Adrneal cortical response is poor in (A) Kwashiorkor (B) Marasmus (C) Fatty liver (D) Atherosclerosis HORMONE METABOLISM 229

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Answer :  A

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Description : Protein deficiency disease is known as (A) Cushing’s disease (B) Fabry’s disease (C) Parkinson’s disease (D) Kwashiorkor and marasmus

Last Answer : Answer : D

Description : Marasmus differs from Kwashiorkor in the which of these following respect (A) Mental retardation occurs in kwashiorkor but not in marasmus (B) Growth is retarded in kwashiorkor but not in marasmus ... in marasmus but not kwashiorkor (D) Subcutaneous fat disappears in marasmus but not in kwashiorkor

Last Answer : Answer : D

Description : Insulin receptors are decreased in number in (A) Obesity (B) Starvation (C) Hyperinsulinism (D) Kwashiorkor HORMONE METABOLISM 221

Last Answer : Answer : A

Description : Following replacement of breast feeding by less nutritive food, low in proteins and calories, infants below the age of one year suffer from: (a) kwashiorkor (b) marasmus (c) rickets (d) pellagra

Last Answer : Ans:(c)

Description : When breast feeding is replaced by less nutritive food low in proteins and calories; the infants below the age of one year are likely to suffer from (a) rickets (b) kwashiorkor (c) pellagra (d) marasmus.

Last Answer : (d) marasmus.

Description : Marasmus occurs from deficient intake of (A) Essential amino acids (B) Essential fatty acids (C) Calories (D) Zinc

Last Answer : Answer : C

Description : Kwashiorkor occurs when the diet is severely deficient in (A) Iron (B) Calories (C) Proteins (D) Essential fatty acids

Last Answer : Answer : C

Description : Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly (A) Taken up by liver (B) Taken up by extrahepatic tissues (C) Reutilised in adipose tissue (D) Excreted from the body FATS AND FATTY ACID METABOLISM 85

Last Answer : Answer : A

Description : A dietary deficiency in both the quantity and the quality of protein results in (A) Kwashiorkar (B) Marasmus (C) Xerophtalmia (D) Liver diseases

Last Answer : Answer : A

Description : The essential fatty acids retard (A) Atherosclerosis (B) Diabetes mellitus (C) Nepritis (D) Oedema

Last Answer : Answer : A

Description : A bland diet is recommended in (A) Peptic ulcer (B) Atherosclerosis (C) Diabetes (D) Liver disease

Last Answer : Answer : A

Description : The plasma protein bound fraction of a drug: A. Contributes to the response at the given moment B. Remains constant irrespective of the total drug concentration C. Remains constant irrespective of the disease state D. Is not available for metabolism unless actively extracted by the liver

Last Answer : D. Is not available for metabolism unless actively extracted by the liver

Description : The plasma protein bound fraction of a drug: A. Contributes to the response at the given moment B. Remains constant irrespective of the total drug concentration C. Remains constant irrespective of the disease state D. Is not available for metabolism unless actively extracted by the liver

Last Answer : D. Is not available for metabolism unless actively extracted by the liver

Description : The plasma protein bound fraction of a drug: A. Contributes to the response at the given moment B. Remains constant irrespective of the total drug concentration C. Remains constant irrespective of the disease state D. Is not available for metabolism unless actively extracted by the liver

Last Answer : D. Is not available for metabolism unless actively extracted by the liver

Description : All of the following substances have been used to estimate GFR except (A) Inulin (B) Creatinine (C) Phenol red (D) Mannitol FATS AND FATTY ACID METABOLISM 105

Last Answer : Answer : C

Description : During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103

Last Answer : Answer : A

Description : The major source of cholesterol in arterial smooth muscle cells is from (A) IDL (B) LDL (C) HDL (D) Chylomicrons FATS AND FATTY ACID METABOLISM 101

Last Answer : Answer : B

Description : HMG CoA is formed in the metabolism of (A) Cholesterol, ketones and leucine (B) Cholesterol, fatty acid and Leucine (C) Lysine, Lecuine and Isoleucine (D) Ketones, Leucine and Lysine

Last Answer : Answer : A

Description : Cholesterol is excreted as such into ________. (A) Urine (B) Faeces (C) Bile (D) Tears FATS AND FATTY ACID METABOLISM 99

Last Answer : Answer : C

Description : Rancidity of butter is prevented by the addition of (A) Vitamin D (B) Tocopherols (C) Presence of priotin (D) Presence of ‘Cu’ FATS AND FATTY ACID METABOLISM 97

Last Answer : Answer : B

Description : All active prostaglandins have atleast one double bond between positions: (A) 7 and 8 (B) 9 and 10 (C) 11 and 12 (D) 13 and 14 FATS AND FATTY ACID METABOLISM 95

Last Answer : Answer : A

Description : Instead of ester link plasmalogens possess an other link in position: (A) α (B) β (C) γ (D) None of these FATS AND FATTY ACID METABOLISM 93

Last Answer : Answer : B

Description : In haemolytic jaundice, urine shows (A) Absence of bile pigments and urobilinogen (B) Presence of bile pigments and urobilinogen (C) Absence of bile pigments and presence of urobilinogen (D) Presence of bile pigments and absence of urobilinogen FATS AND FATTY ACID METABOLISM 91

Last Answer : Answer : C

Description : Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89

Last Answer : Answer : A

Description : One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains (A) One —SH group (B) Two —SH groups (C) Three —SH groups (D) Four —SH groups FATS AND FATTY ACID METABOLISM 87

Last Answer : Answer : B

Description : Propionyl CoA is formed on oxidation of (A) Monounsaturated fatty acids (B) Polyunsaturated fatty acids (C) Fatty acids with odd number of carbon atoms (D) None of these FATS AND FATTY ACID METABOLISM 83

Last Answer : Answer : C

Description : The Tm for PAH i.e the maximal secretory capacity of the tubule for PAH can be used to gavge the (A) Extent of tubular damage FATS AND FATTY ACID METABOLISM 81 (B) Impairment of the capacity of the tubule to perform osmotic work (C) Impairment of renal plasma flow (D) Glomerular filtration rate

Last Answer : Answer : A

Description : Normal quantity of urobilinogen excreted in the feces per day is about (A) 10–25 mg (B) 50–250 mg (C) 300–500 mg (D) 700–800 mg FATS AND FATTY ACID METABOLISM 79

Last Answer : Answer : B

Description : Ochronosis is an important finding of (A) Tyrosinemia (B) Tyrosinosis (C) Alkaptonuria (D) Richner Hanhart syndrome FATS AND FATTY ACID METABOLISM 77

Last Answer : Answer : C

Description : Palmitic, oleic or stearic acid ester of cholesterol used in manufacture of cosmetic creams is (A) Elaidic oil (B) Lanoline (C) Spermaceti (D) Chaulmoogric oil FATS AND FATTY ACID METABOLISM 75

Last Answer : Answer : B

Description : Degradation of proteins to amino acids, glucose from carbohydrates and fatty acids from lipids is known as (A) Anabolism (B) Metabolism (C) Catabolism (D) Cretinism

Last Answer : Answer : C

Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate

Last Answer : A

Description : Marasmus is due to malnutrition of (A) Proteins (B) Proteins and calories (C) Proteins and vitamins (D) Proteins and minerals

Last Answer : Answer : B

Description : A characteristic feature of marasmus is (A) Severe hypoalbuminemia (B) Normal epinephrine level (C) Mild muscle wasting (D) Low insulin and high cortisol level

Last Answer : Answer : D

Description : The deficiency of both energy and protein causes (A) Marasmus (B) Kwashiorkar (C) Diabetes (D) Beri-beri

Last Answer : Answer : A

Description : Potassium metabolism is regulated by the hormone: (A) Aldosterone (B) PTH (C) Somatostatin (D) Estrogen

Last Answer : Answer : A

Description : The metabolism of sodium is regulated by the hormone: (A) Insulin (B) Aldosterone (C) PTH (D) Somatostatin

Last Answer : Answer : B

Description : Which of the following hormones is not involved in carbohydrate metabolism? (A) ACTH (B) Glucagon (C) Vasopressin (D) Growth hormone

Last Answer : Answer : C

Description : Hormones act only on specific organs or tissues. These are called (A) Active sites (B) Reaction centre (C) Target organ/Tissue(D) Physiological site HORMONE METABOLISM 231

Last Answer : Answer : C

Description : The second messenger for many hormones is (A) ATP (B) cyclic AMP (C) cGMP (D) UTP HORMONE METABOLISM 227

Last Answer : Answer : B

Description : Placenta secretes all of the following except (A) FSH (B) Progesterone (C) Estrogen (D) Chorionic gonadotropin HORMONE METABOLISM 225

Last Answer : Answer : A

Description : Zona glomerulosa of adrenal cortex synthesises (A) Glucocorticoids (B) Mineralocorticoids (C) Androgens (D) Estrogen and progesterone HORMONE METABOLISM 223

Last Answer : Answer : A

Description : Acromegaly results from overproduction of (A) ACTH during childhood (B) TSH during adult life (C) Growth hormone during childhood (D) Growth hormone during adult life HORMONE METABOLISM 219

Last Answer : Answer : D

Description : Secretion of MSH is regulated by (A) Feedback mechanism (B) Melatonin (C) Hypothalamic hormones (D) ACTH HORMONE METABOLISM 217

Last Answer : Answer : C

Description : Conversion of testosterone to estradiol requires the enzyme: (A) Aromatase (B) Dehydrogenase (C) Lyase (D) Isomerase HORMONE METABOLISM 215

Last Answer : Answer : A

Description : The half life of insulin is (A) < 3–5 minutes (B) < 8–10 minutes (C) < 15 minutes (D) < 15 minutes HORMONE METABOLISM 213

Last Answer : Answer : A

Description : The normal serum level of triiodothyronine (T3) is (A) 0.2–0.5 ng/ml (B) 0.7–2.0 ng/ml (C) 2.0–4.0 ng/ml (D) 5.0–8.0 ng/ml HORMONE METABOLISM 211

Last Answer : Answer : B

Description : The defect in adrenal cortex responsible for lack of glucocorticoids and mineralcorticoids is (A) Androstenedione deficiency (B) 17 α -OH progesterone deficiency (C) C-21 hydroxylase deficiency (D) Testosterone deficiency HORMONE METABOLISM 209

Last Answer : Answer : C

Description : A hormone secreted from posterior pituitary is (A) Vasopressin (B) Thyrotropic hormone (C) Prolactin (D) Adrenocorticotropic hormone CHAPTER 8 CHAPTER 8 HORMONE METABOLISM ABOLISM

Last Answer : Answer : A

Description : Kwashiorkor results from (A) Vitamin A deficiency (B) Vitamin D deficiency (C) Deficiency of minerals in diet (D) Protein and caloric deficiency in diet

Last Answer : Answer : D