Description : Aspirin blocks the synthesis of (A) Prostaglandins only (B) Prostacyclins only (C) Thromboxanes only (D) All of these
Last Answer : Answer : D
Description : Slow reacting Substance of Anaphylaxis is a mixture of (A) Prostaglandins (B) Prostacyclins (C) Thromboxanes (D) Leukotrienes
Description : Cyclo-oxygenase is involved in the synthesis of (A) Prostaglandins (B) Thromboxanes (C) Both (A) and (B) (D) None of these
Last Answer : Answer : C
Description : Lipo-oxygenase is required for the synthesis of (A) Prostaglandins (B) Leukotrienes (C) Thromboxanes (D) All of these
Last Answer : Answer : B
Description : Anti-inflammatory corticosteroids inhibit the synthesis of (A) Leukotrienes (B) Prostaglandins (C) Thromboxanes (D) All of these
Description : Eicosanoids mediate inflammation in a variety of ways. Of the following statements, which are true with regard to this? a. Eicosanoids are stored in cytoplasmic granules ... include vasodilatation, vasoconstriction, increased vascular permeability and both chemotaxis and chemoattractant inhibition
Last Answer : Answer: b, d The eicosanoids are derived from arachidonic acid (eicosatetraenoic acid) and consist of prostaglandins, thromboxanes, leukotrienes and lipoxins. The eicosanoids are not ... nervous system d. Mononuclear phagocytes release a variety of proinflammatory cytokines and growth factors
Description : True statements regarding eicosanoids include which of the following? A. Prostaglandins and thromboxanes are synthesized via the cyclo-oxygenase pathway. B. The vasoconstricting, platelet-aggregating, ... prostaglandins have a short circulation half-life and exert most of their effects locally.
Last Answer : Answer: ABD DISCUSSION: The eicosanoids are a group of compounds arising from the metabolism of arachidonic acid. The prostaglandins and thromboxanes are synthesized via the cyclo-oxygenase ... effects and may be involved in the physiologic responses associated with anaphylactic and septic shock
Description : Which of the following property of prostaglandins has been utilized by chinicians in hospital for (A) Inducing fever (B) Causing inflammation (C) Effecting smooth muscle contraction (D) Disaggregation of spermatozoa
Description : All the following are functions of prostaglandins except (A) Lowering of B.P (B) Introduction of labour (C) Anti inflammatory (D) Prevention of myocardial infraction
Description : One of the important functions of prostacyclins is (A) Inhibition of platelet aggregation (B) Contraction of uterus (C) Decrease of gastric secretion (D) Relieving osthma
Last Answer : Answer : A
Description : Prostaglandins play pathophysiological role in the following except: A. Patency of ductus arteriosus B. Regulation of renal tubular salt absorption C. Ventricular remodeling after myocardial infarction D. Initiation of labour
Last Answer : C. Ventricular remodeling after myocardial infarction
Description : Thromboxanes cause (A) Vasodilation (B) Bronchoconstriction (C) Platelet aggregation (D) All of these
Description : Enhanced facultative reabsorption of water by Vasopressin is mediated by (A) Cyclic AMP (B) Ca++ (C) Cyclic GMP (D) Mg++
Description : Vasopressin (ADH) (A) Enhance facultative reabsorption of water (B) Decreases reabsorption of water (C) Increases excretion of calcium (D) Decreases excretion of calcium
Description : Which of the following hormones is not involved in carbohydrate metabolism? (A) ACTH (B) Glucagon (C) Vasopressin (D) Growth hormone
Description : Increased reabsorption of water from the kidney is the major consequence of which of the following hormones? (A) Cortisol (B) Insulin (C) Vasopressin (D) Aldosterone
Description : Which of the following is noted in cushing’s syndrome, a tumor associated disease of the adrenal cortex? (A) Decreased production of epinephrine (B) Excessive production of epinephrine (C) Excessive production of vasopressin (D) Excessive production of cortisol
Description : __________ hormone is a single chain polypeptide having 32 amino acids with molecular weight of 3,600. (A) Testosteron (B) Thyroxine (C) Calcitonine (D) Vasopressin
Description : Which of the following does not have disulphide bond? (A) Oxytocin (B) Vasopressin (C) Insulin (D) Glucagon
Description : Vasopressin is also known as (A) Antidiabetogenic hormone (B) Antidiuretic hormone (C) Somatotropic hormone (D) Pitoxin
Description : Which of the following hormones are synthesized as prehormones (A) Vasopressin and oxytocin (B) Growth hormone and insulin (C) Insulin and parathyroid hormone (D) Insulin and Glucagon
Description : Diabetes insipidus is caused by deficient secretion of (A) Insulin (B) Glucagon (C) Vasopressin (D) Oxytocin
Description : A hormone synthesised in the hypothalamus is (A) Melatonin (B) Melanocyte stimulating hormone (C) Vasopressin (D) Prolactin
Description : Increased reabsorption of water from the kidney is the major consequence of the secretion of the hormone? (A) Cortisol (B) Insulin (C) Vasopressin (D) Aldosterone
Description : Vasopressin and oxytocin circulate unbound to proteins and have very short plasma half lives, on the order of (A) 1–2 minutes (B) 2–4 minutes (C) 5–8 minutes (D) 10–12 minutes
Description : The hormone required for uterine muscle contraction for child birth is (A) Progesterone (B) Estrogen (C) Oxytocin (D) Vasopressin
Description : A hormone secreted from posterior pituitary is (A) Vasopressin (B) Thyrotropic hormone (C) Prolactin (D) Adrenocorticotropic hormone CHAPTER 8 CHAPTER 8 HORMONE METABOLISM ABOLISM
Description : A hormone secreted from anterior pituitary is (A) Growth hormone (B) Vasopressin (C) Oxytocin (D) Epinephrine
Description : The harmone acting directly on intestinal mucosa and stimulating glucose absorption is (A) Insulin (B) Glucagon (C) Thyroxine (D) Vasopressin
Description : Which of the following hormones is not involved in carbohydrate metabolism? (A) Cortisol (B) ACTH (C) Glucogen (D) Vasopressin
Last Answer : D
Description : The activity of kinins is modulated by (A) Prostaglandins (B) Ca++ (C) Increased cAMP level (D) Increased cGMP level
Description : Which one of the following hormones is derived most completely from tyrosine? (A) Glucagon (B) Thyroxine (C) Insulin (D) Prostaglandins
Description : A cup of strong coffee would be expected to (A) Interfere with synthesis of prostaglandins (B) Decrease the effects of Glucagon (C) Enhance the effects of epinephrine (D) Provide the vitamin nicotinic acid
Description : The suffix number in the names of prostaglandins gives the number of (A) OH groups (B) Double bonds (C) Acid groups (D) Ketoacids
Description : Which of tne of the following scientists has not worked in the field of prostaglandins? (A) Voneuler (B) Sultan Karim (C) Andre robet (D) Kendal
Description : Prostaglandins are (A) C2 unsaturated acids (B) C27 saturated alcohols (C) C20 saturated acids (D) C27 saturated alcohols
Description : Richest source of prostaglandins in a human male is (A) Blood (B) Urine (C) Semen (D) C.S.F.
Description : A cup of strong coffee would be expected to (A) Interfere with the synthesis of prostaglandins (B) Decrease the effect of glucagon (C) Enhance the effect of epinephrine (D) Provide the vitamin nicotinic acid
Description : From arachidonate, synthesis of prostaglandins is catalysed by (A) Cyclooxygenase (B) Lipoxygenase (C) Thromboxane synthase (D) Isomerase
Description : Cholesterol is the precursor for the biosynthesis of (A) fatty acid (B) prostaglandins (C) bile acids (D) sphingmyelin
Description : Acrolein Test is positive for (A) Glycerol (B) Prostaglandins (C) Carbohydrates (D) Proteins
Description : Prostaglandins are synthesized in the body from (A) Myristic acid (B) Arachidonic acid (C) Stearic acid (D) Lignoceric acid
Description : All active prostaglandins have atleast one double bond between positions: (A) 7 and 8 (B) 9 and 10 (C) 11 and 12 (D) 13 and 14 FATS AND FATTY ACID METABOLISM 95
Description : Prostaglandins have a common structure based on prostanoic acid which contains carbon atoms: (A) 12 (B) 16 (C) 18 (D) 20
Description : Prostaglandins are liberated in the circulation by the stimulation of (A) Anterior pituitary glands (B) Posterior pituitary glands (C) Adrenal gland (D) Thyroid gland
Description : The prostaglandins are synthesized from (A) Arachidonic acid (B) Oleic acid (C) Linoleic acid (D) Linolenic acid
Description : Prostaglandins decrease all of the following except (A) Gastric acid secretion (B) Blood pressure (C) Uterine contraction (D) Platelet aggregation
Description : Prostaglandins stimulate (A) Aggregation of platelets (B) Lipolysis in adipose tissue (C) Bronchodilatation (D) Gastric acid secretion
Description : Prostaglandins are inactivated by (A) 15-Hydroxyprostaglandin dehydrogenase (B) Cyclo-oxygenase (C) Lipo-oxygenase (D) None of these
Description : Synthesis of prostaglandins is inhibited by (A) Glucocorticoids (B) Aspirin (C) Indomethacin (D) All of these