Description : In acute pancreatitis, the enzyme raised in first five days is (A) Serum amylase (B) Serum lactic dehydrogenase (C) Urinary lipase (D) Urinary amylase
Last Answer : Answer : A
Description : The best test for acute pancreatitis in the presence of mumps is (A) A serological test for mumps (B) Serum amylase (C) Urinary amylase (D) Serum lipase
Last Answer : Answer : D
Description : Maximum rise in serum amylase occurs in (A) Acute parotitis (B) Acute pancreatitis (C) Chronic pancreatitis (D) Pancreatic cancer
Last Answer : Answer : B
Description : Serum amylase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Pancreatic cancer (D) All of these
Description : Serum lipase level increases in (A) Paget’s disease (B) Gaucher’s disease (C) Acute pancreatitis (D) Diabetes mellitus
Last Answer : Answer : C
Description : Serum lipase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Infective hepatitis (D) Biliary obstruction
Description : A 55 year-old female complaining of vague tiredness is found to have a serum corrected calcium concentration of 2.9 mmol/l. Examination was unremarkable. Which of the following results ... 4) Low normal plasma phosphate concentration 5) Low normal serum 25-hydroxyvitamin D concentration
Last Answer : Answers-3 Bit too easy really. A high or even normal PTH concentration in the presence of hypercalcaemia would support the diagnosis of hyperparathyroidism. A high urinary Calcium concentration may ... but neither confirm the diagnosis. Elevated 1,25 VitD suggests a diagnosis of hypervitaminosis D.
Description : Serum ferroxidase level decreases in (A) Gaucher’s disease (B) Cirrhosis of liver (C) Acute pancreatitis (D) Wilson’s disease ENZYMES 143
Description : A 35 year old male presents with weakness and tiredness. He is noted to be hyertensive. Electrolytes show a hypokalaemia and a hypomagnesaemia. What investigation would you select for this patient? ... Plasma renin toaldosterone ratio 3) Serum amylase 4) Serum calcium 5) Oral glucose tolerance test
Last Answer : Answers-2 The hypokalaemic hypertension with hypomagnesaemia suggests primary hyperaldosteronism. The most reliable assessment for this would be renin to aldosterone ratio.
Description : A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of ... serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations
Last Answer : Answers-2 a-An unusual but recognised feature particularly in children. However does not support a diagnosis of DKA. b-Suggests metabolic acidosis. c-'Normoglycaemic DKA' can occur and a glucose ... anorexia. e-Respiratory compensation leads to rapid deep (Kussmaul's) breathing. (Dr Mike Mulcahy)
Description : A 53-year-old man presented with hypertension of 150/110 mmHg. He is generally asymptomatic and has no previous medical history of note. He is a smoker of 5 cigarettes daily and drinks ... Adrenocortical adenoma 2) Bartter's syndrome 3) Liddle's syndrome 4) Liquorice ingestion 5) Pheochromocytoma
Last Answer : Answers-1 This patient is most likely to have Conn's syndrome as reflected by the hypokalaemic hypertension. Liquorice ingestion or Liddle's syndrome are again possible causes of ... hypertension (often diastolic hypertension), muscular weakness, paresthesias, headache, polyuria, and polydipsia."
Description : An Afro-Carribean male aged 48 years presents with gradual onset of exertional dyspnoea, non productive cough, malaise, weight loss and polyarthralgia. Schirmers test indicates a dry eye. X-ray ... 2) Serum phosphorus 3) Urea and electrolytes 4) Thallium Scan 5) Quantitative Immunoglobulins.
Last Answer : Answers-4 This condition is sarcoidosis. Serum calcium, Serum phosphorus, Chem7 and Chem 20 and Quantitative Immunoglobulins are all used in establishing the diagnosis. Gallium scan is helpful in ... areas of poor perfusion. It is particularly used in cardiology to detect areas of ischaemia.
Description : True statements concerning hypoadrenal shock include which of the following? A. Adrenocortical insufficiency may manifest itself as severe shock refractory to volume and pressor therapy. B. ... test should be performed to help establish the diagnosis of acute adrenocortical insufficiency.
Last Answer : Answer: AD DISCUSSION: Shock due to acute adrenocortical insufficiency is relatively uncommon but must be considered when shock refractory to volume replacement and pressor therapy is present. ... and it is the corticosteroid of choice while the ACTH stimulation test is being performed
Description : In Vitamin D poisoning (hyper-vitaminosis) (A) Both serum and urinary “Ca” (B) The serum Ca is low and urinary calcium high (C) The serum “Ca” is increased and urinary “Ca” is normal (D) Both serum and urinary “Ca” are low
Description : Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase
Description : Genetic engineering requires enzyme: (A) DNA ase (B) Amylase (C) Lipase (D) Restriction endonuclease
Description : An enzyme which brings about lysis of bacterial cell wall is (A) Amylase (B) Lysozyme (C) Trypsin (D) Lipase
Description : An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase
Description : An early diagnosis of vitamin C deficiency can be made by (A) Measuring plasma ascorbic acid (B) Measuring urinary ascorbic acid (C) Ascorbic acid saturation test (D) All of these
Description : Sweat chlorides are increased in (A) Cystic fibrosis (B) Pancreatic cancer (C) Acute pancreatitis (D) None of these
Description : The slow moving fraction of LDH is typically increased in pancreas with (A) Cerebrovascular accidents (B) Acute myocardial infarction (C) Acute pancreatitis (D) Acute viral hepatits
Description : Acute pancreatitis is characterised by (A) Lack of synthesis of zymogen enzymes (B) Continuous release of zymogen enzymes into the gut (C) Premature activation of zymogen enzymes (D) Inactivation of zymogen enzymes
Description : Acute pancreatitis can be diagnosed by estimating which enzymes?
Last Answer : Amylase and lipase.
Description : Which of the following statement(s) is/are true concerning the diagnosis and management of hypovolemic shock? a. A fall in hematocrit or hemoglobin always accompanies hemorrhagic shock b. The ... d. Complications are less frequent after treatment of hemorrhagic shock than septic or traumatic shock
Last Answer : Answer: d Hypovolemic shock is readily diagnosed when there is an obvious source of volume loss and overt signs of hemodynamic instability and increased adrenergic output are present. ... response systems and consequences of their disseminated, indiscriminate cellular injury can be quite profound
Description : Which of the following statements reflect what is known about the Ebola and Marburg viruses? a) The diagnosis should be considered in a patient who has a febrile, hemorrhagic illness after ... fever, rash, and encephalitis which progress rapidly to profound hemorrhage, organ destruction, and shock.
Last Answer : a) The diagnosis should be considered in a patient who has a febrile, hemorrhagic illness after traveling to Asia or Africa. The diagnosis should be considered in a patient who has a febrile, ... Asia or Africa, or who has handled animals or animal carcasses from those parts of the world.
Description : In order to be effective, Percutaneous Transluminal Coronary Angioplasty (PTCA) must be performed within what time frame, beginning with arrival at the emergency department after diagnosis of myocardial ... during which streptokinase will not be used again in the same patient for acute MI.
Last Answer : a) 60 minutes The sixty minute interval is known as “door to balloon time” for performance of PTCA on a diagnosed MI patient.
Description : Which of the following is a characteristic feature of acute intermittent porphyria? 1) autosomal recessive inheritance 2) excessive faecal protoporphyrin excretion 3) excessive urinary porphobilinigoen between acute attacks 4) hypernatraemia during attacks 5) photosensitivity
Last Answer : Answers-3 Features of acute intermittent porphyria include urinary porphobilinogen excretion raised between attacks, hyponatraemia during an acute attack and autosomal dominant inheritance.
Description : Which of the following is the most common cause of Hypothyroidism in iodine sufficient area? Options: 1) Iatrogenic hypothyroidism 2) Post-partum thyroiditis 3) Autoimmune thyroiditis 4) Thyroid aplasia
Last Answer : Correct Answer: 3) Autoimmune thyroiditis
Description : A 20 yr. old female patient presents with pain in thyroid region of the neck since few days. She gives recent history of mumps. On palpation thyroid is tender and her thyroid function ... 1) de Quervain's thyroiditis 2) Silent thyroiditis 3) Primary thyrotoxicosis 4) Hashimoto's thyroiditis
Last Answer : Correct Answer: 1) de Quervain’s thyroiditis
Description : A middle aged female presented with following symptoms - Hirsutism, fragility of skin, with easy bruising, broad purplish striae and signs of proximal myopathy. The first step in ... Exclude exogenous Glucocorticoid use 3) Advice plasma ACTH estimation 4) Advice dexamethasone overnight test
Last Answer : Correct Answer: 2) Exclude exogenous Glucocorticoid use
Description : Which one of the following pairs is wrongly matched? (a) Alcohol - Nitrogenase (b) Fruit juice - Pectinase (c) Textile - Amylase (d) Detergents - Lipase
Last Answer : (a) Alcohol - Nitrogenase
Description : Choose the correct enzyme - substrate pair. (a) Carbohydrate - Lipase (b) Maltase - Lactose (c) Rennin - Casein (d) Protein - Amylase
Last Answer : (c) Rennin - Casein
Description : Which one of the following is the correct matching of the site of action on the given substrate, the enzyme acting upon it and the end product? (a) Small intestine : Proteins Pepsin → ... Trypsin → Monoglycerides (d) Small intestine : Starch α-Amylase → Disaccharide (maltose)
Last Answer : (d) Small intestine : Starch α-Amylase → Disaccharide
Description : Gastric juice of infants contains (a) pepsinogen, lipase, rennin (b) amylase, rennin, pepsinogen (c) maltase, pepsinogen, rennin (d) nuclease, pepsinogen, lipase
Last Answer : (a) pepsinogen, lipase, rennin
Description : Which of the following options best represents the enzyme composition of pancreatic juice? (a) Amylase, Pepsin, Trypsinogen, Maltase (b) Peptidase, Amylase, Pepsin, Rennin (c) Lipase, Amylase, Trypsinogen, Procarbo- xypeptidase (d) Amylase, Peptidase, Trypsinogen, Rennin
Last Answer : (c) Lipase, Amylase, Trypsinogen, Procarbo- xypeptidase
Description : An enzyme that can stimulate germination of barley seeds is (a) invertase (b) α-amylase (c) lipase (d) protease.
Last Answer : (b) α-amylase
Description : Pancreatic juice contains more than one enzyme. Which among the following combination is correct ? (1) Pepsin and Lipase (2) Amylase and Pepsin (3) Pepsin and Trypsin (4) Trypsin and Lipase
Last Answer : 4) Trypsin and Lipase
Description : Which of the following options best represents the enzyme composition of pancreatic juice ? (1) amylase, pepsin, trypsinogen, maltase (2) peptidase, amylase, pepsin, rennin (3) lipase, amylase, trypsinogen, procarboxypeptidase (4) amylase, peptidase, trypsinogen, rennin
Last Answer : (3) lipase, amylase, trypsinogen, procarboxypeptidase
Description : The enzyme which is used for the digestion of fat is (a) Water (b) Bile (c) Amylase (d) Lipase
Last Answer : (d) Lipase
Description : Some proteolytic enzymes are (C.P.M.T. 77) (a) Trypsin, peptidase, pepsin (b) Amylopsin, steapsin, ptyalin (c) Amylase, lipase, zymase (d) Urease, zymase, dehydrogenase
Last Answer : (a) Trypsin, peptidase, pepsin
Description : Which of the following converts peptones, proteoses and polypeptides into amino acids : (a) Amylase (b) Trypsin (c) Lipase (d) Rennin
Last Answer : (b) Trypsin
Description : Emulsified fat is acted upon by : (a) Lipase (b) Amylase (c) Rennin (d) Pepsin
Last Answer : (a) Lipase
Description : The enzyme for starch digestion (a) Maltase (b) Invertase (c) Lipase (d) Amylase
Last Answer : (d) Amylase
Description : Which of the following human digestive enzymes is incorrectly matched to its substrate? a) pepsin - protein b) trypsin - starch (pron: TRIP-sin) c) pancreatic amylase - starch (pron: AM-i-lase) d) lipase - fat e) maltase - maltose.
Last Answer : ANSWER: B -- TRYPSIN - STARCH
Description : If a fibrinolytic drug is used for treatment of acute myocardial infarction, the adverse drug effect that is most likely to occur is (a) Acute renal failure (b) Development of antiplatelet antibodies (c) Encephalitis secondary to liver dysfunction (d) Hemorrhagic stroke (e) Neutropenia
Last Answer : Ans: D
Description : Radiological ‘Colon cut off sign’ is seen in Options: 1) Acute intussusception 2) Acute lobar pneumonia 3) Acute pancreatitis 4) Crohn’s disease
Last Answer : Correct Answer: 3) Acute pancreatitis
Description : Kehr’s sign is a classical feature of Options: 1) Rupture of liver 2) Acute pancreatitis 3) Acute intestinal obstruction 4) Rupture of spleen
Last Answer : Correct Answer: 4) Rupture of spleen
Description : Laboratory diagnosis of vitamin B12 deficiency can be made by measuring the urinary excretion of (A) Xanthurenic acid (B) Formiminoglutamic acid (C) Methylmalonic acid (D) Homogentisic acid
Description : Which of the following techniques would be most useful in the differential diagnosis between ectopic Cushing's syndrome and pituitary dependent Cushing's disease. 1) Urine free cortisol 2) ... Dexamethasone suppression test 3) ACTH concentrations 4) Inferior petrosal sinus sampling 5) CRF test
Last Answer : Answers-4 Inferior petrosal sinus sampling with an elevated central ACTH concentration compared with the peripheral value is the most valuable test in the differential diagnosis of either Cushing's disease or ectopic Cushing's syndrome. The other tests are far less useful in comparison.