Description : Which statement is wrong for Krebs' cycle? (a) There is one point in the cycle where FAD+ is reduced to FADH2. (b) During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised. (c ... citric acid. (d) There are three points in the cycle where NAD+ is reduced to NADH + H+.
Last Answer : (c) The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid.
Description : In the biosynthesis of the iron protoporphyrin, the product of the condensation between succinyl-CoA and glycine is (A) α-Amino β-ketoadipic acid (B) δ-Aminolevulinate (C) Hydroxymethylbilane (D) Uroporphyrinogen I
Last Answer : Answer : A
Description : Heme is synthesized from (A) Succinyl-CoA and glycine (B) Active acetate and glycine (C) Active succinate and alanine (D) Active acetate and alanine
Description : In purine biosynthesis ring closure in the molecule formyl glycinamide ribosyl-5- phosphate requires the cofactors: (A) ADP (B) NAD (C) FAD (D) ATP and Mg++
Last Answer : Answer : D
Description : DNA ligase of E. coli requires which of the following co-factors? (A) FAD (B) NAD+ (C) NADP+ (D) NADH
Last Answer : Answer : B
Description : Retinol and retinal are interconverted requiring dehydrogenase or reductase in the presence of (A) NAD or NADP (B) NADH + H+ (C) NADPH (D) FAD
Description : Retinal is reduced to retinol in intestinal mucosa by a specific retinaldehyde reductase utilising (A) NADPH + H+ (B) FAD (C) NAD (D) NADH + H+
Description : In β−oxidation of fatty acids which of the following are utilized as co-enzymes? (A) NAD+ and NADP+ (B) FAD H2 and NADH + H+ (C) FAD and FMN (D) FAD and NAD+
Description : In β-Oxidation of fatty acids, which of the following are utilized as coenzymes? (A) NAD+ and NADP+ (B) FADH2 and NADH + H+ (C) FAD and FMN (D) FAD and NAD+
Description : For reduction enzyme HMG-CoA reductase requires cofactor: (A) NADPH (B) NADP (C) NAD (D) FAD
Description : Mitochondrial α-ketoglutarate dehydrogenase complex requires all the following to function except (A) CoA (B) FAD (C) NAD+ (D) NADP+
Description : β-Oxidation of fatty acids requires all the following coenzymes except (A) CoA (B) FAD (C) NAD (D) NADP
Description : The transaminase activity needs the coenzyme: (A) ATP (B) B6 – PO4 (C) FAD+ (D) NAD+
Description : Excessive intake of ethanol increases the ratio: (A) NADH : NAD+ (B) NAD+ : NADH (C) FADH2 : FAD (D) FAD : FADH2
Last Answer : A
Description : Histamine is formed from histidine by the enzyme histidine decarboxylase in the presence of (A) NAD (B) FMN (C) HS-CoA (D) B6-PO4
Description : During each cycle of β-oxidation of fatty acid, all the following compounds are generated except (A) NADH (B) H2O (C) FAD (D) Acyl CoA
Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis
Description : In Krebs’ cycle, the FAD precipitates as electron acceptor during the conversion of (a) fumaric acid to malic acid (b) succinic acid to fumaric acid (c) succinyl CoA to succinic acid (d) α-ketoglutarate to succinyl CoA.
Last Answer : (b) succinic acid to fumaric acid
Description : The example of generation of a high energy phosphate at the substrate level in the citric acid cycle is the reaction: (A) Isocitrate α-Ketoglutarate (B) Succinate α-fumarate (C) Malate α-oxaloacetate (D) Succinyl CoA α-Succinate
Description : The reaction succinyl COA to succinate requires (A) CDP (B) ADP (C) GDP (D) NADP+
Last Answer : B
Description : Magnesium ions are required in the reactions involving (A) NAD (B) FAD (C) ATP (D) CoA
Last Answer : Answer : C
Description : Group transferring Co-enzyme is (A) CoA (B) NAD+ (C) NADP+ (D) FAD+
Description : Pyruvate dehydrogenase contains all except (A) Biotin (B) NAD (C) FAD (D) CoA
Description : The coenzyme involved in dehydrogenation of 3-hydroxy acyl-CoA is (A) FAD (B) FMN (C) NAD (D) NADP
Description : In β-oxidation, the coenzyme for acyl-CoA dehydrogenase is (A) FMN (B) NAD (C) NADP (D) FAD
Description : The coenzyme not involved in the formation of acetyl-CoA from pyruvate is (A) TPP (B) Biotin (C) NAD (D) FAD
Description : An examp le of group transferr ing coenzyme is (A) NAD+ (B) NADP+ (C) FAD (D) CoA
Description : The cofactor or its derivative required for the conversion of acetyl CoA to malonylCoA is (A) FAD (B) ACP (C) NAD+ (D) Biotin
Description : Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+
Description : Carboxylation of acetyl—CoA to malonyl — CoA takes place in presence of (A) FAD+ (B) Biotin (C) NAD+ (D) NADP+
Description : Acyl-CoA dehydrogenase converts Acyl CoA to α-β unsaturated acyl-CoA in presence of the coenzyme: (A) NAD+ (B) NADP+ (C) ATP (D) FAD
Description : Conversion of all-trans-retinal into alltrans-retinol requires (A) NAD (B) NADH (C) NADP (D) NADPH
Description : A coenzyme required for the synthesis of glycine from serine is (A) ATP (B) Pyridoxal phosphate (C) Tetrahydrofolate (D) NAD
Description : Sulphur containing coenzyme is (A) NAD (B) FAD (C) Pyridoxal phosphate (D) Biotin
Description : Vitamin B2 is component of coenzyme: (A) Pyridoxal phosphate (B) TPP (C) NAD (D) FMN/FAD
Description : The hydrogen acceptor used in pentose phosphate pathway is (A) NAD (B) NADP (C) FAD (D) FMN
Description : For synthesis of sphingosine, all the following coenzymes are required except (A) Pyridoxal phosphate (B) NADPH (C) FAD (D) NAD
Description : In the biosynthesis of triglycerides from glycerol 3-phosphate and acyl-CoA, the first intermediate formed is (A) 2-Monoacylglycerol (B) 1, 2-Diacylglycerol (C) Lysophosphatidic acid (D) Phosphatidic acid
Description : Decarboxylation of α-keto acids requires (A) Thiamine pyrophosphate, FAD, NAD+ (B) Flavin mononucleotide (C) NADP+ (D) NAD+ only
Description : UDP glucose is converted to UDP glucurronate, a reaction catalysed by UDP glucose dehydrogenase requires (A) NAD+ (B) FAD (C) NADP (D) FMN
Description : Conversion of tyrosine to dihydroxyphenylalanine is catalysed by tyrosine hydroxylase which requires (A) NAD (B) FAD (C) ATP (D) Tetrahydrobiopterin
Description : Retinal is reduced to retinol by retinene reductase in presence of the coenzyme (A) NAD+ (B) NADP+ (C) NADH + H+ (D) NADPH + H+
Description : NAD is required as a coenzyme for (A) Malate dehydrogenase (B) Succinate dehydrogenase (C) Glucose-6-phosphate dehydrogenase (D) HMG CoA reductae
Description : The source of all the carbon atoms in cholesterol is (A) Acetyl-CoA (B) Bicarbonate (C) Propionyl-CoA (D) Succinyl-CoA
Description : Conversion of fatty acyl-CoA to an acylCoA derivative having 2 more carbon atoms involves as acetyl donar: (A) Acetyl-CoA (B) Succinyl-CoA (C) Propionyl-CoA (D) Malonyl-CoA
Description : In extra hepatic tissues, one mechanism for utilization of acetoacetate involves (A) Malonyl-CoA (B) Succinyl-CoA (C) Propionyl-CoA (D) Acetyl-CoA
Description : Fatty acids with odd number of carbon atoms yield acetyl-CoA and a molecule of (A) Succinyl-CoA (B) Propionyl-CoA (C) Malonyl-CoA (D) Acetoacetyl-CoA
Description : Formation of succinyl-CoA from α-Ketoglutarate is inhibited by (A) Fluoroacetate (B) Arsenite (C) Fluoride (D) Iodoacetate
Description : β-Oxidation of odd-carbon fatty acid chain produces (A) Succinyl CoA (B) Propionyl CoA (C) Acetyl CoA (D) Malonyl CoA
Description : Succinyl CoA is utilised for what purposes?
Last Answer : Porphyrin biosynthesis, activation of acetoacetate, and oxidation in TCA cycle.