Description : Fatty acids with odd number of carbon atoms yield acetyl-CoA and a molecule of (A) Succinyl-CoA (B) Propionyl-CoA (C) Malonyl-CoA (D) Acetoacetyl-CoA
Last Answer : Answer : B
Description : β-Oxidation of odd-carbon fatty acid chain produces (A) Succinyl CoA (B) Propionyl CoA (C) Acetyl CoA (D) Malonyl CoA
Last Answer : Answer : D
Description : In extra hepatic tissues, one mechanism for utilization of acetoacetate involves (A) Malonyl-CoA (B) Succinyl-CoA (C) Propionyl-CoA (D) Acetyl-CoA
Description : Ceramide is formed by the combination of sphingosine and (A) Acetyl-CoA (B) Acyl-CoA (C) Malonyl-CoA (D) Propionyl-CoA
Description : The source of all the carbon atoms in cholesterol is (A) Acetyl-CoA (B) Bicarbonate (C) Propionyl-CoA (D) Succinyl-CoA
Last Answer : Answer : A
Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Description : Propionyl CoA formed oxidation of fatty acids having an odd number of carbon atoms is converted into (A) Acetyl CoA (B) Acetoacetyl CoA (C) D-Methylmalonyl CoA (D) Butyryl CoA
Last Answer : Answer : C
Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity
Description : In the extra mitochondrial synthesis of fatty acids, CO2 is utilized (A) To keep the system anaerobic and prevent regeneration of acetyl CoA (B) In the conversion of malonyl to CoA hydroxybutyryl CoA (C ... of acetyl CoA to malonyl CoA (D) In the formation of acetyl CoA from 1 carbon intermediates
Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP
Description : Which of the following cofactors or their derivatives must be present for the conversion of acetyl CoA to malonyl CoA extramitochondrial fatty acid synthesis? (A) Biotin (B) FAD (C) FMN (D) ACP
Description : What are the co-enzymes required for the conversion of propionyl CoA to succinyl CoA?
Last Answer : Biotin, ATP, Vitamin B12.
Description : As a result of each oxidation a long chain fatty acid is cleaved to give (A) An acid with 3-carbon less and propionyl CoA (B) An acid with 2-carbon less and acetyl CoA (C) An acid with 2-carbon less and acetyl CoA (D) An acid with 4-carbon and butyryl CoA
Description : The starting material for ketogenesis is (A) Acyl-CoA (B) Acetyl-CoA (C) Acetoacetyl-CoA (D) Malonyl-CoA
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : The protein, which is in fact a multifunctional enzyme complex in higher organism is (A) Acetyl transacylase (B) Malonyl transacylase (C) 3-Hydroxy acyl-ACP dehyratase (D) Fatty acid synthase
Description : Propionyl CoA is formed on oxidation of (A) Monounsaturated fatty acids (B) Polyunsaturated fatty acids (C) Fatty acids with odd number of carbon atoms (D) None of these FATS AND FATTY ACID METABOLISM 83
Description : β-oxidation of fatty acids is inhibited by (A) NADPH (B) Acetyl CoA (C) Malonyl CoA (D) None of these
Description : Which one of the following cofactors must be utilized during the conversion of acetyl CoA to malonyl CoA? (A) TPP (B) ACP (C) NAD+ (D) Biotin
Description : FAD containing enzyme, catalyzing formation of α, β unsaturated fatty acyl CoA derivative. (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thiolase
Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier
Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex
Description : During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : Which statement is wrong for Krebs' cycle? (a) There is one point in the cycle where FAD+ is reduced to FADH2. (b) During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised. (c ... citric acid. (d) There are three points in the cycle where NAD+ is reduced to NADH + H+.
Last Answer : (c) The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid.
Description : The cofactor or its derivative required for the conversion of acetyl CoA to malonylCoA is (A) FAD (B) ACP (C) NAD+ (D) Biotin
Description : All long chain fatty acids with even number of carbon atoms are oxidized to a pool of _________ by β-oxidation. (A) CO2 (B) Propionic acid (C) Acetic acid (D) Acetyl CoA
Description : Synthesis of polyunsaturated fatty acids involves the enzyme systems: (A) Acyl transferase and hydratase (B) Desaturase and elongase (C) Ketoacyl-CoA reductase and hydratase (D) Dihydroxyacetone phosphate
Description : The enzyme acyl-CoA synthase catalyses the conversion of a fatty acid of an active fatty acid in the presence of (A) AMP (B) ADP (C) ATP (D) GTP
Description : Biotin is a coenzyme for (A) Pyruvate carboxylase (B) Acetyl CoA carboxylase (C) Propionyl CoA carboxylase (D) All of these
Description : While citrate is converted to isocitrate in the mitochondria, it is converted to _______ in the cytosol. (A) Acetyl CoA + oxaloacetate (B) Acetyl CoA + malonyl CoA (C) Acetyl CoA + Pyruvate (D) Acetyl CoA + acetoacetyl CoA
Description : Carboxylation of acetyl—CoA to malonyl — CoA takes place in presence of (A) FAD+ (B) Biotin (C) NAD+ (D) NADP+
Description : Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible: (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1, 6 diphosphate to ... phosphate (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible. (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1,6-bisphosphate to fructose- ... (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Last Answer : C
Description : The conversion of pyruvate to acetyl CoA and CO2 (A) Is reversible (B) Involves the participation of lipoic acid (C) Depends on the coenzyme biotin (D) Occurs in the cytosol
Last Answer : B
Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis
Description : Carboxylation of acetyl-CoA to malonylCoA requires the enzyme: (A) Acetyl-CoA carboxylase (B) Pyruvate carboxylase (C) Acetyl transacylase (D) Acyl CoA-synthetase
Description : In synthesis of Triglyceride from α-Glycero phosphate and acetyl CoA, the first intermediate formed is (A) β-diacyl glycerol (B) Acyl carnitine (C) Monoacyl glycerol(D) Phosphatidic acid
Description : This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP: (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thio kinase
Description : Both Acyl carrier protein (ACP) of fatty acid synthetase and coenzyme (CoA) are (A) Contain reactive phosphorylated (B) Contain thymidine (C) Contain phosphopantetheine reactive groups (D) Contain cystine reactive groups
Description : Intermediate in the denovo synthesis of triacyl glycerols include all the following except (A) Fatty acyl CoA (B) CDP diacyl glycerol (C) Glycerol-3-phosphate (D) Lysophosphatidic acid
Description : During each cycle of β-oxidation of fatty acid, all the following compounds are generated except (A) NADH (B) H2O (C) FAD (D) Acyl CoA
Description : Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by (A) cAMP (B) Prostaglandin (C) Carnitine (D) Choline
Description : Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+
Description : Long chain fatty acids are first activated to acyl CoA in the (A) Cytosol (B) Mitochodria (C) Ribosomes (D) Microsome
Description : In Krebs’ cycle, the FAD precipitates as electron acceptor during the conversion of (a) fumaric acid to malic acid (b) succinic acid to fumaric acid (c) succinyl CoA to succinic acid (d) α-ketoglutarate to succinyl CoA.
Last Answer : (b) succinic acid to fumaric acid
Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Description : Acetyl CoA required for de novo synthesis of fatty acids is obtained from (A) Breakdown of existing fatty acids (B) Ketone bodies (C) Acetate (D) Pyruvate
Description : Acetyl-CoA can be formed from (A) Pyruvate (B) Fatty acids (C) ketone bodies (D) All of these