Description : Microsomes are small spherical membranous vesicles with attached ribosomes. They sediment, during differential sedimentation, only in the late stages of a preparation when very high centrifugal velocities are used. They don’t appear in electronmicrographs of a cell. From where do they arise?
Last Answer : Fragments of endoplasmic reticulum are transformed from lipid bilayer sheets, with attached ribosomes, into spherical vesicles. This is a result of the homogenization used in preparing the samples and also the tendency of lipid bilayers to spontaneously reseal.