Description : Chain elongation of fatty acids occurring in mammalian liver takes place in which of the following subcellular fractions of the cell? (A) Nucleus (B) Ribosomes (C) Lysosomes (D) Microsomes
Last Answer : Answer : D
Description : The major site for elongation of medium chain fatty acids is (A) Mitochondria (B) Cytosol (C) Microsomes (D) All of these
Last Answer : Answer : C
Description : Long chain fatty acids are first activated to acetyl-CoA in (A) Cytosol (B) Microsomes (C) Nucleus (D) Mitochondria
Last Answer : Answer : A
Description : The main pathway for denovo synthesis of fatty acids occur in (A) Cytosol (B) Mitochondria (C) Microsomes (D) Nucleus
Description : Oxidation of fatty acids occurs (A) In the cytosol (B) In the matrix of mitochondria (C) On inner mitochondrial membrane (D) On the microsomes
Last Answer : Answer : B
Description : De hovo synthesis of fatty acids occurs in (A) Cytosol (B) Mitochondria (C) Microsomes (D) All of these
Description : The biosynthesis of Urea occurs mainly in the Liver: (A) Cytosol (B) Microsomes (C) Nucleus (D) Mitochondria
Description : Epinephrine increases the concentration of free fatty acids in plasma by increasing (A) Extramitochondrial fatty acid synthesis (B) Mitochondrial fatty acid chain elongation (C) Microsomal fatty acid chain elongation (D) Lipolysis in adipose tissue
Description : The desaturation and chain elongation system of polyunsaturated fatty acids are greatly diminished in the absence of (A) Insulin (B) Glycagon (C) Epinephrine (D) Thyroxine
Description : C22 and C24, fatty acids required for the synthesis of sphingolipids in brain are formed by (A) De novo synthesis (B) Microsomal chain elongation (C) Mitochondrial chain elongation (D) All of these
Description : De novo synthesis of pyrimidine nucleotides occurs in (A) Mitochondria (B) Cytosol (C) Microsomes (D) Ribosomes
Description : Long chain fatty acids are first activated to acyl CoA in the (A) Cytosol (B) Mitochodria (C) Ribosomes (D) Microsome
Description : Oxidative conversion of many amino acids to their corresponding -ketoacids occurs in mammalian: (A) Liver and kidney (B) Adipose tissue (C) Pancreas (D) Intestine
Description : Lactate dehydrogenase is located in (A) Lysosomes (B) Mitochondria (C) Cytosol (D) Microsomes
Description : The biosynthesis of urea occurs mainly in the liver: (A) Cytosol (B) Mitochondria (C) Microsomes (D) Nuclei
Description : A soluble system for synthesis of fatty acids have been isolated from avian liver, required for the formation of long chain fatty acids by this system is (A) ATP (B) Acetyl CoA (C) NADPH (D) All of these
Description : Carnitine is required for the transport of (A) Triglycerides out of liver (B) Triglycerides into mitochondria (C) Short chain fatty acids into mitochondria (D) Long chain fatty acids into mitochondria
Description : The desaturation and chain elongation system of polyunsaturated fatty acid are enhanced by (A) Insulin (B) Glucagon (C) Epinephrine (D) Thyroxine
Description : Chain elongation of fatty acid is taking place in which site?
Last Answer : Microsomal elongation system is more active.
Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form
Description : α-Oxidation of fatty acids occurs mainly in (A) Liver (B) Brain (C) Muscles (D) Adipose tissue
Description : The site of enzymes directing the metabolic oxidation (respiration), ATP synthesis and considered as power house of cell are (A) Lysosomes (B) Microsomes (C) Mitochondria (D) Golgi apparatus
Last Answer : (C) Mitochondria
Description : The synthesis of 3-hydroxy-3-methylglutaryl-CoA can occur (A) Only in mitochondria of all mammalian tissues (B) Only in the cytosol of all mammalian tissue (C) In both cytosol and mitochondria (D) In lysosomes
Description : Monooxygenases are found in (A) Cytosol (B) Nucleus (C) Mitochondira (D) Microsomes
Description : Glycolytic pathway is located in (A) Mitochondria (B) Cytosol (C) Microsomes (D) Nucleus
Description : In eukaryotic cells (A) Formylated tRNA is important for initiation of translation (B) Cyclohexamide blocks elongation during translation (C) Cytosolic ribosomes are smaller than those found in prokaryotes (D) Erythromycin inhibits elongation during translation
Description : Extranuclear DNA is present in (A) Ribosomes (B) Endoplasmic reticulum (C) Lysosomes (D) Mitochondria
Description : In cell, digestive enzymes are found mainly in (A) Vacuoles (B) Lysosomes (C) Ribosomes (D) Lomasomes
Description : The d igest ive enzymes of ce l lu lar compounds are confined to (A) Lysosomes (B) Ribosomes (C) Peroxisomes (D) Polysomes
Last Answer : A
Description : Enzymes catalyzing electron transport are present mainly in the (A) Ribosomes (B) Endoplasmic reticulum (C) Lysosomes (D) Inner mitochondrial membrane
Last Answer : D
Description : The cellular organelles called “suicide bags” are (A) Lysosomes (B) Ribosomes (C) Nucleolus (D) Golgi’s bodies
Description : What is the sub cellular site for the βoxidation of fatty acids? (A) Nucleus (B) Mitochondria (C) Lysosome (D) Cytosol
Description : The second maturation division of the mammalian ovum occurs (a) shortly after ovulation before the ovum makes entry into the fallopian tube (b) until after the ovum has been penetrated by a sperm ... with that of the ovum (d) in the Graafian follicle following the first maturation division.
Last Answer : (b) until after the ovum has been penetrated by a sperm
Description : Fatty liver is caused due to accumulation of (A) Fatty acids (B) Cholesterol (C) Phospholipids (D) Triacylglycerol
Description : Retinal exists as an ester with higher fatty acids in the (A) Liver (B) Kidney (C) Lung (D) All of these
Description : The enzyme systems for lengthening and shortening for saturating and desaturating of fatty acids occur in (A) Intestine (B) Muscle (C) Kidney (D) Liver
Description : The maximum possible chain length of fatty acids formed in the pathway of de novo synthesis is (A) 16 Carbon atoms (B) 18 Carbon atoms (C) 20 Carbon atoms (D) 24 Carbon atoms
Description : The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to (A) CO2 and water (B) Cholesterol (C) Fatty acids (D) Ketone bodies
Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Description : All long chain fatty acids with even number of carbon atoms are oxidized to a pool of _________ by β-oxidation. (A) CO2 (B) Propionic acid (C) Acetic acid (D) Acetyl CoA
Description : Fatty acids having chain length of 10 carbon atoms enter the (A) Portal ciruclation (B) Lacteals (C) Systemic circulation (D) Colon
Description : For the activation of long chain fatty acids the enzyme thiokinase requires the cofactor: (A) Mg++ (B) Ca++ (C) Mn++ (D) K+
Description : All of the following statements about hypoglycin are true except (A) It is a plant toxin (B) It causes hypoglycaemia (C) It inhibits oxidation of short chain fatty acids (D) It inhibits oxidation of long chain fatty acids
Description : Mitochondrial membrane is permeable to (A) Short chain fatty acids (B) Medium chain fatty acids (C) Long chain fatty acids (D) All of these
Description : Mitochondrial thiokinase acts on (A) Short chain of fatty acids (B) Medium chain fatty acids (C) Long chain fatty acids (D) All of these
Description : Saliva contains a lipase which acts on triglycerides having (A) Short chain fatty acids (B) Medium chain fatty acids (C) Long chain fatty acids (D) All of these
Description : All the following statements about carnitine are true except (A) It can be synthesised in the human body (B) It can be synthesized from methionine and lysine (C) It is required for transport of short chain fatty acids into mitochondria (D) Its deficiency can occur due to haemodialysis
Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier
Description : What is the product of beta oxidation of odd chain fatty acids?
Last Answer : Propionyl CoA.
Description : What about medium and small chain fatty acids?
Last Answer : Medium chain fatty acids do not require carnitine for transport, so they are easily oxidised.