Description : Conversion of glucose to glucose-6- phosphate in human liver is by (A) Hexokinase only (B) Glucokinase only (C) Hexokinase and glucokinase (D) Glucose-6-phosphate dehydrogenase
Last Answer : C
Description : Glucose-6-phosphate is an allosteric inhibitor of (A) Glucokinase (B) Hexokinase (C) Phosphohexose isomerase (D) None of these
Last Answer : Answer : B
Description : During fasting, glucose is phosphorylated mainly by (A) Hexokinase (B) Glucokinase (C) Both (A) and (B) (D) None of these
Last Answer : Answer : A
Description : The enzymes involved in Phosphorylation of glucose to glucose 6- phosphate are (A) Hexokinase (B) Glucokinase (C) Phosphofructokinase (D) Both (A) and (B)
Last Answer : D
Description : Hexokinase has a high affinity for glucose than (A) Fructokinase (B) Galactokinase (C) Glucokinase (D) All of the above
Description : Insulin decreases the synthesis of (A) Hexokinase (B) Glucokinase (C) PEP carboxykinase (D) Glycogen synthetase
Last Answer : Answer : C
Description : ATP is a co-substrate as well as an allosteric inhibitor of (A) Phosphofructokinase (B) Hexokinase (C) Glucokinase (D) None of these
Description : Glucokinase (A) Is widely distributed and occurs in most mammalian tissues (B) Has a high km for glucose and hence is important in the phosphorylation of glucose primarily after ingestion of a carbohydrate rich meal (C) Is widely distributed in Prokaryotes (D) None of these
Last Answer : B
Description : Glucokinase is found in (A) Muscles (B) Brain (C) Liver (D) All of these
Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase
Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Description : he dominant pharmacokinetic feature of penicillin G is: A. It is equally distributed extra- and intracellularly B. It is rapidly secreted by proximal renal tubules C. It has low oral bioavailability ... pass metabolism in liver D. It does not cross blood-CSF barrier even when meninges are inflamed
Last Answer : B. It is rapidly secreted by proximal renal tubules
Description : The blood - brain barrier: a. is permeable to bilirubin at birth b. is formed by the tight junctions between endothlial cells and the end feet processes of astrocytes c. is permeable to glucose d. all above
Last Answer : all above
Description : In the normal resting state of human most of the blood glucose burnt as fuel is consumed by (A) Liver (B) Brain (C) Adipose tissue (D) Muscles
Description : In the normal resting state of humans, most of the blood glucose burned as fuel is consumed by (A) Liver (B) Adipose tissue (C) Muscle (D) Brain
Description : The normal resting state of humans, most of the blood glucose burnt as “fuel” is consumed by (A) Liver (B) Brain (C) Kidneys (D) Adipose tissue
Description : Hexokinase (Glucose + ATP → Glucose-6– P + ADP) belongs to the category: (A) Transferases (B) Lysases (C) Oxidoreductases (D) Isomerases
Description : The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase
Description : The hexose monophosphate pathway includes the enzyme: (A) Maltase dehydrogenase (B) Hexokinase (C) α-Ketoglutarate dehydrogenase (D) Glucose-6-phosphate dehydrogenase
Last Answer : Answer : D
Description : Hexokinase is inhibited in an allosteric manner by (A) Glucose-6-Phosphate (B) Glucose-1-Phosphate (C) Fructose-6-phosphate (D) Fructose-1, 6-biphosphate
Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency
Description : Which of the following is not an enzyme involved in glycolysis? (A) Euolase (B) Aldolose (C) Hexokinase (D) Glucose oxidase
Description : The need to produce concentrated urine is detected in the brain is due to the increase in the concentration of (a) Glucose in the blood (b) K+ in the blood (c) Na+ in the blood (d) Carbonic acid in the blood
Last Answer : Ans:(c)
Description : Hyper insulinism can cause coma since (A) The chief nutrient for the brain is glucose (B) The chief nutrient for the heart is glucose (C) The glucostatic role of the liver is damaged (D) The kidneys are damaged
Description : Glucose-1-phosphate liberated from glycogen cannot be converted into free glucose in (A) Liver (B) Kidneys (C) Muscles (D) Brain
Description : The enzyme glucose 6-phosphatase is present in (A) Liver (B) Muscle (C) Adipose tissue (D) Brain
Description : The hydrolysis of Glucose-6-phosphate is catalysed by a specific phosphatase which is found only in (A) Liver, intestines and kidneys (B) Brain, spleen and adrenals (C) Striated muscle (D) Plasma
Last Answer : A
Description : Blood brain barrier can be crossed by (A) Epinephrine (B) Dopamine (C) Dopa (D) All of these
Description : A hormone which cannot cross the blood brain barrier is (A) Epinephrine (B) Aldosterone (C) ACTH (D) TSH
Description : 06. A hydrophilic medicinal agent has the following property: a) Low ability to penetrate through the cell membrane lipids b) Penetrate through membranes by means of endocytosis c) Easy permeation through the blood-brain barrier d) High reabsorption in renal tubules
Last Answer : a) Low ability to penetrate through the cell membrane lipids
Description : An example of competitive inhibition of an enzyme is the inhibition of a. Succinic dehydrogenase by malonic acid b. Cytochrome oxidase by cyanide c. Hexokinase by glucose-6-phosphate d. Carbonic anhydrase by carbon dioxide
Last Answer : Ans: A
Description : Conversion of glucose to glucose-6-phosphate, the first irreversible reaction of glycolysis, is catalysed by (a) phosphofructokinase (b) aldolase (c) hexokinase (d) enolase.
Last Answer : (c) hexokinase
Description : A specific fructokinase present in liver has a very high affinity for its substrate because (A) Km for fructose is very high (B) Km for fructose is very low (C) Activity is affected by fasting (D) Activity is affected by insulin
Description : A gluconeogenic enzyme among the following is (A) Phosphofructokinase (B) Pyruvate kinase (C) Phosphoenol pyruvate carboxykinase (D) Glucokinase
Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency
Description : Synthesis of the following enzymes is increased during starvation. (A) Digestive enzymes (B) Gluconeogenic enzymes (C) Urea cycle enzymes (D) Glucokinase
Description : What is glucokinase?
Last Answer : The reaction is similar to hexokinase. But glucokinase is present only in liver, acts specifically on glucose, and is active when glucose level in blood is increased after a food.
Description : McArdle’s disease is due to the deficiency of (A) Glucose-6-phosphatase (B) Phosphofructokinase (C) Liver phosphorylase (D) muscle phosphorylase
Description : Which one of the following tissues can metabolize glucose, fatty acids and ketone bodies for ATP production? a. Liver b. Muscle c. Brain d. R.B.C
Last Answer : Ans: B
Description : Glucose entry into the cells of the following organ/ tissue is highly dependent on the presence of insulin: A. Brain B. Liver C. Adipose tissue D. Kidney tubules
Last Answer : C. Adipose tissue
Description : Blood glucose level can be raised by gluconeogenesis only by liver, why?
Last Answer : Glucose-6-phosphatase is present only in liver.
Description : Hormone receptors possess all the following properties except (A) All of them are proteins (B) They possess a recognition domain (C) They bind hormones with a high degree of specificity (D) Number of receptors in a target cell is constant
Description : Thyroid stimulating hormone is a dimer. The α-subunits of TSH, LH, FSH are identical. Thus the biological specificity must therefore be β subunit in which the number of amino acids is (A) 78 (B) 112 (C) 130 (D) 199
Description : An allosteric enzyme influences the enzyme activity by (A) Competiting for the catalytic site with the substrate (B) Changing the specificity of the enzyme for the substrate (C) Changing the conformation ... binding to a site other than catalytic site (D) Changing the nature of the products formed
Description : If a coenzyme is required in an enzyme reaction, the former usually has the function of (A) Acting as an acceptor for one of the cleavage products of the substrate (B) Enhancing the specificity ... C) Increasing the number of receptor sites of the apo enzyme (D) Activating the substrate ENZYMES 167
Description : Example of enzyme specificity: (A) Stereo specificity (B) Reaction specificity (C) Substrate specificity(D) All of these
Description : Give an example for group specificity.
Last Answer : trypsin can hydrolyse peptide bonds formed by carboxyl groups of arginine or lysine residues.
Description : Give an example for absolute specificity.
Last Answer : Urea is the only substrate for urease.
Description : What are the types of specificity shown by enzymes?
Last Answer : Absolute specificity, group specificity and streospecificity.