Description : All of the following intermediates of citric acid cycle can be formed from amino acids except (A) α-Ketoglutarate (B) Fumarate (C) Malate (D) Oxaloacetate
Last Answer : Answer : C
Description : The reaction of Kreb’s cycle which does not require cofactor of vitamin B group is (A) Citrate isocitrate (B) α -Ketoglutarate succinate (C) Malate oxaloacetate (D) Succinate fumarate
Last Answer : Answer : A
Description : The example of generation of a high energy phosphate at the substrate level in the citric acid cycle is the reaction: (A) Isocitrate α-Ketoglutarate (B) Succinate α-fumarate (C) Malate α-oxaloacetate (D) Succinyl CoA α-Succinate
Last Answer : Answer : D
Description : The substance which may be considered to play a catalytic role in citric acid cycle is (A) Oxaloacetate (B) Isocitrate (C) Malate (D) Fumarate
Description : The carrier of the citric acid cycle is (A) Succinate (B) Fumarate (C) Malate (D) Oxaloacetate
Last Answer : D
Description : The integrator between the TCA cycle and urea cycle is (A) Fumarate (B) Malate (C) Pyruvate (D) Citrate
Description : All of the following compounds are intermediates of TCA cycle except (A) Maleate (B) Pyruvate (C) Oxaloacetate (D) Fumarate
Last Answer : Answer : B
Description : All of the following are intermediates of citric acid cycle except (A) Oxalosuccinate (B) Oxaloacetate (C) Pyruvate (D) Fumarate
Description : Fully activated pyruvate carboxylase depends upon the presence of (A) Malate and Niacin (B) Acetyl CoA and biotin (C) Acetyl CoA and thiamine pyrophosphate (D) Oxaloacetate and biotin
Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier
Description : Fluoroacetate inhibits the reaction of citric acid cycle: (A) Isocitrate α-Ketoglutarate (B) Fumarate α-Malate (C) Citrate α-cis-aconitate (D) Succinate α-fumarate
Description : A compound serving a link between citric acid cycle and urea cycle is (A) Malate (B) Citrate (C) Succinate (D) Fumarate
Description : Out of 24 mols of ATP formed in TCA cycle, 2 molecules of ATP can be formed at “substrate level” by which of the following reaction ? (A) Citric acid→ Isocitric acid (B) Isocitrate→ Oxaloacetate (C) Succinic acid→ Fumarate (D) Succinylcat→ Succinic acid
Description : Active transport of sugar is depressed by the agent: (A) Oxaloacetate (B) Fumarate (C) Malonate (D) Succinate
Last Answer : C
Description : A carrier molecule in the citric acid cycle is (A) Acetyl-CoA (B) Citrate (C) Oxaloacetate (D) Malate
Description : The metabolism of protein is integrated with that of carbohydrate and fat through (A) Oxaloacetate (B) Citrate (C) Isocitrate (D) Malate
Description : A competitive inhibitor of succinic dehydrogenase is (a) α-ketoglutarate (b) malate (c) malonate (d) oxaloacetate.
Last Answer : (c) malonate
Description : Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Description : NADPH is produced when this enzyme acts (A) Pyruvate dehydrogenase (B) Malic enzyme (C) Succinate dehydrogenase (D) Malate dehydrogenase
Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate
Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase
Description : Pyridoxal phosphate is a coenzyme for (A) Glutamate oxaloacetate transaminase (B) Glutamate pyruvate transaminase (C) Tyrosine transaminase (D) All of these
Description : The coenzyme required for conversion of pyruvate to oxaloacetate is (A) FAD (B) NAD (C) TPP (D) Biotin
Description : While citrate is converted to isocitrate in the mitochondria, it is converted to _______ in the cytosol. (A) Acetyl CoA + oxaloacetate (B) Acetyl CoA + malonyl CoA (C) Acetyl CoA + Pyruvate (D) Acetyl CoA + acetoacetyl CoA
Description : Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate
Description : For conversion of oxaloacetate to phosphoenol pyruvate, high energy molecule is required in the form of (A) GTP only (B) ITP only (C) GTP (or) ITP (D) None of these
Description : In presence of the following cofactor, pyruvate carboxylase converts pyruvate to oxaloacetate: (A) ATP, Protein and CO2 (B) CO2 and ATP (C) CO2 (D) Protein
Last Answer : A
Description : Which of the following compound is a positive allosteric modifier of the enzyme pyruvate carboxylase? (A) Biotin (B) Acetyl CoA (C) Oxaloacetate (D) ATP
Description : An aneplerotic reaction which sustains the availability of oxaloacetate is the carboxylation of (A) Glutamate (B) Pyruvate (C) Citrate (D) Succinate
Last Answer : B
Description : Pyruvate carboxylase reaction (pyruvate to oxaloacetate) needs which co-enzyme?
Last Answer : Biotin and ATP.
Description : All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is (a) isocitrate dehydrogenase (b) malate dehydrogenase (c) succinate dehydrogenase (d) lactate dehydrogenase.
Last Answer : (c) succinate dehydrogenase
Description : Mitochondrial pyruvate carboxylase contains (A) Zinc (B) Zinc (C) Manganese (D) Magnesium
Description : Reducing equivalents from pyruvate enter the mitochondrial respiratory chain at (A) FMN (B) NAD (C) Coenzyme Q (D) Cyt b
Description : A mitochondrial marker enzyme is (A) Aldolase (B) Amylase (C) Succinic dehydrogenase (D) Pyruvate dehydrogenase ENZYMES 175
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : Connecting link between glycolysis and Krebs’ cycle before pyruvate entering Krebs’ cycle is changed to (a) oxaloacetate (b) PEP (c) pyruvate (d) acetyl CoA.
Last Answer : (d) acetyl CoA.
Description : In mitochondrial matrix complete oxidation of pyruvate takes place in which all the hydrogen atoms are removed, leaving three molecules of `CO_(2)`
Last Answer : In mitochondrial matrix complete oxidation of pyruvate takes place in which all the hydrogen atoms are removed, leaving three molecules of `CO_(2)`
Description : In mitochondrial matrix pyruvate undergoes_____
Last Answer : In mitochondrial matrix pyruvate undergoes_____
Description : Which of the following component of respiratory chain is not attached to the inner mitochondrial membrane? (A) Coenzyme Q (B) Cytochrome c (C) Both (A) and (B) (D) None of these
Description : The chemical inhibiting oxidative phosphorylation, Adependent on the transport of adenine nucleotides across the inner mitochondrial membrane is (A) Oligomycin (B) Atractyloside (C) Dinitrophenol (D) Pentachlorophenol
Description : The redox carriers are grouped into respiratory chain complex (A) In the inner mitochondrial membrane (B) In mitochondiral matrix (C) On the outer mitochondrial membrane (D) On the inner surface of outer mitochondrial membrane
Description : Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by (A) cAMP (B) Prostaglandin (C) Carnitine (D) Choline
Description : Mitochondrial membrane is permeable to (A) Short chain fatty acids (B) Medium chain fatty acids (C) Long chain fatty acids (D) All of these
Description : Carnitine acylcarnitine translocase is present (A) In the inner mitochondrial membrane (B) In the mitochondrial matrix (C) On the outer surface of inner mitochondrial membrane (D) On the inner surface of inner mitochondrial membrane
Description : Oxidation of fatty acids occurs (A) In the cytosol (B) In the matrix of mitochondria (C) On inner mitochondrial membrane (D) On the microsomes
Description : All of the following statements about the enzymic complex that carries out the synthesis of ATP during oxidative phosphorylation are correct except (A) It is located on the matrix side of the inner ... inhibited by oligomycin (C) It can exhibit ATPase activity (D) It can bind molecular O2
Description : Electron transport and phosphorylation can be uncoupled by compounds that increase the permeability of the inner mitochondrial membrane to (A) Electrons (B) Protons (C) Uncouplers (D) All of these