Description : Menke’s disease (Kinky or steel hair disease) is a X-linked disease characterized by (A) High levels of plasma copper (B) High levels of ceruloplasmin (C) Low levels of plasma copper and of ceuloplasmin (D) High level of hepatic copper
Last Answer : Answer : C
Description : All of the following statements about Tangier disease are true except (A) It is a disorder of HDL metabolism (B) Its inheritance is autosomal recessive (C) Apoproteins A-I and A-II are not synthesised (D) Plasma HDL is increased
Last Answer : Answer : D
Description : Menke’s disease is due to an abnormality in the metabolism of (A) Iron (B) Manganese (C) Magnesium (D) Copper
Description : Ceruloplasmin is absent in (A) Cirrhosis of liver (B) Wilson’s disease (C) Menke’s disease (D) Copper deficiency
Last Answer : Answer : B
Description : Zinc deficiency occurs commonly in (A) Acrodermatitis enteropathica (B) Wilson’s disease (C) Xeroderma pigmentosum (D) Menke’s disease
Description : All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it
Description : All the following statements about cystic fibrosis are correct except (A) It is inherited as an autosomal recessive disease (B) It affects a number of exocrine glands (C) It causes increased sweating (D) Sweat chlorides are above 60 mEq/L in this disease
Description : Abnormal collagen structure is seen in all of the following except (A) I-cell disease (B) Osteogenesis imperfecta (C) Menke’s disease (D) Ehlers-Danlos sydrome
Description : In Wilson’s disease (A) Copper fails to be excreted in the bile (B) Copper level in plasma is decreased (C) Ceruloplasmin level is increased (D) Intestinal absorption of copper is decreased
Last Answer : Answer : A
Description : All of the following statements about primary gout are true except (A) Uric acid stones may be formed in kidneys (B) Arthritis of small joints occurs commonly (C) Urinary excretion of uric acid is decreased (D) It occurs predominantly in males
Description : All the following statements about restriction fragment length polymorphism are true except (A) It results from mutations in restriction sites (B) Mutations in restriction sites can occur in coding or non- ... It is inherited in Mendelian fashion (D) It can be used to diagnose any genetic disease
Description : All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease
Description : Wilson's disease is an inherited disorder in which excessive amounts of ________ accumulate in the body.
Last Answer : Copper
Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte
Last Answer : C
Description : All of the following are true of Wilson’s disease except (A) Low total plasma Cu (B) Elevated urinary copper (C) Arthritis (D) Aminoaciduria
Description : All of the following statements about bronzed diabetes are true except (A) It is caused by excessive intake of copper (B) Skin becomes pigmented (C) There is damage to β cells of Islets of Langerhans (D) Liver is damaged
Description : Which of the following statement(s) is/are true concerning metabolic derangements in sepsis and the systemic inflammatory response syndrome which may follow progressive shock? a. Alterations in glucose ... The serum aromatic amino acids fall rapidly as they are actively used in oxidative metabolism
Last Answer : Answer: b, c A broad spectrum of metabolic abnormalities become apparent in sepsis and the systemic inflammatory response syndrome following shock. Disruption of the normal cycles of carbohydrate, ... acetyl coenzyme A. This results in reduced serum level of leucine, isoleucine and valine
Description : A number of changes in trace mineral metabolism are noted during sepsis. Which of the following change(s) may be observed in a septic or trauma patient? a. Plasma iron levels are noted to ... are noted to decrease c. Plasma serum zinc levels may decrease d. Administration of iron is appropriate
Last Answer : Answer: a, c Changes in the balance of magnesium, inorganic phosphate, zinc, and potassium generally follow alterations in nitrogen balance. Although the iron-binding capacity of transferrin ... concentrations can be ascribed almost entirely to the levels of the ceruloplasmin produced by the liver
Description : Answer: a, b, c, d Free oxygen radicals are chemical species that are intermediates in the normal process of cellular respiration. Oxidants that are free radicals have been implicated as initiators of ... a. C-reactive protein b. Serum amyloid c. a -Proteinase inhibitor d. Fibrinogen e. Albumin
Last Answer : Answer: a, b, c, d The acute-phase response is a series of homeostatic responses of the organism to tissue injury in infection and inflammation. After an inflammatory stimulus occurs, a number ... 30% to 50% of the level before injury. The reason for the decrease in production is poorly understood
Description : Which group of three of the following five statements (1-5) contain all three correct statements regarding beri-beri? 1. A crippling disease prevalent among the native population of sub-Saharan Africa. 2. A deficiency disease caused by lack ... and 5 (b) 1, 2 and 4 (c) 1, 3 and 5 (d) 2, 3 and 5
Last Answer : a) 2, 4 and 5
Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.
Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.
Description : The normal content of protein bound iron (PBI) in the plasma of males is (A) 120–140 µg/100 ml (B) 200–300 µg/100 ml (C) 120–140 µg/100 ml (D) 200–300 µg/100 ml
Description : 'Gynecomastia' is - (1) Development of hair on ears in males (2) Increased height in females (3) Development of an extra finger in females (4) Development of breasts in males
Last Answer : (4) Development of breasts in males Explanation: Gynecomastia is swelling of the breast tissue in boys or men, caused by an imbalance of the hormones estrogen and testosterone. The development ... in the ratio of estrogens/androgens are thought to be responsible for the development of gynecomastia.
Description : ‘Gynecomastia’ is (1) Development of hair on ears in males (2) Increased height in females (3) Development of an extra finger in females (4) Development of breasts in males
Last Answer : Development of breasts in males
Description : All the following statements about retino blastoma are true except (A) At least two mutations are required for its development (B) One mutation can be inherited from a parent (C) Children ... mutation develop retinoblastoma at a younger age (D) RB 1 gene promotes the development of retinoblastoma
Description : Are there any males who suffer from Body Dysmorphic Disorder or is it only found in women?
Last Answer : answer:According to wikipedia Although originally a mental-illness diagnosis usually applied to women, body dysmorphic disorder occurs equally among men and women, and occasionally in children and older ... body dysmorphic disorder. Not exactly medical citations, but all I could find right now.
Description : In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased
Description : The plasma protein bound fraction of a drug: A. Contributes to the response at the given moment B. Remains constant irrespective of the total drug concentration C. Remains constant irrespective of the disease state D. Is not available for metabolism unless actively extracted by the liver
Last Answer : D. Is not available for metabolism unless actively extracted by the liver
Description : Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in ... with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure
Last Answer : Answers-2 Hyperuricaemia may be due to increased purine intake, urate production or reduced urate clearance, and is most commonly due to the latter. Therefore it can occur in association with enhanced ... . Many of the uricosuric drugs may be detrimental in renal failure and may not be effective.
Description : A tendency towards some anxiety disorder can be inherited?
Last Answer : 1
Description : Why are grey/white hairs all "kinky"?
Last Answer : Here ya go.
Description : What are good kinky dares?
Last Answer : Need answer
Description : Prazosin is an effective antihypertensive while nonselective a adrenergic blockers are not because (a) It is the only orally active a blocker (b) It improves plasma lipid profile (c) It does not concurrently enhance noradrenaline release (d) It improves urine flow in males with prostatic hypertrophy
Last Answer : Ans: C
Description : Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy
Last Answer : C. It does not concurrently enhance noradrenaline release
Description : The carbon atom wh ich becomes asymmetric when the straight chain form of monosaccharide changes into ring form is known as CARBOHYDRATES AND CARBOHYDRATE METABOLISM 9 (A) Anomeric carbon atom (B) Epimeric carbon atom (C) Isomeric carbon atom (D) None of these
Last Answer : A
Description : The Tm for PAH i.e the maximal secretory capacity of the tubule for PAH can be used to gavge the (A) Extent of tubular damage FATS AND FATTY ACID METABOLISM 81 (B) Impairment of the capacity of the tubule to perform osmotic work (C) Impairment of renal plasma flow (D) Glomerular filtration rate
Description : Inherited deficiency of enzyme cerebrosidase produces (A) Fabry’s disease (B) Niemann pick disease (C) Gaucher’s disease (D) Tay-sach’s disease
Description : Tay-Sachs disease results from inherited deficiency of (A) Arylsulphatase A (B) Hexosaminidase A (C) Sphingomyelinase (D) Ceramidase
Description : Inherited deficiency of β−glucosidase causes (A) Tay-Sachs disease (B) Metachromatic leukodystrophy (C) Gaucher’s disease (D) Multiple sclerosis
Description : Eicosanoids mediate inflammation in a variety of ways. Of the following statements, which are true with regard to this? a. Eicosanoids are stored in cytoplasmic granules ... include vasodilatation, vasoconstriction, increased vascular permeability and both chemotaxis and chemoattractant inhibition
Last Answer : Answer: b, d The eicosanoids are derived from arachidonic acid (eicosatetraenoic acid) and consist of prostaglandins, thromboxanes, leukotrienes and lipoxins. The eicosanoids are not ... nervous system d. Mononuclear phagocytes release a variety of proinflammatory cytokines and growth factors
Description : True statements about the pH of the extracellular fluid: a. in healthy people it is maintained between 7.4 and 7.5 b. is increased in hypovolaemic shock c. decreases following a cardiac arrest d. influences the binding of drugs to plasma proteins
Last Answer : . influences the binding of drugs to plasma proteins
Description : With regard to blood groups and blood products: a. the ABO system is inherited in an autosomal dominant pattern b. group O and Rhesus positive is the universal donors' blood. ... dextrose, phosphate and citrate d. stored blood becomes progressively more acidotic and hyperkalaemic with time
Last Answer : stored blood becomes progressively more acidotic and hyperkalaemic with time
Description : Which one of the following is true of IgE? 1) Is present in plasma in the same concentration as IgG 2) Is increased acutely in an asthmatic attack 3) Crosses the normal placenta 4) Is increased in the serum of atopic individuals 5) Is involved in type 2 hypersensitivity
Last Answer : Answers-4 IgG is the predominant form of immunoglobulin in plasma at a concentration around 10,000 times that of IgE. IgG crosses the placenta to confer immunity to the fetus but IgE does ... frequently increased in those with atopy but serum IgE does not rise acutely during an asthmatic attack.
Description : Immediate allergy reaction (type I allergic reaction) is: a) An allergic or immune response that begins within a period lasting from a few minutes to about an hour after exposure to an ... cause tissue damage e) It occurs during blood transfusion reactions and in hemolytic disease of the newborn.
Last Answer : Ans: A
Description : Seminal plasma in human males is rich in (a) fructose and calcium (b) glucose and calcium (c) DNA and testosterone (d) ribose and potassium.
Last Answer : (a) fructose and calcium