C) FAD (D) CoA

Last Answer : Answer : B

Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these

Last Answer : Answer : D

Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP

Last Answer : Answer : A

Description : Isocitrate dehydrogenase is allosterically inhibited by (A) Oxalosuccinate (B) α-Ketoglutarate (C) ATP (D) NADH

Last Answer : Answer : C

Description : Malonate is an inhibitor of (A) Malate dehydrogenase (B) α-Ketoglutarate dehydrogenase (C) Succinate dehydrogenase (D) Isocitrate dehydrogenase

Last Answer : Answer : C

Description : The hexose monophosphate pathway includes the enzyme: (A) Maltase dehydrogenase (B) Hexokinase (C) α-Ketoglutarate dehydrogenase (D) Glucose-6-phosphate dehydrogenase

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Description : In TCA cycle, oxalosuccinate is converted to α-ketoglutarate by the enzyme: (A) Fumarase (B) Isocitrate dehydrogenase (C) Aconitase (D) Succinase

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Description : An enzyme of the citric acid cycle also found outside the mitochondria is (A) Isocitrate dehydrogenase (B) Citrate synthetase (C) α-Ketoglutarate dehydrogenase (D) Malate dehydrogenase

Last Answer : Answer : C

Description : Lipoic acid is a conenzyme for (A) Pyruvate dehydrogenase (B) α-Ketoglutarate dehydrogenae (C) Both (A) and (B) (D) None of these

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Description : Formation of succinyl-CoA from α-Ketoglutarate is inhibited by (A) Fluoroacetate (B) Arsenite (C) Fluoride (D) Iodoacetate

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Description : The example of generation of a high energy phosphate at the substrate level in the citric acid cycle is the reaction: (A) Isocitrate α-Ketoglutarate (B) Succinate α-fumarate (C) Malate α-oxaloacetate (D) Succinyl CoA α-Succinate

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Description : Which one of the following compounds cannot give rise to the net synthesis of Glucose? (A) Lactate (B) Glycerol (C) α-ketoglutarate (D) Acetyl CoA

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Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate

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Description : Magnesium ions are required in the reactions involving (A) NAD (B) FAD (C) ATP (D) CoA

Last Answer : Answer : C

Description : The coenzyme not involved in the formation of acetyl-CoA from pyruvate is (A) TPP (B) Biotin (C) NAD (D) FAD

Last Answer : Answer : B

Description : The cofactor or its derivative required for the conversion of acetyl CoA to malonylCoA is (A) FAD (B) ACP (C) NAD+ (D) Biotin

Last Answer : Answer : D

Description : The enzyme -ketoglutarate dehydrogenase in the citric acid cycle requires (A) Lipoate (B) Folate (C) Pyridoxine (D) Inositol

Last Answer : Answer : A