Description : The enzyme deficient in Sandhoff’s disease is (A) α-Fucosidase (B) Hexosaminidase A and B (C) β-Galactosidase (D) β-Glucosidase
Last Answer : Answer : B
Description : Gaucher’s disease is due to the deficiency of the enzyme: (A) α-Fucosidase (B) β-Galactosidase (C) β-Glucosidase (D) Sphingomyelinase
Last Answer : Answer : C
Description : β -Galactosidase is deficient in (A) Fabry’s disease (B) Krabbe’s disease (C) Gaucher’s disease (D) Metachromatic leukodystrophy
Description : The enzyme deficient in Fabry’s disease is (A) α-Galactosidase (B) β-Galactosidase (C) α-Glucosidase (D) β-Glucosidase
Last Answer : Answer : A
Description : Krabbe’s disease is due to the deficiency of the enzyme: (A) Ceramide lactosidase (B) Ceramidase (C) β-Galactosidase (D) GM1 β-Galactosidase
Description : Metachromatic leukodystrophy is due to deficiency of enzyme: (A) α-Fucosidase (B) Arylsulphatase A (C) Ceramidase (D) Hexosaminidase A
Description : Wolman’s disease is due to deficiency of (A) Cholesteryl ester hydrolase (B) Hexosaminidase A (C) α-Fucosidase (D) Arylsulphatase A
Description : Farber’s disease is due to the deficiency of the enzyme: (A) α-Galactosidase (B) Ceramidase (C) β-Glucocerebrosidase (D) Arylsulphatase A.
Description : Ceramidase is deficient in (A) Fabry’s disease (B) Farber’s disease (C) Krabbe’s disease (D) Tay-Sachs disease
Description : α-Galactosidase enzyme is defective in (A) Tay-sach’s disease (B) Refsum’s disease (C) Sandhoff’s disease (D) Fabry’s disease
Last Answer : Answer : D
Description : Gaucher’s disease is due to deficiency of the enzyme: (A) Sphingomyelinase (B) Glucocerebrosidase (C) Galactocerbrosidase (D) β-Galactosidase
Description : The enzyme deficient in metachromatic leukodystrophy is (A) Arylsulphatase A (B) Hexosaminidase A (C) Ceramidase (D) Sphingomyelinase
Description : Hexosaminidase A is deficient in (A) Tay-Sachs disease (B) Gaucher’s disease (C) Niemann-Pick disease (D) Fabry’s disease
Description : Which enzyme will be produced in a cell if there is a nonsense mutation in the lac Y gene? (a) Transacetylase (b) Lactose permease and transacetylase (c) β-galactosidase (d) Lactose permease
Last Answer : β-galactosidase
Description : Neimann-Pick disease is due to the deficiency of the enzyme: (A) Hexosaminidase A and B (B) Ceramidase (C) Ceramide lactosidase (D) Sphingomyelinase CHAPTER 6 CHAPTER 6 ENZYMES
Description : FAD containing enzyme, catalyzing formation of α, β unsaturated fatty acyl CoA derivative. (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thiolase
Description : The enzyme ceramidase is deficient in (A) Farber’s disease (B) Fabry’s disease (C) Sandhoff’s disease(D) Refsum’s disease
Description : .Gene regulation governing lactose operon of E.coli that involves the lac I gene product is (a) negative and repressible because repressor protein prevents transcription (b) feedback inhibition ... be induced by lactose (d) negative and inducible because repressor protein prevents transcription.
Last Answer : (d) negative and inducible because repressor protein prevents transcription.
Description : Lac operon’ in E. coli, is induced by (a) ‘I’ gene (b) promoter gene (c) β-galactosidase (d) lactose.
Last Answer : (c) β-galactosidase
Description : Gene regulation governing lactose operon of E.coli that involves the lac I gene product is (a) negative and repressible because repressor protein prevents transcription (b) feedback inhibition ... be induced by lactose (d) negative and inducible because repressor protein prevents transcription.
Description : Isoxsuprine increases limb blood flow in normal individuals, but is of limited efficacy in Buerger's disease, because in this disease: A. Vasodilator β adrenoceptors are deficient B. There is loss ... affected limb is reduced by organic obstruction D. The drug is not delivered to the affected site
Last Answer : C. Blood flow to the affected limb is reduced by organic obstruction
Description : Niemann-Pick disease results from deficiency of (A) Ceramidase (B) Sphingomyelinase (C) Arylsulphatase A (D) Hexosaminidase A
Description : Tay-Sachs disease results from inherited deficiency of (A) Arylsulphatase A (B) Hexosaminidase A (C) Sphingomyelinase (D) Ceramidase
Description : Gaucher's Disease is associated with the deficiency of : 1) Hexosaminidase A 2) Sphingomyelinase 3) Arylsulphatase-A 4) B- Glucosidase 5) Iduronidase
Last Answer : Answers-4 Hexosaminidase A deficiency is associated Tay-Sachs disease. Sphingomyelinase deficiency is associated with Niemann-Pick disease. Arylsulphatase-A deficiency is associated with metachromic leucodystrophy.Iduronidase deficiency is associated with Hurlers syndrome.
Description : Sildenafil is contraindicated in patients taking the following class of drugs: A. α-adrenergic blockers B. β-adrenergic blockers C. Organic nitrates D. Angiotensin converting enzyme inhibitors
Last Answer : C. Organic nitrates
Description : Refsum’s disease is due to deficiency of the enzyme: (A) Pytantate-α-oxidase (B) Glucocerebrosidase (C) Galactocerebrosidase (D) Ceramide trihexosidase
Description : An inborn error, maple syrup urine disease is due to deficiency of the enzyme: (A) Isovaleryl-CoAhydrogenase (B) Phenylalnine hydroxylase (C) Adenosyl transferase (D) α-Ketoacid decarboxylase
Description : The colonies of recombinant bacteria appear white in contrast to blue colonies of non-recombinant bacteria because of (a) insertional inactivation of alpha galactosidase in recombinant ... beta galactosidase (d) insertional inactivation of alpha galactosidase in non-recombinant bacteria.
Last Answer : (c) non-recombinant bacteria containing beta galactosidase
Description : Synthesis of RNA molecule is terminated by a signal which is recognised by (A) α-factor (B) β-factor (C) δ-factor (D) ρ
Description : Catabolism of thymidylate gives (A) α-alanine (B) β-alanine (C) α-aminoisobutyrate (D) β-aminoisobutyrate
Description : The mammalian DNA polymerase involved in error correction is (A) DNA polymerase α (B) DNA polymerase β (C) DNA polymerase γ (D) DNA polymerase δ
Description : Primase activity is present in (A) DNA polymerase II (B) DNA polymerase α (C) DNA polymerase β (D) DNA polymerase δ
Description : Replication of nuclear DNA in mammals is catalysed by (A) DNA polymerase α (B) DNA polymerase β (C) DNA polymerase γ (D) DNA polymerase III
Description : The key substance in the synthesis of purine, phosphoribosyl pyrophosphate is formed by (A) α-D-ribose 5-phosphate (B) 5-phospho β-D-ribosylamine (C) D-ribose (D) Deoxyribose
Description : The immediate parent of α, β and γ endorphins is (A) Pro-opiomelanocortin (B) β-lipotropin (C) ATCH (D) Lipoprotein
Description : Corticotropin releasing hormone controls the direct release of (A) Pro-opiomelanocortin (B) α MSH (C) β MSH (D) Endorphins
Description : Alloxan can experimentally induce diabetes mellitus due to (A) Stimulation of α cells of the islets of langerhans (B) Necrosis of the β cells of the islets (C) Potentiation of insulinase activity (D) Epinephrine like action
Description : Norepinephrine binds mainly to (A) α-Adrenergic receptors (B) β-Adrenergic receptrors (C) Muscarinic receptors (D) Nicotinic receptors
Description : Insulin receptor is made up of (A) One α-and one β-subunit (B) Two α-and two β-subunit (C) Two, α two β-and two γ-subunit (D) One α, one β-one γ-and one δ-subunit
Description : In the insulin receptor, tyrosine kinase domain is present in (A) α-Subunits (B) β-Subunits (C) γ-Subunits (D) δ-Subunits
Description : Insulin binding sites are present on the (A) α-subunits of insulin receptor (B) β-subunits of insulin receptor (C) γ-subunits of insulin receptor (D) α-and β−subunits of insulin receptor
Description : All the following statements about TSH are true except (A) It is a glycoprotein (B) It is made up of α- and β-subunits (C) Receptor recognition involves both the subunits (D) Its subunit is identical with those of FSH and LH
Description : All of the following can be formed from pro-opiomelanocortin except (A) α-and β-MSH (B) β-and γ-Lipotropins (C) α-and β-Endorphins(D) FSH
Description : Tyrosine kinase activity is present in (A) α-Adrenergic receptors (B) β-Adrenergic receptors (C) Cholinergic receptors (D) Insulin receptors
Description : The nucleotide binding site of G-proteins is present on their (A) α-Subunit (B) β-Subunit α- and β- (C) γ-Subunit (D) δ-Subunit
Description : Thyroid stimulating hormone is a dimer. The α-subunits of TSH, LH, FSH are identical. Thus the biological specificity must therefore be β subunit in which the number of amino acids is (A) 78 (B) 112 (C) 130 (D) 199
Description : Variable regions are present in (A) Immunoglobulins (B) α-Chains of T cell receptors (C) β-Chains of T cell receptors (D) All of these
Description : In the biosynthesis of the iron protoporphyrin, the product of the condensation between succinyl-CoA and glycine is (A) α-Amino β-ketoadipic acid (B) δ-Aminolevulinate (C) Hydroxymethylbilane (D) Uroporphyrinogen I