Description : The enzymes involved in Phosphorylation of glucose to glucose 6- phosphate are (A) Hexokinase (B) Glucokinase (C) Phosphofructokinase (D) Both (A) and (B)
Last Answer : D
Description : Glucose-6-phosphate is an allosteric inhibitor of (A) Glucokinase (B) Hexokinase (C) Phosphohexose isomerase (D) None of these
Last Answer : Answer : B
Description : At low blood glucose concentration, brain but not liver will take up glucose. It is due to the (A) Low Km of hexokinase (B) Low Km of glucokinase (C) Specificity of glucokinase (D) Blood brain barrier
Last Answer : Answer : A
Description : Conversion of glucose to glucose-6- phosphate in human liver is by (A) Hexokinase only (B) Glucokinase only (C) Hexokinase and glucokinase (D) Glucose-6-phosphate dehydrogenase
Last Answer : C
Description : Hexokinase has a high affinity for glucose than (A) Fructokinase (B) Galactokinase (C) Glucokinase (D) All of the above
Description : Insulin decreases the synthesis of (A) Hexokinase (B) Glucokinase (C) PEP carboxykinase (D) Glycogen synthetase
Last Answer : Answer : C
Description : ATP is a co-substrate as well as an allosteric inhibitor of (A) Phosphofructokinase (B) Hexokinase (C) Glucokinase (D) None of these
Description : Glucose 6-phosphate is converted to glucose 1-phosphate in a reaction catalysed by the enzyme phosphoglucomutase, which is (A) Phosphorylated (B) Dephosphorylated (C) Phosphorylated-dephosphorylated (D) Phosphorylated-dephosphorylatedrephosphorylated
Last Answer : Answer : D
Description : One of the following statement is correct: (A) Glycogen synthase ‘a’ is the phosphorylated (B) cAMP converts glycogen synthase b to ‘a’ (C) Insulin converts glycogen synthase b to a (D) UDP glucose molecules interact and grow into a Glycogen tree
Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase
Description : Glucokinase (A) Is widely distributed and occurs in most mammalian tissues (B) Has a high km for glucose and hence is important in the phosphorylation of glucose primarily after ingestion of a carbohydrate rich meal (C) Is widely distributed in Prokaryotes (D) None of these
Last Answer : B
Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Description : Hexokinase (Glucose + ATP → Glucose-6– P + ADP) belongs to the category: (A) Transferases (B) Lysases (C) Oxidoreductases (D) Isomerases
Description : The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase
Description : The hexose monophosphate pathway includes the enzyme: (A) Maltase dehydrogenase (B) Hexokinase (C) α-Ketoglutarate dehydrogenase (D) Glucose-6-phosphate dehydrogenase
Description : Hexokinase is inhibited in an allosteric manner by (A) Glucose-6-Phosphate (B) Glucose-1-Phosphate (C) Fructose-6-phosphate (D) Fructose-1, 6-biphosphate
Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency
Description : Which of the following is not an enzyme involved in glycolysis? (A) Euolase (B) Aldolose (C) Hexokinase (D) Glucose oxidase
Description : Which one of the following biomolecules is correctly characterized? (a) Lecithin-a phosphorylated glyceride found in cell membrane. (b) Palmitic acid - an unsaturated fatty acid with 18 carbon atoms. ... Alanine amino acid - contains an amino group and an acidic group anywhere in the molecule.
Last Answer : (a) Lecithin-a phosphorylated glyceride found in cell membrane
Description : An 16-year-old man presents with polyuria and polydipsia. Which of the following may confirm the diagnosis of diabetes mellitus? 1) A random plasma glucose of >7.5 mmol/L 2) A finding of 3+ ketonuria 3) An HbA1c of 7.0% 4) A fasting plasma glucose of 7.5 mmol/L 5) An abnormal glucose tolerance test
Last Answer : Answers-4 The diagnosis is usually relatively easy to confirm in a symptomatic subject. A random glucose of >11.1 mmol/L or a fasting glucose of >7.0 mmol/L would be regarded as ... haemoglobin (HbA1c) is also highly suggestive but not diagnostic. A glucose tolerance test is rarely needed.
Description : Both Acyl carrier protein (ACP) of fatty acid synthetase and coenzyme (CoA) are (A) Contain reactive phosphorylated (B) Contain thymidine (C) Contain phosphopantetheine reactive groups (D) Contain cystine reactive groups
Description : Synthesis of the following enzymes is increased during starvation. (A) Digestive enzymes (B) Gluconeogenic enzymes (C) Urea cycle enzymes (D) Glucokinase
Description : An example of competitive inhibition of an enzyme is the inhibition of a. Succinic dehydrogenase by malonic acid b. Cytochrome oxidase by cyanide c. Hexokinase by glucose-6-phosphate d. Carbonic anhydrase by carbon dioxide
Last Answer : Ans: A
Description : Conversion of glucose to glucose-6-phosphate, the first irreversible reaction of glycolysis, is catalysed by (a) phosphofructokinase (b) aldolase (c) hexokinase (d) enolase.
Last Answer : (c) hexokinase
Description : Phosphorylated IRS-1 activates GRB-2 which is (A) G-protein receptor binding protein-2 (B) Growth factor receptor binding protein-2 (C) Growth hormone receptor binding protein-2 (D) Glucocorticoid receptor binding protein-2 226 MCQs IN BIOCHEMISTRY
Description : The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor
Description : In citric acid cycle, GDP is phosphorylated by (A) Succinate dehydrogenase (B) Aconitase (C) Succinate thiokinase (D) Fumarse
Description : All the following vitamins give rise to cofactors that are phosphorylated in the active form except (A) Vitamin A (B) Vitamin B1 (C) Vitamin D (D) Vitamin E
Description : Galactose is phosphorylated by galactokinase to form (A) Galactose-6-phosphate (B) Galactose-1, 6 diphosphate (C) Galactose-1-phosphate (D) All of these
Description : A gluconeogenic enzyme among the following is (A) Phosphofructokinase (B) Pyruvate kinase (C) Phosphoenol pyruvate carboxykinase (D) Glucokinase
Description : Glucokinase is found in (A) Muscles (B) Brain (C) Liver (D) All of these
Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency
Description : What is glucokinase?
Last Answer : The reaction is similar to hexokinase. But glucokinase is present only in liver, acts specifically on glucose, and is active when glucose level in blood is increased after a food.
Description : The fasting blood glucose level in adults in mg/100 ml is – (1) 200 (2) 160 (3) 100 (4) 60
Last Answer : (3) 100 Explanation: The normal range of concentration of fasting blood sugar is 80 to 120 mg/ml; in the testing of true blood sugar, the normal range of concentration is 70 to 100 ... normal glucose levels fall between 70 and 150 mg. Higher levels may indicate diseases such as diabetes mellitus.
Description : A person is undergoing prolonged fasting. His urine will be found to contain abnormal quantities of (a) fats (b) amino acids (c) glucose (d) ketones.
Last Answer : d) ketones.
Description : The fasting blood glucose level in adults in mg/100 ml is (1) 200 (2) 160 (3) 100 (4) 60
Last Answer : 100
Description : The enzymes present in the membrane of mitochondria are (A) Flavoproteins and cytochromes (B) Fumarase and lipase (C) Enolase and catalase (D) Hexokinase and zymase
Description : An example of feedback inhibition is (A) Allosteric inhibition of hexokinase by glucose6-phosphate (B) Cyanide action on cytochrome (C) Sulpha drug on folic acid synthesizer bacteria (D) Reaction between succinic dehydrogenase and succinic acid
Description : Fructose 2, 3 bi phosphate is a powerful allosteric activator of (A) Fructose 1, 6 diphosphatase (B) Phosphofructokinase (C) Hexokinase (D) Fructokinase
Description : The enzyme hexokinase is a (A) Hydrolase (B) Oxidoreductase (C) Transferase (D) Ligase
Description : Which of the following is a substratespecific enzyme? (A) Hexokinase (B) Thiokinase (C) Lactase (D) Aminopeptidase
Description : Conversion of fructose to sorbitol is catalysed by the enzyme: (A) Sorbitol dehydrogenase (B) Aldose reductase (C) Fructokinase (D) Hexokinase
Description : An enzyme involved in gluconeogenesis is (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Hexokinase (D) Phosphohexose isomerase
Description : The enzyme of the glycolic pathway, sensitive to inhibiton by fluoride ions is (A) Hexokinase (B) Aldolase (C) Enolase (D) Pyruvate kinase
Description : Example of an extracellular enzyme is (A) Lactate dehydrogenase (B) Cytochrome oxidase (C) Pancreatic lipase (D) Hexokinase
Description : The glycolysis is regulated by (A) Hexokinase (B) Phosphofructokinase (C) Pyruvate kinase (D) All of these
Description : Which one of the following is a rate limiting enzyme of gluconeogenesis? (A) Hexokinase (B) Phsophofructokinase (C) Pyruvate carboxylase (D) Pyruvate kinase
Description : What is hexokinase?
Last Answer : Hexokinase is the first step in the glycolysis pathway. It phosphorylates glucose to glucose-6-phosphate.
Description : Plasma becomes milky (A) Due to high level of HDL (B) Due to high level of LDL (C) During fasting (D) After a meal
Description : Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function