Prothrombin time is prolonged by administering (A) Vitamin K (B) Dicoumarol (C) Calcium (D) Prothrombin

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Answer :

Answer : A

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Description : Prothrombin time is prolonged by administering (A) Vitamin K (B) Dicoumarol (C) Calcium (D) Prothrombin

Last Answer : Answer : B

Description : Prothrombin time is prolonged in (A) Vitamin K deficiency (B) Liver damage (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Last Answer : Answer : B

Description : Prothrombin time remains prolonged even after parenterals administration of vitamin K in (A) Haemolytic jaundice (B) Liver damage (C) Biliary obstruction (D) Steatorrhoea

Last Answer : Answer : B

Description : A patient on dicoumarol treatment needs extraction. Which of the following is MOST valuable in evaluating surgical risks: A. Clotting time B. Bleeding time C. Prothrombin time D. Sedimentation rate E. Complete blood cell count

Last Answer : C. Prothrombin time

Description : The anti-vitamin for para amino benzoic acid is (A) Aminopterin (B) Dicoumarol (C) INH (D) Sulphanomides

Last Answer : Answer : D

Description : An anti-vitamin for folic acid is (A) Aminopterin (B) Dicoumarol (C) Pyrithiamine (D) Isoniazid

Last Answer : Answer : A

Description : The anti-vitamin for para amino benzoic acid is (A) Aminopterrin (B) Dicoumarol (C) INH (D) Sulphonamides

Last Answer : Answer : D

Description : An anti-vitamin for folic acid is (A) Amethoptesin (B) Dicoumarol (C) Pyrithoamine (D) Isoniazid

Last Answer : Answer : A

Description : The anti vitamin for para aminobenzoic acid is (A) Aminopterin (B) Dicoumarol (C) Sulphonamides (D) Thiopanic acid

Last Answer : Answer : C

Description : All the following conditions produce a real or functional deficiency of vitamin K except (A) Prolonged oral, broad spectrum antibiotic therapy (B) Total lack of red meat in the diet (C) The total lack of green leafy vegetables in the diet (D) Being a new born infant

Last Answer : Answer : B

Description : Von Willebrand's disease is a common, congenital bleeding disorder. Which of the following statement(s) is/are true concerning Von Willebrand's disease? a. As in hemophilia, it is ... -treatment for elective surgery require administration of cryoprecipitate to achieve levels of 23-50% of normal

Last Answer : Answer: c, d Von Willebrand's factor is an adhesive protein that mediates platelet adhesion to collagen. In addition, it protects and prevents the rapid removal of factor VIII ... platelet aggregation responses to ristocetin. The most reliable source of Von Willebrand's factor is cryoprecipitate

Description : Which of the following statement(s) concerning laboratory studies used in monitoring a patient with intravenous heparinization is/are correct? a. The platelet count should be followed because of the ... serum creatinine should be measured daily to allow adjustments in dose based on renal function

Last Answer : Answer: a, c In monitoring the effect of heparin, an activated partial thromboplastin time (aPTT) of 1.5 control or a thrombin clotting time (TCT) of 2 times control reflects adequate ... system. Therefore the dose of heparin need not be adjusted in cases of liver or renal dysfunction

Description : The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. all above

Last Answer : all above

Description : The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. is increased by heparin

Last Answer : assess the extrinsic pathway of the blood coagulation cascade

Description : The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration ... warfarin be continued for at least one year after initial episode of deep venous thrombosis

Last Answer : Answer: a, b Warfarin interferes with the vitamin K dependent clotting factors II, VII, IX and X, protein C, and protein S. An important complication of warfarin is skin ... the benefit from anticoagulant therapy and thus is the basis for discontinuing warfarin administration at this time

Description : The transfusion of fresh frozen plasma (FFP) is indicated for which of the following reasons? A. Volume replacement. B. As a nutritional supplement. C. Specific coagulation factor deficiency ... the correction of abnormal PT secondary to warfarin therapy, vitamin K deficiency, or liver disease.

Last Answer : Answer: CD DISCUSSION: The use of FFP as a volume expander is not indicated. There are currently several preparations (both crystalloid and colloid) that are equally effective and do not carry the infectious and ... vitamin K-dependent factors II, VII, IX, and X, as well as protein C and protein S

Description : Which of the following is not true about warfarin, a. INR of 3 is enough to start any extraction. b. Affects extrinsic system and increases prothrombin time. c. Heparin can be given subcutaneously ... rapidly. d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Last Answer : d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Description : Which of the following is not true about warfarin, ** A. INR of 3 is enough to start any extraction B. Affects extrinsic system and decreases prothrombin time C. Heparin can be given subcutaneously and acts rapidly D. It takes up to 12 hours for Vitamin K to reverse the effects of warfarin

Last Answer : B. Affects extrinsic system and decreases prothrombin time

Description : The specific role of Vitamin K is in the synthesis of - (1) Albumin. (2) Antibodies (3) Globulin (4) Prothrombin

Last Answer : (4) Prothrombin Explanation: Vitamin K is a necessary participant in synthesis of several proteins that mediate both coagulation and anticoagulation. It is noteworthy for the synthesis of Prothrombin ( ... in the clotting process. Vitamin K is integrally involved in the clotting mechanism of blood.

Description : Vitamin K is required for (a) change of prothrombin into thrombin (b) synthesis of prothrombin (c) change of fibrinogen to fibrin (d) formation of thromboplastin.

Last Answer : (b) synthesis of prothrombin

Description : The specific role of Vitamin K is in the synthesis of (1) Albumin (2) Antibodies (3) Globulin (4) Prothrombin

Last Answer : Prothrombin

Description : In parenhymatous liver disease the prothrombin time (A) Remains normal (B) Increases (C) Decreases (D) Responds to Vit K

Last Answer : Answer : B

Description : In obstructive jaundice prothrombin time (A) Remains normal (B) Decreases (C) Responds to vit K and becomes normal (D) Responds to vit K and increases

Last Answer : Answer : C

Description : An early effect of vitamin a deficiency is (A) Xerophthalmia (B) Keratomalacia (C) Prolonged dark adaptation time (D) Follicular hyperkeratosis

Last Answer : Answer : C

Description : Dicoumarol is antagonist to (A) Riboflavin (B) Retinol (C) Menadione (D) Tocopherol

Last Answer : Answer : C

Description : Hypervitaminosis K in neonates may cause (A) Porphyria (B) Jaundice (C) Pellagra (D) Prolonged bleeding

Last Answer : Answer : B

Description : Calcium absorption is increased by (A) Vitamin D (B) Vitamin C (C) Vitamin K (D) Vitamin E

Last Answer : Answer : A

Description : Which vitamin is required for formation of Prothrombin?

Last Answer : Vitamin K

Description : What is dicoumarol? How does this substance act in the clotting process and what are some examples of its toxicity?

Last Answer : Dicoumarol is an anticoagulant drug. Due to its molecular structure dicoumarol competes with vitamin K for the binding to substrates blocking the formation of clotting factors and interrupting ... administered during pregnancy since they pass the placental barrier and can cause fetal hemorrhages.

Description : What is true of nicotinic acid as well as nicotinamide: A. Both possess vitamin B3 activity B. Both cause cutaneous vasodilatation C. Both lower plasma triglyceride and VLDL levels D. Both cause hyperglycaemia after prolonged medication

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Description : A test to evaluate detoxifying function of liver is (A) Serum albumin: globulin ratio (B) Galactose tolerance test (C) Hippuric acid test (D) Prothrombin time

Last Answer : Answer : C

Description : The normal levels of prothrombin time is about (A) 2 sec (B) 4 sec (C) 14 sec (D) 10–16 sec

Last Answer : Answer : C

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Description : Prothrombin is synthesised in (A) Erythrocytes (B) Reticulo-endothelial cells (C) Liver (D) Kidneys

Last Answer : Answer : C

Description : Prolonged and severe iron deficiency can cause astrophy of epithelium of (A) Oral cavity (B) Oesophagus (C) Stomach (D) All of these

Last Answer : Answer : D

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Last Answer : Answer : A

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