‘Clearing factor’ is (A) Lipoprotein lipase (B) Crotonase (C) 7-dehydro cholesterol (D) β-sitosterol

‘Clearing factor’ is (A) Lipoprotein lipase (B) Crotonase (C) 7-dehydro cholesterol (D) β-sitosterol
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This interferes with cholesterol absorption (A) Lipoprotein lipase (B) Creatinase (C) 7-dehydrocholesterol (D) β-sitosterol

Description : This interferes with cholesterol absorption (A) Lipoprotein lipase (B) Creatinase (C) 7-dehydrocholesterol (D) β-sitosterol

Last Answer : Answer : D

The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level

Description : The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level

Last Answer : C. It increases the incidence of myopathy due to statins

An important zinc containing enzyme is (A) Carboxypeptidase A (B) Isocitrate dehydrogenase (C) Cholinesterate (D) Lipoprotein lipase

Description : An important zinc containing enzyme is (A) Carboxypeptidase A (B) Isocitrate dehydrogenase (C) Cholinesterate (D) Lipoprotein lipase

Last Answer : Answer : A

The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase

Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase

Last Answer : Answer : A

A non-functional plasma enzyme is (A) Psudocholinesterase (B) Lipoprotein lipase (C) Proenzyme of blood coagulation (D) Lipase

Description : A non-functional plasma enzyme is (A) Psudocholinesterase (B) Lipoprotein lipase (C) Proenzyme of blood coagulation (D) Lipase

Last Answer : Answer : D

An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase

Description : An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase

Last Answer : Answer : A

Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipase A2 (D) Lipoprotein lipase

Description : Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipase A2 (D) Lipoprotein lipase

Last Answer : Answer : B

The triacyl glycerol present in plasma lipoproteins are hydrolyzed by (A) Linqual lipase (B) Pancreatic lipase (C) Colipase (D) Lipoprotein lipase

Description : The triacyl glycerol present in plasma lipoproteins are hydrolyzed by (A) Linqual lipase (B) Pancreatic lipase (C) Colipase (D) Lipoprotein lipase

Last Answer : Answer : D

Genetic deficiency of lipoprotein lipase causes hyperlipoproteinaemia of following type: (A) Type I (B) Type IIa (C) Type IIb (D) Type V

Description : Genetic deficiency of lipoprotein lipase causes hyperlipoproteinaemia of following type: (A) Type I (B) Type IIa (C) Type IIb (D) Type V

Last Answer : Answer : A

Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase

Description : Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase

Last Answer : Answer : C

Lipoprotein lipase deficiency is associated with: 1) Abetalipoproteinaemia 2) Combined hyperlipidaemia 3) Familial combined hyperlipidaemia 4) Familial Hypercholesterolaemia 5) Marked Hypertriglyceridaemia

Description : Lipoprotein lipase deficiency is associated with: 1) Abetalipoproteinaemia 2) Combined hyperlipidaemia 3) Familial combined hyperlipidaemia 4) Familial Hypercholesterolaemia 5) Marked Hypertriglyceridaemia

Last Answer : Answers-5 Lipoprotein lipase deficiency is autosomal recessive and associated with increased chylomicrons and marked hypertriglyceridaemia.

The immediate parent of α, β and γ endorphins is (A) Pro-opiomelanocortin (B) β-lipotropin (C) ATCH (D) Lipoprotein

Description : The immediate parent of α, β and γ endorphins is (A) Pro-opiomelanocortin (B) β-lipotropin (C) ATCH (D) Lipoprotein

Last Answer : Answer : B

The compound which has the lowest density is (A) Chylomicron (B) β-Lipoprotein (C) α-Lipoprotein (D) pre β-Lipoprotein

Description : The compound which has the lowest density is (A) Chylomicron (B) β-Lipoprotein (C) α-Lipoprotein (D) pre β-Lipoprotein

Last Answer : Answer : A

The β-lipoprotein fraction increases in severe (A) Diabetes Mellitus (B) Uremia (C) Nephritis (D) Muscular dystrophy

Description : The β-lipoprotein fraction increases in severe (A) Diabetes Mellitus (B) Uremia (C) Nephritis (D) Muscular dystrophy

Last Answer : Answer : A

Free fatty acids are transported in the blood (A) Combined with albumin (B) Combined with fatty acid binding protein (C) Combined with β -lipoprotein (D) In unbound free salts

Description : Free fatty acids are transported in the blood (A) Combined with albumin (B) Combined with fatty acid binding protein (C) Combined with β -lipoprotein (D) In unbound free salts

Last Answer : Answer : A

Which of the following is a dipeptide? (A) Anserine (B) Glutathione (C) Glucagon (D) β -Lipoprotein

Description : Which of the following is a dipeptide? (A) Anserine (B) Glutathione (C) Glucagon (D) β -Lipoprotein

Last Answer : Answer : A

A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the following? a. Increased glucose uptake and increased glycogen breakdown occur in this circumstance. b. Suppressed activity of lipoprotein lipase results from TNFa c. TNFa stimulates lipolysis d. The differentiation process of pre-adipocytes is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs

Description : A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the ... is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs

Last Answer : Answer: a, b, c, d, e Tumor cachexia appears to be mediated by TNFa. Lipopolysaccharide (LPS), as well as other cytokines, activate a variety of inflammatory cells, most ... chronic syndromes of anorexia, weight loss, and cachexia that are associated with both chronic infection and malignancy

Choose the correct statement(s) about actions of insulin: A. It favours translocation of glucose transporters from intracellular site to the plasma membrane B. It enhances transcription of lipoprotein lipase in vascular endothelium C. It increases production of the enzyme glucokinase D. All of the above

Description : Choose the correct statement(s) about actions of insulin: A. It favours translocation of glucose transporters from intracellular site to the plasma membrane B. It enhances transcription of lipoprotein ... vascular endothelium C. It increases production of the enzyme glucokinase D. All of the above

Last Answer : D. All of the above

The major source of extracellular cholesterol for human tissue is (A) Very low density lipoprotein (B) High density lipoprotein (C) Low density lipoprotein (D) Albumin

Description : The major source of extracellular cholesterol for human tissue is (A) Very low density lipoprotein (B) High density lipoprotein (C) Low density lipoprotein (D) Albumin

Last Answer : Answer : C

This lipoprotein removes cholesterol from the body (A) HDL (B) VLDL (C) IDL (D) Chylomicrons

Description : This lipoprotein removes cholesterol from the body (A) HDL (B) VLDL (C) IDL (D) Chylomicrons

Last Answer : Answer : A

The lipoprotein richest in cholesterol is (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Description : The lipoprotein richest in cholesterol is (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Last Answer : Answer : C

With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the formation of red blood cell membranes. 3) Chylomicrons are synthesized in the liver. 4) HDL is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.

With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the formation of red blood cell membranes. 3) Chylomicrons are synthesized in the liver. 4) HDL is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.

Maximum cholesterol content is in which lipoprotein?

Description : Maximum cholesterol content is in which lipoprotein?

Last Answer : LDL (Beta lipoprotein). 

In abetalipoproteinemia, the biochemical defect is in (A) Apo-B synthesis (B) Lipprotein lipase activity (C) Cholesterol ester hydrolase (D) LCAT activity

Description : In abetalipoproteinemia, the biochemical defect is in (A) Apo-B synthesis (B) Lipprotein lipase activity (C) Cholesterol ester hydrolase (D) LCAT activity

Last Answer : Answer : A

The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to (A) CO2 and water (B) Cholesterol (C) Fatty acids (D) Ketone bodies

Description : The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to (A) CO2 and water (B) Cholesterol (C) Fatty acids (D) Ketone bodies

Last Answer : Answer : A

Which of the following is wrongly matched in the given table? Microbe Product Application (a) Streptococcus Streptokinase Removal of clot from blood vessel (b) Clostridium butylicum Lipase Removal of oil stains (c) Trichoderma polysporum Cyclosporin A Immuno- suppressive drug (d) Monascus purpureus Statins Lowering of blood cholesterol

Description : Which of the following is wrongly matched in the given table? Microbe Product Application (a) Streptococcus Streptokinase Removal of clot from blood vessel (b) Clostridium butylicum Lipase ... Cyclosporin A Immuno- suppressive drug (d) Monascus purpureus Statins Lowering of blood cholesterol

Last Answer : (b) Clostridium butylicum Lipase Removal of oil stains

Lipase can act only at pH: (A) 2.5–4 (B) 3.5–5 (C) 4 to 5 (D) 5–7

Description : Lipase can act only at pH: (A) 2.5–4 (B) 3.5–5 (C) 4 to 5 (D) 5–7

Last Answer : Answer : D

Synthesis of RNA molecule is terminated by a signal which is recognised by (A) α-factor (B) β-factor (C) δ-factor (D) ρ

Description : Synthesis of RNA molecule is terminated by a signal which is recognised by (A) α-factor (B) β-factor (C) δ-factor (D) ρ

Last Answer : Answer : D

After termination of the synthesis of RNA molecule, the core enzymes separate from the DNA template. The core enzymes then recognize a promoter at which the synthesis of a new RNA molecule commences, with the assistance of (A) Rho (ρ) factor (B) δ factor (C) β factor (D) σ factor

Description : After termination of the synthesis of RNA molecule, the core enzymes separate from the DNA template. The core enzymes then recognize a promoter at which the synthesis of a new RNA molecule commences, with the assistance of (A) Rho (ρ) factor (B) δ factor (C) β factor (D) σ factor

Last Answer : Answer : D

Correct ordering of lipoprotein molecules from lowest to the greater density is (A) LDL, IDL, VLDL, chylomicron (B) Chylomicron, VLDL, IDL, LDL (C) VLDL, IDL, LDL, chylomicron (D) LDL, VLDL, IDL, chylomicron

Description : Correct ordering of lipoprotein molecules from lowest to the greater density is (A) LDL, IDL, VLDL, chylomicron (B) Chylomicron, VLDL, IDL, LDL (C) VLDL, IDL, LDL, chylomicron (D) LDL, VLDL, IDL, chylomicron

Last Answer : Answer : B

The lipoprotein with the fastest electrophoretic mobility and lowest TG content are (A) VLDL (B) LDL (C) HDL (D) Chylomicrones

Description : The lipoprotein with the fastest electrophoretic mobility and lowest TG content are (A) VLDL (B) LDL (C) HDL (D) Chylomicrones

Last Answer : Answer : C

The first lipoprotein to be secreted by the liver is (A) VLDL (B) nascent VLDL (C) LDL (D) IDL

Description : The first lipoprotein to be secreted by the liver is (A) VLDL (B) nascent VLDL (C) LDL (D) IDL

Last Answer : Answer : B

The protein moiety of lipoprotein is known as (A) Apoprotein (B) Pre-protein (C) Post-protein (D) Pseudoprotein

Description : The protein moiety of lipoprotein is known as (A) Apoprotein (B) Pre-protein (C) Post-protein (D) Pseudoprotein

Last Answer : Answer : A

Lipoprotein present in cell membrane is by nature: (A) Hydrophilic (B) Hydrophobic (C) Both (A) and (B) (D) None of these

Description : Lipoprotein present in cell membrane is by nature: (A) Hydrophilic (B) Hydrophobic (C) Both (A) and (B) (D) None of these

Last Answer : Answer : A

Lecithins combine with protein to form (A) Phosphoprotein (B) Mucoprotein (C) Lipoprotein (D) Glycoprotein

Description : Lecithins combine with protein to form (A) Phosphoprotein (B) Mucoprotein (C) Lipoprotein (D) Glycoprotein

Last Answer : Answer : C

A lipoprotein inversely related to the incidence of coronary artherosclerosis is (A) VLDL (B) IDL (C) LDL (D) HDL

Description : A lipoprotein inversely related to the incidence of coronary artherosclerosis is (A) VLDL (B) IDL (C) LDL (D) HDL

Last Answer : Answer : D

A lipoprotein associated with high incidence of coronary atherosclerosis is (A) LDL (B) VLDL (C) IDL (D) HDL

Description : A lipoprotein associated with high incidence of coronary atherosclerosis is (A) LDL (B) VLDL (C) IDL (D) HDL

Last Answer : Answer : A

The apolipoprotein which acts as actiator of extrahepatic lipoprotein is (A) Apo-A (B) Apo-B (C) Apo-C (D) Apo-D

Description : The apolipoprotein which acts as actiator of extrahepatic lipoprotein is (A) Apo-A (B) Apo-B (C) Apo-C (D) Apo-D

Last Answer : Answer : C

The lipoprotein associated with activation of LCAT is (A) HDL (B) LDL (C) VLDL (D) IDL

Description : The lipoprotein associated with activation of LCAT is (A) HDL (B) LDL (C) VLDL (D) IDL

Last Answer : Answer : A

The lipoprotein with the fastest electrophoretic mobility and the lowest triglyceride content is (A) Chylomicron (B) VLDL (C) IDL (D) HDL

Description : The lipoprotein with the fastest electrophoretic mobility and the lowest triglyceride content is (A) Chylomicron (B) VLDL (C) IDL (D) HDL

Last Answer : Answer : D

Carbonic anhydrase is an example of (A) Lipoprotein (B) Phosphoprotein (C) Metalloprotein (D) Chromoprotein

Description : Carbonic anhydrase is an example of (A) Lipoprotein (B) Phosphoprotein (C) Metalloprotein (D) Chromoprotein

Last Answer : Answer : C

What is the normal level of lipoprotein (a) ?

Description : What is the normal level of lipoprotein (a) ?

Last Answer : In 40% population, there is no detectable level of Lp(a) in serum. In 20% of population, the Lp(a) concentration in blood is more than 30 mg/dl, and these persons are susceptible to heart attack at a younger age.

What is the significance of lipoprotein (a)?

Description : What is the significance of lipoprotein (a)? 

Last Answer : Lp(a) is associated with heart attacks at the age of 30 or 40 years. Indians have a higher level of Lp(a) than Europeans.

What is lipoprotein(a) ?

Description : What is lipoprotein(a) ?

Last Answer : It is attached to apo B-100 by a disulfide bond. It has significant homology with plasminogen. So it interferes with plasminogen activation and impairs fibrinolysis (Fig.14.10). This leads to unopposed intravascular thrombosis and possible myocardial infarction.

Highest content of triglycerides is seen in which lipoprotein?

Description : Highest content of triglycerides is seen in which lipoprotein?

Last Answer : Chylomicrons. 

During electrophoresis, what is the least moving lipoprotein?

Description : During electrophoresis, what is the least moving lipoprotein?

Last Answer : Chylomicron (gamma position).

During electrophoresis, what is the fastest moving lipoprotein?

Description : During electrophoresis, what is the fastest moving lipoprotein?

Last Answer : HDL (alpha lipoprotein).

δ-Cells of islet of langerhans of pancreas produce (A) Pancreatic polypeptide (B) Pancreatic lipase (C) Somatostatin (D) Steapsin

Description : δ-Cells of islet of langerhans of pancreas produce (A) Pancreatic polypeptide (B) Pancreatic lipase (C) Somatostatin (D) Steapsin

Last Answer : Answer : C