Description : The reaction catalysed by phosphofructokinase (A) Is activated by high concentrations of ATP and citrate (B) Uses fruitose-1-phosphate as substrate (C) Is the rate-limiting reaction of the glycolytic pathway (D) Is inhibited by fructose 2, 6-bisphosphate
Last Answer : C
Description : Fructose-2, 6-biphosphate is formed by the action of (A) Phosphofructokinase-1 (B) Phosphofructokinase-2 (C) Fructose biphosphate isomerase (D) Fructose-1, 6-biphosphatase
Last Answer : B
Description : Hexokinase is inhibited in an allosteric manner by (A) Glucose-6-Phosphate (B) Glucose-1-Phosphate (C) Fructose-6-phosphate (D) Fructose-1, 6-biphosphate
Last Answer : Answer : A
Description : Phosphofructokinase key enzyme in glycolysis is inhibited by (A) Citrate and ATP (B) AMP (C) ADP (D) TMP
Description : The following are true about the oxidation of glucose: a. glycolysis produces 3% of the energy ultimately obtained from glucose b. the first stage of glycolysis involves phosphorylation of glucose to 1,6-fructose biphosphate. c. glucose enters the Kreb's cycle as pyruvate d. all above
Last Answer : all above
Description : Anion gap of plasma can be due to the presence of all the following except (A) Bicarbonate (B) Lactate (C) Pyruvate (D) Citrate
Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate
Last Answer : A
Description : A reaction which may be considered an isomerisation is (A) Glucose 6-Phosphate fructose 6 phosphate (B) 3-Phosphoglycerate 2-phosphoglycerate (C) 2-phosphoglycerate phosphoenolpyruvate (D) Pyruvate Lactate
Description : Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate
Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte
Description : PRPP synthetase is allosterically inhibited by (A) AMP (B) ADP (C) GMP (D) All of these
Last Answer : Answer : D
Description : Isocitrate dehydrogenase is allosterically inhibited by (A) Oxalosuccinate (B) α-Ketoglutarate (C) ATP (D) NADH
Last Answer : Answer : C
Description : In the figures shown below, fructose 1,6- biphosphate is located at point: (A) A (B) B (C) C (D) D
Description : Which of the following is an allosteric enzyme? (A) Phosphohexose isomerase (B) Phosphotriose isomerase (C) Lactate dehydrogenase (D) Phosphofructokinase
Description : Fructose 2, 3 bi phosphate is a powerful allosteric activator of (A) Fructose 1, 6 diphosphatase (B) Phosphofructokinase (C) Hexokinase (D) Fructokinase
Last Answer : Answer : B
Description : A gluconeogenic enzyme among the following is (A) Phosphofructokinase (B) Pyruvate kinase (C) Phosphoenol pyruvate carboxykinase (D) Glucokinase
Description : Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase
Description : In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase
Description : The glycolysis is regulated by (A) Hexokinase (B) Phosphofructokinase (C) Pyruvate kinase (D) All of these
Last Answer : D
Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate
Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate
Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate
Description : How many ATPs are produced in the conversion of phosphoenol pyruvate to citrate? (A) 1 (B) 2 (C) 4 (D) 6
Description : All the following statements about acetyl CoA carboxylase are true except: (A) It is activated by citrate (B) It is inhibited by palmitoyl CoA (C) It can undergo covalent modification (D) Its dephosphorylated form is inactive
Description : In sugarcane plant 14CO2 is fixed to malic acid, in which the enzyme that fixes CO2 is (a) ribulose biphosphate carboxylase (b) phosphoenol pyruvic acid carboxylase (c) ribulose phosphate kinase (d) fructose phosphatase.
Last Answer : (b) phosphoenol pyruvic acid carboxylase
Description : Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase
Description : End product of aerobic glycolysis is (A) Acetyl CoA (B) Lactate (C) Pyruvate (D) CO2 and H2O
Description : Which of the following intermediates of metabolism can be both a precursor and a product of glucose? (A) Lactate (B) Pyruvate (C) Alanine (D) Acetyl-CoA
Description : Pyruvate dehydrogenase a multienzyme complex is required for the production of (A) Acetyl-CoA (B) Lactate (C) Phosphoenolpyruvate (D) Enolpyruvate
Description : Erythrocytes under normal conditions and microorganisms under anaerobic conditions may accumulate (A) NADPH (B) Pyruvate (C) Phosphoenolpyruvate (D) Lactate
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Description : Compared to the resting state, vigorously contracting muscle shows (A) An increased conversion of pyruvate to lactate (B) Decreased oxidation of pyruvate of CO2 and water (C) A decreased NADH/NAD+ ratio (D) Decreased concentration of AMP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 21
Description : When O2 supply is inadequate, pyruvate is converted to (A) Phosphopyruvate (B) Acetyl CoA (C) Lactate (D) Alanine
Description : Cori’s cycle transfers (A) Glucose from muscles to liver (B) Lactate from muscles to liver (C) Lactate from liver to muscles (D) Pyruvate from liver to muscles
Description : In which condition pyruvate is produced, and when lactate?
Last Answer : In aerobic condition pyruvate is produced. When oxygen is lacking, lactate is produced.
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate
Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : While citrate is converted to isocitrate in the mitochondria, it is converted to _______ in the cytosol. (A) Acetyl CoA + oxaloacetate (B) Acetyl CoA + malonyl CoA (C) Acetyl CoA + Pyruvate (D) Acetyl CoA + acetoacetyl CoA
Description : The integrator between the TCA cycle and urea cycle is (A) Fumarate (B) Malate (C) Pyruvate (D) Citrate
Description : An aneplerotic reaction which sustains the availability of oxaloacetate is the carboxylation of (A) Glutamate (B) Pyruvate (C) Citrate (D) Succinate
Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase
Description : Insulin increases the activity of (A) Pyruvate kinase (B) Phosphorylase (C) Triacylglycerol kinase (D) Fructose 2, 6-bisphosphatase
Description : Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6-biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase (D) Stimulation of synthesis of eltroxykinase
Description : Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible: (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1, 6 diphosphate to ... phosphate (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Description : Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible. (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1,6-bisphosphate to fructose- ... (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : Pyruvate dehydrogenase activity is inhibited by (A) Mercury (B) Zinc (C) Calcium (D) Sodium