Description : Ventricular remodeling after myocardial infarction involves the mediation of: A. Angiotensin II B. Prostaglandin C. Bradykinin D. Thromboxane A2
Last Answer : A. Angiotensin II
Description : The following are true about chemicals involved in allergic reaction: a. thromboxane -leukocyte activation b. prostaglandin-2 - vasodilatation c. platelet-activating factor - leukocyte activation d. heparin - augments inactivation of prostaglandins
Last Answer : prostaglandin-2 - vasodilatation
Description : Aldosterone enhances Na+ reabsorption in renal tubules by: A. Stimulating carbonic anhydrase B. Activating Na+ K+ ATPase C. Inducing the synthesis of Na+ K+ ATPase D. Inducing renal prostaglandin synthesis
Last Answer : C. Inducing the synthesis of Na+ K+ ATPase
Description : Prolonged airway hyperreactivity is characteristically caused by: A. Histamine B. Prostaglandin E2 C. Platelet activating factor D. Bradykinin
Last Answer : C. Platelet activating factor
Description : Dysmenorrhoea is often associated with excess production of the following autacoid by the endometrium: A. Bradykinin B. Prostaglandin C. Platelet activating factor D. 5-Hydroxytryptamine
Last Answer : B. Prostaglandin
Description : Select the receptor that is located intracellularly: A. Opioid μ receptor B. Steroid receptor C. Prostaglandin receptor D. Angiotensin receptor
Last Answer : B. Steroid receptor
Description : Hepatic glycogenoloysis is increased by (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids ENZYMES 163
Last Answer : Answer : B
Description : HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids
Last Answer : Answer : A
Description : Secretion of mineralcorticoids is increased by (A) ACTH (B) Angiotensin (C) Hypokalaemia (D) Hypernatraemia
Description : Following acute haemorrhage, the following compensatory mechanisms occur: a. increased chemoreceptor discharge b. increased level of circulating angiotensin II c. vasoconstriction of renal efferent arterioles d. all above
Last Answer : all above
Description : Select the drug which is active against a variety of diarrhoea producing organisms like Giardia, Shigella, Salmonella as well as S. typhi and Trichomonas vaginalis, but is not a first line treatment for any of these: A. Metronidazole B. Mepacrine C. Cotrimoxazole D. Furazolidone
Last Answer : D. Furazolidone
Description : The following drug is a causal prophylactic for falciparum malaria and suppressive prophylactic for vivax malaria: A. Chloroquine B. Mepacrine C. Quinine D. Proguanil
Last Answer : D. Proguanil
Description : Vasoconstrictor effect of ADH is mediated by (A) cAMP (B) cGMP (C) Protein kinase C (D) Angiotensin II
Last Answer : Answer : C
Description : Aldosterone release is stimulated by (A) α2-Globulin (B) Renin (C) Angiotensin II (D) Growth hormone
Description : In the rennin-angiotensin system the primary hormone is (A) Angiotensinogen (B) Angiotensin I (C) Angiotensin II (D) Angiotensin III
Description : Which of the following statements regarding cytokines is incorrect? A. Cytokines act directly on target cells and may potentiate the actions of one another. B. Interleukin 1 (IL-1) ... organ dysfunction syndrome because of its multiple actions and the secondary cascades that it stimulates.
Last Answer : Answer: C DISCUSSION: Cytokines are soluble peptide molecules that are synthesized and secreted by a number of cell types in response to injury, inflammation, and infection. Cytokines, which ... is thought to play a central role in the stress response, particularly in response to endotoxemia
Description : The actions of platelet activating factor include the following except: A. Increased capillary permeability B. Bronchodilatation C. Vasodilatation D. Erosion of gastric mucosa
Last Answer : B. Bronchodilatation
Description : The symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cell (e) Decreased prostaglandin production
Last Answer : Ans: A
Description : The Symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cells (e) Decreased prostaglandin production
Description : Cervical priming with prostaglandin results in (a) Facilitation of sperm movement through cervical canal (b) Increased cervical tone (c) Softening of cervix (d) Increased cervical secretions
Last Answer : Ans: C
Description : A patient who has been taking quantities of aspirin might show increased post operative bleeding because aspirin inhibits:** A. Synthesis of thromboxane A2 and prevents platelet aggregation B. ... network E. Increase the absorption of vitamin K and prevents synthesis of blood clotting factors
Last Answer : A. Synthesis of thromboxane A2 and prevents platelet aggregation
Description : Cervical priming with prostaglandin results in: A. Facilitation of sperm movement through cervical canal B. Increased cervical tone C. Softening of cervix D. Increased cervical secretions
Last Answer : C. Softening of cervix
Description : Which of the following statement(s) is/are true concerning the neuroendocrine responses to shock? a. Sympathetic nerve endings release epinephrine which is responsible for greater than 80% ... injury and sepsis d. The renin-angiotensin axis further augments the sympathetic-mediated vasoconstriction
Last Answer : Answer: c, d The neuroendocrine response to shock attempts to achieve restoration of effective blood volume, mobilization of metabolic substrates, and maintenance of central ... . Angiotensin II is an extremely effective vasoconstrictor that further augments sympathetic-mediated vasoconstriction
Description : Fight-or-flight reactions cause activation of (a) the parathyroid glands, leading to increased metabolic rate (b) the kidney, leading to suppression of renin- angiotensin-aldosterone pathway (c) ... epinephrine and norepinephrine (d) the pancreas leading to a reduction in the blood sugar levels.
Last Answer : (c) the adrenal medulla, leading to increased secretion of epinephrine and norepinephrine
Description : Lack of Glucocorticoids and mineral corticoids might be consequence of which of the following defects in the adrenal cortex? (A) Androstenadione deficiency (B) Estrone deficiency (C) 17 α-OH progesterone deficiency (D) C- α-Hydroxylase deficiency
Last Answer : Answer : D
Description : It is unique that the following single antidiabetogenic hormone effectively counter acts the several diabetogenic hormones: (A) Glucagon (B) Glucocorticoids (C) Insulin (D) Growth hormone
Description : In adrenogenital syndrome due to total absence of 21-hydroxylase in adrenal cortex, there is (A) Deficient secretion of glucocorticoids (B) Deficient secretion of mineralcorticoids (C) Excessive secretion of androgens (D) All of these
Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt
Description : Secretion of glucocorticoida is regulated by all the following except (A) Hypothalamus (B) Anterior pituitary (C) Feedback control by blood glucose (D) Feedback control by glucocorticoids
Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase
Description : Glucocorticoids increase all of the following except (A) Gluconeogenesis (B) Lipolysis in extremities (C) Synthesis of elcosanoida (D) Hepatic glycogenesis
Description : The second messenger for glucocorticoids is (A) Cyclic AMP (B) Cyclic GMP (C) Inositol triphosphate (D) No second messenger is required
Description : All the following statements about transcortin are true except (A) It is synthesised in liver (B) It transports glucocorticoids (C) It transports aldosterone (D) It transports progesterone
Description : Glucocorticoids are transported in blood (A) In association with transcortin chiefly (B) In association with albumin to some extent (C) In free form partly (D) All of these
Description : Zona glomerulosa of adrenal cortex synthesises (A) Glucocorticoids (B) Mineralocorticoids (C) Androgens (D) Estrogen and progesterone HORMONE METABOLISM 223
Description : The defect in adrenal cortex responsible for lack of glucocorticoids and mineralcorticoids is (A) Androstenedione deficiency (B) 17 α -OH progesterone deficiency (C) C-21 hydroxylase deficiency (D) Testosterone deficiency HORMONE METABOLISM 209
Description : Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6-biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase (D) Stimulation of synthesis of eltroxykinase
Description : ACTH stimulates the secretion of (A) Glucocorticoids (B) Epinephrine (C) Thyroxine (D) Luteinizing hormone
Description : Synthesis of prostaglandins is inhibited by (A) Glucocorticoids (B) Aspirin (C) Indomethacin (D) All of these
Description : Gluconeogenesis is decreased by (A) Glucagon (B) Epinephrine (C) Glucocorticoids (D) Insulin
Last Answer : D
Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity
Description : Some hormones produce their intracellular effects by activating (A) Phospholipae A1 (B) Phospholipase B (C) Phospholipase C (D) All of these
Description : If a coenzyme is required in an enzyme reaction, the former usually has the function of (A) Acting as an acceptor for one of the cleavage products of the substrate (B) Enhancing the specificity ... C) Increasing the number of receptor sites of the apo enzyme (D) Activating the substrate ENZYMES 167
Description : The hormone activating the glycogen synthase activity is (A) Insulin (B) Glucagon (C) Epinephrine (D) ACTH
Description : Dipalmitoyl lecithin acts as (A) Platelet activating factor (B) Second messenger for hormones (C) Lung surfactant (D) Anti-ketogenic compound
Description : Vinca alkaloids exert antitumor activity by: A. Activating topoisomerase II to cause breaks in DNA strands B. Crosslinking DNA strands C. Inhibiting DNA mediated RNA synthesis D. Inhibiting polymerization of tubulin to form intracellular microtubules
Last Answer : D. Inhibiting polymerization of tubulin to form intracellular microtubules
Description : Hormonal stimulation of the formation of the second messenger inositol 1,4,5 triphosphate (IP3) quickly leads to the release of which other intracellular messenger? (A) cAMP (B) Prostaglandin (C) Calcinon (D) Leukotriene
Description : Adenylate cyclase is activated by (A) Insulin (B) Glucagon (C) Prostaglandin E1 (D) Ca2+ ions
Description : Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by (A) cAMP (B) Prostaglandin (C) Carnitine (D) Choline