Description : Two examples of substrate level phosphorylation in EM pathway of glucose metabolism are in the reactions of (A) 1,3 bisphosphoglycerate and phosphoenol pyruvate (B) Glucose-6 phosphate ... phosphate (C) 3 phosphoglyceraldehyde and phosphoenolpyruvate (D) 1,3 diphosphoglycerate and 2-phosphoglycerate
Last Answer : A
Description : Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate
Last Answer : C
Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte
Description : Erythrocytes under normal conditions and microorganisms under anaerobic conditions may accumulate (A) NADPH (B) Pyruvate (C) Phosphoenolpyruvate (D) Lactate
Last Answer : Answer : D
Description : Pyruvate dehydrogenase a multienzyme complex is required for the production of (A) Acetyl-CoA (B) Lactate (C) Phosphoenolpyruvate (D) Enolpyruvate
Last Answer : Answer : A
Description : Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible: (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1, 6 diphosphate to ... phosphate (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Last Answer : Answer : C
Description : Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible. (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1,6-bisphosphate to fructose- ... (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate
Last Answer : B
Description : Which of the following enzymes incorporates inorganic phosphate into the substrate? (A) Phosphoglycerate kinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Enolase
Description : Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase
Description : In EM pathway -2-phosphoglycerate is converted to (A) Phospho enol pyruvate (B) Enol pyruvate (C) Di hydroxy acetone phosphate (DHAP) (D) 1,3 bisphosphoglycerate
Description : Phosphofructokinase is allosterically inhibited by (A) Fructose-1, 6-biphosphate (B) Lactate (C) Pyruvate (D) Citrate
Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate
Description : Adipose tissue which is a store house for triacyl glycerol synthesis the same using (A) The glycerol released by hydrolysis of triacyl glycerol (B) The glycerol-3-phosphate obtained in the metabolism of glucose (C) 2-phosphoglycerate (D) 3-phosphoglycerate
Last Answer : Answer : B
Description : Which of the following intermediates of metabolism can be both a precursor and a product of glucose? (A) Lactate (B) Pyruvate (C) Alanine (D) Acetyl-CoA
Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate
Description : Cori’s cycle transfers (A) Glucose from muscles to liver (B) Lactate from muscles to liver (C) Lactate from liver to muscles (D) Pyruvate from liver to muscles
Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase
Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Description : In the glycolytic pathway, enolpyruvate is converted to ketopyruvate by (A) Pyruvate kinase (B) Phosphoenolpyruvate (C) Pyruvate dehydrogenase (D) Spontaneously
Description : Which of the following enzymes in Glycolytic pathway is inhibited by fluoride? (A) Glyceraldehyde-3-p dehydrogenase (B) Phosphoglycerate kinase (C) Pyruvate kinase (D) Enolase
Last Answer : D
Description : A substrate for the enzyme aldolase is (A) galactose-6-phosphate (B) isocitric acid (C) Glucose-1-phosphate (D) Fructose 1, 6 diphosphate
Description : Hemolytic anemia is caused by the deficiency of certain enzymes of the pentose phosphate pathway, the principal enzyme involved is (A) Glucose-6-phosphate dehydrogenase (B) Aldolase (C) Fructose 1, 6-bisphosphatase (D) Phosphohexose isomerase
Description : Pentose phosphate pathway is of significance because it generates (A) NADPH for reductive synthesis (B) Regenerates glucose 6-phosphate (C) Generates fructose 6-phosphate (D) Forms glyceraldehyde 3-phosphate
Description : Hexokinase is inhibited in an allosteric manner by (A) Glucose-6-Phosphate (B) Glucose-1-Phosphate (C) Fructose-6-phosphate (D) Fructose-1, 6-biphosphate
Description : The following are true about the oxidation of glucose: a. glycolysis produces 3% of the energy ultimately obtained from glucose b. the first stage of glycolysis involves phosphorylation of glucose to 1,6-fructose biphosphate. c. glucose enters the Kreb's cycle as pyruvate d. all above
Last Answer : all above
Description : Glycerol can enter glycolytic pathway via (A) Dihydroxyacetone phosphate (B) 1, 3-Biphospoglycerate (C) 3-Phosphoglycerate (D) 2-Phosphoglycerate
Description : In erythrocytes, 2, 3-biphosphoglycerate is derived from the intermediate: (A) Glyeraldehyde-3-phosphate (B) 1, 3-Biphosphoglycerate (C) 3-Phosphoglycerate (D) 2-Phosphoglycerate
Description : Anion gap of plasma can be due to the presence of all the following except (A) Bicarbonate (B) Lactate (C) Pyruvate (D) Citrate
Description : Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase
Description : End product of aerobic glycolysis is (A) Acetyl CoA (B) Lactate (C) Pyruvate (D) CO2 and H2O
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Description : Compared to the resting state, vigorously contracting muscle shows (A) An increased conversion of pyruvate to lactate (B) Decreased oxidation of pyruvate of CO2 and water (C) A decreased NADH/NAD+ ratio (D) Decreased concentration of AMP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 21
Description : When O2 supply is inadequate, pyruvate is converted to (A) Phosphopyruvate (B) Acetyl CoA (C) Lactate (D) Alanine
Description : In which condition pyruvate is produced, and when lactate?
Last Answer : In aerobic condition pyruvate is produced. When oxygen is lacking, lactate is produced.
Description : The reaction catalysed by phosphofructokinase (A) Is activated by high concentrations of ATP and citrate (B) Uses fruitose-1-phosphate as substrate (C) Is the rate-limiting reaction of the glycolytic pathway (D) Is inhibited by fructose 2, 6-bisphosphate
Description : Which of the following statements about delivery-dependent oxygen consumption are true? A. Below the critical oxygen delivery (D(overdot)O 2crit), one would expect to see a decrease in the ... oxygen extraction ratio remains constant as long as oxygen delivery remains above D(overdot)O 2crit.
Last Answer : Answer: BC DISCUSSION: Oxygen consumption is said to be delivery dependent below a critical point, D(overdot)O 2crit, at which anaerobic metabolism supervenes. Above this point, oxygen ... the therapeutic benefit of trying to achieve supranormal oxygen delivery has not been firmly established
Description : Which of the metabolites is common to respiration- mediated breakdown of fats, carbohydrates and proteins? (a) Pyruvic acid (b) Acetyl CoA (c) Glucose - 6 - phosphate (d) Fructose 1, 6 - bisphosphate
Last Answer : (b) Acetyl CoA
Description : Which of the following biomolecules is common to respiration-mediated breakdown of fats, carbohydrates and proteins? (a) Glucose-6-phosphate (b) Fructose 1, 6-bisphosphate (c) Pyruvic acid (d) Acetyl CoA
Last Answer : d) Acetyl CoA
Description : Insulin increases the activity of (A) Pyruvate kinase (B) Phosphorylase (C) Triacylglycerol kinase (D) Fructose 2, 6-bisphosphatase
Description : Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6-biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase (D) Stimulation of synthesis of eltroxykinase
Description : The number of ATP molecules required to convert 2 molecules of lactate into glucose in mammalian liver is (A) 2 (B) 4 (C) 5 (D) 6
Description : End product of glycolysis is (a) acetyl CoA (b) pyruvic acid (c) glucose 1-phosphate (d) fructose 1-phosphate.
Last Answer : (b) pyruvic acid
Description : Quantitatively, the most significant buffer system in plasma is (A) Phosphate buffer system (B) Carbonic acid-bicarbonate buffer system (C) Lactic acid-lactate buffer system (D) Protein buffer system
Description : The main product of glycolysis under aerobic conditions is a. Pyruvate b. Lactate c. None of these d. Both a and b Ans: A 2. The protein moiety of an enzyme is known as a. Holo enzyme b. Apo enzyme c. Co enzyme d. Enzyme
Last Answer : Ans: B
Description : Fructose 2, 3 bi phosphate is a powerful allosteric activator of (A) Fructose 1, 6 diphosphatase (B) Phosphofructokinase (C) Hexokinase (D) Fructokinase
Description : Which one of the following metabolites is not directly produced in the hexose monophosphate pathway? (A) Fructose-6-phosphate (B) Dihydroxy acetone phosphate (C) CO2 (D) Erythrose-4-phosphate
Description : Glucose 6-phosphate is converted to glucose 1-phosphate in a reaction catalysed by the enzyme phosphoglucomutase, which is (A) Phosphorylated (B) Dephosphorylated (C) Phosphorylated-dephosphorylated (D) Phosphorylated-dephosphorylatedrephosphorylated
Description : In the reaction below, Nu TP stands for NuTP + glucose → Glucose 6–Phosphate + NuDP. (A) ATP (B) CTP (C) GTP (D) UTP
Description : Glucose cannot be synthesized from (A) Glycerol (B) Lactate (C) Alanine (D) Leucine