Description : The example of generation of a high energy phosphate at the substrate level in the citric acid cycle is the reaction: (A) Isocitrate α-Ketoglutarate (B) Succinate α-fumarate (C) Malate α-oxaloacetate (D) Succinyl CoA α-Succinate
Last Answer : Answer : D
Description : The reaction of Kreb’s cycle which does not require cofactor of vitamin B group is (A) Citrate isocitrate (B) α -Ketoglutarate succinate (C) Malate oxaloacetate (D) Succinate fumarate
Last Answer : Answer : A
Description : Fluoroacetate inhibits the reaction of citric acid cycle: (A) Isocitrate α-Ketoglutarate (B) Fumarate α-Malate (C) Citrate α-cis-aconitate (D) Succinate α-fumarate
Last Answer : Answer : C
Description : All of the following are intermediates of citric acid cycle except (A) Oxalosuccinate (B) Oxaloacetate (C) Pyruvate (D) Fumarate
Description : The substance which may be considered to play a catalytic role in citric acid cycle is (A) Oxaloacetate (B) Isocitrate (C) Malate (D) Fumarate
Description : The carrier of the citric acid cycle is (A) Succinate (B) Fumarate (C) Malate (D) Oxaloacetate
Last Answer : D
Description : An enzyme of the citric acid cycle also found outside the mitochondria is (A) Isocitrate dehydrogenase (B) Citrate synthetase (C) α-Ketoglutarate dehydrogenase (D) Malate dehydrogenase
Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase
Last Answer : Answer : B
Description : All of the following compounds are intermediates of TCA cycle except (A) Maleate (B) Pyruvate (C) Oxaloacetate (D) Fumarate
Description : Out of 24 mols of ATP formed in TCA cycle, 2 molecules of ATP can be formed at “substrate level” by which of the following reaction ? (A) Citric acid→ Isocitric acid (B) Isocitrate→ Oxaloacetate (C) Succinic acid→ Fumarate (D) Succinylcat→ Succinic acid
Description : A compound serving a link between citric acid cycle and urea cycle is (A) Malate (B) Citrate (C) Succinate (D) Fumarate
Description : A competitive inhibitor of succinic dehydrogenase is (a) α-ketoglutarate (b) malate (c) malonate (d) oxaloacetate.
Last Answer : (c) malonate
Description : A carrier molecule in the citric acid cycle is (A) Acetyl-CoA (B) Citrate (C) Oxaloacetate (D) Malate
Description : Mitochondrial membrane is freely preamble to (A) Pyruvate (B) Malate (C) Oxaloacetate (D) Fumarate
Description : The reaction catalysed by α-ketoglutarate dehydrogenase in the citric acid cycle requires (A) NAD (B) NADP (C) ADP (D) ATP
Description : Malonate is an inhibitor of (A) Malate dehydrogenase (B) α-Ketoglutarate dehydrogenase (C) Succinate dehydrogenase (D) Isocitrate dehydrogenase
Description : The integrator between the TCA cycle and urea cycle is (A) Fumarate (B) Malate (C) Pyruvate (D) Citrate
Description : If all the enzymes, intermediates and cofactors of the citric acid cycle as well as an excess of the starting substrate acetylCoA are present and functional in an organelle free solution at the appropriate ... oxygen (B) Half life of enzyme (C) Turnover of intermediates (D) Reduction of cofactors
Description : The enzyme -ketoglutarate dehydrogenase in the citric acid cycle requires (A) Lipoate (B) Folate (C) Pyridoxine (D) Inositol
Description : Among citric acid cycle enzymes, a flavoprotein is (A) Malate (B) Fumarase (C) Succinate dehrogenase (D) Isocitrate dehrogenase
Description : The rate of citric acid cycle is controlled by the allosteric enzyme: (A) Aconitase (B) Fumarase (C) Fumarase (D) Malate dehydrogenase
Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate
Last Answer : A
Description : Active transport of sugar is depressed by the agent: (A) Oxaloacetate (B) Fumarate (C) Malonate (D) Succinate
Last Answer : C
Description : All α-amino acids have one asymmetric carbon atom except (A) Arginine (B) Glycine (C) Aspartic acid (D) Histidine
Description : Fully activated pyruvate carboxylase depends upon the presence of (A) Malate and Niacin (B) Acetyl CoA and biotin (C) Acetyl CoA and thiamine pyrophosphate (D) Oxaloacetate and biotin
Description : The metabolism of protein is integrated with that of carbohydrate and fat through (A) Oxaloacetate (B) Citrate (C) Isocitrate (D) Malate
Description : Mitochondrial α-ketoglutarate dehydrogenase complex requires all the following to function except (A) CoA (B) FAD (C) NAD+ (D) NADP+
Description : All of the following are required for synthesis of alanine except (A) Pyruvate (B) α-ketoglutarate (C) Glutamate (D) Pyridoxal phosphate
Description : In TCA cycle, oxalosuccinate is converted to α-ketoglutarate by the enzyme: (A) Fumarase (B) Isocitrate dehydrogenase (C) Aconitase (D) Succinase
Description : In Krebs’ cycle, the FAD precipitates as electron acceptor during the conversion of (a) fumaric acid to malic acid (b) succinic acid to fumaric acid (c) succinyl CoA to succinic acid (d) α-ketoglutarate to succinyl CoA.
Last Answer : (b) succinic acid to fumaric acid
Description : Carbon skeleton produced during respiration. (Eg. `alpha`-ketoglutarate, OAA etc. intermediates) are used as precursor for biosynthesis of other molec
Last Answer : Carbon skeleton produced during respiration. (Eg. `alpha`-ketoglutarate, OAA etc. intermediates) are ... biosynthesis of other molecules in the cell.
Description : The α-carbon of all the amino acids is a chirality center except for __________. (a) Glycine (b) Threonine (c) Proline (d) Aspartic acid
Last Answer : Glycine
Description : Lipoic acid is a conenzyme for (A) Pyruvate dehydrogenase (B) α-Ketoglutarate dehydrogenae (C) Both (A) and (B) (D) None of these
Description : Pyruvate dehydrogenase complex and α-ketoglutarate dehydrogenase complex require the following for their oxidative decarboxylation: (A) COASH and Lipoic acid (B) NAD+ and FAD (C) COASH and TPP (D) COASH, TPP,NAD+,FAD, Lipoate
Description : The following 4 amino acids are required for completion of urea cycle except (A) Aspartic acid (B) Arginine (C) Ornithine (D) Glycine
Description : Commercial scale production of amino acids is typically carried out using A- regulatory mutants to cause overproduction of biochemical intermediates B- creation of an intentional increase in membrane permeability to increase release of the amino acids C- both (a) and (b) D- none of the above
Last Answer : both (a) and (b)
Description : NAD is required as a conenzyme in (A) Citric acid cycle (B) HMP shunt (C) β-Oxidation of fatty acids (D) Both (A) and (C)
Description : An important reaction for the synthesis of amino acid from carbohydrate intermediates is transamination which requires the cofactor: (A) Thiamin (B) Riboflavin (C) Niacin (D) Pyridoxal phosphat
Description : Oxidative degradation of acetyl CoA in the citric acid cycle gives a net yield of all the following except (A) FADH2 (B) 3 NADH (C) 2 ATP (D) 2CO2
Description : Isocitrate dehydrogenase is allosterically inhibited by (A) Oxalosuccinate (B) α-Ketoglutarate (C) ATP (D) NADH
Description : The hexose monophosphate pathway includes the enzyme: (A) Maltase dehydrogenase (B) Hexokinase (C) α-Ketoglutarate dehydrogenase (D) Glucose-6-phosphate dehydrogenase
Description : Formation of succinyl-CoA from α-Ketoglutarate is inhibited by (A) Fluoroacetate (B) Arsenite (C) Fluoride (D) Iodoacetate
Description : An important finding in Histidinemia is (A) Impairment of conversion of α-Glutamate to α-ketoglutarate (B) Speech defect (C) Decreased urinary histidine level (D) Patients can not be treated by diet
Description : Alanine can be synthesized from (A) Glutamate and α-ketoglutarate (B) Pyruvate and glutamate (C) Pyruvate and α-ketoglutarate (D) Asparate and α-ketoglutarate
Description : Which one of the following compounds cannot give rise to the net synthesis of Glucose? (A) Lactate (B) Glycerol (C) α-ketoglutarate (D) Acetyl CoA
Last Answer : B
Description : An enzyme in saliva which hydrolyzes starch is (A) Pepsinogen (B) Chymotrysin (C) α-Amylase (D) Malate
Description : All the following are omega-6-fatty acids except (A) Linoleic acid (B) α-Linolenic acid (C) γ-Linolenic acid (D) Arachidonic acid
Description : Lactate formed in muscles can be utilised through (A) Rapoport-Luebeling cycle (B) Glucose-alanine cycle (C) Cori’s cycle (D) Citric acid cycle
Description : In the extra mitochondrial synthesis of fatty acids, CO2 is utilized (A) To keep the system anaerobic and prevent regeneration of acetyl CoA (B) In the conversion of malonyl to CoA hydroxybutyryl CoA (C ... of acetyl CoA to malonyl CoA (D) In the formation of acetyl CoA from 1 carbon intermediates