Description : In the glycolytic pathway, enolpyruvate is converted to ketopyruvate by (A) Pyruvate kinase (B) Phosphoenolpyruvate (C) Pyruvate dehydrogenase (D) Spontaneously
Last Answer : Answer : D
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Last Answer : Answer : B
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Description : End product of aerobic glycolysis is (A) Acetyl CoA (B) Lactate (C) Pyruvate (D) CO2 and H2O
Last Answer : Answer : C
Description : Which of the following intermediates of metabolism can be both a precursor and a product of glucose? (A) Lactate (B) Pyruvate (C) Alanine (D) Acetyl-CoA
Last Answer : Answer : A
Description : When O2 supply is inadequate, pyruvate is converted to (A) Phosphopyruvate (B) Acetyl CoA (C) Lactate (D) Alanine
Last Answer : C
Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate
Last Answer : A
Description : Thiamine is essential for (A) Pyruvate dehydrogenase (B) Isocitrate dehydrogenase (C) Succinate dehydrogenase (D) Acetyl CoA synthetase ENZYMES 165
Description : An allosteric inhibitor of pyruvate dehydrogenase is (A) Acetyl CoA (B) ATP (C) NADH (D) Pyruvate
Description : Conversion of pyruvate into acetyl CoA is catalysed by (A) Pyruvate dehydrogenase (B) Didrolipoyl acetyl transferase (C) Dihydrolipoyl dehydrogenase (D) All the 3 acting in concert
Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase
Description : A reaction which may be considered an isomerisation is (A) Glucose 6-Phosphate fructose 6 phosphate (B) 3-Phosphoglycerate 2-phosphoglycerate (C) 2-phosphoglycerate phosphoenolpyruvate (D) Pyruvate Lactate
Description : Erythrocytes under normal conditions and microorganisms under anaerobic conditions may accumulate (A) NADPH (B) Pyruvate (C) Phosphoenolpyruvate (D) Lactate
Description : Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase
Description : A flavoprotein in pyruvate dehydrogenase complex is (A) Pyruvate dehydrogenase (B) Didrolipoyl acetyl transferase (C) Dihydrolipoyl dehydrogenase (D) None of these ENZYMES 161
Description : Acetyl CoA required for de novo synthesis of fatty acids is obtained from (A) Breakdown of existing fatty acids (B) Ketone bodies (C) Acetate (D) Pyruvate
Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate
Description : Which one of the following compounds cannot give rise to the net synthesis of Glucose? (A) Lactate (B) Glycerol (C) α-ketoglutarate (D) Acetyl CoA
Last Answer : B
Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate
Description : Pyruvate dehydrogenase contains all except (A) Biotin (B) NAD (C) FAD (D) CoA
Description : All the following are coenzymes except (A) Ubiquinone (B) CoA (C) Pyruvate dehydrogenase (D) Lipoic acid
Description : Pyruvate is converted into acetyl-CoA by (A) Decarboxylation (B) Dehydrogenation (C) Oxidative decarboxylation (D) Oxidative deamination
Description : Acetyl-CoA can be formed from (A) Pyruvate (B) Fatty acids (C) ketone bodies (D) All of these
Description : Carboxylation of acetyl-CoA to malonylCoA requires the enzyme: (A) Acetyl-CoA carboxylase (B) Pyruvate carboxylase (C) Acetyl transacylase (D) Acyl CoA-synthetase
Description : The coenzyme not involved in the formation of acetyl-CoA from pyruvate is (A) TPP (B) Biotin (C) NAD (D) FAD
Description : Fully activated pyruvate carboxylase depends upon the presence of (A) Malate and Niacin (B) Acetyl CoA and biotin (C) Acetyl CoA and thiamine pyrophosphate (D) Oxaloacetate and biotin
Description : Biotin is a coenzyme for (A) Pyruvate carboxylase (B) Acetyl CoA carboxylase (C) Propionyl CoA carboxylase (D) All of these
Description : Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible: (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1, 6 diphosphate to ... phosphate (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : While citrate is converted to isocitrate in the mitochondria, it is converted to _______ in the cytosol. (A) Acetyl CoA + oxaloacetate (B) Acetyl CoA + malonyl CoA (C) Acetyl CoA + Pyruvate (D) Acetyl CoA + acetoacetyl CoA
Description : Acetyl CoA formed from pyruvate can be used for the synthesis of all the following except (A) Glucose (B) Fatty acids (C) Cholesterol (D) Steroid hormones
Description : The conversion of pyruvate to acetyl CoA and CO2 (A) Is reversible (B) Involves the participation of lipoic acid (C) Depends on the coenzyme biotin (D) Occurs in the cytosol
Description : Which of the following compound is a positive allosteric modifier of the enzyme pyruvate carboxylase? (A) Biotin (B) Acetyl CoA (C) Oxaloacetate (D) ATP
Description : Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible. (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1,6-bisphosphate to fructose- ... (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : Pyruvate is converted to acetyl CoA by which enzyme?
Last Answer : Pyruvate dehydrogenate.
Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Description : Alcohol dehydrogenase converts ethanol into (A) Acetyl CoA (B) Acetaldehyde (C) Acetate (D) CO2 and H2O
Description : Two examples of substrate level phosphorylation in EM pathway of glucose metabolism are in the reactions of (A) 1,3 bisphosphoglycerate and phosphoenol pyruvate (B) Glucose-6 phosphate ... phosphate (C) 3 phosphoglyceraldehyde and phosphoenolpyruvate (D) 1,3 diphosphoglycerate and 2-phosphoglycerate
Description : In most metabolic pathways, all needed enzymes are arranged together in a multienzyme complex within a (A) Solution of ATP (B) Membrane (C) Quanternary protein (D) Coenzyme
Description : Pyruvate dehydrogenase complex is regulated by (A) Covalent modification (B) Allosteric regulation (C) Both (A) and (B) (D) None of these
Description : Pyruvate dehydrogenase complex is located in (A) Cytosol (B) Lysosomes (C) Mitochondria (D) Endoplasmic reticulum
Description : Pyruvate dehydrogenase complex and α-ketoglutarate dehydrogenase complex require the following for their oxidative decarboxylation: (A) COASH and Lipoic acid (B) NAD+ and FAD (C) COASH and TPP (D) COASH, TPP,NAD+,FAD, Lipoate
Last Answer : D
Description : Connecting link between glycolysis and Krebs’ cycle before pyruvate entering Krebs’ cycle is changed to (a) oxaloacetate (b) PEP (c) pyruvate (d) acetyl CoA.
Last Answer : (d) acetyl CoA.
Description : Mitochondrial α-ketoglutarate dehydrogenase complex requires all the following to function except (A) CoA (B) FAD (C) NAD+ (D) NADP+
Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex
Description : NAD is required as a coenzyme for (A) Malate dehydrogenase (B) Succinate dehydrogenase (C) Glucose-6-phosphate dehydrogenase (D) HMG CoA reductae
Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form
Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP
Description : Biotin is required for the reaction of CO2 with (A) Water (B) Acetyl CoA (C) NH3 (D) Incorporation of carbon 6 in purine