Ketosis reflects (A) Increased hepatic glucose liberation (B) Increased fatty acid oxidation (C) Increased carbohydrate utilisation (D) Incresed gluconeogenesis

Ketosis reflects (A) Increased hepatic glucose liberation (B) Increased fatty acid oxidation (C) Increased carbohydrate utilisation (D) Incresed gluconeogenesis
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Ketosis in partly ascribed to (A) Over production and Glucose (B) Under production of Glucose (C) Increased carbohydrate utilization (D) Increased fat utilization

Description : Ketosis in partly ascribed to (A) Over production and Glucose (B) Under production of Glucose (C) Increased carbohydrate utilization (D) Increased fat utilization

Last Answer : Answer : D

Growth hormone causes hyperglycemia. It is a result of (A) Decreased peripheral utilization of glucose (B) Decreased hepatic production via gluconeogenesis (C) Increased glycolysis in muscle (D) Decrersed lipolysis

Description : Growth hormone causes hyperglycemia. It is a result of (A) Decreased peripheral utilization of glucose (B) Decreased hepatic production via gluconeogenesis (C) Increased glycolysis in muscle (D) Decrersed lipolysis

Last Answer : Answer : A

A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic hormone (ACTH) is secreted from the anterior pituitary gland b. ACTH stimulation results in elevation of serum cortisol levels for up to a week after the operation c. An increased secretion of aldosterone and ADH may contribute to postoperative fluid retention d. An increase in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis

Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis

Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained

Metabolic acidosis is caused in (A) Uncontrolled diabetes with ketosis (B) Pneumonia (C) Intestinal Obstruction (D) Hepatic coma

Description : Metabolic acidosis is caused in (A) Uncontrolled diabetes with ketosis (B) Pneumonia (C) Intestinal Obstruction (D) Hepatic coma

Last Answer : Answer : A

The glycerol for fatty acid esterification in adipocytes is (A) For the most part, derived from glucose (B) Obtained primarily from phosphorylation of glycerol by glycerol kinase (C) Formed from gluconeogenesis (D) Formed from glycogenolysis ENZYMES 153

Description : The glycerol for fatty acid esterification in adipocytes is (A) For the most part, derived from glucose (B) Obtained primarily from phosphorylation of glycerol by glycerol kinase (C) Formed from gluconeogenesis (D) Formed from glycogenolysis ENZYMES 153

Last Answer : Answer : A

The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD

Description : The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD

Last Answer : A

Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct

Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct

Last Answer : D. Both A and B are correct

Renal glycosuria is characterized by (A) Hyperglycemia (B) Hyperglycemia with glycosuria (C) Normal blood glucose level with glycosuria (D) Hyperglycemia with ketosis

Description : Renal glycosuria is characterized by (A) Hyperglycemia (B) Hyperglycemia with glycosuria (C) Normal blood glucose level with glycosuria (D) Hyperglycemia with ketosis

Last Answer : Answer : C

Glucocorticoids increase all of the following except (A) Gluconeogenesis (B) Lipolysis in extremities (C) Synthesis of elcosanoida (D) Hepatic glycogenesis

Description : Glucocorticoids increase all of the following except (A) Gluconeogenesis (B) Lipolysis in extremities (C) Synthesis of elcosanoida (D) Hepatic glycogenesis

Last Answer : Answer : C

Insulin stimulates (A) Hepatic glycogenolysis (B) Hepatic glycogenesis (C) Lipolysis (D) Gluconeogenesis

Description : Insulin stimulates (A) Hepatic glycogenolysis (B) Hepatic glycogenesis (C) Lipolysis (D) Gluconeogenesis

Last Answer : Answer : B

Link between glycolysis, Krebs’ cycle and β-oxidation of fatty acid or carbohydrate and fat metabolism is (a) oxaloacetic acid (b) succinic acid (c) citric acid (d) acetyl CoA.

Description : Link between glycolysis, Krebs’ cycle and β-oxidation of fatty acid or carbohydrate and fat metabolism is (a) oxaloacetic acid (b) succinic acid (c) citric acid (d) acetyl CoA.

Last Answer : (d) acetyl CoA.

A 59-year-old trauma patient has suffered multiple septic complications including severe pneumonia, intraabdominal abscess, and major wound infection. He has now developed signs of multisystem organ failure. Which of the following statement(s) is/are true concerning necessary changes to be made in his nutritional management? a. Carbohydrate load should be reduced in the face of respiratory failure b. In patients with renal failure, protein intake should be diminished c. During hemodialysis protein intake should be limited to the same extent d. In patients with hepatic failure, carbohydrate load should be increased

Description : A 59-year-old trauma patient has suffered multiple septic complications including severe pneumonia, intraabdominal abscess, and major wound infection. He has now developed signs of multisystem organ ... the same extent d. In patients with hepatic failure, carbohydrate load should be increased

Last Answer : Answer: a, b The most severe complication of sepsis is multiple system organ dysfunction syndrome, which may result in death. The development of organ failure requires changes in the ... should be provided as fat emulsion. If encephalopathy develops, protein load should also be reduced0

The rate of fatty acid oxidation is increased by (A) Phospholipids (B) Glycolipids (C) Aminolipids (D) All of these

Description : The rate of fatty acid oxidation is increased by (A) Phospholipids (B) Glycolipids (C) Aminolipids (D) All of these

Last Answer : Answer : A

Conversion of Alanine to carbohydrate is termed: (A) Glycogenesis (B) Gluconeogenesis (C) Glycogenolysis (D) Photosynthesis

Description : Conversion of Alanine to carbohydrate is termed: (A) Glycogenesis (B) Gluconeogenesis (C) Glycogenolysis (D) Photosynthesis

Last Answer : B

What are those non-carbohydrate sources? (What are the substrates for gluconeogenesis?).

Description : What are those non-carbohydrate sources? (What are the substrates for gluconeogenesis?). 

Last Answer : Glucogenic amino acids and lactate. 

Compared to the resting state, vigorously contracting muscle shows (A) An increased conversion of pyruvate to lactate (B) Decreased oxidation of pyruvate of CO2 and water (C) A decreased NADH/NAD+ ratio (D) Decreased concentration of AMP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 21

Description : Compared to the resting state, vigorously contracting muscle shows (A) An increased conversion of pyruvate to lactate (B) Decreased oxidation of pyruvate of CO2 and water (C) A decreased NADH/NAD+ ratio (D) Decreased concentration of AMP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 21

Last Answer : A

All the following statements about brown adipose tissue are true except (A) It is rich in cytochromes (B) It oxidizes glucose and fatty acids (C) Oxidation and phosphorylation are tightly coupled in it (D) Dinitrophenol has no effect on it

Description : All the following statements about brown adipose tissue are true except (A) It is rich in cytochromes (B) It oxidizes glucose and fatty acids (C) Oxidation and phosphorylation are tightly coupled in it (D) Dinitrophenol has no effect on it

Last Answer : Answer : C

True statements about aldosterone include: a. secretion is mainly under the control of adrenocorticotrophic (ACTH) hormone secretion b. increases hepatic gluconeogenesis c. its secretion is stimulated by angiotensin d. in the kidney, mainly acts on the proximal convoluted tubules

Description : True statements about aldosterone include: a. secretion is mainly under the control of adrenocorticotrophic (ACTH) hormone secretion b. increases hepatic gluconeogenesis c. its secretion is stimulated by angiotensin d. in the kidney, mainly acts on the proximal convoluted tubules

Last Answer : its secretion is stimulated by angiotensin

Impaired galactose tolerance test suggests (A) Defect in glucose utilisation (B) Liver cell injury (C) Renal defect (D) Muscle injury

Description : Impaired galactose tolerance test suggests (A) Defect in glucose utilisation (B) Liver cell injury (C) Renal defect (D) Muscle injury

Last Answer : Answer : B

Maximum glucose utilisation is seen in which tissue?

Description : Maximum glucose utilisation is seen in which tissue?

Last Answer : At basal rates, brain utilises 60% of sugar oxidised.

The acquisition energy by glucose fermentation requires A.substrate-level phosphorylation B.electron transport of electrons from NADH C.long-chain fatty acid oxidation D.the enzyme formic-hydrogen lyase

Description : The acquisition energy by glucose fermentation requires A.substrate-level phosphorylation B.electron transport of electrons from NADH C.long-chain fatty acid oxidation D.the enzyme formic-hydrogen lyase

Last Answer : A.substrate-level phosphorylation

Most of the energy in aerobic respiration of glucose is captured by A- substrate-level phosphorylation B- electron transport of electrons from NADH C- long-chain fatty acid oxidation D- the enzyme formic-hydrogen lyase

Description : Most of the energy in aerobic respiration of glucose is captured by A- substrate-level phosphorylation B- electron transport of electrons from NADH C- long-chain fatty acid oxidation D- the enzyme formic-hydrogen lyase

Last Answer : electron transport of electrons from NADH

De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by insulin (C) NADH is required in synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis

Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis

Last Answer : Answer : A

Which of the following statement(s) is/are true concerning metabolic derangements in sepsis and the systemic inflammatory response syndrome which may follow progressive shock? a. Alterations in glucose metabolism lead to the development of efficient substrate utilization b. A progressive rise in serum triglyceride levels result from less efficient clearance and increased hepatic lipogenesis c. A net negative nitrogen balance occurs due to the oxidative metabolism of proteins to meet energy needs d. The serum aromatic amino acids fall rapidly as they are actively used in oxidative metabolism

Description : Which of the following statement(s) is/are true concerning metabolic derangements in sepsis and the systemic inflammatory response syndrome which may follow progressive shock? a. Alterations in glucose ... The serum aromatic amino acids fall rapidly as they are actively used in oxidative metabolism

Last Answer : Answer: b, c A broad spectrum of metabolic abnormalities become apparent in sepsis and the systemic inflammatory response syndrome following shock. Disruption of the normal cycles of carbohydrate, ... acetyl coenzyme A. This results in reduced serum level of leucine, isoleucine and valine

The level of free fatty acids in plasma is increased by (A) Insulin (B) Caffeine (C) Glucose (D) Niacin

Description : The level of free fatty acids in plasma is increased by (A) Insulin (B) Caffeine (C) Glucose (D) Niacin

Last Answer : Answer : B

Which of the following products of triacylglycerol breakdown and subsequent β-Oxidation may undergo gluconeogenesis? (A) Acetyl CoA (B) Porpionyl CoA (C) All ketone bodies (D) Some amino acids

Description : Which of the following products of triacylglycerol breakdown and subsequent β-Oxidation may undergo gluconeogenesis? (A) Acetyl CoA (B) Porpionyl CoA (C) All ketone bodies (D) Some amino acids

Last Answer : Answer : B

Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis

Description : Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis

Last Answer : Answer : D

Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt

Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt

Last Answer : Answer : C

Insulin increases (A) Glycogenesis (B) Gluconeogenesis (C) Lipolysis (D) Blood glucose

Description : Insulin increases (A) Glycogenesis (B) Gluconeogenesis (C) Lipolysis (D) Blood glucose

Last Answer : Answer : A

Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose

Description : Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose

Last Answer : Answer : C

Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis

Description : Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis

Last Answer : Answer : A

The process of breakdown of glycogen to glucose in the liver and pyruvate and lacate in the muscle is known as (A) Glyogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Cellular degradation

Description : The process of breakdown of glycogen to glucose in the liver and pyruvate and lacate in the muscle is known as (A) Glyogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Cellular degradation

Last Answer : Answer : B

Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate

Description : Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate

Last Answer : C

Synthesis of Glucose from amino acids is termed as (A) Glycolysis (B) Gluconeogenesis (C) Glycogenesis (D) Lipogenesis

Description : Synthesis of Glucose from amino acids is termed as (A) Glycolysis (B) Gluconeogenesis (C) Glycogenesis (D) Lipogenesis

Last Answer : B

The conversion of alanine to glucose is termed (A) Glycolysis (B) Oxidative decarboxylation (C) Specific dynamic action (D) Gluconeogenesis

Description : The conversion of alanine to glucose is termed (A) Glycolysis (B) Oxidative decarboxylation (C) Specific dynamic action (D) Gluconeogenesis

Last Answer : D

Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate

Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate

Last Answer : C

Blood glucose level can be raised by gluconeogenesis only by liver, why?

Description : Blood glucose level can be raised by gluconeogenesis only by liver, why?

Last Answer : Glucose-6-phosphatase is present only in liver.

An essential for converting Glucose to Glycogen in Liver is (A) Lactic acid (B) GTP (C) CTP (D) UTP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 19

Description : An essential for converting Glucose to Glycogen in Liver is (A) Lactic acid (B) GTP (C) CTP (D) UTP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 19

Last Answer : D

16.3 Actions of growth hormone include the following except: A. Increased protein synthesis B. Increased fat utilization C. Increased carbohydrate utilization D. Glucose intolerance

Description : 16.3 Actions of growth hormone include the following except: A. Increased protein synthesis B. Increased fat utilization C. Increased carbohydrate utilization D. Glucose intolerance

Last Answer : C. Increased carbohydrate utilization

Ketosis is associated with the disease: (A) Nephritis (B) Diabetes mellitus (C) Edema (D) Coronary artery diseases

Description : Ketosis is associated with the disease: (A) Nephritis (B) Diabetes mellitus (C) Edema (D) Coronary artery diseases

Last Answer : Answer : B

Ketosis is due to what processes?

Description : Ketosis is due to what processes?

Last Answer : Step 1: Absence of insulin leads to excessive hydrolysis of triacyl glycerol. Step 2: So more fatty acid is available, and more acetyl CoA is produced. Step 3: But oxidation of acetyl CoA in citric acid cycle is sluggish. The excess acetyl CoA is diverted into ketone body formation.

The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis

Description : The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis

Last Answer : B

Two conditions in which gluconeogenesis is increased are (A) Diabetes mellitus and atherosclerosis (B) Fed condition and thyrotoxicosis (C) Diabetes mellitus and Starvation (D) Alcohol intake and cigarette smoking

Description : Two conditions in which gluconeogenesis is increased are (A) Diabetes mellitus and atherosclerosis (B) Fed condition and thyrotoxicosis (C) Diabetes mellitus and Starvation (D) Alcohol intake and cigarette smoking

Last Answer : C

Gluconeogenesis is increased in the following condition: (A) Diabetes insipidus (B) Diabetes Mellitus (C) Hypothyroidism (D) Liver diseases

Description : Gluconeogenesis is increased in the following condition: (A) Diabetes insipidus (B) Diabetes Mellitus (C) Hypothyroidism (D) Liver diseases

Last Answer : B

Increased carbohydrate consumption increases the dietary requirement for (A) Thiamine (B) Riboflavine (C) Pyridoxine (D) Folic acid

Description : Increased carbohydrate consumption increases the dietary requirement for (A) Thiamine (B) Riboflavine (C) Pyridoxine (D) Folic acid

Last Answer : Answer : A

NAD is required as a conenzyme in (A) Citric acid cycle (B) HMP shunt (C) β-Oxidation of fatty acids (D) Both (A) and (C)

Description : NAD is required as a conenzyme in (A) Citric acid cycle (B) HMP shunt (C) β-Oxidation of fatty acids (D) Both (A) and (C)

Last Answer : Answer : D

Vitamin K is a cofactor for (A) Gamma carboxylation of glutamic acid residue (B) β-Oxidation of fatty acid (C) Formation of γ-amino butyrate (D) Synthesis of tryptophan

Description : Vitamin K is a cofactor for (A) Gamma carboxylation of glutamic acid residue (B) β-Oxidation of fatty acid (C) Formation of γ-amino butyrate (D) Synthesis of tryptophan

Last Answer : Answer : A

During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103

Description : During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103

Last Answer : Answer : A

β-Oxidation of odd-carbon fatty acid chain produces (A) Succinyl CoA (B) Propionyl CoA (C) Acetyl CoA (D) Malonyl CoA

Description : β-Oxidation of odd-carbon fatty acid chain produces (A) Succinyl CoA (B) Propionyl CoA (C) Acetyl CoA (D) Malonyl CoA

Last Answer : Answer : D